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Volumn 138, Issue 4, 1997, Pages 1427-1433

Specific inhibition of insulin-like growth factor-1 and insulin receptor tyrosine kinase activity and biological function by tyrphostins

Author keywords

[No Author keywords available]

Indexed keywords

3 BROMO 5 TERT BUTYL 4 HYDROXYBENZYLIDENEMALONONITRILE; 5 (2 BENZOTHIAZOLYL)THIOMETHYL 4 HYDROXY 3 METHOXYBENZYLIDENECYANOACETAMIDE; AG 1034; AG 1049; AG 1500; AG 1557; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TYRPHOSTIN; UNCLASSIFIED DRUG;

EID: 0030909657     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.4.5092     Document Type: Article
Times cited : (195)

References (29)
  • 3
    • 0028352022 scopus 로고
    • How does the mitogenic insulin-like growth factor-1 receptor differ from the metabolic insulin receptor?
    • LeRoith D, Sampson PC, Roberts Jr CT 1994 How does the mitogenic insulin-like growth factor-1 receptor differ from the metabolic insulin receptor? Horm Res 41 [Suppl 2]:74-79
    • (1994) Horm Res , vol.41 , Issue.2 SUPPL. , pp. 74-79
    • LeRoith, D.1    Sampson, P.C.2    Roberts Jr., C.T.3
  • 4
    • 0028863148 scopus 로고
    • The role of the tyrosine kinase domain of the insulin-like growth factor-1 receptor in intracellular signaling, cellular proliferation, and tumorigenesis
    • Hernández-Sáncher C, Blakesley VA, Kalebic T, Helman L, LeRoith D 1995 The role of the tyrosine kinase domain of the insulin-like growth factor-1 receptor in intracellular signaling, cellular proliferation, and tumorigenesis. J Biol Chem 270:29176-29181
    • (1995) J Biol Chem , Issue.270 , pp. 29176-29181
    • Hernández-Sáncher, C.1    Blakesley, V.A.2    Kalebic, T.3    Helman, L.4    LeRoith, D.5
  • 5
    • 0029119731 scopus 로고
    • Insulin-like growth factor-1 receptor. its role in cell proliferation, apoptosis and tumorigenicity
    • Resnicoff M, Burgaud JL, Rotman D, Abraham D, Baserga R 1995 Insulin-like growth factor-1 receptor. its role in cell proliferation, apoptosis and tumorigenicity. Lab Invest 73:311-331
    • (1995) Lab Invest , vol.73 , pp. 311-331
    • Resnicoff, M.1    Burgaud, J.L.2    Rotman, D.3    Abraham, D.4    Baserga, R.5
  • 6
    • 0026683954 scopus 로고
    • Insulin-like growth factor-1 inhibits apoptosis in interleukin-3-dependent hemopoietic cells
    • Rodríguez-Tarduchy G, Collins MKL, Garcia I, López-Rivas A 1992 Insulin-like growth factor-1 inhibits apoptosis in interleukin-3-dependent hemopoietic cells. J Immunol 149:535-540
    • (1992) J Immunol , vol.149 , pp. 535-540
    • Rodríguez-Tarduchy, G.1    Collins, M.K.L.2    Garcia, I.3    López-Rivas, A.4
  • 7
    • 0031014651 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 inhibits apoptosis using the phosphatidyl-inositol 3′ kinase pathway and the MAP kinase pathway
    • Párrizas M, Saltiel AR, LeRoith D 1997 Insulin-like growth factor-1 inhibits apoptosis using the phosphatidyl-inositol 3′ kinase pathway and the MAP kinase pathway. J Biol Chem 272:154-161
    • (1997) J Biol Chem , vol.272 , pp. 154-161
    • Párrizas, M.1    Saltiel, A.R.2    LeRoith, D.3
  • 8
    • 0025900420 scopus 로고
    • The pathway mediating insulin's effects on pyruvate dehydrogenase bypasses the insulin receptor tyrosine kinase
    • Gottschalk WK 1991 The pathway mediating insulin's effects on pyruvate dehydrogenase bypasses the insulin receptor tyrosine kinase. J Biol Chem 266:8814-8819
    • (1991) J Biol Chem , vol.266 , pp. 8814-8819
    • Gottschalk, W.K.1
  • 10
    • 0027402935 scopus 로고
    • Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-1 (IGF-1) receptor
    • Kato H, Faria TN, Stannard B, Roberts Jr CT, LeRoith D 1993 Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-1 (IGF-1) receptor. J Biol Chem 268:2655-2661
    • (1993) J Biol Chem , vol.268 , pp. 2655-2661
    • Kato, H.1    Faria, T.N.2    Stannard, B.3    Roberts Jr., C.T.4    LeRoith, D.5
  • 11
    • 0028893184 scopus 로고
    • Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-1 receptor abolishes autophosphorylation but does not eliminate biologic function
    • Blakesley VA, Kato H, Roberts Jr CT, LeRoith D 1995 Mutation of a conserved amino acid residue (tryptophan 1173) in the tyrosine kinase domain of the IGF-1 receptor abolishes autophosphorylation but does not eliminate biologic function. J Biol Chem 270:2764-2769
    • (1995) J Biol Chem , vol.270 , pp. 2764-2769
    • Blakesley, V.A.1    Kato, H.2    Roberts Jr., C.T.3    LeRoith, D.4
  • 12
    • 0023145547 scopus 로고
    • The molecular genetics of cancer
    • Bishop JM 1987 The molecular genetics of cancer. Science 235:305-311
    • (1987) Science , vol.235 , pp. 305-311
    • Bishop, J.M.1
  • 13
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Levitzki A, Gazit A 1995 Tyrosine kinase inhibition: an approach to drug development. Science 267:1782-1788
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 14
    • 0027198702 scopus 로고
    • Selective inhibition of the epidermal growth factor and HER2/Neu receptors by tyrphostins
    • Osherov N, Gazit A, Gilon C, Levitzki A 1993 Selective inhibition of the epidermal growth factor and HER2/Neu receptors by tyrphostins. J Biol Chem 268:11134-11142
    • (1993) J Biol Chem , vol.268 , pp. 11134-11142
    • Osherov, N.1    Gazit, A.2    Gilon, C.3    Levitzki, A.4
  • 15
    • 0027209064 scopus 로고
    • The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor
    • Ohmichi M, Pang L, Ribon V, Gazit A, Levitzki A, Saltiel AR 1993 The tyrosine kinase inhibitor tyrphostin blocks the cellular actions of nerve growth factor. Biochemistry 32:4650-4658
    • (1993) Biochemistry , vol.32 , pp. 4650-4658
    • Ohmichi, M.1    Pang, L.2    Ribon, V.3    Gazit, A.4    Levitzki, A.5    Saltiel, A.R.6
  • 17
    • 0028308567 scopus 로고
    • Two mutations in a conserved structural motif in the insulin receptor inhibit normal folding and intracellular transport of the receptor
    • Wertheimer E, Barbetti F, Muggeo M, Roth J, Taylor SI 1994 Two mutations in a conserved structural motif in the insulin receptor inhibit normal folding and intracellular transport of the receptor. J Biol Chem 269:7587-7592
    • (1994) J Biol Chem , vol.269 , pp. 7587-7592
    • Wertheimer, E.1    Barbetti, F.2    Muggeo, M.3    Roth, J.4    Taylor, S.I.5
  • 19
    • 0027241856 scopus 로고
    • The pathogenesis of atherosclerosis: A perspective for the 1990s
    • Ross R 1993 The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature 362:801-809
    • (1993) Nature , vol.362 , pp. 801-809
    • Ross, R.1
  • 20
    • 0027278677 scopus 로고
    • Increased expression of the insulin-like growth factor-1 receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product
    • Werner H, Re GG, Drummond IA, Sukhatme VP, Rauscher FJ, Sens DA, Garvin AJ, LeRoith D, Roberts Jr CT 1993 Increased expression of the insulin-like growth factor-1 receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product. Proc Natl Acad Sci USA 90:5828-5832
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 5828-5832
    • Werner, H.1    Re, G.G.2    Drummond, I.A.3    Sukhatme, V.P.4    Rauscher, F.J.5    Sens, D.A.6    Garvin, A.J.7    LeRoith, D.8    Roberts Jr., C.T.9
  • 21
    • 0028263811 scopus 로고
    • C-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington EA, Bennett MR, Fanidi A, Evan GI 1994 C-myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J 13:3286-3295
    • (1994) EMBO J , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 22
    • 0027483920 scopus 로고
    • Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibition of death by insulin-like growth factor 1 and cAMP
    • D'Mello SR, Galli C, Ciotti T, Calissano P 1993 Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor 1 and cAMP. Proc Natl Acad Sci USA 90:10989-10993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10989-10993
    • D'Mello, S.R.1    Galli, C.2    Ciotti, T.3    Calissano, P.4
  • 23
    • 0024240990 scopus 로고
    • Blocking of EGF- Dependent cell proliferation by EGF receptor kinase inhibitors
    • Yaish P, Gazit A, Gilon C, Levitzki A 1988 Blocking of EGF- dependent cell proliferation by EGF receptor kinase inhibitors. Science 242:933-935
    • (1988) Science , vol.242 , pp. 933-935
    • Yaish, P.1    Gazit, A.2    Gilon, C.3    Levitzki, A.4
  • 25
    • 0028171075 scopus 로고
    • Epidermal-growth-factor-dependent activation of the src-family kinases
    • Osherov N, Levitzki A 1994 Epidermal-growth-factor-dependent activation of the src-family kinases. Eur J Biochem 225:1047-1053
    • (1994) Eur J Biochem , vol.225 , pp. 1047-1053
    • Osherov, N.1    Levitzki, A.2
  • 27
    • 0026075305 scopus 로고
    • Use and specificity of genistein as inhibitor of protein-tyrosine kinases
    • Akiyama T, Ogawara H 1991 Use and specificity of genistein as inhibitor of protein-tyrosine kinases. Methods Enzymol 201:362-370
    • (1991) Methods Enzymol , vol.201 , pp. 362-370
    • Akiyama, T.1    Ogawara, H.2
  • 28
    • 0026047320 scopus 로고
    • Use of erbstatin as protein-tyrosine kinase inhibitor
    • Umezawa K, Imoto M 1991 Use of erbstatin as protein-tyrosine kinase inhibitor. Methods Enzymol 201:379-385
    • (1991) Methods Enzymol , vol.201 , pp. 379-385
    • Umezawa, K.1    Imoto, M.2
  • 29
    • 0028223221 scopus 로고
    • Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program
    • Posner I, Engel M, Gazit A, Levitzki A 1994 Kinetics of inhibition by tyrphostins of the tyrosine kinase activity of the epidermal growth factor receptor and analysis by a new computer program. Mol Pharmacol 45:673-683
    • (1994) Mol Pharmacol , vol.45 , pp. 673-683
    • Posner, I.1    Engel, M.2    Gazit, A.3    Levitzki, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.