Contribution of microglia/macrophages to expansion of infarction and response of oligodendrocytes after focal cerebral ischemia in rats

Stroke

Volumn 31, Issue 7, 2000, Pages 1735-1743

  Mabuchi, Takuma ^a   Kitagawa, Kazuo ^b   Ohtsuki, Toshiho ^b   Kuwabara, Keisuke ^b   Yagita, Yoshiki ^b   Yanagihara, Takehiko ^b   Hori, Masatsugu ^b   Matsumoto, Masayasu ^b  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

Apoptosis; Cerebral infarction; Interleukins; Macrophages; Microglia; Oligodendrocytes; Rats

Indexed keywords

DNA FRAGMENT; INTERLEUKIN 1BETA; PROTEIN BAX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFARCTION; BRAIN ISCHEMIA; CYTOKINE PRODUCTION; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

EID: 0033933546     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.31.7.1735     Document Type: Article

References (42)

1. Garcia JH, Yoshida Y, Chen H, Li Y, Zhang ZG, Lian J, Chen S, Chopp M. Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat. Am J Pathol. 1993;1993:142:623-635.
2. Ginsberg MD, Pulsinelli WA. The ischemic penumbra, injury thresholds, and the therapeutic window for acute stroke. Ann Neurol. 1994;36: 553-554.
3. Hossmann KA. Viability thresholds and the penumbra of focal ischemia. Ann Neurol. 1994;36:557-565.
4. Del Zoppo GJ, Schmid Schonbein GW, Mrin E, Copeland BR, Chang CM. Polymorphonuclear leukocytes occlude capillaries following middle cerebral artery occlusion and reperfusion in baboons. Stroke. 1991;22: 1276-1283.
5. Kochanek PM, Hallenbeck JM. Polymorphonuclear leukocytes and monocytes/macrophages in the pathogenesis of cerebral ischemia and stroke. Stroke. 1992;23:1367-1379.
6. Morioka T, Kalehua AN, Streit WJ. Characterization of microglial reaction after middle cerebral artery occlusion in rat brain. J Comp Neurol. 1993;327:123-132.
7. Mandai K, Matsumoto M, Kitagawa K, Matsushita K, Ohtsuki T, Mabuchi T, Colman DR, Kamada T, Yanagihara T. Ischemic damage and subsequent proliferation of oligodendrocytes in focal cerebral ischemia. Neuroscience. 1997;77:849-861.
8. Volpe JJ. Brain injury in the premature infant: current concepts. Prev Med. 1994;23:638-645.
9. Pantoni L, Garcia JH, Gutierrez JA. Cerebral white matter is highly vulnerable to ischemia. Stroke. 1996;27:1641-1647.
10. Ellison JA, Velier JJ, Spera P, Jonak ZL, Wang X, Barone FC, Feuerstein GZ. Osteopontin and its integrin receptor αvβ3 are upregulated during formation of the glial scar after focal ischemia. Stroke. 1998;29: 1698-1707.
11. Koizumi J, Yoshida Y, Nakazawa T, Ooneda G. Experimental studies of ischemic brain edema, I: a new experimental model of cerebral embolism in rats in which recirculation can be introduced in the ischemic area. Jpn J Stroke. 1986;8:1-8.
12. Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke. 1989;20: 84-91.
13. Kitagawa K, Matsumoto M, Niinobe M, Mikoshiba K, Hata R, Ueda H, Handa N, Fukunaga R, Isaka Y, Kimura K, Kamada T. Microtubule-associated protein 2 as a sensitive marker for cerebral ischemic damage: immunohistochemical investigation of dendritic damage. Neuroscience. 1989;31:401-411.
14. Davies CA, Loddick SA, Tourlmond S, Stroemer RP, Hunt J, Rothwell NJ. The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab. 1999;19:87-98.
15. Streit WJ, Kreutzberg GW. Lectin binding by resting and reactive microglia. J Neurocytol. 1987;16:249-260.
16. Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol. 1992;119:493-501.
17. 3 during focal cerebral ischemia. J Cereb Blood Flow Metab. 1999;19:1038-1050.
18. Astrup J, Symon L, Siesjo BK. Thresholds in cerebral ischemia: the ischemic penumbra. Stroke. 1981;12:723-725.
19. Garcia JH, Liu KF, Yoshida Y, Chen S, Lian J. Brain microvessels: factors altering their patency after the occlusion of a middle cerebral artery (Wistar rats). Am J Pathol. 1994;145:728-740.
20. Vogel J, Hermes A, Kuschinsky W. Evolution of microcirculatory disturbances after permanent middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab. 1999;19:1322-1328.
21. Yanagihara T, Yoshimine T, Morimoto K, Yamamoto K, Homburger HA. Immunohistochemical investigation of cerebral ischemia in gerbils. J Neuropathol Exp Neurol. 1985;44:204-215.
22. Hossmann KA. Glutamate-mediated injury in focal cerebral ischemia: the excitotoxin hypothesis revised. Brain Pathol. 1994;4:23-36.
23. Back T, Ginsberg MD, Dietrich WD, Watson BD. Induction of spreading depression in the ischemic hemisphere following experimental middle cerebral artery occlusion: effect on infarct morphology. J Cereb Blood Flow Metab. 1996;16:202-213.
24. Yamasaki Y, Susuki T, Yamaya H, Matsuura N, Onodera H, Kogure K. Possible involvement of interleukin-1 in ischemic brain edema formation. Neurosci Lett. 1992;142:45-47.
25. Loddick SA, Rothwell NJ. Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischemia in the rat. J Cereb Blood Flow Metab. 1996;16:932-940.
26. Gregersen R, Lambertsen K, Finsen B. Microglia and macrophages are the major source of tumor necrosis factor in permanent middle cerebral artery occlusion in mice. J Cereb Blood Flow Metab. 2000:20:53-65.
27. Wang X, Yue TL, White RF, Gagnon RC, Feuerstein GZ. Concomitant cortical expression of TNF-alpha and IL-1 beta mRNAs following early response gene expression in transient focal ischemia. Mol Chem Neuropathol. 1994;23:103-114.
28. Iadecola C, Zhang F, Xu X. Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am J Physiol. 1995;268: R286-R292.
29. Tagaya M, Liu KF, Copeland B, Seiffert D, Engler R, Garcia JH, del Zoppo GL. DNA scission after focal brain ischemia: temporal differences in two species. Stroke. 1997;28:1245-1254.
30. Matsuo Y, Onodera H, Shiga Y, Nakamura M, Ninomiya M, Kihara T, Kogure K. Correlation between myeloperoxidase-quantified neutrophil accumulation and ischemic brain injury in the rat: effects of neutrophil depletion. Stroke. 1994;25:1469-1475.
31. Brophy PJ, Boccaccio GL, Colman DR. The distribution of myelin basic protein mRNAs within myelinating oligodendrocytes. Trends Neurosci. 1993;16:515-521.
32. Brack W, Schmied M, Suchanek G, Bruck Y, Breitshopf H, Poser S, Piddlesden S, Lassmann H. Oligodendrocytes in the early course of multiple sclerosis. Ann Neurol. 1994;36:65-73.
33. Rodriguez M, Prayoonwiwat N, Howe C, Sanbork K. Proteolipid protein gene expression in demyelination and remyelination of the central nervous system: a model for multiple sclerosis. J Neuropathol Exp Neurol. 1994;53:136-143.
34. Merrill JE, Ignarro LJ, Sherman MP, Melinek J, Lane TE. Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J Immunol. 1993;151:2132-2141.
35. Mitrovic B, Martin FC, Charled AC, Ignarro LJ, Anton PA, Shanahan F, Merrill JE. Neurotransmitters and cytokines in CNS pathology. Prog Brain Res. 1994;103:319-330.
36. Crowe MJ, Bresnahan JC, Shuman SL, Masters JN, Beattie MS. Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys. Nat Med. 1997;3:73-76.
37. Gehrmann J, Banati RB. Microglial turnover in the injured CNS: activated microglia undergo delayed DNA fragmentation following peripheral nerve injury. J Neuropathol Exp Neurol. 1995;54:680-688.
38. Udo K, Reed JC, Brune B. Bcl-2 protects macrophages from nitric oxide-induced apoptosis. J Biol Chem. 1996;271:20192-20197.
39. Singhal PC, Sharma P, Kapasi AA, Reddy K, Franki N, Gibbons N. Morphine enhances macrophage apoptosis. J Immunol. 1998;160: 1886-1893.
40. Brierley JB, Graham DI. Hypoxia and vascular disorders of the central nervous system. In: Adams JH, Corsellis JAN, Duchen LW, eds. Greenfield's Neuropathology. 4th ed. London, England: Edward Arnold; 1984: 125-207.
41. Lehrmann E, Christensen T, Zimmer J, Diemer NH, Finsen B. Microglial and macrophage reactions mark progressive changes and define the penumbra in the rat neocortex and striatum after transient middle cerebral artery occlusion. J Comp Neurol. 1997;386:461-476.
42. Norenberg MD. Astrocyte responses to CNS injury. J Neuropathol Exp Neurol. 1994;53:213-220.