-
1
-
-
7644238181
-
Biological robustness
-
Kitano H (2004) Biological robustness. Nat Rev Genet 5(11): 826-837
-
(2004)
Nat Rev Genet
, vol.5
, Issue.11
, pp. 826-837
-
-
Kitano, H.1
-
2
-
-
4544346660
-
Robustness of cellular functions
-
Stelling J, Sauer U, Szallasi Z, Doyle FJ 3rd, Doyle J (2004) Robustness of cellular functions. Cell 118(6): 675-685
-
(2004)
Cell
, vol.118
, Issue.6
, pp. 675-685
-
-
Stelling, J.1
Sauer, U.2
Szallasi, Z.3
Doyle 3rd, F.J.4
Doyle, J.5
-
3
-
-
0033552946
-
Robustness in bacterial chemotaxis
-
Alon U, Surette MG, Barkai N, Leibler S (1999) Robustness in bacterial chemotaxis. Nature 397(6715): 168-171
-
(1999)
Nature
, vol.397
, Issue.6715
, pp. 168-171
-
-
Alon, U.1
Surette, M.G.2
Barkai, N.3
Leibler, S.4
-
4
-
-
0030797355
-
Robustness in simple biochemical networks
-
Barkai N, Leibler S (1997) Robustness in simple biochemical networks. Nature 387(6636): 913-917
-
(1997)
Nature
, vol.387
, Issue.6636
, pp. 913-917
-
-
Barkai, N.1
Leibler, S.2
-
5
-
-
0034712843
-
Robust perfect adaptation in bacterial chemotaxis through integral feedback control
-
Yi TM, Huang Y, Simon MI, Doyle J (2000) Robust perfect adaptation in bacterial chemotaxis through integral feedback control. Proc Natl Acad Sci USA 97(9): 4649-4653
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.9
, pp. 4649-4653
-
-
Yi, T.M.1
Huang, Y.2
Simon, M.I.3
Doyle, J.4
-
6
-
-
0034644270
-
The segment polarity network is a robust developmental module
-
von Dassow G, Meir E, Munro EM, Odell GM (2000) The segment polarity network is a robust developmental module. Nature 406(6792): 188-192
-
(2000)
Nature
, vol.406
, Issue.6792
, pp. 188-192
-
-
von Dassow, G.1
Meir, E.2
Munro, E.M.3
Odell, G.M.4
-
7
-
-
3142517462
-
Topology and robustness in the Drosophila segment polarity network
-
Ingolia NT (2004) Topology and robustness in the Drosophila segment polarity network. PLoS Biol 2(6): E123
-
(2004)
PLoS Biol
, vol.2
, Issue.6
-
-
Ingolia, N.T.1
-
8
-
-
0033517148
-
Robustness of a gene regulatory circuit
-
Little JW, Shepley DP, Wert DW (1999) Robustness of a gene regulatory circuit. Embo J 18(15): 4299-4307
-
(1999)
Embo J
, vol.18
, Issue.15
, pp. 4299-4307
-
-
Little, J.W.1
Shepley, D.P.2
Wert, D.W.3
-
9
-
-
0033574013
-
Biodiversity and ecosystem productivity in a fluctuating environment: The insurance hypothesis
-
Yachi S, Loreau M (1999) Biodiversity and ecosystem productivity in a fluctuating environment: the insurance hypothesis. Proc Natl Acad Sci USA 96(4): 1463-1468
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.4
, pp. 1463-1468
-
-
Yachi, S.1
Loreau, M.2
-
10
-
-
0029661332
-
Complex adaptations and the evolution of evolvability
-
Wagner GP, Altenberg L (1996) Complex adaptations and the evolution of evolvability. Evolution 50(3): 967-976
-
(1996)
Evolution
, vol.50
, Issue.3
, pp. 967-976
-
-
Wagner, G.P.1
Altenberg, L.2
-
11
-
-
0037379626
-
Between genotype and phenotype: Protein chaperones and evolvability
-
Rutherford SL (2003) Between genotype and phenotype: protein chaperones and evolvability. Nat Rev Genet 4(4): 263-274
-
(2003)
Nat Rev Genet
, vol.4
, Issue.4
, pp. 263-274
-
-
Rutherford, S.L.1
-
12
-
-
10744228524
-
Evolution and detection of genetics robustness
-
de Visser J, Hermission J, Wagner GP, Meyers L, Bagheri-Chaichian H, Blanchard J, Chao L, Cheverud J, Elena S, Fontana W et al (2003) Evolution and detection of genetics robustness. Evolution 57(9): 1959-1972
-
(2003)
Evolution
, vol.57
, Issue.9
, pp. 1959-1972
-
-
de Visser, J.1
Hermission, J.2
Wagner, G.P.3
Meyers, L.4
Bagheri-Chaichian, H.5
Blanchard, J.6
Chao, L.7
Cheverud, J.8
Elena, S.9
Fontana, W.10
-
13
-
-
0004068679
-
-
Blackwell Science, Malden, Massachusetts, USA
-
Gerhart J, Kirschner M (1997) Cells, embryos, and evolution: toward a cellular and developmental understanding of phenotypic variation and evolutionary adaptability. Blackwell Science, Malden, Massachusetts, USA
-
(1997)
Cells, embryos, and evolution: Toward a cellular and developmental understanding of phenotypic variation and evolutionary adaptability
-
-
Gerhart, J.1
Kirschner, M.2
-
15
-
-
1542619848
-
Cancer as a robust system: Implications for anticancer therapy
-
Kitano H (2004) Cancer as a robust system: implications for anticancer therapy. Nat Rev Cancer 4(3): 227-235
-
(2004)
Nat Rev Cancer
, vol.4
, Issue.3
, pp. 227-235
-
-
Kitano, H.1
-
16
-
-
0344010691
-
Cancer robustness: Tumour tactics
-
Kitano H (2003) Cancer robustness: tumour tactics. Nature 426(6963): 125
-
(2003)
Nature
, vol.426
, Issue.6963
, pp. 125
-
-
Kitano, H.1
-
17
-
-
7644241654
-
Metabolic syndrome and robustness tradeoffs
-
Kitano H, Oda K, Kimura T, Matsuoka Y, Csete M, Doyle J, Muramatsu M (2004) Metabolic syndrome and robustness tradeoffs. Diabetes 53 Suppl 3: S6-S15
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Kitano, H.1
Oda, K.2
Kimura, T.3
Matsuoka, Y.4
Csete, M.5
Doyle, J.6
Muramatsu, M.7
-
19
-
-
0036532226
-
Self-perpetuating states in signal transduction: Positive feedback, double-negative feedback and bistability
-
Ferrell JE Jr (2002) Self-perpetuating states in signal transduction: positive feedback, double-negative feedback and bistability. Curr Opin Cell Biol 14(2): 140-148
-
(2002)
Curr Opin Cell Biol
, vol.14
, Issue.2
, pp. 140-148
-
-
Ferrell Jr, J.E.1
-
20
-
-
3343020085
-
Integrative analysis of cell cycle control in budding yeast
-
Chen KC, Calzone L, Csikasz-Nagy A, Cross FR, Novak B, Tyson JJ (2004) Integrative analysis of cell cycle control in budding yeast. Mol Biol Cell 15(8): 3841-3862
-
(2004)
Mol Biol Cell
, vol.15
, Issue.8
, pp. 3841-3862
-
-
Chen, K.C.1
Calzone, L.2
Csikasz-Nagy, A.3
Cross, F.R.4
Novak, B.5
Tyson, J.J.6
-
21
-
-
0035850895
-
Phenotypic plasticity in the interactions and evolution of species
-
Agrawal AA (2001) Phenotypic plasticity in the interactions and evolution of species. Science 294(5541): 321-326
-
(2001)
Science
, vol.294
, Issue.5541
, pp. 321-326
-
-
Agrawal, A.A.1
-
22
-
-
0003636712
-
-
Sinauer Associates, Inc, Sunderland, MA, USA
-
Schlichting C, Pigliucci M (1998) Phenotypic evolution: a reaction norm perspective. Sinauer Associates, Inc., Sunderland, MA, USA
-
(1998)
Phenotypic evolution: A reaction norm perspective
-
-
Schlichting, C.1
Pigliucci, M.2
-
23
-
-
0037136555
-
Robustness of the BMP morphogen gradient in Drosophila embryonic patterning
-
Eldar A, Dorfman R, Weiss D, Ashe H, Shilo BZ, Barkai N (2002) Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature 419(6904): 304-308
-
(2002)
Nature
, vol.419
, Issue.6904
, pp. 304-308
-
-
Eldar, A.1
Dorfman, R.2
Weiss, D.3
Ashe, H.4
Shilo, B.Z.5
Barkai, N.6
-
24
-
-
0037076210
-
Robustness, flexibility, and the role of lateral inhibition in the neurogenic network
-
Meir E, von Dassow G, Munro E, Odell GM (2002) Robustness, flexibility, and the role of lateral inhibition in the neurogenic network. Curr Biol 12(10): 778-786
-
(2002)
Curr Biol
, vol.12
, Issue.10
, pp. 778-786
-
-
Meir, E.1
von Dassow, G.2
Munro, E.3
Odell, G.M.4
-
25
-
-
0004319914
-
-
Schlosser G, Wagner G eds, The University of Chicago Press, Chicago, USA
-
Schlosser G, Wagner G (eds) (2004) Modularity in development and evolution. The University of Chicago Press, Chicago, USA
-
(2004)
Modularity in development and evolution
-
-
-
26
-
-
0032569851
-
Hsp90 as a capacitor for morphological evolution
-
Rutherford SL, Lindquist S (1998) Hsp90 as a capacitor for morphological evolution. Nature 396(6709): 336-342
-
(1998)
Nature
, vol.396
, Issue.6709
, pp. 336-342
-
-
Rutherford, S.L.1
Lindquist, S.2
-
27
-
-
0037030713
-
Hsp90 as a capacitor of phenotypic variation
-
Queitsch C, Sangster TA, Lindquist S (2002) Hsp90 as a capacitor of phenotypic variation. Nature 417(6889): 618-624
-
(2002)
Nature
, vol.417
, Issue.6889
, pp. 618-624
-
-
Queitsch, C.1
Sangster, T.A.2
Lindquist, S.3
-
28
-
-
0036678862
-
Waddington's canalization revisited: Developmental stability and evolution
-
Siegal ML, Bergman A (2002) Waddington's canalization revisited: developmental stability and evolution. Proc Natl Acad Sci USA 99(16): 10528-10532
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.16
, pp. 10528-10532
-
-
Siegal, M.L.1
Bergman, A.2
-
30
-
-
0842332406
-
Dynamics of the p53-Mdm2 feedback loop in individual cells
-
Lahav G, Rosenfeld N, Sigal A, Geva-Zatorsky N, Levine AJ, Elowitz MB, Alon U (2004) Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat Genet 36(2): 147-150
-
(2004)
Nat Genet
, vol.36
, Issue.2
, pp. 147-150
-
-
Lahav, G.1
Rosenfeld, N.2
Sigal, A.3
Geva-Zatorsky, N.4
Levine, A.J.5
Elowitz, M.B.6
Alon, U.7
-
31
-
-
4344670936
-
Bow ties, metabolism and disease
-
Csete ME, Doyle J (2004) Bow ties, metabolism and disease. Trends Biotechnol 22(9): 446-450
-
(2004)
Trends Biotechnol
, vol.22
, Issue.9
, pp. 446-450
-
-
Csete, M.E.1
Doyle, J.2
-
33
-
-
0037133146
-
Complexity and robustness
-
Carlson JM, Doyle J (2002) Complexity and robustness. Proc Natl Acad Sci USA 99 Suppl 1: 2538-2545
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.SUPPL. 1
, pp. 2538-2545
-
-
Carlson, J.M.1
Doyle, J.2
-
34
-
-
0036500834
-
Reverse engineering of biological complexity
-
Csete ME, Doyle JC (2002) Reverse engineering of biological complexity. Science 295(5560): 1664-1669
-
(2002)
Science
, vol.295
, Issue.5560
, pp. 1664-1669
-
-
Csete, M.E.1
Doyle, J.C.2
-
36
-
-
0742305866
-
Network biology: Understanding the cell's functional organization
-
Barabasi AL, Oltvai ZN (2004) Network biology: understanding the cell's functional organization. Nat Rev Genet 5(2): 101-113
-
(2004)
Nat Rev Genet
, vol.5
, Issue.2
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
38
-
-
13244256806
-
Escape of intracellular Shigella from autophagy
-
Ogawa M, Yoshimori T, Suzuki T, Sagara H, Mizushima N, Sasakawa C (2005) Escape of intracellular Shigella from autophagy. Science 307(5710): 727-731
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 727-731
-
-
Ogawa, M.1
Yoshimori, T.2
Suzuki, T.3
Sagara, H.4
Mizushima, N.5
Sasakawa, C.6
-
39
-
-
0033515032
-
The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
-
Hersh D, Monack DM, Smith MR, Ghori N, Falkow S, Zychlinsky A (1999) The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc Natl Acad Sci USA 96(5): 2396-2401
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.5
, pp. 2396-2401
-
-
Hersh, D.1
Monack, D.M.2
Smith, M.R.3
Ghori, N.4
Falkow, S.5
Zychlinsky, A.6
-
40
-
-
0042195926
-
Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system
-
Waterman SR, Holden DW (2003) Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system. Cell Microbiol 5(8): 501-511
-
(2003)
Cell Microbiol
, vol.5
, Issue.8
, pp. 501-511
-
-
Waterman, S.R.1
Holden, D.W.2
-
41
-
-
0037213412
-
Invasion of mammalian cells by Listeria monocytogenes: Functional mimicry to subvert cellular functions
-
Cossart P, Pizarro-Cerda J, Lecuit M (2003) Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions. Trends Cell Biol 13(1): 23-31
-
(2003)
Trends Cell Biol
, vol.13
, Issue.1
, pp. 23-31
-
-
Cossart, P.1
Pizarro-Cerda, J.2
Lecuit, M.3
-
42
-
-
0033758756
-
Pathogenicity islands and the evolution of microbes
-
Hacker J, Kaper JB (2000) Pathogenicity islands and the evolution of microbes. Annu Rev Microbiol 54: 641-679
-
(2000)
Annu Rev Microbiol
, vol.54
, pp. 641-679
-
-
Hacker, J.1
Kaper, J.B.2
-
43
-
-
0030606233
-
Pathogenicity islands: Bacterial evolution in quantum leaps
-
Groisman EA, Ochman H (1996) Pathogenicity islands: bacterial evolution in quantum leaps. Cell 87(5): 791-794
-
(1996)
Cell
, vol.87
, Issue.5
, pp. 791-794
-
-
Groisman, E.A.1
Ochman, H.2
-
44
-
-
0030057090
-
Lysogenic conversion by a filamentous phage encoding cholera toxin
-
Waldor MK, Mekalanos JJ (1996) Lysogenic conversion by a filamentous phage encoding cholera toxin. Science 272(5270): 1910-1914
-
(1996)
Science
, vol.272
, Issue.5270
, pp. 1910-1914
-
-
Waldor, M.K.1
Mekalanos, J.J.2
-
45
-
-
3142544236
-
Frontal and stealth attack strategies in microbial pathogenesis
-
Merrell DS, Falkow S (2004) Frontal and stealth attack strategies in microbial pathogenesis. Nature 430(6996): 250-256
-
(2004)
Nature
, vol.430
, Issue.6996
, pp. 250-256
-
-
Merrell, D.S.1
Falkow, S.2
-
46
-
-
17644405864
-
Trypanosomes expressing a mosaic variant surface glycoprotein coat escape early detection by the immune system
-
Dubois ME, Demick KP, Mansfield JM (2005) Trypanosomes expressing a mosaic variant surface glycoprotein coat escape early detection by the immune system. Infect Immun 73(5): 2690-2697
-
(2005)
Infect Immun
, vol.73
, Issue.5
, pp. 2690-2697
-
-
Dubois, M.E.1
Demick, K.P.2
Mansfield, J.M.3
-
47
-
-
13244290294
-
An endangered species in the stomach
-
Blaser MJ (2005) An endangered species in the stomach. Sci Am 292(2): 38-45
-
(2005)
Sci Am
, vol.292
, Issue.2
, pp. 38-45
-
-
Blaser, M.J.1
-
48
-
-
0344010681
-
Effects of Helicobacter pylori CagA protein on the growth and survival of B lymphocytes, the origin of MALT lymphoma
-
Umehara S, Higashi H, Ohnishi N, Asaka M, Hatakeyama M (2003) Effects of Helicobacter pylori CagA protein on the growth and survival of B lymphocytes, the origin of MALT lymphoma. Oncogene 22(51): 8337-8342
-
(2003)
Oncogene
, vol.22
, Issue.51
, pp. 8337-8342
-
-
Umehara, S.1
Higashi, H.2
Ohnishi, N.3
Asaka, M.4
Hatakeyama, M.5
-
49
-
-
0035912232
-
The dynamics of CD4+ T-cell depletion in HIV disease
-
McCune JM (2001) The dynamics of CD4+ T-cell depletion in HIV disease. Nature 410(6831): 974-979
-
(2001)
Nature
, vol.410
, Issue.6831
, pp. 974-979
-
-
McCune, J.M.1
-
50
-
-
0035912222
-
Cellular immune responses to HIV
-
McMichael AJ, Rowland-Jones SL (2001) Cellular immune responses to HIV. Nature 410(6831): 980-987
-
(2001)
Nature
, vol.410
, Issue.6831
, pp. 980-987
-
-
McMichael, A.J.1
Rowland-Jones, S.L.2
-
51
-
-
0024310253
-
Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
-
Larder BA, Kemp SD (1989) Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 246(4934): 1155-1158
-
(1989)
Science
, vol.246
, Issue.4934
, pp. 1155-1158
-
-
Larder, B.A.1
Kemp, S.D.2
-
52
-
-
0027285372
-
Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase
-
Tisdale M, Kemp SD, Parry NR, Larder BA (1993) Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3′-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase. Proc Natl Acad Sci USA 90(12): 5653-5656
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.12
, pp. 5653-5656
-
-
Tisdale, M.1
Kemp, S.D.2
Parry, N.R.3
Larder, B.A.4
-
53
-
-
0029028067
-
Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy
-
Larder BA, Kemp SD, Harrigan PR (1995) Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy. Science 269(5224): 696-699
-
(1995)
Science
, vol.269
, Issue.5224
, pp. 696-699
-
-
Larder, B.A.1
Kemp, S.D.2
Harrigan, P.R.3
-
54
-
-
0029764099
-
A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread
-
Dropulic B, Hermankova M, Pitha PM (1996) A conditionally replicating HIV-1 vector interferes with wild-type HIV-1 replication and spread. Proc Natl Acad Sci USA 93(20): 11103-11108
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.20
, pp. 11103-11108
-
-
Dropulic, B.1
Hermankova, M.2
Pitha, P.M.3
-
55
-
-
0141570489
-
Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection
-
Weinberger LS, Schaffer DV, Arkin AP (2003) Theoretical design of a gene therapy to prevent AIDS but not human immunodeficiency virus type 1 infection. J Virol 77(18): 10028-10036
-
(2003)
J Virol
, vol.77
, Issue.18
, pp. 10028-10036
-
-
Weinberger, L.S.1
Schaffer, D.V.2
Arkin, A.P.3
-
56
-
-
0036165770
-
Gene therapy of HIV-1 infection using lentiviral vectors expressing anti-HIV-1 genes
-
Mautino MR, Morgan RA (2002) Gene therapy of HIV-1 infection using lentiviral vectors expressing anti-HIV-1 genes. AIDS Patient Care STDS 16(1): 11-26
-
(2002)
AIDS Patient Care STDS
, vol.16
, Issue.1
, pp. 11-26
-
-
Mautino, M.R.1
Morgan, R.A.2
-
57
-
-
33745470929
-
-
Kitano H, Oda K (2006) Robustness trade-offs and host-microbial symbiosis in the immune system. Mol Sys Biol msb4100039-E1
-
Kitano H, Oda K (2006) Robustness trade-offs and host-microbial symbiosis in the immune system. Mol Sys Biol msb4100039-E1
-
-
-
-
58
-
-
33745463739
-
-
Oda K, Kitano H (2006) A comprehensive molecular interaction map of Toll-like receptor signaling network. Mol Sys Biol msb4100057
-
Oda K, Kitano H (2006) A comprehensive molecular interaction map of Toll-like receptor signaling network. Mol Sys Biol msb4100057
-
-
-
-
59
-
-
2442445450
-
Inflammatory resolution: New opportunities for drug discovery
-
Gilroy DW, Lawrence T, Perretti M, Rossi AG (2004) Inflammatory resolution: new opportunities for drug discovery. Nat Rev Drug Discov 3(5): 401-416
-
(2004)
Nat Rev Drug Discov
, vol.3
, Issue.5
, pp. 401-416
-
-
Gilroy, D.W.1
Lawrence, T.2
Perretti, M.3
Rossi, A.G.4
-
60
-
-
0037180812
-
Points of control in inflammation
-
Nathan C (2002) Points of control in inflammation. Nature 420(6917): 846-852
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 846-852
-
-
Nathan, C.1
-
62
-
-
0028833049
-
Cytokines and the acute phase response to influenza virus in mice
-
Conn CA, McClellan JL, Maassab HF, Smitka CW, Majde JA, Kluger MJ (1995) Cytokines and the acute phase response to influenza virus in mice. Am J Physiol 268(1 Pt 2): R78-84
-
(1995)
Am J Physiol
, vol.268
, Issue.1 PART 2
-
-
Conn, C.A.1
McClellan, J.L.2
Maassab, H.F.3
Smitka, C.W.4
Majde, J.A.5
Kluger, M.J.6
-
63
-
-
0026703488
-
A kinetic study of immune mediators in the lungs ofmice infected with influenza A virus
-
Hennet T, Ziltener HJ, Frei K, Peterhans E (1992) A kinetic study of immune mediators in the lungs ofmice infected with influenza A virus. J Immunol 149(3): 932-939
-
(1992)
J Immunol
, vol.149
, Issue.3
, pp. 932-939
-
-
Hennet, T.1
Ziltener, H.J.2
Frei, K.3
Peterhans, E.4
-
64
-
-
0020376586
-
Interferon production by leukocytes infiltrating the lungs of mice during primary influenza virus infection
-
Wyde PR, Wilson MR, Cate TR (1982) Interferon production by leukocytes infiltrating the lungs of mice during primary influenza virus infection. Infect Immun 38(3): 1249-1255
-
(1982)
Infect Immun
, vol.38
, Issue.3
, pp. 1249-1255
-
-
Wyde, P.R.1
Wilson, M.R.2
Cate, T.R.3
-
65
-
-
0024375781
-
Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD
-
Oda T, Akaike T, Hamamoto T, Suzuki F, Hirano T, Maeda H (1989) Oxygen radicals in influenza-induced pathogenesis and treatment with pyran polymer-conjugated SOD. Science 244(4907): 974-976
-
(1989)
Science
, vol.244
, Issue.4907
, pp. 974-976
-
-
Oda, T.1
Akaike, T.2
Hamamoto, T.3
Suzuki, F.4
Hirano, T.5
Maeda, H.6
-
66
-
-
0029094921
-
Small amounts of exogenous IL-4 increase the severity of encephalitis induced in mice by the intranasal infection of herpes simplex virus type 1
-
Ikemoto K, Pollard RB, Fukumoto T, Morimatsu M, Suzuki F (1995) Small amounts of exogenous IL-4 increase the severity of encephalitis induced in mice by the intranasal infection of herpes simplex virus type 1. J Immunol 155(3): 1326-1333
-
(1995)
J Immunol
, vol.155
, Issue.3
, pp. 1326-1333
-
-
Ikemoto, K.1
Pollard, R.B.2
Fukumoto, T.3
Morimatsu, M.4
Suzuki, F.5
-
67
-
-
0028267312
-
Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated human blood from patients with heart failure
-
Matsumori A, Shioi T, Yamada T, Matsui S, Sasayama S (1994) Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated human blood from patients with heart failure. Circulation 89(3): 955-958
-
(1994)
Circulation
, vol.89
, Issue.3
, pp. 955-958
-
-
Matsumori, A.1
Shioi, T.2
Yamada, T.3
Matsui, S.4
Sasayama, S.5
-
68
-
-
0028106793
-
Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production
-
Matsui S, Matsumori A, Matoba Y, Uchida A, Sasayama S (1994) Treatment of virus-induced myocardial injury with a novel immunomodulating agent, vesnarinone. Suppression of natural killer cell activity and tumor necrosis factor-alpha production. J Clin Invest 94(3): 1212-1217
-
(1994)
J Clin Invest
, vol.94
, Issue.3
, pp. 1212-1217
-
-
Matsui, S.1
Matsumori, A.2
Matoba, Y.3
Uchida, A.4
Sasayama, S.5
-
69
-
-
0023903858
-
Enhanced tumour necrosis factor and interleukin-1 in fulminant hepatic failure
-
Muto Y, Nouri-Aria KT, Meager A, Alexander GJ, Eddleston AL, Williams R (1988) Enhanced tumour necrosis factor and interleukin-1 in fulminant hepatic failure. Lancet 2(8602): 72-74
-
(1988)
Lancet
, vol.2
, Issue.8602
, pp. 72-74
-
-
Muto, Y.1
Nouri-Aria, K.T.2
Meager, A.3
Alexander, G.J.4
Eddleston, A.L.5
Williams, R.6
-
70
-
-
0025852720
-
A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits
-
Wakabayashi G, Gelfand JA, Burke JF, Thompson RC, Dinarello CA (1991) A specific receptor antagonist for interleukin 1 prevents Escherichia coli-induced shock in rabbits. Faseb J 5(3): 338-343
-
(1991)
Faseb J
, vol.5
, Issue.3
, pp. 338-343
-
-
Wakabayashi, G.1
Gelfand, J.A.2
Burke, J.F.3
Thompson, R.C.4
Dinarello, C.A.5
-
71
-
-
4344670936
-
Bow ties, metabolism and disease
-
Csete M, Doyle J (2004) Bow ties, metabolism and disease. Trends Biotechnol 22(9): 446-450
-
(2004)
Trends Biotechnol
, vol.22
, Issue.9
, pp. 446-450
-
-
Csete, M.1
Doyle, J.2
-
72
-
-
0026042333
-
Sequence analysis of peptides bound to MHC class II molecules
-
Rudensky A, Preston-Hurlburt P, Hong SC, Barlow A, Janeway CA Jr (1991) Sequence analysis of peptides bound to MHC class II molecules. Nature 353(6345): 622-627
-
(1991)
Nature
, vol.353
, Issue.6345
, pp. 622-627
-
-
Rudensky, A.1
Preston-Hurlburt, P.2
Hong, S.C.3
Barlow, A.4
Janeway Jr, C.A.5
-
73
-
-
0027217789
-
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1
-
Brown JH, Jardetzky TS, Gorga JC, Stern LJ, Urban RG, Strominger JL, Wiley DC (1993) Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1. Nature 364(6432): 33-39
-
(1993)
Nature
, vol.364
, Issue.6432
, pp. 33-39
-
-
Brown, J.H.1
Jardetzky, T.S.2
Gorga, J.C.3
Stern, L.J.4
Urban, R.G.5
Strominger, J.L.6
Wiley, D.C.7
-
74
-
-
0035142615
-
Cut and trim: Generating MHC class I peptide ligands
-
Yewdell JW, Bennink JR (2001) Cut and trim: generating MHC class I peptide ligands. Curr Opin Immunol 13(1): 13-18
-
(2001)
Curr Opin Immunol
, vol.13
, Issue.1
, pp. 13-18
-
-
Yewdell, J.W.1
Bennink, J.R.2
-
75
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing
-
Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M (2005) Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science 307(5710): 734-738
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
76
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nunez G, Flavell RA (2005) Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 307(5710): 731-734
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
77
-
-
0032798049
-
Presence of eubacteria in biopsies from Crohn's disease inflammatory lesions as determined by 16S rRNA gene-based PCR
-
Tiveljung A, Soderholm JD, Olaison G, Jonasson J, Monstein HJ (1999) Presence of eubacteria in biopsies from Crohn's disease inflammatory lesions as determined by 16S rRNA gene-based PCR. J Med Microbiol 48(3): 263-268
-
(1999)
J Med Microbiol
, vol.48
, Issue.3
, pp. 263-268
-
-
Tiveljung, A.1
Soderholm, J.D.2
Olaison, G.3
Jonasson, J.4
Monstein, H.J.5
-
78
-
-
0030021722
-
Molecular mimicry in the MHC: Hidden clues to autoimmunity?
-
Baum H, Davies H, Peakman M (1996) Molecular mimicry in the MHC: hidden clues to autoimmunity? Immunol Today 17(2): 64-70
-
(1996)
Immunol Today
, vol.17
, Issue.2
, pp. 64-70
-
-
Baum, H.1
Davies, H.2
Peakman, M.3
-
79
-
-
10744228908
-
Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity
-
Eriksson U, Ricci R, Hunziker L, Kurrer MO, Oudit GY, Watts TH, Sonderegger I, Bachmaier K, Kopf M, Penninger JM (2003) Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Nat Med 9(12): 1484-1490
-
(2003)
Nat Med
, vol.9
, Issue.12
, pp. 1484-1490
-
-
Eriksson, U.1
Ricci, R.2
Hunziker, L.3
Kurrer, M.O.4
Oudit, G.Y.5
Watts, T.H.6
Sonderegger, I.7
Bachmaier, K.8
Kopf, M.9
Penninger, J.M.10
-
80
-
-
1842613450
-
Microorganisms and autoimmunity: Making the barren field fertile?
-
von Herrath MG, Fujinami RS, Whitton JL (2003) Microorganisms and autoimmunity: making the barren field fertile? Nat Rev Microbiol 1(2): 151-157
-
(2003)
Nat Rev Microbiol
, vol.1
, Issue.2
, pp. 151-157
-
-
von Herrath, M.G.1
Fujinami, R.S.2
Whitton, J.L.3
-
81
-
-
0023770125
-
Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction
-
Saikku P, Leinonen M, Mattila K, Ekman MR, Nieminen MS, Makela PH, Huttunen JK, Valtonen V (1988) Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction. Lancet 2(8618): 983-986
-
(1988)
Lancet
, vol.2
, Issue.8618
, pp. 983-986
-
-
Saikku, P.1
Leinonen, M.2
Mattila, K.3
Ekman, M.R.4
Nieminen, M.S.5
Makela, P.H.6
Huttunen, J.K.7
Valtonen, V.8
-
82
-
-
1842486666
-
Chlamydia pneumoniae - an infectious risk factor for atherosclerosis?
-
Campbell LA, Kuo CC (2004) Chlamydia pneumoniae - an infectious risk factor for atherosclerosis? Nat Rev Microbiol 2(1): 23-32
-
(2004)
Nat Rev Microbiol
, vol.2
, Issue.1
, pp. 23-32
-
-
Campbell, L.A.1
Kuo, C.C.2
-
83
-
-
0035189431
-
Chlamydia pneumoniae infects and multiplies in lymphocytes in vitro
-
Haranaga S, Yamaguchi H, Friedman H, Izumi S, Yamamoto Y (2001) Chlamydia pneumoniae infects and multiplies in lymphocytes in vitro. Infect Immun 69(12): 7753-7759
-
(2001)
Infect Immun
, vol.69
, Issue.12
, pp. 7753-7759
-
-
Haranaga, S.1
Yamaguchi, H.2
Friedman, H.3
Izumi, S.4
Yamamoto, Y.5
-
84
-
-
0032694362
-
Autoimmunity and atherosclerosis
-
Wick G, Perschinka H, Xu Q (1999) Autoimmunity and atherosclerosis. Am Heart J 138(5 Pt 2): S444-449
-
(1999)
Am Heart J
, vol.138
, Issue.5 PART 2
-
-
Wick, G.1
Perschinka, H.2
Xu, Q.3
-
85
-
-
0033605250
-
Chlamydia infections and heart disease linked through antigenic mimicry
-
Bachmaier K, Neu N, de la Maza LM, Pal S, Hessel A, Penninger JM (1999) Chlamydia infections and heart disease linked through antigenic mimicry. Science 283(5406): 1335-1339
-
(1999)
Science
, vol.283
, Issue.5406
, pp. 1335-1339
-
-
Bachmaier, K.1
Neu, N.2
de la Maza, L.M.3
Pal, S.4
Hessel, A.5
Penninger, J.M.6
-
86
-
-
0142026205
-
Inaugural article: Honor thy symbionts
-
Xu J, Gordon JI (2003) Inaugural article: Honor thy symbionts. Proc Natl Acad Sci USA 100(18): 10452-10459
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.18
, pp. 10452-10459
-
-
Xu, J.1
Gordon, J.I.2
-
87
-
-
0017341656
-
Microbial ecology of the gastrointestinal tract
-
Savage DC (1977) Microbial ecology of the gastrointestinal tract. Annu Rev Microbiol 31: 107-133
-
(1977)
Annu Rev Microbiol
, vol.31
, pp. 107-133
-
-
Savage, D.C.1
-
88
-
-
0036399823
-
How host-microbial interactions shape the nutrient environment of the mammalian intestine
-
Hooper LV, Midtvedt T, Gordon JI (2002) How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annu Rev Nutr 22: 283-307
-
(2002)
Annu Rev Nutr
, vol.22
, pp. 283-307
-
-
Hooper, L.V.1
Midtvedt, T.2
Gordon, J.I.3
-
89
-
-
0034802944
-
IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms
-
Macpherson AJ, Hunziker L, McCoy K, Lamarre A (2001) IgA responses in the intestinal mucosa against pathogenic and non-pathogenic microorganisms. Microbes Infect 3(12): 1021-1035
-
(2001)
Microbes Infect
, vol.3
, Issue.12
, pp. 1021-1035
-
-
Macpherson, A.J.1
Hunziker, L.2
McCoy, K.3
Lamarre, A.4
-
90
-
-
0036971220
-
The functions of mucosal T cells in containing the indigenous commensal flora of the intestine
-
Macpherson AJ, Martinic MM, Harris N (2002) The functions of mucosal T cells in containing the indigenous commensal flora of the intestine. Cell Mol Life Sci 59(12): 2088-2096
-
(2002)
Cell Mol Life Sci
, vol.59
, Issue.12
, pp. 2088-2096
-
-
Macpherson, A.J.1
Martinic, M.M.2
Harris, N.3
-
91
-
-
0037180433
-
Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells
-
Stappenbeck TS, Hooper LV, Gordon JI (2002) Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci USA 99(24): 15451-15455
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.24
, pp. 15451-15455
-
-
Stappenbeck, T.S.1
Hooper, L.V.2
Gordon, J.I.3
-
92
-
-
36448981211
-
Self-extending symbiosis: A mechanism for increasing robustness through evolution
-
Kitano H, Oda K (2006) Self-extending symbiosis: a mechanism for increasing robustness through evolution. Biological Theory 1(1): 61-66
-
(2006)
Biological Theory
, vol.1
, Issue.1
, pp. 61-66
-
-
Kitano, H.1
Oda, K.2
-
93
-
-
0023722797
-
Factors influencing potent antagonistic effects of Escherichia coli and Bacteroides ovatus on Staphylococcus aureus in anaerobic continuous flow cultures
-
Ushijima T, Ozaki Y (1988) Factors influencing potent antagonistic effects of Escherichia coli and Bacteroides ovatus on Staphylococcus aureus in anaerobic continuous flow cultures. Can J Microbiol 34(5): 645-650
-
(1988)
Can J Microbiol
, vol.34
, Issue.5
, pp. 645-650
-
-
Ushijima, T.1
Ozaki, Y.2
-
94
-
-
0022497936
-
Potent antagonism of Escherichia coli, Bacteroides ovatus, Fusobacterium varium, and Enterococcus faecalis, alone or in combination, for enteropathogens in anaerobic continuous flow cultures
-
Ushijima T, Ozaki Y (1986) Potent antagonism of Escherichia coli, Bacteroides ovatus, Fusobacterium varium, and Enterococcus faecalis, alone or in combination, for enteropathogens in anaerobic continuous flow cultures. J Med Microbiol 22(2): 157-163
-
(1986)
J Med Microbiol
, vol.22
, Issue.2
, pp. 157-163
-
-
Ushijima, T.1
Ozaki, Y.2
-
95
-
-
0034831139
-
Probiotic bacteria enhance murine and human intestinal epithelial barrier function
-
Madsen K, Cornish A, Soper P, McKaigney C, Jijon H, Yachimec C, Doyle J, Jewell L, De Simone C (2001) Probiotic bacteria enhance murine and human intestinal epithelial barrier function. Gastroenterology 121(3): 580-591
-
(2001)
Gastroenterology
, vol.121
, Issue.3
, pp. 580-591
-
-
Madsen, K.1
Cornish, A.2
Soper, P.3
McKaigney, C.4
Jijon, H.5
Yachimec, C.6
Doyle, J.7
Jewell, L.8
De Simone, C.9
-
96
-
-
13244275284
-
Probiotic therapy of intestinal inflammation and infections
-
Sartor RB (2005) Probiotic therapy of intestinal inflammation and infections. Curr Opin Gastroenterol 21(1): 44-50
-
(2005)
Curr Opin Gastroenterol
, vol.21
, Issue.1
, pp. 44-50
-
-
Sartor, R.B.1
-
97
-
-
0033675729
-
Treatment and prevention of antibiotic associated diarrhea
-
Bergogne-Berezin E (2000) Treatment and prevention of antibiotic associated diarrhea. Int J Antimicrob Agents 16(4): 521-526
-
(2000)
Int J Antimicrob Agents
, vol.16
, Issue.4
, pp. 521-526
-
-
Bergogne-Berezin, E.1
-
98
-
-
0037165170
-
Species diversity enhances ecosystem functioning through interspecific facilitation
-
Cardinale BJ, Palmer MA, Collins SL (2002) Species diversity enhances ecosystem functioning through interspecific facilitation. Nature 415(6870): 426-429
-
(2002)
Nature
, vol.415
, Issue.6870
, pp. 426-429
-
-
Cardinale, B.J.1
Palmer, M.A.2
Collins, S.L.3
-
99
-
-
2342644671
-
Microbial astronauts: Assembling microbial communities for advanced life support systems
-
Roberts MS, Garland JL, Mills AL (2004) Microbial astronauts: assembling microbial communities for advanced life support systems. Microb Ecol 47(2): 137-149
-
(2004)
Microb Ecol
, vol.47
, Issue.2
, pp. 137-149
-
-
Roberts, M.S.1
Garland, J.L.2
Mills, A.L.3
-
100
-
-
2342442430
-
Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
-
Ott SJ, Musfeldt M, Wenderoth DF, Hampe J, Brant O, Folsch UR, Timmis KN, Schreiber S (2004) Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut 53(5): 685-693
-
(2004)
Gut
, vol.53
, Issue.5
, pp. 685-693
-
-
Ott, S.J.1
Musfeldt, M.2
Wenderoth, D.F.3
Hampe, J.4
Brant, O.5
Folsch, U.R.6
Timmis, K.N.7
Schreiber, S.8
-
101
-
-
0038337828
-
Targeting enteric bacteria in treatment of inflammatory bowel diseases: Why, how, and when
-
Sartor RB (2003) Targeting enteric bacteria in treatment of inflammatory bowel diseases: why, how, and when. Curr Opin Gastroenterol 19(4): 358-365
-
(2003)
Curr Opin Gastroenterol
, vol.19
, Issue.4
, pp. 358-365
-
-
Sartor, R.B.1
-
102
-
-
0036140777
-
Mucosal flora in inflammatory bowel disease
-
Swidsinski A, Ladhoff A, Pernthaler A, Swidsinski S, Loening-Baucke V, Ortner M, Weber J, Hoffmann U, Schreiber S, Dietel M et al (2002) Mucosal flora in inflammatory bowel disease. Gastroenterology 122(1): 44-54
-
(2002)
Gastroenterology
, vol.122
, Issue.1
, pp. 44-54
-
-
Swidsinski, A.1
Ladhoff, A.2
Pernthaler, A.3
Swidsinski, S.4
Loening-Baucke, V.5
Ortner, M.6
Weber, J.7
Hoffmann, U.8
Schreiber, S.9
Dietel, M.10
-
103
-
-
15544369658
-
Host-bacterial mutualism in the human intestine
-
Backhed F, Ley R, Sonnenburg J, Peterson D, Gordon JI (2005) Host-bacterial mutualism in the human intestine. Science 307: 1915-1920
-
(2005)
Science
, vol.307
, pp. 1915-1920
-
-
Backhed, F.1
Ley, R.2
Sonnenburg, J.3
Peterson, D.4
Gordon, J.I.5
|