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Volumn 17, Issue 3, 2004, Pages 122-131

Regional analysis of differently phosphorylated tau proteins in brains from patients with Alzheimer's disease

Author keywords

Alzheimer's disease; AT180; AT8; HT7; Neurofibrillary tangles; Tau protein; Tau2; Tau5

Indexed keywords

MONOCLONAL ANTIBODY; TAU PROTEIN;

EID: 1542614533     PISSN: 14208008     EISSN: None     Source Type: Journal    
DOI: 10.1159/000076344     Document Type: Article
Times cited : (19)

References (32)
  • 2
    • 0027939401 scopus 로고
    • Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites
    • Su JH, Cummings BJ, Cotman CW: Early phosphorylation of tau in Alzheimer's disease occurs at Ser-202 and is preferentially located within neurites. Neuroreport 1994;5:2358-2362.
    • (1994) Neuroreport , vol.5 , pp. 2358-2362
    • Su, J.H.1    Cummings, B.J.2    Cotman, C.W.3
  • 3
  • 5
    • 0025908356 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's disease (CERAD). 2. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L, and participating CERAD neuropathologists: The Consortium to Establish a Registry for Alzheimer's disease (CERAD). 2. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology 1991;41:479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Sumi, S.M.4    Crain, B.J.5    Brownlee, L.M.6    Vogel, F.S.7    Hughes, J.P.8    Van Belle, G.9    Berg, L.10
  • 6
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian ZS: Diagnosis of Alzheimer's disease. Arch Neurol 1985;42:1097-1105.
    • (1985) Arch Neurol , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 7
    • 0025863618 scopus 로고
    • Neuropathological staging of Alzheimer-related changes
    • Berl
    • Braak H, Braak E: Neuropathological staging of Alzheimer-related changes. Acta Neuropathol (Berl) 1991;82:239-259.
    • (1991) Acta Neuropathol , vol.82 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 8
    • 0036937699 scopus 로고    scopus 로고
    • Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
    • Berl
    • Augustinack JC, Schneider A, Mandelkow EM, Hyman BT: Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol (Berl) 2002;103:26-35.
    • (2002) Acta Neuropathol , vol.103 , pp. 26-35
    • Augustinack, J.C.1    Schneider, A.2    Mandelkow, E.M.3    Hyman, B.T.4
  • 9
    • 0024561445 scopus 로고
    • Tau protein immunoreactivity in dementia of the Alzheimer type. 1. Morphology, evolution, distribution, and pathogenetic implications
    • Papasozomenos SC: Tau protein immunoreactivity in dementia of the Alzheimer type. 1. Morphology, evolution, distribution, and pathogenetic implications. Lab Invest 1989;60:123-137.
    • (1989) Lab Invest , vol.60 , pp. 123-137
    • Papasozomenos, S.C.1
  • 10
    • 0025360661 scopus 로고
    • Correlation between microscopical changes and Tau 64 and 69 biochemical detection in senile dementia of the Alzheimer type. Tau 64 and 69 are reliable markers of the neurofibrillary degeneration
    • Berl
    • Flament S, Delacourte A, Delaere P, Duyckaerts C Hauw JJ: Correlation between microscopical changes and Tau 64 and 69 biochemical detection in senile dementia of the Alzheimer type. Tau 64 and 69 are reliable markers of the neurofibrillary degeneration. Acta Neuropathol (Berl) 1990;80:212-215.
    • (1990) Acta Neuropathol , vol.80 , pp. 212-215
    • Flament, S.1    Delacourte, A.2    Delaere, P.3    Duyckaerts, C.4    Hauw, J.J.5
  • 11
    • 0026454256 scopus 로고
    • Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease
    • Berl
    • Hof PR, Bouras C, Buee L, Delacourte A, Perl DP, Morrison JH: Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease. Acta Neuropathol (Berl) 1992;85:23-30.
    • (1992) Acta Neuropathol , vol.85 , pp. 23-30
    • Hof, P.R.1    Bouras, C.2    Buee, L.3    Delacourte, A.4    Perl, D.P.5    Morrison, J.H.6
  • 12
    • 0026458377 scopus 로고
    • Mapping of neurofibrillary degeneration in Alzheimer's disease: Evaluation of heterogeneity using the quantification of abnormal tau proteins
    • Berl
    • Vermersch P, Frigard B, Delacourte A: Mapping of neurofibrillary degeneration in Alzheimer's disease: Evaluation of heterogeneity using the quantification of abnormal tau proteins. Acta Neuropathol (Berl) 1992;85:48-54.
    • (1992) Acta Neuropathol , vol.85 , pp. 48-54
    • Vermersch, P.1    Frigard, B.2    Delacourte, A.3
  • 16
    • 0027984739 scopus 로고
    • Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein
    • Goedert M, Jakes R, Crowther RA, Cohen P, Vanmechelen E, Vandermeeren M, Cras P: Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein. Biochem J 1994;301:871-877.
    • (1994) Biochem J , vol.301 , pp. 871-877
    • Goedert, M.1    Jakes, R.2    Crowther, R.A.3    Cohen, P.4    Vanmechelen, E.5    Vandermeeren, M.6    Cras, P.7
  • 17
    • 0028946744 scopus 로고
    • Monoclonal antibody AT8 recognizes tau protein phosphorylated at both serine 202 and threonine 205
    • Goedert M, Jakes R, Vanmechelen E: Monoclonal antibody AT8 recognizes tau protein phosphorylated at both serine 202 and threonine 205. Neurosci Lett 1995;189:167-169.
    • (1995) Neurosci Lett , vol.189 , pp. 167-169
    • Goedert, M.1    Jakes, R.2    Vanmechelen, E.3
  • 18
    • 0024592795 scopus 로고
    • Tau protein immunoreactivity in dementia of the Alzheimer type. 2. Electron microscopy and pathogenetic implications. Effects of fixation on the morphology of the Alzheimer's abnormal filaments
    • Papasozomenos SC: Tau protein immunoreactivity in dementia of the Alzheimer type. 2. Electron microscopy and pathogenetic implications. Effects of fixation on the morphology of the Alzheimer's abnormal filaments. Lab Invest 1989;60:375-389.
    • (1989) Lab Invest , vol.60 , pp. 375-389
    • Papasozomenos, S.C.1
  • 19
    • 0023505501 scopus 로고
    • Phosphorylation determines two distinct species of tau in the central nervous system
    • Papasozomenos SC, Binder LI: Phosphorylation determines two distinct species of tau in the central nervous system. Cell Motil Cytoskeleton 1987;8:210-226.
    • (1987) Cell Motil Cytoskeleton , vol.8 , pp. 210-226
    • Papasozomenos, S.C.1    Binder, L.I.2
  • 21
    • 0029068246 scopus 로고
    • Rapid dephosphorylation of tau in heat-shocked fetal rat cerebral explants: Prevention and hyperphosphorylation by inhibitors of protein phosphatases PP1 and PP2A
    • Papasozomenos SC, Su Y: Rapid dephosphorylation of tau in heat-shocked fetal rat cerebral explants: Prevention and hyperphosphorylation by inhibitors of protein phosphatases PP1 and PP2A. J Neurochem 1995;65:396-406.
    • (1995) J Neurochem , vol.65 , pp. 396-406
    • Papasozomenos, S.C.1    Su, Y.2
  • 22
    • 0026512838 scopus 로고
    • Affinity purification of human tau proteins and the construction of a sensitive sandwich enzyme-linked immunosorbent assay for human tau detection
    • Mercken M, Vandermeeren M, Lubke U, Six J, Boons J, Vanmechelen E, Van de Voorde A, Gheuens J: Affinity purification of human tau proteins and the construction of a sensitive sandwich enzyme-linked immunosorbent assay for human tau detection. J Neurochem 1992;58:548-553.
    • (1992) J Neurochem , vol.58 , pp. 548-553
    • Mercken, M.1    Vandermeeren, M.2    Lubke, U.3    Six, J.4    Boons, J.5    Vanmechelen, E.6    Van De Voorde, A.7    Gheuens, J.8
  • 23
    • 0028362458 scopus 로고
    • A sequence of cytoskeletal changes related to the formation of neurofibrillary tangles and neuropil threads
    • Berl
    • Braak E, Braak H, Mandelkow EM: A sequence of cytoskeletal changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol (Berl) 1994;87:554-567.
    • (1994) Acta Neuropathol , vol.87 , pp. 554-567
    • Braak, E.1    Braak, H.2    Mandelkow, E.M.3
  • 24
    • 0034920989 scopus 로고    scopus 로고
    • Evolution from pretangle neurons to neurofibrillary tangles monitored by thiazin red combined with Gallyas method and double immunofluorescence
    • Berl
    • Uchihara T, Nakamura A, Yamazaki M, Mori O: Evolution from pretangle neurons to neurofibrillary tangles monitored by thiazin red combined with Gallyas method and double immunofluorescence. Acta Neuropathol (Berl) 2001;101:535-539.
    • (2001) Acta Neuropathol , vol.101 , pp. 535-539
    • Uchihara, T.1    Nakamura, A.2    Yamazaki, M.3    Mori, O.4
  • 25
    • 0025800101 scopus 로고
    • A silver impregnation method for labeling both Alzheimer paired helical filaments and their polypeptides separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis
    • Iqbal K, Braak E, Braak H, Zaidi T, Grundke-Iqbal I: A silver impregnation method for labeling both Alzheimer paired helical filaments and their polypeptides separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Neurobiol Aging 1991;12:357-361.
    • (1991) Neurobiol Aging , vol.12 , pp. 357-361
    • Iqbal, K.1    Braak, E.2    Braak, H.3    Zaidi, T.4    Grundke-Iqbal, I.5
  • 26
    • 0027759674 scopus 로고
    • Synergistic control mechanism for abnormal site phosphorylation of Alzheimer's disease brain tau by kinase FA/GSK-3 alpha
    • Yang SD, Yu JS, Liu WK, Yen SH: Synergistic control mechanism for abnormal site phosphorylation of Alzheimer's disease brain tau by kinase FA/GSK-3 alpha. Biochem Biophys Res Commun 1993;197:400-406.
    • (1993) Biochem Biophys Res Commun , vol.197 , pp. 400-406
    • Yang, S.D.1    Yu, J.S.2    Liu, W.K.3    Yen, S.H.4
  • 27
    • 0030067749 scopus 로고    scopus 로고
    • Non-proline-dependent protein kinases phosphorylate several sites found in tau from Alzheimer disease brain
    • Singh TJ, Zaidi T, Grundke-Iqbal I, Iqbal K: Non-proline-dependent protein kinases phosphorylate several sites found in tau from Alzheimer disease brain. Mol Cell Biochem 1996;154:143-151.
    • (1996) Mol Cell Biochem , vol.154 , pp. 143-151
    • Singh, T.J.1    Zaidi, T.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 28
    • 0029789213 scopus 로고    scopus 로고
    • Phosphorylation of native and truncated isoforms of protein tau by the double-stranded DNA-dependent protein kinase (DNA-PK) shows that the primary phosphorylation sites are localized between amino acid residues 212-231 of the longest tau
    • Wu JM, Chen Y, Hsieh TC, Brandt R, Lee G: Phosphorylation of native and truncated isoforms of protein tau by the double-stranded DNA-dependent protein kinase (DNA-PK) shows that the primary phosphorylation sites are localized between amino acid residues 212-231 of the longest tau. Biochem Mol Biol Int 1996;40:21-31.
    • (1996) Biochem Mol Biol Int , vol.40 , pp. 21-31
    • Wu, J.M.1    Chen, Y.2    Hsieh, T.C.3    Brandt, R.4    Lee, G.5
  • 29
    • 0032528393 scopus 로고    scopus 로고
    • Regional quantitative analysis of tau-positive neurons in supranuclear palsy: Comparison with Alzheimer's disease
    • Li F, Iseki E, Odawara T, Kosaka K, Yagishita S, Amano N: Regional quantitative analysis of tau-positive neurons in supranuclear palsy: Comparison with Alzheimer's disease. J Neurol Sci 1998;159:73-81.
    • (1998) J Neurol Sci , vol.159 , pp. 73-81
    • Li, F.1    Iseki, E.2    Odawara, T.3    Kosaka, K.4    Yagishita, S.5    Amano, N.6
  • 30
    • 0025327183 scopus 로고
    • Selective disconnection of specific visual association pathways in cases of Alzheimer's disease presenting with Balint's syndrome
    • Hof PR, Bouras C, Constantinidis J, Morrison JH: Selective disconnection of specific visual association pathways in cases of Alzheimer's disease presenting with Balint's syndrome. J Neuropathol Exp Neurol 1990;49:168-184.
    • (1990) J Neuropathol Exp Neurol , vol.49 , pp. 168-184
    • Hof, P.R.1    Bouras, C.2    Constantinidis, J.3    Morrison, J.H.4
  • 31
    • 0032544724 scopus 로고    scopus 로고
    • Alzheimer's disease with asymmetric parietal lobe atrophy: A case report
    • Kaida K, Takeda K, Nagata N, Kamakura K: Alzheimer's disease with asymmetric parietal lobe atrophy: A case report. J Neurol Sci 1998;160:96-99.
    • (1998) J Neurol Sci , vol.160 , pp. 96-99
    • Kaida, K.1    Takeda, K.2    Nagata, N.3    Kamakura, K.4
  • 32
    • 0036277902 scopus 로고    scopus 로고
    • Posterior cortical atrophy: Clinical characteristics and differences compared to Alzheimer's disease
    • Mendez MF, Ghajarania M, Perryman KM: Posterior cortical atrophy: Clinical characteristics and differences compared to Alzheimer's disease. Dement Geriatr Cogn Disord 2002;14: 33-40.
    • (2002) Dement Geriatr Cogn Disord , vol.14 , pp. 33-40
    • Mendez, M.F.1    Ghajarania, M.2    Perryman, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.