Pathogenicity islands and the evolution of microbes

Annual Review of Microbiology

Volumn 54, Issue , 2000, Pages 641-679

  Hacker, J ^a   Kaper, J B ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Bacteriophage; Gene transfer; Genome structure; Plasmid; Virulence

Indexed keywords

ADHESIN; BACTERIAL TOXIN; INTEGRASE; INVASIN; TRANSFER RNA; VIRULENCE FACTOR;

BACTERIAL VIRULENCE; BACTERIOPHAGE; ESCHERICHIA COLI; EVOLUTION; GENE LOCUS; GENE STRUCTURE; GENE TRANSFER; GENETIC STABILITY; IRON TRANSPORT; NONHUMAN; PATHOGENICITY; PLASMID; PRIORITY JOURNAL; REVIEW;

BACTERIA; BASE SEQUENCE; DNA, BACTERIAL; EVOLUTION; GENES, BACTERIAL; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, TRANSFER; VIRULENCE;

EID: 0033758756     PISSN: 00664227     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.micro.54.1.641     Document Type: Review

References (120)

1. Serotype 1a O-antigen modification: Molecular characterization of the genes involved and their novel organization in the Shigella flexneri chromosome
2. A mRNA signal for the type III secretion of Yop proteins by Yersinia enterocolitica
3. The tripartite type HI secreton of Shigella flexneri inserts IpaB and IpaC into host membranes
4. Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen
5. Binding of the shigella protein IpaA to vinculin induces F-acfin depolymerization
6. Molecular characterization of an antibiotic resistance gene cluster of Salmonella typhimurium DT104
7. The high-pathogenicity island of Yersinia pseudotuberculosis can be inserted into any of the three chromosomal asn tRNA genes
8. The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O 157:H7
9. Biochemistry of type IV secretion
10. Cag, a pathogenicity island of Helicobacter pylori, encodes type-I specific and disease-associated virulence factors
11. A role for bacteriophages in the evolution and transfer of bacterial virulence determinants
12. Reduced polysialic acid capsule expression in Escherichia coli K1 mutants with chromosomal defects in kpsF
13. Bacterial attachment to uroepithelial cells: Mechanisms and consequences
14. The virulence plasmid of Yersinia, an antihost genome
15. The Yersinia Yop virulon: A bacterial system for subverting eukaryotic cells
16. In vivo and ex vivo regulation of bacterial virulence gene expression
17. InvF is required for expression of genes encoding proteins secreted by the SPI1 type III secretion apparatus in Salmonella typhimurium
18. Co-ordinate expression of virulence genes by ToxR in Vibrio cholerae
19. Plasmids, phages and pathogenicity islands: Lessons on the evolution of bacterial toxins
20. Identification of CesTa chaperone for the type III secretion of Tir in enteropathogenic Escherichia coli
21. The cloned locus of enterocyte effacement from enterohemorrhagic Escherichia coli O157:H7 is unable to confer the attaching and effacing phenotype upon E. coli K-12
22. Shigella enterotoxin 1: An enterotoxin of Shigella flexneri 2a active in rabbit small intestine in vivo and in vitro
23. The cryptic general secretory pathway (gsp) operon of Escherichia coli K-12 encodes functional proteins
24. Molecular evolution of the pathogenicity island of enterotoxigenic Bacteroides fragilis strains
25. Enteropathogenic and enterohaemorrhagic Escherichia coli: More subversive elements
26. A salmonella protein antagonizes Rac-1 and Cdc42 to mediate host-cell recovery after bacterial invasion
27. Interaction of Salmonella with host cells through the centisome 63 type III secretion system
28. Type III secretion machines: Bacterial devices for protein delivery into host cells
29. Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vivo and in vitro in various extraintestinal Escherichia coli isolates
30. Pathogenicity islands of virulent bacteria: Structure, function and impact on microbial evolution
31. Spontaneous deletions and flanking regions of the chromosomal inherited hemolysin determinant of an Escherichia coli O6 strain
32. A chromosomally-encoded type III secretion apparatus of Yersinia enterocolitica affects virulence in the mouse model of infection
33. TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae
34. Characterization of Pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli
35. The great escape: Structure and function of the autotransporter proteins
36. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1
37. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB
38. Transfer RNAs and pathogenicity islands
39. Type III protein secretion systems in bacterial pathogens of animals and plants
40. The 70-kilobase virulence plasmid of Yersiniae
41. Cloning and nucleotide sequence determination of the entire mec DNA of pre-Methicillin-resistant Staphylococcus aureus N315
42. Identification of a pathogenicity island, which contains genes for virulence and avirulence, on a large native plasmid in the bean pathogen Pseudomonas syringae pathovar phaseolicola
43. Intimin-mediated adherence of Shiga toxin-producing Escherichia coli and attaching-and-effacing pathogens
44. Cholera
45. A Vibrio cholerae pathogenicity island associated with epidemic and pandemic strains
46. A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria
47. A genomic island, termed high-pathogenicity island, is present in certain non-O157 Shiga toxin-producing Escherichia coli clonal lineages
48. Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells
49. A novel EspA-associated surface organelle of enteropathogenic Escherichia coli involved in protein translocation into epithelial cells
50. A putative integrase gene defines the distal end of a large cluster of ToxR-regulated colonization genes in Vibrio cholerae
51. Supramolecular structure of the Salmonella typhimurium type III protein secretion system
52. Molecular archaeology of the Escherichia coli genome
53. The gene for toxic shock toxin is carried by a family of mobile pathogenicity islands in Staphylococcus aureus
54. Secretion of proteins and assembly of bacterial surface organelles: Shared pathways of extracellular protein targeting
55. Gene clusters governing the production of hemolysin and mannose-resistant hemagglutination are closely linked in Escherichia coli serotype O4 and O6 isolates from urinary tract infections
56. Genetic and transcriptional analyses of the Vibrio cholerae mannose-sensitive hemagglutinin type 4 pilus gene locus
57. A distinctive class of integron in the Vibrio cholerae genome
58. A genetic locus of enterocyte effacement conserved among diverse enterobacterial pathogens
59. A cloned pathogenicity island from enteropathogenic Escherichia coli confers the attaching and effacing phenotype on E. coli K-12
60. Spontaneous tandem amplification and deletion of the Shiga toxin operon in Shigella dysenteriae 1
61. The Per regulon of enteropathogenic Escherichia coli: Identification of a regulatory cascade and a novel transcriptional activator, the locus of enterocyte effacement (LEE)-encoded regulator (Ler)
62. Extracellular association and cytoplasmic partitioning of the IpaB and IpaC invasins of S. flexneri
63. The role of iron-binding proteins in the survival of pathogenic bacteria
64. Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type m secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein
65. Isolation of a temperate bacteriophage encoding the type III effector protein SopE from an epidemic Salmonella typhimurium strain
66. Yersiaia signals macrophages to undergo apoptosis and YopJ is necessary for this cell death
67. Evolution of microbial pathogens
68. Adhesin regulatory genes within large, unstable DNA regions of pathogenic Escherichia coli: Cross-talk between different adhesin gene clusters
69. The selC-associated SHI-2 pathogenicity island of Shigella flexneri
70. Diarrheagenic Escherichia coli
71. A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis
72. Molecular evolution of a pathogenicity island from enterohemorrhagic Escherichia coli O157:H7
73. Identification of regions of the chromosome of Neisseria meningitidis and Neisseria gonorrhoeae which are specific to the pathogenic Neisseria species
74. The complete general secretory pathway in gram-negative bacteria
75. Recent progress and future directions in studies of the main terminal branch of the general secretory pathway in gram-negative bacteria: A review
76. Use of a novel approach, termed island probing, identifies the Shigella flexneri she pathogenicity island which encodes a homolog of the immunoglobulin A protease-like family of proteins
77. The high-pathogenicity island of yersiniae
78. Transfer RNA genes frequently serve as integration sites for prokaryotic genetic elements
79. The PAI-associated leuX specific tRNA5(Leu) affects type 1 fimbriation in pathogenic Escherichia coli by control of FimB recombinase expression
80. Hrp pilus: An hrp-dependent bacterial surface appendage produced by Pseudomonas syringae pv. tomato DC3000
81. The Xanthomonas Hrp type III system secretes proteins from plant and mammalian bacterial pathogens
82. Two AraC/XylS family members can independently counteract the effect of repressing sequences upstream of the hilA promoter
83. Prevalence of the high-pathogenicity island of Yersinia species among Escherichia coli strains that are pathogenic to humans
84. Altered states: Involvement of phosphorylated CagA in the induction of host cellular growth changes by Helicobacter pylori
85. Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome
86. Relationships between a new type IV secretion system and the icm/dot virulence system of Legionella pneumophila
87. Cyclic AMP and its receptor protein negatively regulate the coordinate expression of cholera toxin and toxin-coregulated pilus in Vibrio cholerae
88. Cloning and sequencing of the genes downstream of the wbf gene cluster of Vibrio cholerae serogroup O139 and analysis of the junction genes in other serogroups
89. Quorum sensing controls expression of the type III secretion gene transcription and protein secretion in enterohemorrhagic and enteropathogenic Escherichia coli
90. Identification of a Salmonella virulence gene required for formation of filamentous structures containing lysosomal membrane glycoproteins within epithelial cells
91. Investigation of the roles of toxin-coregulated pili and mannose-sensitive hemagglutinin pill in the pathogenesis of Vibrio cholerae O139 infection
92. IpaC induces actin polymerization and filopodia formation during Shigella entry into epithelial cells
93. Mechanism of Shigella entry into epithelial cells
94. The Vibrio cholerae genome contains two unique circular chromosomes
95. A Salmonella virulence protein that inhibits cellular trafficking
96. Conjugative transfer by the virulence system of Legionella pneumophila
97. The aerobactin iron transport system genes in Shigella flexneri are present within a pathogenicity island
98. Insertion of EspD into epithelial target cell membranes by infecting enteropathogenic Escherichia coli
99. Lysogenic conversion by a filamentous phage encoding cholera toxin
100. A role for the mannose-sensitive hemagglutinin in biofilm formation by Vibrio cholerae El Tor
101. Customized secretion chaperones in pathogenic bacteria
102. Identification of a pathogenicity island required for Salmonella enteropathogenicity
103. Bacteroides fragilis enterotoxin cleaves the zonula adherens protein
104. Structure of the Shigella dysenteriae heaem transport locus and its phylogenetic distribution in enteric bacteria
105. Vibrio cholerae O1 El Tor: Identification of a gene cluster required for the rugose colony type, exopolysacchande production, chlorine resistance, and biofilm formation
106. A novel mechanism of phase variation of virulence in Staphylococcus epidermidis: Evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256