Pten (phosphatase and tensin homologue gene) haploinsufficiency promotes insulin hypersensitivity

Diabetologia

Volumn 50, Issue 2, 2007, Pages 395-403

  Wong, J T ^a,b   Kim, P T W ^b   Peacock, J W ^a,b   Yau, T Y ^a,b   Mui, A L F ^b   Chung, S W ^b   Sossi, V ^b   Doudet, D ^c   Green, D ^d   Ruth, T J ^c   Parsons, R ^e   Verchere, C B ^b   Ong, C J ^a,b  

^a VANCOUVER GENERAL HOSPITAL   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c TRIUMF   (Canada)

^d Canadian Centre for Applied Research in Cancer Control   (Canada)

^e Columbia University ^*  (United States)

Author keywords

Glucose uptake; Insulin hypersensitivity; Insulin sensitivity; Pten haploinsufficiency

Indexed keywords

GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; IN VITRO STUDY; IN VIVO STUDY; INSULIN SENSITIVITY; MOUSE; MUSCLE FIBER CULTURE; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; WESTERN BLOTTING; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; BLOOD GLUCOSE; CROSSES, GENETIC; DEOXYGLUCOSE; DIABETES MELLITUS, TYPE 2; FLUORODEOXYGLUCOSE F18; GLUCOSE; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORTER TYPE 1; GLUCOSE TRANSPORTER TYPE 4; HETEROZYGOTE DETECTION; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; POSITRON-EMISSION TOMOGRAPHY; PTEN PHOSPHOHYDROLASE;

EID: 33846493564     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-006-0531-x     Document Type: Article

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