Development of a fluorescent indicator for nitric oxide based on the fluorescein chromophore

Chemical and Pharmaceutical Bulletin

Volumn 46, Issue 2, 1998, Pages 373-375

  Kojima, Hirotatsu ^a   Sakurai, Kuniko ^a   Kikuchi, Kazuya ^a   Kawahara, Shigenori ^a   Kirino, Yutaka ^a   Nagoshi, Hiroshi ^a   Hirata, Yasunobu ^a   Nagano, Tetsuo ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

Diaminofluorescein; Fluorescent indicator; Imaging; Nitric oxide; Vascular smooth muscle cell

Indexed keywords

4,5 DIAMINOFLUORESCEIN; FLUORESCEIN; NITRIC OXIDE; UNCLASSIFIED DRUG;

ARTICLE; CHROMATOPHORE; ENZYME ACTIVITY; FLUORESCENCE; MEMBRANE PERMEABILITY; PATHOPHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

EID: 0031940489     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.46.373     Document Type: Article

References (16)

1. Moncada S., Higgs A., N. Engl. J. Med., 329, 2002-2012 (1993).
2. Snyder S.H., Bredt D.S., Sci. Am., 266, 68-77 (1992).
3. Nathan C., Xie Q.W., Cell, 78, 915-918 (1994).
4. Malinski T., Mesaros S., Tomboulian P., Methods Enzymol., 268, 58-69 (1996).
5. Palmer R.M.J., Ferrige A.G., Moncada S., Nature (London), 327, 524-526 (1987).
6. Akaike T., Maeda H., Methods Enzymol., 268, 211-221 (1996).
7. Kikuchi K., Nagano T., Hayakawa H., Hirata Y., Hirobe M., J. Biol. Chem., 268, 23106-23110 (1993).
8. Minta A., Kao J.P.Y., Tsien R.Y., J. Biol. Chem., 264, 8171-8178 (1989).
9. Nagano T., Takizawa H., Hirobe M., Tetrahedron Lett., 36, 8239-8242 (1995).
10. Kojima H., Sakurai K., Kikuchi K., Kawahara S., Kirino Y., Nagoshi H., Hirata Y., Akaike T., Maeda H., Nagano T., Biol. Pharm. Bull., 20, 1229-1232 (1997).
11. Munkholm C., Parkinson D.-R., Walt D.R., J. Am. Chem. Soc., 112, 2608-2612 (1990).
12. 2O: C, 64.37; H, 4.11; N, 7.51. Found: C, 64.12; H, 4.00; N, 7.55.
13. +).
14. Nishikawa Y., Hiraki K., "Analytical Methods of Fluorescence and Phosphorescence," ed. by the Japan Society for Analytical Chemistry, Kyoritsu Publishing Company, Tokyo, 1984, pp. 76-80.
15. 7: C, 64.57; H, 4.06; N, 6.28. Found: C, 64.27; H, 4.16; N, 6.18.
16. Rotman B., Papermaster B.W., Proc. Natl. Acad. Sci. USA, 55, 134-141 (1966).