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Volumn 53, Issue SUPPL. 3, 2004, Pages

Metabolic syndrome and robustness tradeoffs

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN;

EID: 7644241654     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.53.suppl_3.S6     Document Type: Conference Paper
Times cited : (134)

References (70)
  • 1
    • 0037079054 scopus 로고    scopus 로고
    • Computational systems biology
    • Kitano H: Computational systems biology. Nature 420:206-210, 2002
    • (2002) Nature , vol.420 , pp. 206-210
    • Kitano, H.1
  • 2
    • 0036500993 scopus 로고    scopus 로고
    • Systems biology: A brief overview
    • Kitano H: Systems biology: a brief overview. Science 295:1662-1664, 2002
    • (2002) Science , vol.295 , pp. 1662-1664
    • Kitano, H.1
  • 4
    • 0030797355 scopus 로고    scopus 로고
    • Robustness in simple biochemical networks
    • Barkai N, Leibler S: Robustness in simple biochemical networks. Nature 387:913-917, 1997
    • (1997) Nature , vol.387 , pp. 913-917
    • Barkai, N.1    Leibler, S.2
  • 5
    • 0037136555 scopus 로고    scopus 로고
    • Robustness of the BMP morphogen gradient in Drosophila embryonic patterning
    • Eldar A, Dorfman R, Weiss D, Ashe H, Shilo BZ, Barkai N: Robustness of the BMP morphogen gradient in Drosophila embryonic patterning. Nature 419:304-308, 2002
    • (2002) Nature , vol.419 , pp. 304-308
    • Eldar, A.1    Dorfman, R.2    Weiss, D.3    Ashe, H.4    Shilo, B.Z.5    Barkai, N.6
  • 6
    • 0033517148 scopus 로고    scopus 로고
    • Robustness of a gene regulatory circuit
    • Little JW, Shepley DP, Wert DW: Robustness of a gene regulatory circuit. EMBO J 18:4299-4307, 1999
    • (1999) EMBO J , vol.18 , pp. 4299-4307
    • Little, J.W.1    Shepley, D.P.2    Wert, D.W.3
  • 7
    • 0033083733 scopus 로고    scopus 로고
    • It's a noisy business! Genetic regulation at the nanomolar scale
    • McAdams HH, Arkin A: It's a noisy business! Genetic regulation at the nanomolar scale. Trends Genet 15:65-69, 1999
    • (1999) Trends Genet , vol.15 , pp. 65-69
    • McAdams, H.H.1    Arkin, A.2
  • 8
    • 0037076210 scopus 로고    scopus 로고
    • Robustness, flexibility, and the role of lateral inhibition in the neurogenic network
    • Meir E, von Dassow G, Munro E, Odell GM: Robustness, flexibility, and the role of lateral inhibition in the neurogenic network. Curr Biol 12:778-786, 2002
    • (2002) Curr Biol , vol.12 , pp. 778-786
    • Meir, E.1    Von Dassow, G.2    Munro, E.3    Odell, G.M.4
  • 10
    • 0035927611 scopus 로고    scopus 로고
    • Robust oscillations within the interlocked feedback model of Drosophila circadian rhythm
    • Ueda HR, Hagiwara M, Kitano H: Robust oscillations within the interlocked feedback model of Drosophila circadian rhythm. J Theor Biol 210:401-406, 2001
    • (2001) J Theor Biol , vol.210 , pp. 401-406
    • Ueda, H.R.1    Hagiwara, M.2    Kitano, H.3
  • 11
    • 0034644270 scopus 로고    scopus 로고
    • The segment polarity network is a robust developmental module
    • von Dassow G, Meir E, Munro EM, Odell GM: The segment polarity network is a robust developmental module. Nature 406:188-192, 2000
    • (2000) Nature , vol.406 , pp. 188-192
    • Dassow, G.1    Meir, E.2    Munro, E.M.3    Odell, G.M.4
  • 12
    • 0034712843 scopus 로고    scopus 로고
    • Robust perfect adaptation in bacterial chemotaxis through integral feedback control
    • Yi TM, Huang Y, Simon MI, Doyle J: Robust perfect adaptation in bacterial chemotaxis through integral feedback control. Proc Natl Acad Sci USA 97:4649-4653, 2000
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4649-4653
    • Yi, T.M.1    Huang, Y.2    Simon, M.I.3    Doyle, J.4
  • 14
    • 0037133146 scopus 로고    scopus 로고
    • Complexity and robustness
    • Carlson JM, Doyle J: Complexity and robustness. Proc Natl Acad Sci USA 99 (Suppl. 1):2538-2545, 2002
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.SUPPL. 1 , pp. 2538-2545
    • Carlson, J.M.1    Doyle, J.2
  • 15
    • 0036500834 scopus 로고    scopus 로고
    • Reverse engineering of biological complexity
    • Csete ME, Doyle JC: Reverse engineering of biological complexity. Science 295:1664-1669, 2002
    • (2002) Science , vol.295 , pp. 1664-1669
    • Csete, M.E.1    Doyle, J.C.2
  • 16
    • 0344010691 scopus 로고    scopus 로고
    • Cancer robustness: Tumour tactics
    • Kitano H: Cancer robustness: tumour tactics. Nature 426:125, 2003
    • (2003) Nature , vol.426 , pp. 125
    • Kitano, H.1
  • 17
    • 1542619848 scopus 로고    scopus 로고
    • Cancer as a robust system: Implications for anticancer therapy
    • Kitano H: Cancer as a robust system: implications for anticancer therapy. Nat Rev Cancer 4:227-235, 2004
    • (2004) Nat Rev Cancer , vol.4 , pp. 227-235
    • Kitano, H.1
  • 18
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539-553, 1998
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 20
    • 0030795740 scopus 로고    scopus 로고
    • The changing face of macrovascular disease in non-insulin-dependent diabetes mellitus: An epidemic in progress
    • Zimmet PZ, Alberti KG: The changing face of macrovascular disease in non-insulin-dependent diabetes mellitus: an epidemic in progress. Lancet 350 (Suppl. 1):S1-S4, 1997
    • (1997) Lancet , vol.350 , Issue.SUPPL. 1
    • Zimmet, P.Z.1    Alberti, K.G.2
  • 21
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P, Alberti KG, Shaw J: Global and societal implications of the diabetes epidemic. Nature 414:782-787, 2001
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3
  • 22
    • 0023029455 scopus 로고
    • Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages
    • Newsholme P, Curi R, Gordon S, Newsholme EA: Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. Biochem J 239:121-125, 1986
    • (1986) Biochem J , vol.239 , pp. 121-125
    • Newsholme, P.1    Curi, R.2    Gordon, S.3    Newsholme, E.A.4
  • 23
    • 0028864403 scopus 로고
    • Modulation of macrophage proliferation by hyperglycemia
    • Liu YJ, Saini A, Cohen DJ, Ooi BS: Modulation of macrophage proliferation by hyperglycemia. Mol Cell Endocrinol 114:187-192, 1995
    • (1995) Mol Cell Endocrinol , vol.114 , pp. 187-192
    • Liu, Y.J.1    Saini, A.2    Cohen, D.J.3    Ooi, B.S.4
  • 24
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JM, Halaas JL: Leptin and the regulation of body weight in mammals. Nature 395:763-770, 1998
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 26
    • 0035430665 scopus 로고    scopus 로고
    • Ghrelin: An orexigenic and somatotrophic signal from the stomach
    • Inui A: Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat Rev Neurosci 2:551-560, 2001
    • (2001) Nat Rev Neurosci , vol.2 , pp. 551-560
    • Inui, A.1
  • 27
    • 0035856949 scopus 로고    scopus 로고
    • Insulin signalling and the regulation of glucose and lipid metabolism
    • Saltiel AR, Kahn CR: Insulin signalling and the regulation of glucose and lipid metabolism. Nature 414:799-806, 2001
    • (2001) Nature , vol.414 , pp. 799-806
    • Saltiel, A.R.1    Kahn, C.R.2
  • 28
    • 0036830636 scopus 로고    scopus 로고
    • SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
    • Rui L, Yuan M, Frantz D, Shoelson S, White MF: SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2. J Biol Chem 277:42394-42398, 2002
    • (2002) J Biol Chem , vol.277 , pp. 42394-42398
    • Rui, L.1    Yuan, M.2    Frantz, D.3    Shoelson, S.4    White, M.F.5
  • 31
    • 0038039463 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha: A key regulator of adipose tissue mass
    • Warne JP: Tumour necrosis factor alpha: a key regulator of adipose tissue mass. J Endocrinol 177:351-355, 2003
    • (2003) J Endocrinol , vol.177 , pp. 351-355
    • Warne, J.P.1
  • 34
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM: Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87-91, 1993
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 35
    • 0028587742 scopus 로고
    • Tumor necrosis factor alpha: A key component of the obesity-diabetes link
    • Hotamisligil GS, Spiegelman BM: Tumor necrosis factor alpha: a key component of the obesity-diabetes link. Diabetes 43:1271-1278, 1994
    • (1994) Diabetes , vol.43 , pp. 1271-1278
    • Hotamisligil, G.S.1    Spiegelman, B.M.2
  • 37
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS: Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389:610-614, 1997
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 40
    • 0032735973 scopus 로고    scopus 로고
    • Insulin resistance and inflammation in an evolutionary perspective: The contribution of cytokine genotype/phenotype to thriftiness
    • Fernandez-Real JM, Ricart W: Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftiness. Diabetologia 42:1367-1374, 1999
    • (1999) Diabetologia , vol.42 , pp. 1367-1374
    • Fernandez-Real, J.M.1    Ricart, W.2
  • 42
    • 0036346172 scopus 로고    scopus 로고
    • Glucose, but not glutamine, protects against spontaneous and anti-Fas antibody-induced apoptosis in human neutrophils
    • Healy DA, Watson RW, Newsholme P: Glucose, but not glutamine, protects against spontaneous and anti-Fas antibody-induced apoptosis in human neutrophils. Clin Sci (Lond) 103:179-189, 2002
    • (2002) Clin Sci (Lond) , vol.103 , pp. 179-189
    • Healy, D.A.1    Watson, R.W.2    Newsholme, P.3
  • 45
    • 0347985272 scopus 로고    scopus 로고
    • Obesity-induced inflammatory changes in adipose tissue
    • Wellen KE, Hotamisligil GS: Obesity-induced inflammatory changes in adipose tissue. J Clin Invest 112:1785-1788, 2003
    • (2003) J Clin Invest , vol.112 , pp. 1785-1788
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 46
    • 0037468396 scopus 로고    scopus 로고
    • CD36-mediated endocytic uptake of advanced glycation end products (AGE) in mouse 3T3-L1 and human subcutaneous adipocytes
    • Kuniyasu A, Ohgami N, Hayashi S, Miyazaki A, Horiuchi S, Nakayama H: CD36-mediated endocytic uptake of advanced glycation end products (AGE) In mouse 3T3-L1 and human subcutaneous adipocytes. FEBS Lett 537:85-90, 2003
    • (2003) FEBS Lett , vol.537 , pp. 85-90
    • Kuniyasu, A.1    Ohgami, N.2    Hayashi, S.3    Miyazaki, A.4    Horiuchi, S.5    Nakayama, H.6
  • 47
    • 0033694663 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance and the role of the adipocyte
    • Hotamisligil GS: Molecular mechanisms of insulin resistance and the role of the adipocyte. Int J Obes Relat Metab Disord 24 (Suppl. 4):S23-S27, 2000
    • (2000) Int J Obes Relat Metab Disord , vol.24 , Issue.SUPPL. 4
    • Hotamisligil, G.S.1
  • 48
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM: IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271:665-668, 1996
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 49
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee M: Biochemistry and molecular cell biology of diabetic complications. Nature 414:813-820, 2001
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 50
    • 0036313033 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha suppresses adipocyte-spedfic genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: Nuclear factor-kappaB activation by TNF-alpha is obligatory
    • Ruan H, Hacohen N, Golub TR, Van Parijs L, Lodish HF: Tumor necrosis factor-alpha suppresses adipocyte-spedfic genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory. Diabetes 51:1319-1336, 2002
    • (2002) Diabetes , vol.51 , pp. 1319-1336
    • Ruan, H.1    Hacohen, N.2    Golub, T.R.3    Van Parijs, L.4    Lodish, H.F.5
  • 54
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P: Inflammation in atherosclerosis. Nature 420:868-874, 2002
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 55
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys
    • Hotta K, Funahashi T, Bodkin NL, Ortmeyer HK, Arita Y, Hansen BC, Matsuzawa Y: Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes 50:1126-1133, 2001
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.L.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6    Matsuzawa, Y.7
  • 56
    • 0035857020 scopus 로고    scopus 로고
    • New drug targets for type 2 diabetes and the metabolic syndrome
    • Moller DE: New drug targets for type 2 diabetes and the metabolic syndrome. Nature 414:821-827, 2001
    • (2001) Nature , vol.414 , pp. 821-827
    • Moller, D.E.1
  • 57
    • 0035056155 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor (PPAR) gamma agonists for diabetes
    • Moller DE, Greene DA: Peroxisome proliferator-activated receptor (PPAR) gamma agonists for diabetes. Adv Protein Chem 56:181-212, 2001
    • (2001) Adv Protein Chem , vol.56 , pp. 181-212
    • Moller, D.E.1    Greene, D.A.2
  • 60
    • 0346219295 scopus 로고    scopus 로고
    • Effect of thiazolidinediones on body weight in patients with diabetes mellitus
    • Fonseca V: Effect of thiazolidinediones on body weight in patients with diabetes mellitus. Am J Med 115 (Suppl. 8A):42S-48S, 2003
    • (2003) Am J Med , vol.115 , Issue.SUPPL. 8A
    • Fonseca, V.1
  • 61
    • 0347480396 scopus 로고    scopus 로고
    • Clinical use of thiazolidinediones: Recommendations
    • Abrahamson MJ: Clinical use of thiazolidinediones: recommendations. Am J Med 115 (Suppl. 8A):116S-120S, 2003
    • (2003) Am J Med , vol.115 , Issue.SUPPL. 8A
    • Abrahamson, M.J.1
  • 62
    • 0035037583 scopus 로고    scopus 로고
    • Tumour necrosis factor as a therapeutic target in rheumatoid arthritis and other chronic inflammatory diseases: The clinical experience with infliximab (REMICADE)
    • Bondeson J, Maini RN: Tumour necrosis factor as a therapeutic target in rheumatoid arthritis and other chronic inflammatory diseases: the clinical experience with infliximab (REMICADE). Int J Clin Pract 55:211-216, 2001
    • (2001) Int J Clin Pract , vol.55 , pp. 211-216
    • Bondeson, J.1    Maini, R.N.2
  • 63
    • 0029906375 scopus 로고    scopus 로고
    • Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
    • Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R: Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 45:881-885, 1996
    • (1996) Diabetes , vol.45 , pp. 881-885
    • Ofei, F.1    Hurel, S.2    Newkirk, J.3    Sopwith, M.4    Taylor, R.5
  • 65
    • 4544371460 scopus 로고    scopus 로고
    • A graphical notation for biochemical networks
    • Kitano H: A graphical notation for biochemical networks. Biosilico 1:169-176, 2003
    • (2003) Biosilico , vol.1 , pp. 169-176
    • Kitano, H.1
  • 66
    • 9444266171 scopus 로고    scopus 로고
    • CellDesigner: A process diagram editor for gene-regulatory and biochemical networks
    • Funahashi A, Kitano H: CellDesigner: a process diagram editor for gene-regulatory and biochemical networks. Biosilico 1:159-162, 2003
    • (2003) Biosilico , vol.1 , pp. 159-162
    • Funahashi, A.1    Kitano, H.2
  • 67
    • 0036372791 scopus 로고    scopus 로고
    • The ERATO Systems Biology Workbench: Enabling interaction and exchange between software tools for computational biology
    • Hucka M, Finney A, Sauro HM, Bolouri H, Doyle J, Kitano H: The ERATO Systems Biology Workbench: enabling interaction and exchange between software tools for computational biology. Pac Symp Biocomput 450-461, 2002
    • (2002) Pac Symp Biocomput , pp. 450-461
    • Hucka, M.1    Finney, A.2    Sauro, H.M.3    Bolouri, H.4    Doyle, J.5    Kitano, H.6
  • 68
    • 0347511691 scopus 로고    scopus 로고
    • Next generation simulation tools: The Systems Biology Workbench and BioSPICE integration
    • Sauro HM, Hucka M, Finney A, Wellock C, Bolouri H, Doyle J, Kitano H: Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration. Omics 7:355-372, 2003
    • (2003) Omics , vol.7 , pp. 355-372
    • Sauro, H.M.1    Hucka, M.2    Finney, A.3    Wellock, C.4    Bolouri, H.5    Doyle, J.6    Kitano, H.7
  • 69
    • 0142215247 scopus 로고    scopus 로고
    • Analysis of switched and hybrid systems: Beyond piecewise quadratic methods
    • New York, IEEE
    • Prajna S, Papachristodoulou A. Analysis of switched and hybrid systems: beyond piecewise quadratic methods. In Proceedings of American Control Conference. New York, IEEE, 2003, p. 2779-2784
    • (2003) Proceedings of American Control Conference , pp. 2779-2784
    • Prajna, S.1    Papachristodoulou, A.2


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