Transient homologous chromosome pairing marks the onset of X inactivation

Science

Volumn 311, Issue 5764, 2006, Pages 1149-1152

  Xu, Na ^a   Tsai, Chia Lun ^a   Lee, Jeannie T ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITION;

AUTOSOMAL INSERTION; MAMMALIAN X INACTIVATION; MUTUALLY EXCLUSIVE SILENCING;

CHROMOSOMES;

MEDICINE;

ALLELE; ARTICLE; AUTOSOME; CHROMOSOME PAIRING; GENE DOSAGE; HOMOLOGOUS RECOMBINATION; MAMMAL; MAMMALIAN GENETICS; NONHUMAN; PRIORITY JOURNAL; TSIX GENE; X CHROMOSOME; X CHROMOSOME INACTIVATION; XITE GENE; Y CHROMOSOME;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CHROMOSOME PAIRING; FEMALE; IN SITU HYBRIDIZATION, FLUORESCENCE; MALE; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MUTATION; REGULATORY ELEMENTS, TRANSCRIPTIONAL; RNA, UNTRANSLATED; STEM CELLS; TRANSGENES; X CHROMOSOME; X CHROMOSOME INACTIVATION;

MAMMALIA;

EID: 33644557773     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1122984     Document Type: Article

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22. We acknowledge B. Seed and R. Xavier for BAC-Abca2; B. K. Sun, K. D. Huynh, L. F. Zhang, Y. Ogawa, and M. E. Donohoe for critical reading of the manuscript; and all lab members for ongoing discussion. This work was supported by the National Institutes of Health and the Howard Hughes Medical Institute.