G protein-coupled receptors control vascular smooth muscle cell proliferation via pp60(c-src) and p21(ras)

American Journal of Physiology - Cell Physiology

Volumn 272, Issue 6 41-6, 1997, Pages

  Schieffer, Bernhard ^a   Drexler, Helmut ^a   Ling, Brian N ^b,c,d   Marrero, Mario B ^c  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b Renal Division   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Angiotensin II; Endothelin 1; Platelet derived growth factor; Thrombin; Tyrosine kinase

Indexed keywords

ANGIOTENSIN; ENDOTHELIN 1; GUANINE NUCLEOTIDE BINDING PROTEIN; PLATELET DERIVED GROWTH FACTOR; PROTEIN P21; PROTEIN TYROSINE KINASE; RAS PROTEIN; THROMBIN;

ANIMAL CELL; AORTA; ARTERIOSCLEROSIS; ARTICLE; BLOOD VESSEL INJURY; CELL PROLIFERATION; DNA SYNTHESIS; ELECTROPORATION; HYPERTENSION; NONHUMAN; ONCOGENE SRC; PRIORITY JOURNAL; RECEPTOR BINDING; RESTENOSIS; VASCULAR SMOOTH MUSCLE;

ANIMALIA;

EID: 0030799568     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.272.6.c2019     Document Type: Article

References (19)

1. Barone, M. V., and S. Courtneidge. Myc but not Fos rescue of PDGF signalling block caused by kinase inactive Src. Nature 378: 509-512, 1995.
2. Buttke, T. M., J. A. McCubrey, and T. C. Owen. Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines. J. Immunol. Methods 157: 233-240, 1993.
3. Chen, Y. H., J. Pouyssegur, S. A. Courtneidge, and E. Van Obberghen-Schilling. Activation of src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts. J. Biol. Chem. 269: 27372-27377, 1994.
4. Cockcroft, S., and G. M. H. Thomas. Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors. Biochem. J. 288: 1-14, 1992.
5. Daemen, M. J. A. P., D. M. Lombardi, F. T. Bosman, and S. M. Schwartz. Angiotensin II induces smooth muscle cell proliferation in normal and injured rat arterial wall. Circ. Res. 68: 450-456, 1991.
6. Delafontaine, P., M. Brink, and J. Du. Angiotensin II modulation of insulin-like growth factor I expression in the cardiovascular system. Trends Cardiovasc. Med. 6: 187-193, 1996.
7. Dhar, A., and S. D. Shukla. Electrotransjection of pp60c-src monoclonal antibody inhibits activation of phospholipase C in platelets. J. Biol. Chem. 269: 9123-9127, 1994.
8. 2+/calmodulin-sensitive tyrosine kinase. J. Biol. Chem. 271: 14169-14175, 1996.
9. Erpel, T., and S.A. Courtneidge. Src family of protein tyrosine kinases and cellular signal transduction pathways. Curr. Opin. Cell Biol. 7: 176-182, 1995.
10. Fager, G. Thrombin and proliferation of vascular smooth muscle cells. Circ. Res. 77: 645-650, 1995.
11. Guinebault, C., B. Payrastre, C. Sultan, G. Mauco, M. Breton, S. Levy-Tolenado, M. Plantavid, and H. Chap. Tyrosine kinases and phosphoinositide metabolism in thrombin stimulated human platelets. Biochem. J. 292: 851-856, 1993.
12. Hirata, Y., Y. Takagi, Y. Fukaga, and F. Marumo. Endothelin is a potent mitogen for rat vascular smooth muscle cells. Atherosclerosis 78: 225-228, 1989.
13. 2+ entry is blocked by antibodies to phosphatidylinositol 4,5-bisphosphate but does not involve heparin-sensitive inositol 1,4,5-trisphosphate receptors. J. Biol. Chem. 266: 4045-4048, 1991.
14. Huckle, W. R., C. A. Prokop, R. C. Dy, B. Herman, and S. Earp. Angiotensin II stimulates protein-tyrosine phosphorylation in a calcium-dependent manner. Mol. Cell. Biol. 10: 6290-6298, 1990.
15. Huwiler, A., S. Stabel, D. Fabbro, and J. Pfeilschifter. Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists. Biochem. J. 305: 777-784, 1995.
16. Indolfi, C., E. V. Avedimento, A. Rappaciuolo, E. Di Lorenzo, G. Esposito, E. Stabile, A. Feliciello, E. Mele, P. Giulliano, G. Condorelli, and M. Chiariello. Inhibition of ras prevents smooth muscle cell proliferation after vascular injury. Nat. Med. 1: 541-545, 1995.
17. Jawien, A., D. F. Bowen-Pope, V. Lindner, S. M. Schwartz, and A. W. Clowes. Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty. J. Clin. Invest. 89: 507-511, 1992.
18. Linseman, D. A., C. W. Benjamin, and D. A. Jones. Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells. J. Biol. Chem. 270: 12563-12568, 1995.
19. Lyall, F., E. S. Dornan, J. McQueen, F. Boswell, and M. Kelly. Angiotensin II increases protooncogene expression and phosphoinositide turnover in vascular smooth muscle cells via the angiotensin II AT1 receptor. J. Hypertens. 10: 1463-1469, 1992.