Disposition of flavonoids via enteric recycling: Structural effects and lack of correlations between in vitro and in situ metabolic properties

Drug Metabolism and Disposition

Volumn 34, Issue 11, 2006, Pages 1837-1848

  Wang, Stephen W J ^a   Chen, Jun ^a,b   Jia, Xiaobin ^a   Tam, Vincent H ^a   Hu, Ming ^a  

^a UNIVERSITY OF HOUSTON   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHANIN A; DAIDZEIN; FLAVONOID; FORMONONETIN; GENISTEIN; GLUCURONIDE; GLYCITEIN; ISOFLAVONE DERIVATIVE; PRUNETIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; COLON; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG EXCRETION; DRUG METABOLISM; DUODENUM; ENZYME KINETICS; GLUCURONIDATION; ILEUM; IN VITRO STUDY; INTESTINE PERFUSION; LIVER MICROSOME; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SMALL INTESTINE;

ANIMALS; INTESTINAL ABSORPTION; INTESTINES; ISOFLAVONES; MALE; METABOLIC CLEARANCE RATE; MICROSOMES; MICROSOMES, LIVER; PERFUSION; PREDICTIVE VALUE OF TESTS; RATS; RATS, INBRED STRAINS; STRUCTURE-ACTIVITY RELATIONSHIP; TISSUE DISTRIBUTION;

EID: 33751113603     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.009910     Document Type: Article

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