PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/AKT pathway in 3T3-L1 adipocytes

Journal of Biological Chemistry

Volumn 280, Issue 23, 2005, Pages 22523-22529

  Tang, Xiaoqing ^a   Powelka, Aimee M ^a   Soriano, Neil A ^a   Czech, Michael P ^a   Guilherme, Adilson ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELLS; CHROMOSOMES; ENZYMES; GLUCOSE; METABOLISM;

GLUCOSE HEMOSTASIS; GLUCOSE TRANSPORT; INSULIN SIGNALING; KINASE;

INSULIN;

GLYCOGEN SYNTHASE KINASE 3ALPHA; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN SH2; PROTEIN SHIP2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE SILENCING; GLUCOSE TRANSPORT; HEXOSE TRANSPORT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 3T3-L1 CELLS; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE DELETION; GENE SILENCING; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INSULIN; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 20444487358     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M501949200     Document Type: Article

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