Use of RNA interference-mediated gene silencing and adenoviral overexpression to elucidate the roles of AKT/protein kinase B isoforms in insulin actions

Journal of Biological Chemistry

Volumn 278, Issue 30, 2003, Pages 28312-28323

  Katome, Takashi ^a,b   Obata, Toshiyuki ^a,d   Matsushima, Rie ^a   Masuyama, Norihisa ^c   Cantley, Lewis C ^d   Gotoh, Yukiko ^c   Kishi, Kazuhiro ^a   Shiota, Hiroshi ^b   Ebina, Yousuke ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; ENZYMES; GENES; GLUCOSE; INSULIN; RNA;

HOMEOSTASIS;

BIOCHEMISTRY;

ADENOVIRUS VECTOR; DEOXYGLUCOSE; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; PROTEIN KINASE B; RNA; SERINE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CHO CELL; CONTROLLED STUDY; GENE SILENCING; GLUCOSE HOMEOSTASIS; GLUCOSE TRANSPORT; GLYCOGEN SYNTHESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

3T3 CELLS; ADENOVIRIDAE; ANIMALS; BASE SEQUENCE; BRAIN; CHO CELLS; COS CELLS; CRICETINAE; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE LIBRARY; GENE SILENCING; GENETIC TECHNIQUES; GLUCOSE TRANSPORTER TYPE 4; GLYCOGEN; IMMUNOBLOTTING; INSULIN; LUCIFERASES; MICE; MOLECULAR SEQUENCE DATA; MONOSACCHARIDE TRANSPORT PROTEINS; MUSCLE PROTEINS; PLASMIDS; PRECIPITIN TESTS; PROTEIN ISOFORMS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA INTERFERENCE; TIME FACTORS;

ADENOVIRIDAE; ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; VECTORS;

EID: 0041845231     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302094200     Document Type: Article

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