CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1

Science

Volumn 312, Issue 5771, 2006, Pages 269-272

  Ling, Jian Qun ^a   Li, Tao ^a   Hu, Ji Fan ^a   Vu, Thanh H ^a   Chen, Hui Ling ^a,b   Qiu, Xin Wen ^a,b   Cherry, Athena M ^c   Hoffman, Andrew R ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL MODIFICATION; CHROMOSOMES; CONFORMATIONS; DATA RECORDING; DNA; ELECTRIC INSULATORS; FLUORESCENCE; RNA;

CCCTC-BINDING FACTOR (CTCF); GENE TRANSCRIPTION; IN SITU HYBRIDIZATION; INSULIN-LIKE GROWTH FACTOR;

GENETIC ENGINEERING;

BINDING PROTEIN; DNA; PROTEIN CTCF; RNA; UNCLASSIFIED DRUG;

ALLELE; CHROMOSOME; DNA; FLUORESCENCE; GENE EXPRESSION; RNA;

ALLELE; ANIMAL CELL; ARTICLE; CHROMOSOME 11; CHROMOSOME 7; CHROMOSOME ANALYSIS; CHROMOSOME CONFORMATION CAPTURE; CHROMOSOME MAP; CONTROLLED STUDY; DNA RECOMBINATION; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENETIC TRANSCRIPTION; GENOME IMPRINTING; H19 GENE; IGF2 GENE; MOUSE; NF1 GENE; NONHUMAN; PRIORITY JOURNAL; TRANS SPLICING; WSB1 GENE;

ALLELES; ANIMALS; BINDING SITES; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOMES, MAMMALIAN; DNA-BINDING PROTEINS; EPISTASIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; GENOMIC IMPRINTING; IN SITU HYBRIDIZATION, FLUORESCENCE; INSULIN-LIKE GROWTH FACTOR II; MALE; MICE; NEUROFIBROMIN 1; REGULATORY ELEMENTS, TRANSCRIPTIONAL; REPRESSOR PROTEINS; RNA, UNTRANSLATED; TRANSCRIPTION, GENETIC; UBIQUITIN-PROTEIN LIGASES;

EID: 33645814398     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1123191     Document Type: Article

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30. This work was supported by NIH grants DK036054, DK065283, and HD047013; the March of Dimes; and the Research Service of the Department of Veterans Affairs. We thank J. E. Wrede for advice and assistance in performing the FISH analyses. We are indebted to M. Bartolomei, R. Feil, W. Reik, W. Dean, and A. Wagschal for providing us with cell lines, and to K. Pfeifer and U. Franke for BAC clones.