Diverse and potent chemokine production by lung CD11bhigh dendritic cells in homeostasis and in allergic lung inflammation

Journal of Immunology

Volumn 178, Issue 3, 2007, Pages 1882-1895

  Beaty, Steven R ^a   Rose Jr , C Edward ^a   Sung, Sun Sang J ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHAEBETA7 INTEGRIN; CD103 ANTIGEN; CD11B ANTIGEN; CHEMOKINE; GLYCOPROTEIN P 15095; INTEGRIN; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRONCHUS HYPERREACTIVITY; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HELPER CELL; HOMEOSTASIS; LUNG ALVEOLUS MACROPHAGE; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SUPERNATANT; TH2 CELL;

EID: 33846490362     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.3.1882     Document Type: Article

References (70)

1. Busse, W. W., and R. F. Lemanske, Jr. 2001. Asthma. N. Engl. J. Med. 344: 350-362.
2. Kay, A. B. 2001. Allergy and allergic diseases: first of two parts. N. Engl. J. Med. 344: 30-37.
3. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252.
4. Steinman, R. M. 2003. Some interfaces of dendritic cell biology. APMIS 111: 675-697.
5. Holt, P. G., and J. W. Upham. 2004. The role of dendritic cells in asthma. Curr. Opin. Allergy Clin. Immunol. 4: 39-44.
6. Havenith, C. E., P. P. van Miert, A. J. Breedijk, R. H. Beelen, and E. C. Hoefsmit. 1993. Migration of dendritic cells into the draining lymph nodes of the lung after intratracheal instillation. Am. J. Respir. Cell Mol. Biol. 9: 484-488.
7. + dendritic cells shift dynamically from lung to lymph node after an airway challenge with soluble antigen. J. Exp. Med. 181: 1275-1283.
8. Lambrecht, B. N., B. Salomon, D. Klatzmann, and R. A. Pauwels. 1998. Dendritic cells are required for the development of chronic eosinophilic airway inflammation in response to inhaled antigen in sensitized mice. J. Immunol. 160: 4090-4097.
9. + dendritic cells during allergen challenge abrogates the characteristic features of asthma. J. Exp. Med. 201: 981-991.
10. Sertl, K., T. Takemura, E. Tschachler, V. J. Ferrans, M. A. Kaliner, and E. M. Shevach. 1986. Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J. Exp. Med. 163: 436-451.
11. Holt, P. G., S. Haining, D. J. Nelson, and J. D. Sedgwick. 1994. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J. Immunol. 153: 256-261.
12. Gong, J., K. McCarthy, J. Telford, T. Tamatani, M. Miyasaka, and E. Schneeberger. 1992. Intraepithelial airway dendritic cells: a distinct subset of pulmonary dendritic cells obtained by microdissection. J. Exp. Med. 175: 797-807.
13. Masten, B. J., G. K. Olson, D. F. Kusewitt, and M. F. Lipscomb. 2004. Flt3 ligand preferentially increases the number of functionally active myeloid dendritic cells in the lungs of mice. J. Immunol. 172: 4077-4083.
14. 7 integrin-positive epithelial dendritic cell population expressing Langerin and tight junction proteins. J. Immunol. 176: 2161-2172.
15. 7 by a major subpopulation of dendritic cells in mice. Eur. J. Immunol. 23: 3365-3368.
16. 7 integrins define a subset of dendritic cells in peripheral lymph nodes with unique adhesive and antigen uptake properties. J. Immunol. 172: 282-291.
17. Annacker, O., J. L. Coombes, V. Malmstrom, H. H. Uhlig, T. Bourne, B. Johansson-Lindbom, W. W. Agace, C. M. Parker, and F. Powrie. 2005. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J. Exp. Med. 202: 1051-1061.
18. + dendritic cells in the regulation of tissue-selective T cell homing. J. Exp. Med. 202: 1063-1073.
19. Nelson, D. J., C. McMenamin, A. S. McWilliam, M. Brenan, and P. G. Holt. 1994. Development of the airway intraepithelial dendritic cell network in the rat from class II major histocompatibility (Ia)-negative precursors: differential regulation of Ia expression at different levels of the respiratory tract. J. Exp. Med. 179: 203-212.
20. von Garnier, C., L. Filgueira, M. Wikstrom, M. Smith, J. A. Thomas, D. H. Strickland, P. G. Holt, and P. A. Stumbles. 2005. Anatomical location determines the distribution and function of dendritic cells and other APCs in the respiratory tract. J. Immunol. 175: 1609-1618.
21. Lukacs, N. W. 2001. Role of chemokines in the pathogenesis of asthma. Nat. Rev. Immunol. 1: 108-116.
22. Gutierrez-Ramos. 2000. Non-redundant functional groups of chemokines operate in a coordinate manner during the inflammatory response in the lung. Immunol. Rev. 177: 31-42.
23. Moser, B., M. Wolf, A. Walz, and P. Loetscher. 2004. Chemokines: multiple levels of leukocyte migration control. Trends Immunol. 25: 75-84.
24. Stumbles, P. A., J. A. Thomas, C. L. Pimm, P. T. Lee, T. J. Venaille, S. Proksch, and P. G. Holt. 1998. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and require obligatory cytokine signals for induction of Th1 immunity. J. Exp. Med. 188: 2019-2031.
25. Constant, S. L., J. L. Brogdon, D. A. Piggott, C. A. Herrick, I. Visintin, N. H. Ruddle, and K. Bottomly. 2002. Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ. J. Clin. Invest. 110: 1441-1448.
26. - subclasses of dendritic cells direct the development of distinct T helper cells in vivo. J. Exp. Med 189: 587-592.
27. Rot, A., and U. H. von Andrian. 2004. Chemokines in innate and adaptive host defense: basic chemokinese grammar for immune cells. Annu. Rev. Immunol. 22: 891-928.
28. Barnes, P. J. 2004. Mediators of chronic obstructive pulmonary disease. Pharmacol. Rev. 56: 515-548.
29. Schuh, J. M., K. Blease, and C. M. Hogaboam. 2002. CXCR2 is necessary for the development and persistence of chronic fungal asthma in mice. J. Immunol. 168: 1447-1456.
30. -/- mice during chronic fungal allergic airway disease. J, Immunol. 165: 1564-1572.
31. Lukacs, N. W., D. M. Prosser, M. Wiekowski, S. A. Lira, and D. N. Cook. 2001. Requirement for the chemokine receptor CCR6 in allergic pulmonary inflammation. J. Exp. Med. 194: 551-555.
32. Kawasaki, S., H. Takizawa, H. Yoneyama, T. Nakayama, R. Fujisawa, M. Izumizaki, T. Imai, O. Yoshie, I. Homma, K. Yamamoto, and K. Matsushima. 2001. Intervention of thymus and activation-regulated chemokine attenuates the development of allergic airway inflammation and hyperresponsiveness in mice. J. Immunol. 166: 2055-2062.
33. Gonzalo, J. A., Y. Pan, C. M. Lloyd, G. Q. Jia, G. Yu, B. Dussault, C. A. Powers, A. E. Proudfoot, A. J. Coyle, D. Gearing, and J. C. Gutierrez-Ramos. 1999. Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation. J. Immunol. 163: 403-411.
34. Kim, Y., S.-s. J. Sung, W. A. Kuziel, S. Feldman, S. M. Fu, and C. E. Rose, Jr. 2001. Enhanced airway Th2 response after allergen challenge in mice deficient in CC chemokine receptor-2 (CCR2). J. Immunol. 166: 5183-5192.
35. Yamashita, N., H. Tashimo, Y. Matsuo, H. Ishida, K. Yoshiura, K. Sato, N. Yamashita, T. Kakiuchi, and K. Ohta. 2006. Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model. J. Allergy Clin. Immunol. 117: 1040-1046.
36. Grinnan, D., S.-S. Sung, J. A. Dougherty, A. R. Knowles, M. B. Allen, C. E. Rose III, H. Nakano, M. D. Gunn, S. M. Fu, C. Edward, and C. E. Rose, Jr. 2006. Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. J. Allergy Clin. Immunol. 118: 1234-1241.
37. Penna, G., M. Vulcano, A. Roncari, F. Facchetti, S. Sozzani, and L. Adorini. 2002. Cutting edge: differential chemokine production by myeloid and plasma-cytoid dendritic cells. J. Immunol. 169: 6673-6676.
38. Proietto, A. I., M. O'Keeffe, K. Gartlan, M. D. Wright, K. Shortman, L. Wu, and M. H. Lahoud. 2004. Differential production of inflammatory chemokines by murine dendritic cell subsets. Immunobiology 209: 163-172.
39. Megjugorac, N. J., H. A. Young, S. B. Amrute, S. L. Olshalsky, and P. Fitzgerald-Bocarsly. 2004. Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells. J. Leukocyte Biol. 75: 504-514.
40. + T cells. Eur. J. Immunol. 29: 2684-2694.
41. Li, C., and W. H. Wong. 2003. DNA-chip analyzer (dChip). In The Analysis of Gene Expression Data: Methods and Software. G. Parmigiani, E. S. Garrett, R. Irizarry, and S. L. Zeger, eds. Springer, New York, pp. 5.1-5.21.
42. Sung, S., C. E. Rose, and S. M. Fu. 2001. Intratracheal priming with ovalbumin-and ovalbumin 323-339 peptide-pulsed dendritic cells induces airway hyperresponsiveness, lung eosinophilia, goblet cell hyperplasia, and inflammation. J. Immunol. 166: 1261-1271.
43. Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176: 1693-1702.
44. Nishikomori, R., R. O. Ehrhardt, and W. Strober. 2000. T helper type 2 cell differentiation occurs in the presence of interleukin 12 receptor β2 chain expression and signaling. J. Exp. Med. 191: 847-858.
45. Lore, K., A. Sonnerborg, A.-L. Spetz, U. Andersson, and J. Andersson. 1998. Immunocytochemical detection of cytokines and chemokines in Langerhans cells and in vitro derived dendritic cells. J. Immunol. Methods. 214: 97-111.
46. Lyons, A. B., and C. R. Parish. 1994. Determination of lymphocyte division by flow cytometry. J. Immunol. Methods 171: 131-137.
47. + regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198: 235-247.
48. Curran-Everett, D. 2000. Multiple comparisons: philosophies and illustrations. Am. J. Physiol. 279: R1-R8.
49. Murphy, P. M., M. Baggiolini, I. F. Charo, C. A. Hebert, R. Horuk, K. Matsushima, L. H. Miller, J. J. Oppenheim, and C. A. Power. 2000. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52: 145-176.
50. Asselin-Paturel, C., A. Boonstra, M. Dalod, I. Durand, N. Yessaad, C. Dezutter-Dambuyant, A. Vicari, A. O'Garra, C. Biron, F. Briere, and G. Trinchieri. 2001. Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology. Nat. Immunol. 2: 1144-1150.
51. McWilliam, A. S., D. Nelson, J. A. Thomas, and P. G. Holt. 1994. Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces. J. Exp. Med. 179: 1331-1336.
52. Levitt, R., and S. Ewart. 1995. Genetic susceptibility to atracurium-induced bronchoconstriction. Am. J. Respir. Crit. Care Med. 151: 1537-1542.
53. Hochrein, H., K. Shortman, D. Vremec, B. Scott, P. Hertzog, and M. O'Keeffe. 2001. Differential production of IL-12, IFN-α, and IFN-γ by mouse dendritic cell subsets. J. Immunol. 166: 5448-5455.
54. Bisset, L. R., and P. Schmid-Grendelmeier. 2005. Chemokines and their receptors in the pathogenesis of allergic asthma: progress and perspective. Curr. Opin. Pulm. Med. 11: 35-42.
55. Gonzalo, J. A., C. M. Lloyd, D. Wen, J. P. Albar, T. N. Wells, A. Proudfoot, A. C. Martinez, M. Dorf, T. Bjerke, A. J. Coyle, and J. C. Gutierrez-Ramos. 1998. The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness. J. Exp. Med. 188: 157-167.
56. Lloyd, C. M., T. Delaney, T. Nguyen, J. Tian, A. C. Martinez, A. J. Coyle, and J. C. Gutierrez-Ramos. 2000. CC chemokine receptor (CCR)3/eotaxin is followed by CCR4/monocyte-derived chemokine in mediating pulmonary T helper lymphocyte type 2 recruitment after serial antigen challenge in vivo. J. Exp. Med. 191: 265-274.
57. Ma, B., Z. Zhu, R. J. Homer, C. Gerard, R. Stricter, and J. A. Elias. 2004. The C10/CCL6 chemokine and CCR1 play critical roles in the pathogenesis of IL-13-induced inflammation and remodeling. J. Immunol. 172: 1872-1881.
58. Hogaboam, C. M., C. S. Gallinat, D. D. Taub, R. M. Stricter, S. L. Kunkel, and N. W. Lukacs. 1999. Immunomodulatory role of C10 chemokine in a murine model of allergic bronchopulmonary aspergillosis. J. Immunol. 162: 6071-6079.
59. Sallusto, F., B. Palermo, D. Lenig, M. Miettinen, S. Matikainen, I. Julkunen, R. Forster, R. Burgstahler, M. Lipp, and A. Lanzavecchia. 1999. Distinct patterns and kinetics of chemokine production regulate dendritic cell function. Eur. J. Immunol. 29: 1617-1625.
60. Fischer, F. R., Y. Luo, M. Luo, L. Santambrogio, and M. E. Dorf. 2001. RANTES-induced chemokine cascade in dendritic cells. J. Immunol. 167: 1637-1643.
61. Fujita, H., A. Asahina, M. Sugaya, K. Nakamura, P. Gao, H. Fujiwara, and K. Tamaki. 2005. Differential production of Th1- and Th2-type chemokines by mouse Langerhans cells and splenic dendritic cells. J. Invest. Dermatol. 124: 343-350.
62. Penna, G., M. Vulcano, S. Sozzani, and L. Adorini. 2002. Differential migration behavior and chemokine production by myeloid and plasmacytoid dendritic cells. Hum. Immunol. 63: 1164-1171.
63. Li, L., Y. Xia, A. Nguyen, Y. H. Lai, L. Feng, T. R. Mosmann, and D. Lo. 1999. Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. J. Immunol. 162: 2477-2487.
64. Thorley, A. J., P. Goldstraw, A. Young, and T. D. Tetley. 2005. Primary human alveolar type II epithelial cell CCL20 (macrophage inflammatory protein-3α)-induced dendritic cell migration. Am. J. Respir. Cell Mol. Biol. 32: 262-267.
65. Kriehuber, E., S. Breiteneder-Geleff, M. Groeger, A. Soleiman, S. F. Schoppmann, G. Stingl, D. Kerjaschki, and D. Maurer. 2001. Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J. Exp. Med. 194: 797-808.
66. Iwasaki, A., and B. L. Kelsall. 2000. Localization of distinct Peyer's patch dendritic cell subsets and their recruitment by chemokines macrophage inflammatory protein (MIP)-3α, MIP-3β, and secondary lymphoid organ chemokine. J. Exp. Med. 191: 1381-1394.
67. Martin-Fontecha, A., S. Sebastiani, U. E. Hopken, M. Uguccioni, M. Lipp, A. Lanzavecchia, and F. Sallusto. 2003. Regulation of dendritic cell migration to the draining lymph node: impact on T lymphocyte traffic and priming. J. Exp. Med. 198: 615-621.
68. + T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor. J. Exp. Med. 201: 1037-1044.
69. Shieh, C.-C., B. K. Sadasivan, G. J. Russell, M. P. Schon, C. M. Parker, and M. B. Brenner. 1999. Lymphocyte adhesion to epithelia and endothelia mediated by the lymphocyte endothelial-epithelial cell adhesion molecule glycoprotein. J. Immunol. 163: 1592-1601.
70. Niess, J. H., S. Brand, X. Gu, L. Landsman, S. Jung, B. A. McCormick, J. M. Vyas, M. Boes, H. L. Ploegh, J. G. Fox, et al. 2005. CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance. Science 307: 254-258.