Transforming growth factor β-1 enhances Smad transcriptional activity through activation of p8 gene expression

Biochemical Journal

Volumn 357, Issue 1, 2001, Pages 249-253

  Garcia Montero A C ^a   Vasseur, S ^a   Giono, L E ^a   Canepa, E ^a   Moreno, S ^a   Dagorn, J C ^a   Iovanna, J L ^a  

^a INSERM   (France)

Author keywords

Fibroblasts; Mouse; TGF 1

Indexed keywords

CELLS; GENETIC ENGINEERING; GROWTH KINETICS; RNA;

FIBROBLASTS;

BIOCHEMISTRY;

SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL GROWTH; EMBRYO DEVELOPMENT; EXTRACELLULAR MATRIX; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE TARGETING; MEDIATOR RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

3T3 CELLS; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELLS, CULTURED; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA; DNA-BINDING PROTEINS; EMBRYO; FIBROBLASTS; GENE DELETION; GENE EXPRESSION REGULATION; GENES, REPORTER; GROWTH SUBSTANCES; HIGH MOBILITY GROUP PROTEINS; HOMOZYGOTE; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOPLASM PROTEINS; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; THYMIDINE; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; EUKARYOTA;

EID: 0035397489     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3570249     Document Type: Article

References (31)

1. Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth
2. Lipopolysaccharides induce p8 mRNA expression in vivo and in vitro
3. Expression of a novel factor in human breast cancer cells with metastatic potential
4. Cloning and expression of the human p8, a nuclear protein with mitogenic activity
5. Human p8 is a HMG-I/Y-like protein with DNA binding activity enhanced by phosphorylation
6. The transforming growth factor-beta family
7. TGF-beta stimulation and inhibition of cell proliferation: New mechanistic insights
8. Transforming growth factor beta 1 inhibits mouse keratinocytes late in G1 independent of effects on gene transcription
9. Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta)
10. TGF-beta signal transduction
11. Transcriptional control by the TGF-beta/Smad signaling system
12. Regulation of Smad activity
13. Structural and functional characterization of the mouse p8 gene: Promotion of transcription by the CAAT-enhancer binding protein α (C/EBPα) and C/EBPβ trans-acting factors involves a C/EBP cis-acting element and other regions of the promoter
14. A simple phase-extraction assay for chloramphenicol acyltransferase activity
15. Pancreatitis-associated protein I (PAP I), an acute phase protein induced by cytokines. Identification of two functional interleukin-6 response elements in the rat PAP I promoter region
16. Selective loss of cone tunction in mice lacking the cyclic nucleotide-gated channel CNG3
17. In vitro growth characteristics of embryo fibroblasts isolated trom p53-deficient mice
18. Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer
19. Phosphorylation of rat serine 105 or mouse threonine 217 in C/EBP β is required for hepatocyte proliferation induced by TGF α
20. CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor β signaling in monocyte development
21. TGF-beta induces bimodal proliferation of connective tissue cells via complex control of an autocrine PDGF loop
22. TGF-β signalling from cell membrane to nucleus through SMAD proteins
23. Transforming growth factor beta stimulates mammary adenocarcinoma cell invasion and metastatic potential
24. A soluble transforming growth factor beta type III receptor suppresses tumorigenicity and metastasis of human breast cancer MDA-MB-231 cells
25. TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells
26. The role of high-mobility group I(Y) proteins in expression of IL-2 and T cell proliferation
27. Specific binding of high-mobility-group I (HMGI) protein and histone H1 to the upstream AT-rich region of the murine beta interferon promoter: HMGI protein acts as a potential antirepressor of the promoter
28. A role for the architectural transcription factors HMGI(Y) in cytokine gene transcription in T cells
29. NF-κB mediated transcriptional activation is enhanced by the architectural factor HMGI-C
30. High mobility group I proteins interfere with the homeodomains binding to DNA
31. HMGI(Y) andSp1 in addition to NF-κB regulate transcription of the MGSA/GRO α gene