Overexpression of p8 is inversely correlated with apoptosis in pancreatic cancer

Clinical Cancer Research

Volumn 7, Issue 5, 2001, Pages 1320-1324

  Su, Shi Bing ^a   Motoo, Yoshiharu ^a   Iovanna, Juan Lucio ^b   Berthézène, Patrice ^b   Xie, Min Jue ^a   Mouri, Hisatsugu ^a   Ohtsubo, Koushiro ^a   Matsubara, Fujitsugu ^c   Sawabu, Norio ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b INSERM   (France)

^c Tatsunokuchi Houju General Hospital   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; CELL PROTEIN; PROTEIN P8; SINGLE STRANDED DNA; UNCLASSIFIED DRUG;

ADULT; AGED; APOPTOSIS; ARTICLE; CANCER GROWTH; CHROMOSOME 16P; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION FUNCTION; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AGED; AGED, 80 AND OVER; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BISBENZIMIDE; DNA, NEOPLASM; DNA, SINGLE-STRANDED; DNA-BINDING PROTEINS; FEMALE; FLUORESCENT DYES; GENE EXPRESSION; GROWTH SUBSTANCES; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; SURVIVAL ANALYSIS;

EID: 0034895893     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Apoptosis. A basic biological phenomenon with wide ranging implications in tissue kinetics
2. Cell death via apoptosis and its relationship to growth, development, and differentiation of both tumour and normal cells
3. Proliferative activity and p53 protein accumulation correlate with early invasive trend, and apoptosis correlates with differentiation grade in oesophageal squamous cell carcinomas
4. Apoptosis and proliferation in gastric carcinoma: The association with histological type
5. Detection of apoptotic cells in human colorectal cancer by two different in situ methods: Antibody against single-stranded DNA and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling (TUNEL) mehods
6. Apoptotic index and apoptosis influencing proteins bcl-2, mcl-1, bax and caspases 3, 6, and 8 in pancreatic carcinoma
7. Spontaneous apoptosis and proliferation in human pancreatic cancer
8. Cloning and expression of the rat p8 cDNA, a new gene activated in pancreas during the acute phase of pancreatitis, pancreatic development, and regeneration, and which promotes cellular growth
9. Cloning and expression of the human p8, a nuclear protein with mitogenic activity
10. Structural and functional characterization of the mouse p8 gene: Promotion of transcription by the CAAT-enhancer binding protein α(C/EBPα) and C/EBPβ trans-acting factors involves a C/EBP cis-acting element and other regions of the promoter
11. Expression of p8 in human pancreatic cancer
12. Apoptosis in breast carcinomas detected with monoclonal antibody to single-stranded DNA: Relation to bcl-2 expression, hormone receptors, and lymph node metastases
13. Mechanisms of cell death after pancreatic duct obstruction in the opossum and the rat
14. Pancreatic nonendocrine tumors
15. Importance of pathologic staging in the surgical management of adenocarcinoma of the exocrine pancreas
16. Monoclonal antibody to single-stranded DNA is a specific and sensitive cellular marker of apoptosis
17. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note
18. Human pancreatic adenocarcinomas express Fas and Fas ligand, yet are resistant to Fas-mediated apoptosis
19. Fas ligand is frequently expressed in human pancreatic duct cell carcinoma
20. Bcl-2 expression related to altered p53 protein and its impact on the progression of human pancreatic carcinoma
21. Bax, but not bcl-2, influences the prognosis of human pancreatic cancer
22. Moderate activation of the apoptosis inhibitor bcl-xL worsens the prognosis in pancreatic cancer
23. The protective effects of L-arginine after liver ischaemia/reperfusion injury in a pig model
24. Angiogenesis: New insights and therapeutic potential