Autocrine insulin action activates Akt and increases survival of isolated human islets

Diabetologia

Volumn 49, Issue 12, 2006, Pages 2900-2909

  Aikin, R ^a   Hanley, S ^a   Maysinger, D ^a   Lipsett, M ^a   Castellarin, M ^a   Paraskevas, S ^a   Rosenberg, L ^a,b  

^a MCGILL UNIVERSITY   (Canada)

^b MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

Akt; Apoptosis; Diabetes mellitus; Insulin; Islet transplantation; Islets of Langerhans

Indexed keywords

INSULIN; INSULIN ANTIBODY; INSULIN RECEPTOR ANTIBODY; INSULIN RECEPTOR KINASE; PROTEIN KINASE B;

ARTICLE; AUTOCRINE EFFECT; CELL CULTURE; CELL DEATH; CELL ISOLATION; CELL SURVIVAL; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN SYNTHESIS; PANCREAS ISLET; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION;

CADAVER; CELL SURVIVAL; CELLS, CULTURED; CULTURE MEDIA, CONDITIONED; ENZYME ACTIVATION; HUMANS; INSULIN; ISLETS OF LANGERHANS; KINETICS; MIDDLE AGED; MITOCHONDRIA; ORGAN SIZE; PANCREAS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 33750901819     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-006-0476-0     Document Type: Article

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