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Volumn 291, Issue 6, 2006, Pages

Glucose-dependent expansion of pancreatic β-cells by the protein p8 in vitro and in vivo

Author keywords

cell proliferation; Diabetes; Insulin secretion; Islet transplantation

Indexed keywords

AMYLIN; C PEPTIDE; GLUCOKINASE; GLUCOSE; GLUCOSE TRANSPORTER 2; ISOPROPYL THIOGALACTOSIDE; PROINSULIN; PROINSULIN I; PROTEIN P8; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR PDX 1;

EID: 33845445950     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00436.2005     Document Type: Article
Times cited : (20)

References (45)
  • 1
    • 0024508097 scopus 로고
    • Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion
    • Bonner-Weir S, Deery D, Leahy JL, and Weir GC. Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 38: 49-53, 1989.
    • (1989) Diabetes , vol.38 , pp. 49-53
    • Bonner-Weir, S.1    Deery, D.2    Leahy, J.L.3    Weir, G.C.4
  • 3
    • 0032433541 scopus 로고    scopus 로고
    • Assessment of intracellular insulin content during all steps of human islet isolation procedure
    • Brandhorst H, Brandhorst D, Brendel MD, Hering BJ, and Bretzel RG. Assessment of intracellular insulin content during all steps of human islet isolation procedure. Cell Transplant 7: 489-495, 1998.
    • (1998) Cell Transplant , vol.7 , pp. 489-495
    • Brandhorst, H.1    Brandhorst, D.2    Brendel, M.D.3    Hering, B.J.4    Bretzel, R.G.5
  • 5
    • 0035489990 scopus 로고    scopus 로고
    • Protein kinase C-zeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation
    • Buteau J, Foisy S, Rhodes CJ, Carpenter L, Biden TJ, and Prentki M. Protein kinase C-zeta activation mediates glucagon-like peptide-1-induced pancreatic beta-cell proliferation. Diabetes 50: 2237-2243, 2001.
    • (2001) Diabetes , vol.50 , pp. 2237-2243
    • Buteau, J.1    Foisy, S.2    Rhodes, C.J.3    Carpenter, L.4    Biden, T.J.5    Prentki, M.6
  • 7
    • 0031007661 scopus 로고    scopus 로고
    • Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells
    • Carty MD, Lillquist JS, Peshavaria M, Stein R, and Soeller WC. Identification of cis- and trans-active factors regulating human islet amyloid polypeptide gene expression in pancreatic beta-cells. J Biol Chem 272: 11986-11993, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 11986-11993
    • Carty, M.D.1    Lillquist, J.S.2    Peshavaria, M.3    Stein, R.4    Soeller, W.C.5
  • 8
    • 1642618179 scopus 로고    scopus 로고
    • Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: Signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling
    • Cousin SP, Hugl SR, Myers MG Jr, White MF, Reifel-Miller A, and Rhodes CJ. Stimulation of pancreatic beta-cell proliferation by growth hormone is glucose-dependent: signal transduction via janus kinase 2 (JAK2)/signal transducer and activator of transcription 5 (STAT5) with no crosstalk to insulin receptor substrate-mediated mitogenic signalling. Biochem J 344: 649-658, 1999.
    • (1999) Biochem J , vol.344 , pp. 649-658
    • Cousin, S.P.1    Hugl, S.R.2    Myers Jr., M.G.3    White, M.F.4    Reifel-Miller, A.5    Rhodes, C.J.6
  • 9
    • 0035877778 scopus 로고    scopus 로고
    • Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1)
    • Dickson LM, Lingohr MK, McCuaig J, Hugl SR, Snow L, Kahn BB, Myers MG Jr, and Rhodes CJ. Differential activation of protein kinase B and p70(S6)K by glucose and insulin-like growth factor 1 in pancreatic beta-cells (INS-1). J Biol Chem 276: 21110-21120, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 21110-21120
    • Dickson, L.M.1    Lingohr, M.K.2    McCuaig, J.3    Hugl, S.R.4    Snow, L.5    Kahn, B.B.6    Myers Jr., M.G.7    Rhodes, C.J.8
  • 10
    • 3242656480 scopus 로고    scopus 로고
    • Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: A role for protein kinase B in the Akt?
    • Dickson LM and Rhodes CJ. Pancreatic beta-cell growth and survival in the onset of type 2 diabetes: a role for protein kinase B in the Akt? Am J Physiol Endocrinol Metab 287: E192-E198, 2004.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Dickson, L.M.1    Rhodes, C.J.2
  • 11
    • 1642546212 scopus 로고    scopus 로고
    • Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: Modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR)
    • Diraison F, Parton L, Ferre P, Foufelle F, Briscoe CP, Leclerc I, and Rutter GA. Over-expression of sterol-regulatory-element-binding protein-1c (SREBP1c) in rat pancreatic islets induces lipogenesis and decreases glucose-stimulated insulin release: modulation by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). Biochem J 378: 769-778, 2004.
    • (2004) Biochem J , vol.378 , pp. 769-778
    • Diraison, F.1    Parton, L.2    Ferre, P.3    Foufelle, F.4    Briscoe, C.P.5    Leclerc, I.6    Rutter, G.A.7
  • 12
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y, Brown J, Martinez OI, and Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 429: 41-46, 2004.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 13
    • 24144457224 scopus 로고    scopus 로고
    • XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes
    • Emamaullee JA, Rajotte RV, Liston P, Korneluk RG, Lakey JR, Shapiro AM, and Elliott JF. XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes. Diabetes 54: 2541-2548, 2005.
    • (2005) Diabetes , vol.54 , pp. 2541-2548
    • Emamaullee, J.A.1    Rajotte, R.V.2    Liston, P.3    Korneluk, R.G.4    Lakey, J.R.5    Shapiro, A.M.6    Elliott, J.F.7
  • 15
    • 0036238957 scopus 로고    scopus 로고
    • Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations
    • Gahr S, Merger M, Bollheimer LC, Hammerschmied CG, Scholmerich J, and Hugl SR. Hepatocyte growth factor stimulates proliferation of pancreatic beta-cells particularly in the presence of subphysiological glucose concentrations. J Mol Endocrinol 28: 99-110, 2002.
    • (2002) J Mol Endocrinol , vol.28 , pp. 99-110
    • Gahr, S.1    Merger, M.2    Bollheimer, L.C.3    Hammerschmied, C.G.4    Scholmerich, J.5    Hugl, S.R.6
  • 16
    • 0035397489 scopus 로고    scopus 로고
    • Transforming growth factor beta-1 enhances Smad transcriptional activity through activation of p8 gene expression
    • Garcia-Montero AC, Vasseur S, Giono LE, Canepa E, Moreno S, Dagorn JC, and Iovanna JL. Transforming growth factor beta-1 enhances Smad transcriptional activity through activation of p8 gene expression. Biochem J 357: 249-253, 2001.
    • (2001) Biochem J , vol.357 , pp. 249-253
    • Garcia-Montero, A.C.1    Vasseur, S.2    Giono, L.E.3    Canepa, E.4    Moreno, S.5    Dagorn, J.C.6    Iovanna, J.L.7
  • 17
    • 9644266753 scopus 로고    scopus 로고
    • Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass
    • Georgia S and Bhushan A. Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass. J Clin Invest 114: 963-968, 2004.
    • (2004) J Clin Invest , vol.114 , pp. 963-968
    • Georgia, S.1    Bhushan, A.2
  • 18
    • 0037107396 scopus 로고    scopus 로고
    • Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy
    • Goruppi S, Bonventre JV, and Kyriakis JM. Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy. EMBO J 21: 5427-5436, 2002.
    • (2002) EMBO J , vol.21 , pp. 5427-5436
    • Goruppi, S.1    Bonventre, J.V.2    Kyriakis, J.M.3
  • 19
    • 2442675146 scopus 로고    scopus 로고
    • The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypertrophy require NFAT4
    • Goruppi S and Kyriakis JM. The pro-hypertrophic basic helix-loop-helix protein p8 is degraded by the ubiquitin/proteasome system in a protein kinase B/Akt- and glycogen synthase kinase-3-dependent manner, whereas endothelin induction of p8 mRNA and renal mesangial cell hypertrophy require NFAT4. J Biol Chem 279: 20950-20958, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 20950-20958
    • Goruppi, S.1    Kyriakis, J.M.2
  • 20
    • 0032504211 scopus 로고    scopus 로고
    • Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells
    • Hugl SR, White MF, and Rhodes CJ. Insulin-like growth factor I (IGF-I)-stimulated pancreatic beta-cell growth is glucose-dependent. Synergistic activation of insulin receptor substrate-mediated signal transduction pathways by glucose and IGF-I in INS-1 cells. J Biol Chem 273: 17771-17779, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 17771-17779
    • Hugl, S.R.1    White, M.F.2    Rhodes, C.J.3
  • 22
    • 1842292177 scopus 로고    scopus 로고
    • Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47
    • Lu M, Seufert J, and Habener JF. Pancreatic beta-cell-specific repression of insulin gene transcription by CCAAT/enhancer-binding protein beta. Inhibitory interactions with basic helix-loop-helix transcription factor E47. J Biol Chem 272: 28349-28359, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 28349-28359
    • Lu, M.1    Seufert, J.2    Habener, J.F.3
  • 24
    • 2942617091 scopus 로고    scopus 로고
    • p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth
    • Malicet C, Lesavre N, Vasseur S, and Iovanna JL. p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth. Mol Cancer 2: 37, 2003.
    • (2003) Mol Cancer , vol.2 , pp. 37
    • Malicet, C.1    Lesavre, N.2    Vasseur, S.3    Iovanna, J.L.4
  • 25
    • 0031465799 scopus 로고    scopus 로고
    • Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth
    • Mallo GV, Fiedler F, Calvo EL, Ortiz EM, Vasseur S, Keim V, Morisset J, and Iovanna JL. Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth. J Biol Chem 272: 32360-32369, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 32360-32369
    • Mallo, G.V.1    Fiedler, F.2    Calvo, E.L.3    Ortiz, E.M.4    Vasseur, S.5    Keim, V.6    Morisset, J.7    Iovanna, J.L.8
  • 26
    • 5044234185 scopus 로고    scopus 로고
    • Reexpression of p8 contributes to tumorigenic properties of pituitary cells and appears in a subset of prolactinomas in transgenic mice that hypersecrete luteinizing hormone
    • Mohammad HP, Seachrist DD, Quirk CC, and Nilson JH. Reexpression of p8 contributes to tumorigenic properties of pituitary cells and appears in a subset of prolactinomas in transgenic mice that hypersecrete luteinizing hormone. Mol Endocrinol 18: 2583-2593, 2004.
    • (2004) Mol Endocrinol , vol.18 , pp. 2583-2593
    • Mohammad, H.P.1    Seachrist, D.D.2    Quirk, C.C.3    Nilson, J.H.4
  • 28
    • 0347360186 scopus 로고    scopus 로고
    • Pharmacology of exenatide (synthetic exendin-4): A potential therapeutic for improved glycemic control of type 2 diabetes
    • Nielsen LL, Young AA, and Parkes DG. Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes. Regul Pept 117: 77-88, 2004.
    • (2004) Regul Pept , vol.117 , pp. 77-88
    • Nielsen, L.L.1    Young, A.A.2    Parkes, D.G.3
  • 29
    • 0027384997 scopus 로고
    • IPF1, a homeodomain-containing transactivator of the insulin gene
    • Ohlsson H, Karlsson K, and Edlund T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J 12: 4251-4259, 1993.
    • (1993) EMBO J , vol.12 , pp. 4251-4259
    • Ohlsson, H.1    Karlsson, K.2    Edlund, T.3
  • 30
    • 0038522555 scopus 로고    scopus 로고
    • Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats
    • Paris M, Bernard-Kargar C, Berthault MF, Bouwens L, and Ktorza A. Specific and combined effects of insulin and glucose on functional pancreatic beta-cell mass in vivo in adult rats. Endocrinology 144: 2717-2727, 2003.
    • (2003) Endocrinology , vol.144 , pp. 2717-2727
    • Paris, M.1    Bernard-Kargar, C.2    Berthault, M.F.3    Bouwens, L.4    Ktorza, A.5
  • 31
    • 0842263986 scopus 로고    scopus 로고
    • Nuclear protein p8 is associated with glucose-induced pancreatic beta-cell growth
    • Path G, Opel A, Knoll A, and Seufert J. Nuclear protein p8 is associated with glucose-induced pancreatic beta-cell growth. Diabetes 53, Suppl 1: S82-S85, 2004.
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 1
    • Path, G.1    Opel, A.2    Knoll, A.3    Seufert, J.4
  • 34
    • 0032103208 scopus 로고    scopus 로고
    • Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus
    • Seufert J, Weir GC, and Habener JF. Differential expression of the insulin gene transcriptional repressor CCAAT/enhancer-binding protein beta and transactivator islet duodenum homeobox-1 in rat pancreatic beta cells during the development of diabetes mellitus. J Clin Invest 101: 2528-2539, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 2528-2539
    • Seufert, J.1    Weir, G.C.2    Habener, J.F.3
  • 37
    • 21344433221 scopus 로고    scopus 로고
    • Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
    • Taieb D, Malicet C, Garcia S, Rocchi P, Arnaud C, Dagorn JC, Iovanna JL, and Vasseur S. Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity. Hepatology 42: 176-182, 2005.
    • (2005) Hepatology , vol.42 , pp. 176-182
    • Taieb, D.1    Malicet, C.2    Garcia, S.3    Rocchi, P.4    Arnaud, C.5    Dagorn, J.C.6    Iovanna, J.L.7    Vasseur, S.8
  • 38
    • 1342304085 scopus 로고    scopus 로고
    • p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I
    • Vasseur S, Folch-Puy E, Hlouschek V, Garcia S, Fiedler F, Lerch MM, Dagorn JC, Closa D, and Iovanna JL. p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I. J Biol Chem 279: 7199-7207, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 7199-7207
    • Vasseur, S.1    Folch-Puy, E.2    Hlouschek, V.3    Garcia, S.4    Fiedler, F.5    Lerch, M.M.6    Dagorn, J.C.7    Closa, D.8    Iovanna, J.L.9
  • 42
    • 0030457705 scopus 로고    scopus 로고
    • Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor
    • Waeber G, Thompson N, Nicod P, and Bonny C. Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor. Mol Endocrinol 10: 1327-1334, 1996.
    • (1996) Mol Endocrinol , vol.10 , pp. 1327-1334
    • Waeber, G.1    Thompson, N.2    Nicod, P.3    Bonny, C.4
  • 43
    • 0029909387 scopus 로고    scopus 로고
    • The human glucokinase gene beta-cell-type promoter: An essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells
    • Watada H, Kajimoto Y, Umayahara Y, Matsuoka T, Kaneto H, Fujitani Y, Kamada T, Kawamori R, and Yamasaki Y. The human glucokinase gene beta-cell-type promoter: an essential role of insulin promoter factor 1/PDX-1 in its activation in HIT-T15 cells. Diabetes 45: 1478-1488, 1996.
    • (1996) Diabetes , vol.45 , pp. 1478-1488
    • Watada, H.1    Kajimoto, Y.2    Umayahara, Y.3    Matsuoka, T.4    Kaneto, H.5    Fujitani, Y.6    Kamada, T.7    Kawamori, R.8    Yamasaki, Y.9
  • 45
    • 0035119871 scopus 로고    scopus 로고
    • Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes
    • Zulewski H, Abraham EJ, Gerlach MJ, Daniel PB, Moritz W, Muller B, Vallejo M, Thomas MK, and Habener JF. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. Diabetes 50: 521-533, 2001.
    • (2001) Diabetes , vol.50 , pp. 521-533
    • Zulewski, H.1    Abraham, E.J.2    Gerlach, M.J.3    Daniel, P.B.4    Moritz, W.5    Muller, B.6    Vallejo, M.7    Thomas, M.K.8    Habener, J.F.9


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