-
1
-
-
9044239673
-
AG337, a novel lipophilic thymidylate synthase inhibitor: In vitro and in vivo preclinical studies
-
Webber, S.; Bartlett, C. A.; Boritzki, T. J.; Hilliard, J. A.; Howland, E. F.; Johnston, A. L.; Kosa, M.; Margosiak, S. A.; Morse, C. A.; Shetty, B. V. AG337, a novel lipophilic thymidylate synthase inhibitor: In vitro and in vivo preclinical studies. Cancer Chemother. Pharmacol. 1996, 37 (6), p 509-17.
-
(1996)
Cancer Chemother. Pharmacol.
, vol.37
, Issue.6
, pp. 509-517
-
-
Webber, S.1
Bartlett, C.A.2
Boritzki, T.J.3
Hilliard, J.A.4
Howland, E.F.5
Johnston, A.L.6
Kosa, M.7
Margosiak, S.A.8
Morse, C.A.9
Shetty, B.V.10
-
2
-
-
0009652281
-
Phase II trials of Thymitag (AG337) in six solid tumor diseases
-
Abstract #296
-
Clendeninn, N. J.; Johnston, A. Phase II trials of Thymitag (AG337) in six solid tumor diseases. Proc. Am. Assoc. Cancer Res. 1996, 37, 86 (Abstract #296).
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
, pp. 86
-
-
Clendeninn, N.J.1
Johnston, A.2
-
3
-
-
0000627433
-
A phase I clinical study of the novel antifolate AG337 given by 5 day oral administration
-
Abstract #293
-
Rafi, I.; Boddy, A. V.; Talor, G. A.; Calvete, J. A.; Bailey, N. B.; Lind, M. J.; Newell, D. R.; Calvert, A. H.; Johnston, A.; Clendeninn, N. J. A phase I clinical study of the novel antifolate AG337 given by 5 day oral administration. Proc. Am. Assoc. Cancer Res. 1996, 37, 86 (Abstract #293).
-
(1996)
Proc. Am. Assoc. Cancer Res.
, vol.37
, pp. 86
-
-
Rafi, I.1
Boddy, A.V.2
Talor, G.A.3
Calvete, J.A.4
Bailey, N.B.5
Lind, M.J.6
Newell, D.R.7
Calvert, A.H.8
Johnston, A.9
Clendeninn, N.J.10
-
4
-
-
0023924860
-
Membrane permeability parameters for some amino acids and β-lactam antibiotics: Application of boundary layer approach
-
Hu, M.; Sinko, P. J.; deMeere, A. L. J.; Johnson, D. A.; Amidon, G. L. Membrane permeability parameters for some amino acids and β-lactam antibiotics: Application of boundary layer approach. J. Theor. Biol. 1988, 131, 107-114.
-
(1988)
J. Theor. Biol.
, vol.131
, pp. 107-114
-
-
Hu, M.1
Sinko, P.J.2
DeMeere, A.L.J.3
Johnson, D.A.4
Amidon, G.L.5
-
5
-
-
0027988025
-
Comparison of L- and D-methionine transport in a cultured intestinal epithelial model and a perfused rat intestinal model
-
Zheng, L.; Chen, J.; Zhu, Y.; Yang, H.; Elmquist, W.; Hu, M. Comparison of L-and D-methionine transport in a cultured intestinal epithelial model and a perfused rat intestinal model. Pharm. Res. 1994, 11, 1771-1776.
-
(1994)
Pharm. Res.
, vol.11
, pp. 1771-1776
-
-
Zheng, L.1
Chen, J.2
Zhu, Y.3
Yang, H.4
Elmquist, W.5
Hu, M.6
-
6
-
-
0023715382
-
Estimating human oral fraction dose absorbed: A correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds
-
Amidon, G. L.; Sinko, P. J.; Fleisher, D. Estimating human oral fraction dose absorbed: A correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds. Pharm. Res. 1988, 5, 651-654.
-
(1988)
Pharm. Res.
, vol.5
, pp. 651-654
-
-
Amidon, G.L.1
Sinko, P.J.2
Fleisher, D.3
-
7
-
-
77957077456
-
Permeation of nucleosides, nucleic acid bases, and nucleotides in animal cells
-
Plagemann, P. G. W.; Wohlhueter, R. M. Permeation of nucleosides, nucleic acid bases, and nucleotides in animal cells. Curr. Top. Membr. Transport 1980, 14, 225-330.
-
(1980)
Curr. Top. Membr. Transport
, vol.14
, pp. 225-330
-
-
Plagemann, P.G.W.1
Wohlhueter, R.M.2
-
8
-
-
0023751603
-
Nucleoside and nucleobase transport in animal cells
-
Plagemann, P. G. W.; Wohlhueter, R. M.; Clive Woffendin, Nucleoside and nucleobase transport in animal cells. Biochim. Biophys. Acta 1988, 947, 405-443.
-
(1988)
Biochim. Biophys. Acta
, vol.947
, pp. 405-443
-
-
Plagemann, P.G.W.1
Wohlhueter, R.M.2
Woffendin, C.3
-
9
-
-
0015160590
-
Intestinal transport of dipeptides in man: Relative importance of hydrolysis and absorption
-
Adibi, S. A.; Morse, E. L. Intestinal transport of dipeptides in man: relative importance of hydrolysis and absorption. J. Clin. Invest. 1971, 50, 2266-2275.
-
(1971)
J. Clin. Invest.
, vol.50
, pp. 2266-2275
-
-
Adibi, S.A.1
Morse, E.L.2
-
10
-
-
0016254128
-
Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum
-
Krag, E.; Philips, S. F. Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum. J. Clin. Invest. 1974, 53, 1686-1694.
-
(1974)
J. Clin. Invest.
, vol.53
, pp. 1686-1694
-
-
Krag, E.1
Philips, S.F.2
-
11
-
-
0002878914
-
Intestinal absorption of amino acids
-
Johnson, L. R., Ed.; Raven Press: New York
-
Munck, B. G. Intestinal absorption of amino acids, In Physiology of Gastrointestinal Tract; Johnson, L. R., Ed.; Raven Press: New York, 1981; pp 1097-1022.
-
(1981)
Physiology of Gastrointestinal Tract
, pp. 1097-11022
-
-
Munck, B.G.1
-
12
-
-
0025912322
-
Active hexose transport across cultured human Caco-2 cells: Characterization and influence of culture conditions
-
Riley, S. A.; Warhurst, G.; Crowe, P. T.; Turnberg, L. A. Active hexose transport across cultured human Caco-2 cells: characterization and influence of culture conditions. Biochim. Biophys. Acta, 1991, 1066, 175-182.
-
(1991)
Biochim. Biophys. Acta
, vol.1066
, pp. 175-182
-
-
Riley, S.A.1
Warhurst, G.2
Crowe, P.T.3
Turnberg, L.A.4
-
14
-
-
0027317898
-
pH-dependent transepithelial transport of cephalexin in rabbit intestinal mucosa
-
Hidalgo, I. J.; Ryan, F. M.; Marks, G. J.; Smith, P. L. pH-dependent transepithelial transport of cephalexin in rabbit intestinal mucosa. Int. J. Pharm. 1993, 98, 83-92.
-
(1993)
Int. J. Pharm.
, vol.98
, pp. 83-92
-
-
Hidalgo, I.J.1
Ryan, F.M.2
Marks, G.J.3
Smith, P.L.4
-
15
-
-
0025668535
-
Mechanism of L-α-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2)
-
Hu, M.; Borchardt, R. T. Mechanism of L-α-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2). Pharm. Res. 1990, 7, 1313-1319.
-
(1990)
Pharm. Res.
, vol.7
, pp. 1313-1319
-
-
Hu, M.1
Borchardt, R.T.2
-
16
-
-
0027422902
-
Comparison of Uptake Characteristics of Thymidine and Zidovudine in a Human Intestinal Epithelial Model System
-
Hu, M. Comparison of Uptake Characteristics of Thymidine and Zidovudine in a Human Intestinal Epithelial Model System. J. Pharm. Sci. 1993, 82, 829-833.
-
(1993)
J. Pharm. Sci.
, vol.82
, pp. 829-833
-
-
Hu, M.1
-
17
-
-
0029797173
-
Hypoxanthine enters human vascular endothelial cells (ECV 304) via the nitrobenzylthioinosine-insensitive equilibrative nucleoside transporter
-
Osses, N.; Pearson, J. D.; Yudilevich, D. L.; Javis, S. M. Hypoxanthine enters human vascular endothelial cells (ECV 304) via the nitrobenzylthioinosine-insensitive equilibrative nucleoside transporter. Biochem. J. 1996, 843-848.
-
(1996)
Biochem. J.
, pp. 843-848
-
-
Osses, N.1
Pearson, J.D.2
Yudilevich, D.L.3
Javis, S.M.4
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