Nucleoside triphosphatase and RNA helicase activities associated with GB virus B nonstructural protein 3

Virology

Volumn 261, Issue 2, 1999, Pages 216-226

  Zhong, Weidong ^a   Ingravallo, Paul ^a   Wright Minogue, Jacquelyn ^a   Skelton, Angela ^a   Uss, Annette S ^a   Chase, Robert ^a   Yao, Nanhua ^a   Lau, Johnson Y N ^a   Hong, Zhi ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; DIVALENT CATION; DOUBLE STRANDED RNA; METAL ION; NUCLEOSIDE TRIPHOSPHATASE; POLYNUCLEOTIDE; RECOMBINANT PROTEIN; RNA HELICASE; SERINE PROTEINASE; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SPECIFICITY; HEPATITIS B VIRUS; HEPATITIS G VIRUS; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SEQUENCE HOMOLOGY; SURFACE CHARGE;

ESCHERICHIA COLI; FELIS CATUS; FLAVIVIRIDAE; GB VIRUS C/HEPATITIS G VIRUS; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HEPATITIS GB VIRUS B; RNA VIRUSES; SAGUINUS;

EID: 0033198542     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.9871     Document Type: Article

References (40)

1. Bartenschlager R., Ahlborn-Laake L., Mous J., Jacobsen H. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions. J. Virol. 67:1993;3835-3844.
2. Bazan J. F., Fletterick R. J. Detection of a trypsin-like serine protease domain in flavivirus and pestivirus. Virology. 171:1989;637-639.
3. Deinhardt F., Holmes A. W., Capps R. B., Popper H. Studies on the transmission of human viral hepatitis to marmoset monkeys. I. Transmission of disease, serial passages, and description of liver lesions. J. Exp. Med. 125:1967;673-688.
4. Failla C., Tomei L., De Francesco R. Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins. J. Virol. 68:1994;3753-3760.
5. Grakoui A., McCourt D. W., Wychowski C., Feinstone S. M., Rice C. M. Characterization of the hepatitis C virus-encoded serine proteinase: Determination of the proteinase-dependent polyprotein cleavage sites. J. Virol. 67:1993a;2832-2843.
6. Grakoui A., McCourt D. W., Wychowski C., Feinstone S. M., Rice C. M. A second hepatitis C virus-encoded proteinase. Proc. Natl. Acad. Sci. USA. 90:1993b;10583-10587.
7. Gwack Y., Yoo H., Song I., Choe J., Han J. H. RNA-stimulated ATPase and RNA helicase activities and RNA binding domain of hepatitis G virus nonstructural protein 3. J. Virol. 73:1999;2909-2915.
8. Gwack Y., Kim D. W., Han J. H., Choe J. Characterization of RNA binding activity and RNA helicase activity of the hepatitis C virus NS3 protein. Biochem. Biophys. Res. Commun. 225:1996;654-659.
9. Hijikata M., Mizushima H., Akagi T., Mori S., Kakiuchi N., Kato N., Tanaka T., Kimura K., Shimotohno K. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol. 67:1993;4665-4675.
10. Hong Z., Ferrari E., Wright-Minogue J., Chase R., Risano C., Seelig G., Lee C.-G., Kwong A. D. Enzymatic characterization of hepatitis C virus NS3/4A complexes expressed in mammalian cells using the herpes simplex virus amplicon system. J. Virol. 70:1996;4261-4268.
11. Houghton M. Hepatitis C viruses. Fields B. N., Knipe D. M., Howley P. M. Virology. 1996;1035-1058 Raven Press, New York.
12. Jin L., Peterson D. L. Expression, isolation, and characterization of the hepatitis C virus ATPase/RNA helicase. Arch. Biochem. Biophys. 323:1995;47-53.
13. Kani A., Tanabe K., Kohara M. Poly(U) binding activity of hepatitis C virus NS3 protein, a putative RNA helicase. FEBS Lett. 376:1995;221-224.
14. Kim D. W., Gwack Y., Han J. H., Choe J. C-terminal domain of the hepatitis C virus NS3 protein contains an RNA helicase activity. Biochem. Biophys. Res. Commun. 215:1995;160-166.
15. Kim D. W., Kim J., Gwack Y., Han J. H., Choe J. Mutational analysis of the hepatitis C virus RNA helicase. J. Virol. 71:1997;9400-9409.
16. Kim J. L., Morgenstern K. A., Griffith J. P., Dwyer M. D., Thomson J. A., Murcko M. A., Lin C., Caron P. R. Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: The crystal structure provides insights into the mode of unwinding. Structure. 6:1998;89-100.
17. Kim J. L., Morgenstern K. A., Lin C., Fox T., Dwyer M. D., Landro J. A., Chambers S. P., Markland W., Lepre C. A., O'Malley E. T., Harbeson S. L., Rice C. M., Murcko M. A., Caron P. R., Thomson J. A. Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell. 87:1996;343-355.
18. Koonin E. V., Dolja V. V. Evolution and taxonomy of positive-strand RNA viruses: Implications of comparative analysis of amino acid sequences. Crit. Rev. Biochem. Mol. Biol. 28:1993;375-430.
19. Laxton C. D., McMillan D., Sullivan V., Ackrill A. M. Expression and characterization of the hepatitis G virus helicase. J. Virol. Hepat. 5:1998;21-26.
20. Lee C.-G., Hurwitz J. A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3′ to 5′ direction. J. Biol. Chem. 267:1992;4398-4407.
21. Lin C., Pragai B. M., Grakoui A., Xu J., Rice C. M. Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics. J. Virol. 68:1994;8147-8157.
22. Morgenstern K. A., Landro J. A., Hsiao K., Lin C., Gu Y., Su M. S., Thomson J. A. Polynucleotide modulation of the protease, nucleoside triphosphatase, and helicase activities of a hepatitis C virus NS3-NS4A complex isolated from transfected COS cells. J. Virol. 71:1997;3767-3775.
23. Muerhoff A. S., Leary T. P., Simons J. N., Pilot-Matias T. J., Dawson G. J., Erker J. C., Chalmers M. L., Schlauder G. G., Desai S. M., Mushahwar I. K. Genomic organization of GB viruses A and B: Two new members of the Flaviviridae associated with GB agent hepatitis. J. Virol. 69:1995;5621-5630.
24. Nicholls, A. 1993, GRASP: Graphical Representation and Analysis of Surface Properties, Columbia University, New York.
25. Ohba K., Mizokami M., Lau J. Y., Orito E., Ikeo K., Gojobori T. Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents. FEBS Lett. 378:1996;232-234.
26. Parks W. P., Melnick J. L. Attempted isolation of hepatitis viruses in marmosets. J. Infect. Dis. 120:1969;539-547.
27. Parks W. P., Melnick J. L., Voss W. R., Singer D. B., Rosenberg H. S., Alcott J., Casazza A. M. Characterization of marmoset hepatitis virus. J. Infect. Dis. 120:1969;548-559.
28. Rice C. M. Flaviviridae: The viruses and their replication. Fields B. N., Knipe D. M., Howley P. M. Virology. 1996;931-960 Raven Press, New York.
29. Scarselli E., Urbani A., Sbardellati A., Tomei L., De Francesco R., Traboni C. GB virus B and hepatitis C virus NS3 serine proteases share substrate specificity. J. Virol. 71:1997;4985-4989.
30. Schaluder G. G., Dawson G. J., Simons J. N., Pilot-Matias T. J., Gutierrez R. A., Heynen C. A., Knigge M. F., Kurpiewski G. S., Buijk S. L., Leary T. P., Muerhoff A. S., Desai S. M., Mushahwar I. K. Molecular and serologic analysis in the transmission of the GB hepatitis agents. J. Med. Virol. 46:1995a;81-90.
31. Schlauder G. G., Pilot-Matias T. J., Gabriel G. S., Simons J. N., Muerhoff A. S., Dawson G. J., Mushahwar I. K. Origin of GB-hepatitis viruses. Lancet. 346:1995b;447-448.
32. Simons J. N., Pilot-Matias T. J., Leary T. P., Dawson G. J., Desai S. M., Schlauder G. G., Muerhoff A. S., Erker J. C., Buijk S. L., Chalmers M. L., Van Sant C. L., Mushahwar I. K. Identification of two flavivirus-like genomes in the GB hepatitis agent. Proc. Natl. Acad. Sci. USA. 92:1995;3401-3405.
33. Suzich J. A., Tamura J. K., Palmer-Hill F., Warrener P., Grakoui A., Rice C. M., Feinstone S. M., Collett M. S. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes. J. Virol. 67:1993;6152-6158.
34. Tai C. L., Chi W. K., Chen D. S., Hwang L. H. The helicase activity associated with hepatitis C virus nonstructural protein 3. J. Virol. 70:1996;8477-8484.
35. Tamura J. K., Warrener P., Collett M. S. RNA-stimulated NTPase activity associated with the p80 protein of the pestivirus bovine viral diarrhea virus. Virology. 193:1993;1-10.
36. Tan B.-H., Fu J., Sugrue R. J., Yap E.-H., Chan Y.-C., Tan Y. H. Recombinant Dengue type 1 NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity. Virology. 216:1996;317-325.
37. Tomei L., Failla C., Santolini E., de Francesco R., La Monica N. NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J. Virol. 67:1993;4017-4026.
38. Warrener P., Collett M. Pestivirus NS3 (p80) protein possesses RNA helicase activity. J. Virol. 69:1995;1720-1726.
39. Yao N., Hesson T., Cable M., Hong Z., Kwong A. D., Le H. V., Weber P. C. Structure of the hepatitis C virus RNA helicase domain. Nat. Struct. Biol. 4:1997;463-467.
40. Zuckermann A. J. The new GB hepatitis viruses. Lancet. 345:1995;1453-1454.