-
1
-
-
33750631192
-
-
Alzheimer's Data Base, Nidus Information Services, 2002. FDA Approved Clinical Drug Trials in Alzheimer's Treatment.
-
-
-
-
2
-
-
0036810329
-
Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies
-
Auld D.S., Kornecook T.J., Bastianetto S., and Quirion R. Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. Progresses in Neurobiology 68 (2002) 209-245
-
(2002)
Progresses in Neurobiology
, vol.68
, pp. 209-245
-
-
Auld, D.S.1
Kornecook, T.J.2
Bastianetto, S.3
Quirion, R.4
-
3
-
-
0037705997
-
Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory?
-
Balschun D., Wolfer D.P., Gass P., Mantamadiotis T., Welzl H., Schutz G., Frey J.U., and Lipp H.P. Does cAMP response element-binding protein have a pivotal role in hippocampal synaptic plasticity and hippocampus-dependent memory?. Journal of Neuroscience 23 (2003) 6304-6314
-
(2003)
Journal of Neuroscience
, vol.23
, pp. 6304-6314
-
-
Balschun, D.1
Wolfer, D.P.2
Gass, P.3
Mantamadiotis, T.4
Welzl, H.5
Schutz, G.6
Frey, J.U.7
Lipp, H.P.8
-
5
-
-
0037276195
-
Anti-amyloidogenic effect of Allium sativum in Alzheimer's transgenic model Tg2576
-
Chauhan N.B. Anti-amyloidogenic effect of Allium sativum in Alzheimer's transgenic model Tg2576. Journal of Herbal Pharmacotherapy 3 (2003) 95-107
-
(2003)
Journal of Herbal Pharmacotherapy
, vol.3
, pp. 95-107
-
-
Chauhan, N.B.1
-
6
-
-
29144508430
-
Multiplicity of garlic health effects and Alzheimer's disease
-
Chauhan N.B. Multiplicity of garlic health effects and Alzheimer's disease. Journal of Nutrition Health & Aging 9 (2005) 412-432
-
(2005)
Journal of Nutrition Health & Aging
, vol.9
, pp. 412-432
-
-
Chauhan, N.B.1
-
7
-
-
0036644989
-
Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody
-
Chauhan N.B., and Siegel G.J. Reversal of amyloid beta toxicity in Alzheimer's disease model Tg2576 by intraventricular antiamyloid beta antibody. Journal of Neuroscience Research 69 (2002) 10-23
-
(2002)
Journal of Neuroscience Research
, vol.69
, pp. 10-23
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
8
-
-
0037411794
-
Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain
-
Chauhan N.B., and Siegel G.J. Effect of PPF and ALCAR on the induction of NGF- and p75-mRNA and on APP processing in Tg2576 brain. Neurochemistry International 43 (2003) 225-233
-
(2003)
Neurochemistry International
, vol.43
, pp. 225-233
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
9
-
-
0141758165
-
Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576
-
Chauhan N.B., and Siegel G.J. Intracerebroventricular passive immunization with anti-Abeta antibody in Tg2576. Journal of Neuroscience Research 74 (2003) 142-147
-
(2003)
Journal of Neuroscience Research
, vol.74
, pp. 142-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
10
-
-
9644272528
-
Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease
-
Chauhan N.B., and Siegel G.J. Intracerebroventricular passive immunization in transgenic mouse models of Alzheimer's disease. Expert Review on Vaccines 3 (2004) 717-725
-
(2004)
Expert Review on Vaccines
, vol.3
, pp. 717-725
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
11
-
-
13444283725
-
Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8
-
Chauhan N.B., and Siegel G.J. Efficacy of anti-Abeta antibody isotypes used for intracerebroventricular immunization in TgCRND8. Neuroscience Letters 375 (2005) 143-147
-
(2005)
Neuroscience Letters
, vol.375
, pp. 143-147
-
-
Chauhan, N.B.1
Siegel, G.J.2
-
12
-
-
0034959811
-
Depletion of glial cell line-derived neurotrophic factor in Substantia nigra neurons of Parkinson's disease brain
-
Chauhan N.B., Siegel G.J., and Lee J.M. Depletion of glial cell line-derived neurotrophic factor in Substantia nigra neurons of Parkinson's disease brain. Journal of Chemical Neuroanatomy 21 (2001) 277-288
-
(2001)
Journal of Chemical Neuroanatomy
, vol.21
, pp. 277-288
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lee, J.M.3
-
13
-
-
0142102406
-
Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus.
-
Chauhan N.B., Lichtor T., and Siegel G.J. Aging potentiates Abeta-induced depletion of SNAP-25 in mouse hippocampus. Brain Research 982 (2003) 219-227
-
(2003)
Brain Research
, vol.982
, pp. 219-227
-
-
Chauhan, N.B.1
Lichtor, T.2
Siegel, G.J.3
-
14
-
-
4644308807
-
Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain
-
Chauhan N.B., Siegel G.J., and Feinstein D.L. Effects of lovastatin and pravastatin on amyloid processing and inflammatory response in TgCRND8 brain. Neurochemical Research 29 (2004) 1897-1911
-
(2004)
Neurochemical Research
, vol.29
, pp. 1897-1911
-
-
Chauhan, N.B.1
Siegel, G.J.2
Feinstein, D.L.3
-
15
-
-
9644305699
-
Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice
-
Chauhan N.B., Siegel G.J., and Lichtor T. Effect of age on the duration and extent of amyloid plaque reduction and microglial activation after injection of anti-Abeta antibody into the third ventricle of TgCRND8 mice. Journal of Neuroscience Research 78 (2004) 732-741
-
(2004)
Journal of Neuroscience Research
, vol.78
, pp. 732-741
-
-
Chauhan, N.B.1
Siegel, G.J.2
Lichtor, T.3
-
16
-
-
11144284662
-
Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576
-
Chauhan N.B., Siegel G.J., and Feinstein D.L. Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576. Neuropharmacology 48 (2005) 93-104
-
(2005)
Neuropharmacology
, vol.48
, pp. 93-104
-
-
Chauhan, N.B.1
Siegel, G.J.2
Feinstein, D.L.3
-
17
-
-
0037151046
-
Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins
-
Dineley K.T., Xia X., Bui D., Sweatt J.D., and Zheng H. Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins. Journal of Biological Chemistry 277 (2002) 22768-22780
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 22768-22780
-
-
Dineley, K.T.1
Xia, X.2
Bui, D.3
Sweatt, J.D.4
Zheng, H.5
-
18
-
-
0035282656
-
Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?
-
Dirsch V.M., and Vollmar A.M. Ajoene, a natural product with non-steroidal anti-inflammatory drug (NSAID)-like properties?. Biochemical Pharmacology 61 (2001) 587-593
-
(2001)
Biochemical Pharmacology
, vol.61
, pp. 587-593
-
-
Dirsch, V.M.1
Vollmar, A.M.2
-
19
-
-
25844458239
-
Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies
-
Ferrer I., Gomez-Isla T., Puig B., Freixes M., Ribe E., Dalfo E., and Avila J. Current advances on different kinases involved in tau phosphorylation, and implications in Alzheimer's disease and tauopathies. Current Alzheimer's Research 2 (2005) 3-18
-
(2005)
Current Alzheimer's Research
, vol.2
, pp. 3-18
-
-
Ferrer, I.1
Gomez-Isla, T.2
Puig, B.3
Freixes, M.4
Ribe, E.5
Dalfo, E.6
Avila, J.7
-
20
-
-
0025851252
-
Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes
-
Gebhardt R. Inhibition of cholesterol biosynthesis by a water-soluble garlic extract in primary cultures of rat hepatocytes. Arzneimittelforschung 41 (1991) 800-804
-
(1991)
Arzneimittelforschung
, vol.41
, pp. 800-804
-
-
Gebhardt, R.1
-
21
-
-
0028334763
-
Inhibition of cholesterol biosynthesis by Allixin and Ajoene in rat hepatocytes and HepG2 cells
-
Gebhardt R., Beck H., and Wagner K.G. Inhibition of cholesterol biosynthesis by Allixin and Ajoene in rat hepatocytes and HepG2 cells. Biochimica et Biophysics Acta 1213 (1994) 57-62
-
(1994)
Biochimica et Biophysics Acta
, vol.1213
, pp. 57-62
-
-
Gebhardt, R.1
Beck, H.2
Wagner, K.G.3
-
22
-
-
0030473450
-
Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures
-
Gebhardt R., and Beck H. Differential inhibitory effects of garlic-derived organosulfur compounds on cholesterol biosynthesis in primary rat hepatocyte cultures. Lipids 31 (1996) 1269-1276
-
(1996)
Lipids
, vol.31
, pp. 1269-1276
-
-
Gebhardt, R.1
Beck, H.2
-
23
-
-
0030924820
-
S-Allyl-cysteine inhibits activation of nuclear factor kappa B in human T cells
-
Geng Z., Rong Y., and Lau B.H. S-Allyl-cysteine inhibits activation of nuclear factor kappa B in human T cells. Free Radical Biololgy & Medicine 23 (1997) 345-350
-
(1997)
Free Radical Biololgy & Medicine
, vol.23
, pp. 345-350
-
-
Geng, Z.1
Rong, Y.2
Lau, B.H.3
-
24
-
-
0038322504
-
Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis
-
Greenwood J., Walters C.E., Pryce G., Kanuga N., Beraud E., Baker D., and Adamson P. Lovastatin inhibits brain endothelial cell Rho-mediated lymphocyte migration and attenuates experimental autoimmune encephalomyelitis. FASEB Journal 17 (2003) 905-907
-
(2003)
FASEB Journal
, vol.17
, pp. 905-907
-
-
Greenwood, J.1
Walters, C.E.2
Pryce, G.3
Kanuga, N.4
Beraud, E.5
Baker, D.6
Adamson, P.7
-
25
-
-
15944371915
-
Cholesterol and Alzheimer's disease: statins, cholesterol depletion in APP processing and Abeta generation
-
Hartman T. Cholesterol and Alzheimer's disease: statins, cholesterol depletion in APP processing and Abeta generation. Subcellular Biochemistry 38 (2005) 365-380
-
(2005)
Subcellular Biochemistry
, vol.38
, pp. 365-380
-
-
Hartman, T.1
-
26
-
-
20844457621
-
The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease
-
Hoglund K., Thelen K.M., Syversen S., Sjogren M., von Bergmann K., Wallin A., Vanmechelen E., Vanderstichele H., Lutjohann D., and Blennow K. The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease. Dementia Geriatrics & Cognitive Disorders 19 (2005) 256-265
-
(2005)
Dementia Geriatrics & Cognitive Disorders
, vol.19
, pp. 256-265
-
-
Hoglund, K.1
Thelen, K.M.2
Syversen, S.3
Sjogren, M.4
von Bergmann, K.5
Wallin, A.6
Vanmechelen, E.7
Vanderstichele, H.8
Lutjohann, D.9
Blennow, K.10
-
27
-
-
0002840537
-
Biology and diseases of mice
-
Fx J.G., Cohen B.J., and Loew F.M. (Eds), Academic Press, Inc., San Diego
-
Jacoby R.O., and Fox J.E. Biology and diseases of mice. In: Fx J.G., Cohen B.J., and Loew F.M. (Eds). Laboratory Animal Medicine (1984), Academic Press, Inc., San Diego 84-109
-
(1984)
Laboratory Animal Medicine
, pp. 84-109
-
-
Jacoby, R.O.1
Fox, J.E.2
-
28
-
-
11144356498
-
Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease
-
Kawarabayashi T., Shoji M., Younkin L.H., Wen-Lang L., Dickson D.W., Murakami T., Matsubara E., Abe K., Ashe K.H., and Younkin S.G. Dimeric amyloid beta protein rapidly accumulates in lipid rafts followed by apolipoprotein E and phosphorylated tau accumulation in the Tg2576 mouse model of Alzheimer's disease. Journal of Neuroscience 24 (2004) 3801-3809
-
(2004)
Journal of Neuroscience
, vol.24
, pp. 3801-3809
-
-
Kawarabayashi, T.1
Shoji, M.2
Younkin, L.H.3
Wen-Lang, L.4
Dickson, D.W.5
Murakami, T.6
Matsubara, E.7
Abe, K.8
Ashe, K.H.9
Younkin, S.G.10
-
29
-
-
0038267465
-
Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity
-
Keiss H.P., Dirsch V.M., Hartung T., Haffner T., Trueman L., Auger J., Kahane R., and Vollmar A.M. Garlic (Allium sativum L.) modulates cytokine expression in lipopolysaccharide-activated human blood thereby inhibiting NF-kappaB activity. Journal of Nutrition 133 (2003) 2171-2175
-
(2003)
Journal of Nutrition
, vol.133
, pp. 2171-2175
-
-
Keiss, H.P.1
Dirsch, V.M.2
Hartung, T.3
Haffner, T.4
Trueman, L.5
Auger, J.6
Kahane, R.7
Vollmar, A.M.8
-
30
-
-
0035313202
-
Differential regulation of NO availability from macrophages and endothelial cells by the garlic component S-allylcysteine
-
Kim K.M., Chun S.B., Koo M.S., Choi W.J., Kim T.W., Kwon Y.G., Chung H.T., Billiar T.R., and Kim Y.M. Differential regulation of NO availability from macrophages and endothelial cells by the garlic component S-allylcysteine. Free Radical Biology Medicine 30 (2001) 747-756
-
(2001)
Free Radical Biology Medicine
, vol.30
, pp. 747-756
-
-
Kim, K.M.1
Chun, S.B.2
Koo, M.S.3
Choi, W.J.4
Kim, T.W.5
Kwon, Y.G.6
Chung, H.T.7
Billiar, T.R.8
Kim, Y.M.9
-
31
-
-
14844321855
-
Cholesterol homeostasis failure as a unifying cause of synaptic degeneration
-
Koudinov A.R., and Koudinova N.V. Cholesterol homeostasis failure as a unifying cause of synaptic degeneration. Journal of Neurological Sciences 229/230 (2005) 233-240
-
(2005)
Journal of Neurological Sciences
, vol.229-230
, pp. 233-240
-
-
Koudinov, A.R.1
Koudinova, N.V.2
-
32
-
-
23844509485
-
Composition, stability, and bioavailability of garlic products used in a clinical trial
-
Lawson L.D., and Gardner C.D. Composition, stability, and bioavailability of garlic products used in a clinical trial. Journal of Agriculture Food & Chemistry 53 (2005) 6254-6261
-
(2005)
Journal of Agriculture Food & Chemistry
, vol.53
, pp. 6254-6261
-
-
Lawson, L.D.1
Gardner, C.D.2
-
33
-
-
0034029294
-
Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic
-
Liu L., and Yeh Y.Y. Inhibition of cholesterol biosynthesis by organosulfur compounds derived from garlic. Lipids 35 (2000) 197-203
-
(2000)
Lipids
, vol.35
, pp. 197-203
-
-
Liu, L.1
Yeh, Y.Y.2
-
34
-
-
0036270621
-
S-Alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes
-
Liu L., and Yeh Y.Y. S-Alk(en)yl cysteines of garlic inhibit cholesterol synthesis by deactivating HMG-CoA reductase in cultured rat hepatocytes. Journal of Nutrition 132 (2002) 1129-1134
-
(2002)
Journal of Nutrition
, vol.132
, pp. 1129-1134
-
-
Liu, L.1
Yeh, Y.Y.2
-
35
-
-
9644257211
-
Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain
-
Liu S.J., Zhang J.Y., Li H.L., Fang Z.Y., Wang Q., Deng H.M., Gong C.X., Grundke-Iqbal I., Iqba K., and Wang J.Z. Tau becomes a more favorable substrate for GSK-3 when it is prephosphorylated by PKA in rat brain. Journal of Biological Chemistry 279 (2004) 50078-50088
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 50078-50088
-
-
Liu, S.J.1
Zhang, J.Y.2
Li, H.L.3
Fang, Z.Y.4
Wang, Q.5
Deng, H.M.6
Gong, C.X.7
Grundke-Iqbal, I.8
Iqba, K.9
Wang, J.Z.10
-
36
-
-
0034829801
-
The molecular bases of Alzheimer's disease and other neurodegenerative disorders
-
Maccioni R.B., Munoz J.P., and Barbeito L. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Archieves of Medical Research 32 (2001) 367-381
-
(2001)
Archieves of Medical Research
, vol.32
, pp. 367-381
-
-
Maccioni, R.B.1
Munoz, J.P.2
Barbeito, L.3
-
37
-
-
2542511697
-
Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum
-
Mesulam M., Shaw P., Mash D., and Weintraub S. Cholinergic nucleus basalis tauopathy emerges early in the aging-MCI-AD continuum. Annals of Neurology 55 (2004) 815-828
-
(2004)
Annals of Neurology
, vol.55
, pp. 815-828
-
-
Mesulam, M.1
Shaw, P.2
Mash, D.3
Weintraub, S.4
-
38
-
-
0028596022
-
Prolongation of life span and improved learning in the senescence accelerated mouse produced by aged garlic extract
-
Moriguchi T., Takashina K., Chu P.J., Saito H., and Nishiyama N. Prolongation of life span and improved learning in the senescence accelerated mouse produced by aged garlic extract. Biological Pharmacology Bulletin 17 (1994) 1589-1594
-
(1994)
Biological Pharmacology Bulletin
, vol.17
, pp. 1589-1594
-
-
Moriguchi, T.1
Takashina, K.2
Chu, P.J.3
Saito, H.4
Nishiyama, N.5
-
39
-
-
0029932180
-
Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse
-
Moriguchi T., Saito H., and Nishiyama N. Aged garlic extract prolongs longevity and improves spatial memory deficit in senescence-accelerated mouse. Biological Pharmacology Bulletin 19 (1996) 305-307
-
(1996)
Biological Pharmacology Bulletin
, vol.19
, pp. 305-307
-
-
Moriguchi, T.1
Saito, H.2
Nishiyama, N.3
-
40
-
-
1542614533
-
Regional analysis of differently phosphorylated tau proteins in brains from patients with Alzheimer's disease
-
Nakano H., Kobayashi K., Sugimori K., Shimazaki M., Miyazu K., Hayashi M., and Furuta H. Regional analysis of differently phosphorylated tau proteins in brains from patients with Alzheimer's disease. Dementia, Geriatrics & Cognitive Disorders 17 (2004) 122-131
-
(2004)
Dementia, Geriatrics & Cognitive Disorders
, vol.17
, pp. 122-131
-
-
Nakano, H.1
Kobayashi, K.2
Sugimori, K.3
Shimazaki, M.4
Miyazu, K.5
Hayashi, M.6
Furuta, H.7
-
41
-
-
0035126248
-
Ameliorative effect of S-allylcysteine, a major thioallyl constituent in aged garlic extract, on learning deficits in senescence-accelerated mice
-
Nishiyama N., Moriguchi T., Morihara N., and Saito H. Ameliorative effect of S-allylcysteine, a major thioallyl constituent in aged garlic extract, on learning deficits in senescence-accelerated mice. Journal of Nutrition 131 (2001) 1093S-1095S
-
(2001)
Journal of Nutrition
, vol.131
-
-
Nishiyama, N.1
Moriguchi, T.2
Morihara, N.3
Saito, H.4
-
42
-
-
0035123594
-
S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia
-
Numagami Y., and Ohnishi S.T. S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia. Journal of Nutrition 131 (2001) 1100S-1105S
-
(2001)
Journal of Nutrition
, vol.131
-
-
Numagami, Y.1
Ohnishi, S.T.2
-
43
-
-
0142045683
-
Cholesterol and tau protein-findings in Alzheimer's and Niemann Pick C's disease
-
Ohm T.G., Treiber-Held S., Distl R., Glockner F., Schonheit B., Tamanai M., and Meske V. Cholesterol and tau protein-findings in Alzheimer's and Niemann Pick C's disease. Pharmacopsychiatry 36 (2003) S120-S126
-
(2003)
Pharmacopsychiatry
, vol.36
-
-
Ohm, T.G.1
Treiber-Held, S.2
Distl, R.3
Glockner, F.4
Schonheit, B.5
Tamanai, M.6
Meske, V.7
-
44
-
-
0036771832
-
AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576
-
Otth C., Concha I.I., Arendt T., Stieler J., Schliebs R., Gonzalez-Billault C., and Maccioni R.B. AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576. Journal of Alzheimer's Disease 4 (2002) 417-430
-
(2002)
Journal of Alzheimer's Disease
, vol.4
, pp. 417-430
-
-
Otth, C.1
Concha, I.I.2
Arendt, T.3
Stieler, J.4
Schliebs, R.5
Gonzalez-Billault, C.6
Maccioni, R.B.7
-
45
-
-
4143063543
-
Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding
-
Parvathy S., Ehrlich M., Pedrini S., Diaz N., Refolo L., Buxbaum J.D., Bogush A., Petanceska S., and Gandy S. Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding. Journal of Neurochemistry 90 (2004) 1005-1010
-
(2004)
Journal of Neurochemistry
, vol.90
, pp. 1005-1010
-
-
Parvathy, S.1
Ehrlich, M.2
Pedrini, S.3
Diaz, N.4
Refolo, L.5
Buxbaum, J.D.6
Bogush, A.7
Petanceska, S.8
Gandy, S.9
-
46
-
-
15744397372
-
Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK
-
Pedrini S., Carter T.L., Prendergast G., Petanceska S., Ehrlich M.E., and Gandy S. Modulation of statin-activated shedding of Alzheimer APP ectodomain by ROCK. PLoS Medicine 2 (2005) e18
-
(2005)
PLoS Medicine
, vol.2
-
-
Pedrini, S.1
Carter, T.L.2
Prendergast, G.3
Petanceska, S.4
Ehrlich, M.E.5
Gandy, S.6
-
47
-
-
27744511921
-
High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice
-
Rahman A., Akterin S., Flores-Morales A., Crisby M., Kivipelto M., Schultzberg M., and Cedazo-Minguez A. High cholesterol diet induces tau hyperphosphorylation in apolipoprotein E deficient mice. FEBS Letters 579 (2005) 6411-6416
-
(2005)
FEBS Letters
, vol.579
, pp. 6411-6416
-
-
Rahman, A.1
Akterin, S.2
Flores-Morales, A.3
Crisby, M.4
Kivipelto, M.5
Schultzberg, M.6
Cedazo-Minguez, A.7
-
49
-
-
0344926464
-
Divergent roles of GSK3 and CDK5 in APP processing
-
Ryder J., Su Y., Liu F., Li B., Zhou Y., and Ni B. Divergent roles of GSK3 and CDK5 in APP processing. Biochemistry Biophysics Research Communication 312 (2003) 922-929
-
(2003)
Biochemistry Biophysics Research Communication
, vol.312
, pp. 922-929
-
-
Ryder, J.1
Su, Y.2
Liu, F.3
Li, B.4
Zhou, Y.5
Ni, B.6
-
50
-
-
0036257570
-
Garlic attenuates nitric oxide production in rat cardiac myocytes through inhibition of inducible nitric oxide synthase and the arginine transporter CAT-2 (cationic amino acid transporter-2)
-
Schwartz I.F., Hershkovitz R., Iaina A., Gnessin E., Wollman Y., Chernichowski T., Blum M., Levo Y., and Schwartz D. Garlic attenuates nitric oxide production in rat cardiac myocytes through inhibition of inducible nitric oxide synthase and the arginine transporter CAT-2 (cationic amino acid transporter-2). Clinical Sciences (London) 102 (2002) 487-493
-
(2002)
Clinical Sciences (London)
, vol.102
, pp. 487-493
-
-
Schwartz, I.F.1
Hershkovitz, R.2
Iaina, A.3
Gnessin, E.4
Wollman, Y.5
Chernichowski, T.6
Blum, M.7
Levo, Y.8
Schwartz, D.9
-
51
-
-
0034516988
-
Toward a comprehensive theory for Alzheimer's disease Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein
-
Selkoe D.J. Toward a comprehensive theory for Alzheimer's disease Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Annals of New York Academy of Sciences 924 (2000) 17-25
-
(2000)
Annals of New York Academy of Sciences
, vol.924
, pp. 17-25
-
-
Selkoe, D.J.1
-
52
-
-
33750612468
-
Linking amyloid and tau biology in Alzheimer's disease and its cholinergic aspects
-
Karczmar A.G. (Ed), Kluwer/Academic Press, New York
-
Siegel G.J., Chauhan N.B., and Karczmar A.G. Linking amyloid and tau biology in Alzheimer's disease and its cholinergic aspects. In: Karczmar A.G. (Ed). The Rise of Research on the Cholinergic Central Nervous System (2006), Kluwer/Academic Press, New York 569-627
-
(2006)
The Rise of Research on the Cholinergic Central Nervous System
, pp. 569-627
-
-
Siegel, G.J.1
Chauhan, N.B.2
Karczmar, A.G.3
-
53
-
-
18044398037
-
Alzheimer's disease: channeling APP to non-amyloidogenic processing
-
Tang B.L. Alzheimer's disease: channeling APP to non-amyloidogenic processing. Biochemistry Biophysics Research Communication 331 (2005) 375-378
-
(2005)
Biochemistry Biophysics Research Communication
, vol.331
, pp. 375-378
-
-
Tang, B.L.1
-
54
-
-
0035936683
-
Abeta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice
-
Tomidokoro Y., Ishiguro K., Harigaya Y., Matsubara E., Ikeda M., Park J.M., Yasutake K., Kawarabayashi T., Okamoto K., and Shoji M. Abeta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice. Neuroscience Letters 299 (2001) 169-172
-
(2001)
Neuroscience Letters
, vol.299
, pp. 169-172
-
-
Tomidokoro, Y.1
Ishiguro, K.2
Harigaya, Y.3
Matsubara, E.4
Ikeda, M.5
Park, J.M.6
Yasutake, K.7
Kawarabayashi, T.8
Okamoto, K.9
Shoji, M.10
-
55
-
-
4744340436
-
Lovastatin modulation of microglial activation via suppression of functional CD40 expression
-
Townsend K.P., Shytle D.R., Bai Y., San N., Zeng J., Freeman M., Mori T., Fernandez F., Morgan D., Sanberg P., and Tan J. Lovastatin modulation of microglial activation via suppression of functional CD40 expression. Journal of Neuroscience Research 78 (2004) 167-176
-
(2004)
Journal of Neuroscience Research
, vol.78
, pp. 167-176
-
-
Townsend, K.P.1
Shytle, D.R.2
Bai, Y.3
San, N.4
Zeng, J.5
Freeman, M.6
Mori, T.7
Fernandez, F.8
Morgan, D.9
Sanberg, P.10
Tan, J.11
-
56
-
-
0036792096
-
Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling
-
Vitolo O.V., Sant'Angelo A., Costanzo V., Battaglia F., Arancio O., and Shelanski M. Amyloid beta-peptide inhibition of the PKA/CREB pathway and long-term potentiation: reversibility by drugs that enhance cAMP signaling. Proceedings of National Academy of Sciences of the United States of America 99 (2002) 13217-13221
-
(2002)
Proceedings of National Academy of Sciences of the United States of America
, vol.99
, pp. 13217-13221
-
-
Vitolo, O.V.1
Sant'Angelo, A.2
Costanzo, V.3
Battaglia, F.4
Arancio, O.5
Shelanski, M.6
-
57
-
-
1842610852
-
Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5
-
Wang Q., Walsh D.M., Rowan M.J., Selkoe D.J., and Anwyl R. Block of long-term potentiation by naturally secreted and synthetic amyloid beta-peptide in hippocampal slices is mediated via activation of the kinases c-Jun N-terminal kinase, cyclin-dependent kinase 5, and p38 mitogen-activated protein kinase as well as metabotropic glutamate receptor type 5. Journal of Neuroscience 24 (2004) 3370-3378
-
(2004)
Journal of Neuroscience
, vol.24
, pp. 3370-3378
-
-
Wang, Q.1
Walsh, D.M.2
Rowan, M.J.3
Selkoe, D.J.4
Anwyl, R.5
-
58
-
-
0035653530
-
Colon cancer chemoprevention with ginseng and other botanicals
-
Wargovich M.J. Colon cancer chemoprevention with ginseng and other botanicals. Journal of Korean Medical Sciences 16 (2001) S81-S86
-
(2001)
Journal of Korean Medical Sciences
, vol.16
-
-
Wargovich, M.J.1
-
59
-
-
22844451171
-
Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy
-
Yu W., Ko M., Yanagisawa K., and Michikawa M. Neurodegeneration in heterozygous Niemann-Pick type C1 (NPC1) mouse: implication of heterozygous NPC1 mutations being a risk for tauopathy. Journal of Biological Chemistry 280 (2005) 27296-27302
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 27296-27302
-
-
Yu, W.1
Ko, M.2
Yanagisawa, K.3
Michikawa, M.4
-
60
-
-
13244264765
-
A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons
-
Zheng Y.L., Kesavapany S., Gravell M., Hamilton R.S., Schubert M., Amin N., Albers W., Grant P., and Pant H.C. A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons. EMBO Journal 24 (2005) 209-220
-
(2005)
EMBO Journal
, vol.24
, pp. 209-220
-
-
Zheng, Y.L.1
Kesavapany, S.2
Gravell, M.3
Hamilton, R.S.4
Schubert, M.5
Amin, N.6
Albers, W.7
Grant, P.8
Pant, H.C.9
|