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Volumn 108, Issue 3, 2006, Pages 385-394

Effect of aged garlic extract on APP processing and tau phosphorylation in Alzheimer's transgenic model Tg2576

Author keywords

Alzheimer's disease; Amyloid plaques; Cdk5; Di allyl disulfide; Garlic; GSK 3 ; S Allyl cysteine; Tau

Indexed keywords

AMYLOID; ANTIINFLAMMATORY AGENT; CHOLESTEROL; DIALLYL DISULFIDE; GARLIC EXTRACT; S ALLYLCYSTEINE;

EID: 33750606278     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2006.05.030     Document Type: Article
Times cited : (113)

References (60)
  • 1
    • 33750631192 scopus 로고    scopus 로고
    • Alzheimer's Data Base, Nidus Information Services, 2002. FDA Approved Clinical Drug Trials in Alzheimer's Treatment.
  • 2
    • 0036810329 scopus 로고    scopus 로고
    • Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies
    • Auld D.S., Kornecook T.J., Bastianetto S., and Quirion R. Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. Progresses in Neurobiology 68 (2002) 209-245
    • (2002) Progresses in Neurobiology , vol.68 , pp. 209-245
    • Auld, D.S.1    Kornecook, T.J.2    Bastianetto, S.3    Quirion, R.4
  • 3
    • 0037705997 scopus 로고    scopus 로고
    • Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory?
    • Balschun D., Wolfer D.P., Gass P., Mantamadiotis T., Welzl H., Schutz G., Frey J.U., and Lipp H.P. Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory?. Journal of Neuroscience 23 (2003) 6304-6314
    • (2003) Journal of Neuroscience , vol.23 , pp. 6304-6314
    • Balschun, D.1    Wolfer, D.P.2    Gass, P.3    Mantamadiotis, T.4    Welzl, H.5    Schutz, G.6    Frey, J.U.7    Lipp, H.P.8
  • 4
    • 0344825120 scopus 로고    scopus 로고
    • Molecular regulation of CD40 gene expression in macrophages and microglia
    • Benveniste E.N., Nguyen V.T., and Wesemann D.R. Molecular regulation of CD40 gene expression in macrophages and microglia. Brain Behavior Immunnology 18 (2004) 7-12
    • (2004) Brain Behavior Immunnology , vol.18 , pp. 7-12
    • Benveniste, E.N.1    Nguyen, V.T.2    Wesemann, D.R.3
  • 5
    • 0037276195 scopus 로고    scopus 로고
    • Anti-amyloidogenic effect of Allium sativum in Alzheimer's transgenic model Tg2576
    • Chauhan N.B. Anti-amyloidogenic effect of Allium sativum in Alzheimer's transgenic model Tg2576. Journal of Herbal Pharmacotherapy 3 (2003) 95-107
    • (2003) Journal of Herbal Pharmacotherapy , vol.3 , pp. 95-107
    • Chauhan, N.B.1
  • 6
    • 29144508430 scopus 로고    scopus 로고
    • Multiplicity of garlic health effects and Alzheimer's disease
    • Chauhan N.B. Multiplicity of garlic health effects and Alzheimer's disease. Journal of Nutrition Health & Aging 9 (2005) 412-432
    • (2005) Journal of Nutrition Health & Aging , vol.9 , pp. 412-432
    • Chauhan, N.B.1
  • 7
    • 0036644989 scopus 로고    scopus 로고
    • Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
    • Chauhan N.B., and Siegel G.J. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. Journal of Neuroscience Research 69 (2002) 10-23
    • (2002) Journal of Neuroscience Research , vol.69 , pp. 10-23
    • Chauhan, N.B.1    Siegel, G.J.2
  • 8
    • 0037411794 scopus 로고    scopus 로고
    • Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain
    • Chauhan N.B., and Siegel G.J. Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain. Neurochemistry International 43 (2003) 225-233
    • (2003) Neurochemistry International , vol.43 , pp. 225-233
    • Chauhan, N.B.1    Siegel, G.J.2
  • 9
    • 0141758165 scopus 로고    scopus 로고
    • Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576
    • Chauhan N.B., and Siegel G.J. Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576. Journal of Neuroscience Research 74 (2003) 142-147
    • (2003) Journal of Neuroscience Research , vol.74 , pp. 142-147
    • Chauhan, N.B.1    Siegel, G.J.2
  • 10
    • 9644272528 scopus 로고    scopus 로고
    • Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease
    • Chauhan N.B., and Siegel G.J. Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease. Expert Review on Vaccines 3 (2004) 717-725
    • (2004) Expert Review on Vaccines , vol.3 , pp. 717-725
    • Chauhan, N.B.1    Siegel, G.J.2
  • 11
    • 13444283725 scopus 로고    scopus 로고
    • Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8
    • Chauhan N.B., and Siegel G.J. Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8. Neuroscience Letters 375 (2005) 143-147
    • (2005) Neuroscience Letters , vol.375 , pp. 143-147
    • Chauhan, N.B.1    Siegel, G.J.2
  • 12
    • 0034959811 scopus 로고    scopus 로고
    • Depletion of glial cell line-derived neurotrophic factor in Substantia nigra neurons of Parkinson's disease brain
    • Chauhan N.B., Siegel G.J., and Lee J.M. Depletion of glial cell line-derived neurotrophic factor in Substantia nigra neurons of Parkinson's disease brain. Journal of Chemical Neuroanatomy 21 (2001) 277-288
    • (2001) Journal of Chemical Neuroanatomy , vol.21 , pp. 277-288
    • Chauhan, N.B.1    Siegel, G.J.2    Lee, J.M.3
  • 13
    • 0142102406 scopus 로고    scopus 로고
    • Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus.
    • Chauhan N.B., Lichtor T., and Siegel G.J. Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus. Brain Research 982 (2003) 219-227
    • (2003) Brain Research , vol.982 , pp. 219-227
    • Chauhan, N.B.1    Lichtor, T.2    Siegel, G.J.3
  • 14
    • 4644308807 scopus 로고    scopus 로고
    • Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain
    • Chauhan N.B., Siegel G.J., and Feinstein D.L. Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. Neurochemical Research 29 (2004) 1897-1911
    • (2004) Neurochemical Research , vol.29 , pp. 1897-1911
    • Chauhan, N.B.1    Siegel, G.J.2    Feinstein, D.L.3
  • 15
    • 9644305699 scopus 로고    scopus 로고
    • Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice
    • Chauhan N.B., Siegel G.J., and Lichtor T. Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice. Journal of Neuroscience Research 78 (2004) 732-741
    • (2004) Journal of Neuroscience Research , vol.78 , pp. 732-741
    • Chauhan, N.B.1    Siegel, G.J.2    Lichtor, T.3
  • 16
    • 11144284662 scopus 로고    scopus 로고
    • Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576
    • Chauhan N.B., Siegel G.J., and Feinstein D.L. Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576. Neuropharmacology 48 (2005) 93-104
    • (2005) Neuropharmacology , vol.48 , pp. 93-104
    • Chauhan, N.B.1    Siegel, G.J.2    Feinstein, D.L.3
  • 17
    • 0037151046 scopus 로고    scopus 로고
    • Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins
    • Dineley K.T., Xia X., Bui D., Sweatt J.D., and Zheng H. Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. Journal of Biological Chemistry 277 (2002) 22768-22780
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 22768-22780
    • Dineley, K.T.1    Xia, X.2    Bui, D.3    Sweatt, J.D.4    Zheng, H.5
  • 18
    • 0035282656 scopus 로고    scopus 로고
    • Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?
    • Dirsch V.M., and Vollmar A.M. Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?. Biochemical Pharmacology 61 (2001) 587-593
    • (2001) Biochemical Pharmacology , vol.61 , pp. 587-593
    • Dirsch, V.M.1    Vollmar, A.M.2
  • 19
    • 25844458239 scopus 로고    scopus 로고
    • Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies
    • Ferrer I., Gomez-Isla T., Puig B., Freixes M., Ribe E., Dalfo E., and Avila J. Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies. Current Alzheimer's Research 2 (2005) 3-18
    • (2005) Current Alzheimer's Research , vol.2 , pp. 3-18
    • Ferrer, I.1    Gomez-Isla, T.2    Puig, B.3    Freixes, M.4    Ribe, E.5    Dalfo, E.6    Avila, J.7
  • 20
    • 0025851252 scopus 로고
    • Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes
    • Gebhardt R. Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes. Arzneimittelforschung 41 (1991) 800-804
    • (1991) Arzneimittelforschung , vol.41 , pp. 800-804
    • Gebhardt, R.1
  • 21
    • 0028334763 scopus 로고
    • Inhibition of cholesterol biosynthesis by Allixin and Ajoene in rat hepatocytes and HepG2 cells
    • Gebhardt R., Beck H., and Wagner K.G. Inhibition of cholesterol biosynthesis by Allixin and Ajoene in rat hepatocytes and HepG2 cells. Biochimica et Biophysics Acta 1213 (1994) 57-62
    • (1994) Biochimica et Biophysics Acta , vol.1213 , pp. 57-62
    • Gebhardt, R.1    Beck, H.2    Wagner, K.G.3
  • 22
    • 0030473450 scopus 로고    scopus 로고
    • Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures
    • Gebhardt R., and Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. Lipids 31 (1996) 1269-1276
    • (1996) Lipids , vol.31 , pp. 1269-1276
    • Gebhardt, R.1    Beck, H.2
  • 23
    • 0030924820 scopus 로고    scopus 로고
    • S-Allyl-cysteine inhibits activation of nuclear factor kappa B in human T cells
    • Geng Z., Rong Y., and Lau B.H. S-Allyl-cysteine inhibits activation of nuclear factor kappa B in human T cells. Free Radical Biololgy & Medicine 23 (1997) 345-350
    • (1997) Free Radical Biololgy & Medicine , vol.23 , pp. 345-350
    • Geng, Z.1    Rong, Y.2    Lau, B.H.3
  • 24
    • 0038322504 scopus 로고    scopus 로고
    • Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis
    • Greenwood J., Walters C.E., Pryce G., Kanuga N., Beraud E., Baker D., and Adamson P. Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. FASEB Journal 17 (2003) 905-907
    • (2003) FASEB Journal , vol.17 , pp. 905-907
    • Greenwood, J.1    Walters, C.E.2    Pryce, G.3    Kanuga, N.4    Beraud, E.5    Baker, D.6    Adamson, P.7
  • 25
    • 15944371915 scopus 로고    scopus 로고
    • Cholesterol and Alzheimer's disease: statins, cholesterol depletion in APP processing and Abeta generation
    • Hartman T. Cholesterol and Alzheimer's disease: statins, cholesterol depletion in APP processing and Abeta generation. Subcellular Biochemistry 38 (2005) 365-380
    • (2005) Subcellular Biochemistry , vol.38 , pp. 365-380
    • Hartman, T.1
  • 27
    • 0002840537 scopus 로고
    • Biology and diseases of mice
    • Fx J.G., Cohen B.J., and Loew F.M. (Eds), Academic Press, Inc., San Diego
    • Jacoby R.O., and Fox J.E. Biology and diseases of mice. In: Fx J.G., Cohen B.J., and Loew F.M. (Eds). Laboratory Animal Medicine (1984), Academic Press, Inc., San Diego 84-109
    • (1984) Laboratory Animal Medicine , pp. 84-109
    • Jacoby, R.O.1    Fox, J.E.2
  • 28
    • 11144356498 scopus 로고    scopus 로고
    • Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease
    • Kawarabayashi T., Shoji M., Younkin L.H., Wen-Lang L., Dickson D.W., Murakami T., Matsubara E., Abe K., Ashe K.H., and Younkin S.G. Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease. Journal of Neuroscience 24 (2004) 3801-3809
    • (2004) Journal of Neuroscience , vol.24 , pp. 3801-3809
    • Kawarabayashi, T.1    Shoji, M.2    Younkin, L.H.3    Wen-Lang, L.4    Dickson, D.W.5    Murakami, T.6    Matsubara, E.7    Abe, K.8    Ashe, K.H.9    Younkin, S.G.10
  • 29
    • 0038267465 scopus 로고    scopus 로고
    • Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity
    • Keiss H.P., Dirsch V.M., Hartung T., Haffner T., Trueman L., Auger J., Kahane R., and Vollmar A.M. Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity. Journal of Nutrition 133 (2003) 2171-2175
    • (2003) Journal of Nutrition , vol.133 , pp. 2171-2175
    • Keiss, H.P.1    Dirsch, V.M.2    Hartung, T.3    Haffner, T.4    Trueman, L.5    Auger, J.6    Kahane, R.7    Vollmar, A.M.8
  • 31
    • 14844321855 scopus 로고    scopus 로고
    • Cholesterol homeostasis failure as a unifying cause of synaptic degeneration
    • Koudinov A.R., and Koudinova N.V. Cholesterol homeostasis failure as a unifying cause of synaptic degeneration. Journal of Neurological Sciences 229/230 (2005) 233-240
    • (2005) Journal of Neurological Sciences , vol.229-230 , pp. 233-240
    • Koudinov, A.R.1    Koudinova, N.V.2
  • 32
    • 23844509485 scopus 로고    scopus 로고
    • Composition, stability, and bioavailability of garlic products used in a clinical trial
    • Lawson L.D., and Gardner C.D. Composition, stability, and bioavailability of garlic products used in a clinical trial. Journal of Agriculture Food & Chemistry 53 (2005) 6254-6261
    • (2005) Journal of Agriculture Food & Chemistry , vol.53 , pp. 6254-6261
    • Lawson, L.D.1    Gardner, C.D.2
  • 33
    • 0034029294 scopus 로고    scopus 로고
    • Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic
    • Liu L., and Yeh Y.Y. Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic. Lipids 35 (2000) 197-203
    • (2000) Lipids , vol.35 , pp. 197-203
    • Liu, L.1    Yeh, Y.Y.2
  • 34
    • 0036270621 scopus 로고    scopus 로고
    • S-Alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes
    • Liu L., and Yeh Y.Y. S-Alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes. Journal of Nutrition 132 (2002) 1129-1134
    • (2002) Journal of Nutrition , vol.132 , pp. 1129-1134
    • Liu, L.1    Yeh, Y.Y.2
  • 36
    • 0034829801 scopus 로고    scopus 로고
    • The molecular bases of Alzheimer's disease and other neurodegenerative disorders
    • Maccioni R.B., Munoz J.P., and Barbeito L. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Archieves of Medical Research 32 (2001) 367-381
    • (2001) Archieves of Medical Research , vol.32 , pp. 367-381
    • Maccioni, R.B.1    Munoz, J.P.2    Barbeito, L.3
  • 37
    • 2542511697 scopus 로고    scopus 로고
    • Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum
    • Mesulam M., Shaw P., Mash D., and Weintraub S. Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum. Annals of Neurology 55 (2004) 815-828
    • (2004) Annals of Neurology , vol.55 , pp. 815-828
    • Mesulam, M.1    Shaw, P.2    Mash, D.3    Weintraub, S.4
  • 38
    • 0028596022 scopus 로고
    • Prolongation of life span and improved learning in the senescence accelerated mouse produced by aged garlic extract
    • Moriguchi T., Takashina K., Chu P.J., Saito H., and Nishiyama N. Prolongation of life span and improved learning in the senescence accelerated mouse produced by aged garlic extract. Biological Pharmacology Bulletin 17 (1994) 1589-1594
    • (1994) Biological Pharmacology Bulletin , vol.17 , pp. 1589-1594
    • Moriguchi, T.1    Takashina, K.2    Chu, P.J.3    Saito, H.4    Nishiyama, N.5
  • 39
    • 0029932180 scopus 로고    scopus 로고
    • Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse
    • Moriguchi T., Saito H., and Nishiyama N. Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse. Biological Pharmacology Bulletin 19 (1996) 305-307
    • (1996) Biological Pharmacology Bulletin , vol.19 , pp. 305-307
    • Moriguchi, T.1    Saito, H.2    Nishiyama, N.3
  • 41
    • 0035126248 scopus 로고    scopus 로고
    • Ameliorative effect of S-allylcysteine, a major thioallyl constituent in aged garlic extract, on learning deficits in senescence-accelerated mice
    • Nishiyama N., Moriguchi T., Morihara N., and Saito H. Ameliorative effect of S-allylcysteine, a major thioallyl constituent in aged garlic extract, on learning deficits in senescence-accelerated mice. Journal of Nutrition 131 (2001) 1093S-1095S
    • (2001) Journal of Nutrition , vol.131
    • Nishiyama, N.1    Moriguchi, T.2    Morihara, N.3    Saito, H.4
  • 42
    • 0035123594 scopus 로고    scopus 로고
    • S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia
    • Numagami Y., and Ohnishi S.T. S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia. Journal of Nutrition 131 (2001) 1100S-1105S
    • (2001) Journal of Nutrition , vol.131
    • Numagami, Y.1    Ohnishi, S.T.2
  • 45
    • 4143063543 scopus 로고    scopus 로고
    • Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding
    • Parvathy S., Ehrlich M., Pedrini S., Diaz N., Refolo L., Buxbaum J.D., Bogush A., Petanceska S., and Gandy S. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding. Journal of Neurochemistry 90 (2004) 1005-1010
    • (2004) Journal of Neurochemistry , vol.90 , pp. 1005-1010
    • Parvathy, S.1    Ehrlich, M.2    Pedrini, S.3    Diaz, N.4    Refolo, L.5    Buxbaum, J.D.6    Bogush, A.7    Petanceska, S.8    Gandy, S.9
  • 50
    • 0036257570 scopus 로고    scopus 로고
    • Garlic attenuates nitric oxide production in rat cardiac myocytes through inhibition of inducible nitric oxide synthase and the arginine transporter CAT-2 (cationic amino acid transporter-2)
    • Schwartz I.F., Hershkovitz R., Iaina A., Gnessin E., Wollman Y., Chernichowski T., Blum M., Levo Y., and Schwartz D. Garlic attenuates nitric oxide production in rat cardiac myocytes through inhibition of inducible nitric oxide synthase and the arginine transporter CAT-2 (cationic amino acid transporter-2). Clinical Sciences (London) 102 (2002) 487-493
    • (2002) Clinical Sciences (London) , vol.102 , pp. 487-493
    • Schwartz, I.F.1    Hershkovitz, R.2    Iaina, A.3    Gnessin, E.4    Wollman, Y.5    Chernichowski, T.6    Blum, M.7    Levo, Y.8    Schwartz, D.9
  • 51
    • 0034516988 scopus 로고    scopus 로고
    • Toward a comprehensive theory for Alzheimer's disease Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein
    • Selkoe D.J. Toward a comprehensive theory for Alzheimer's disease Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Annals of New York Academy of Sciences 924 (2000) 17-25
    • (2000) Annals of New York Academy of Sciences , vol.924 , pp. 17-25
    • Selkoe, D.J.1
  • 52
    • 33750612468 scopus 로고    scopus 로고
    • Linking amyloid and tau biology in Alzheimer's disease and its cholinergic aspects
    • Karczmar A.G. (Ed), Kluwer/Academic Press, New York
    • Siegel G.J., Chauhan N.B., and Karczmar A.G. Linking amyloid and tau biology in Alzheimer's disease and its cholinergic aspects. In: Karczmar A.G. (Ed). The Rise of Research on the Cholinergic Central Nervous System (2006), Kluwer/Academic Press, New York 569-627
    • (2006) The Rise of Research on the Cholinergic Central Nervous System , pp. 569-627
    • Siegel, G.J.1    Chauhan, N.B.2    Karczmar, A.G.3
  • 53
    • 18044398037 scopus 로고    scopus 로고
    • Alzheimer's disease: channeling APP to non-amyloidogenic processing
    • Tang B.L. Alzheimer's disease: channeling APP to non-amyloidogenic processing. Biochemistry Biophysics Research Communication 331 (2005) 375-378
    • (2005) Biochemistry Biophysics Research Communication , vol.331 , pp. 375-378
    • Tang, B.L.1
  • 57
    • 1842610852 scopus 로고    scopus 로고
    • Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
    • Wang Q., Walsh D.M., Rowan M.J., Selkoe D.J., and Anwyl R. Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5. Journal of Neuroscience 24 (2004) 3370-3378
    • (2004) Journal of Neuroscience , vol.24 , pp. 3370-3378
    • Wang, Q.1    Walsh, D.M.2    Rowan, M.J.3    Selkoe, D.J.4    Anwyl, R.5
  • 58
    • 0035653530 scopus 로고    scopus 로고
    • Colon cancer chemoprevention with ginseng and other botanicals
    • Wargovich M.J. Colon cancer chemoprevention with ginseng and other botanicals. Journal of Korean Medical Sciences 16 (2001) S81-S86
    • (2001) Journal of Korean Medical Sciences , vol.16
    • Wargovich, M.J.1
  • 59
    • 22844451171 scopus 로고    scopus 로고
    • Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy
    • Yu W., Ko M., Yanagisawa K., and Michikawa M. Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy. Journal of Biological Chemistry 280 (2005) 27296-27302
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 27296-27302
    • Yu, W.1    Ko, M.2    Yanagisawa, K.3    Michikawa, M.4


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