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Volumn 7, Issue 14, 2006, Pages 1857-1869

Clinical application of pharmacogenetics in gastrointestinal diseases

Author keywords

Drug metabolism; Drug toxicity; Pharmacogenetics; Pharmacogenomics; Polymophisms

Indexed keywords

ALOSETRON; ANTACID AGENT; ANTIBIOTIC AGENT; AZATHIOPRINE; BISMUTH SALT; BUSPIRONE; CASPASE RECRUITMENT DOMAIN PROTEIN 15; CORTICOSTEROID; CYCLOSPORIN; DIPHENOXYLATE; DRUG METABOLIZING ENZYME; FLUOROURACIL; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; LOPERAMIDE; MERCAPTOPURINE; MESALAZINE; METHOTREXATE; NITRATE; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISONE; PROTON PUMP INHIBITOR; RABEPRAZOLE; SEROTONIN TRANSPORTER; SPASMOLYTIC AGENT; TACROLIMUS; TEGASEROD; TRICYCLIC ANTIDEPRESSANT AGENT; UNINDEXED DRUG;

EID: 33749332041     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.7.14.1857     Document Type: Review
Times cited : (5)

References (106)
  • 1
    • 2442563304 scopus 로고    scopus 로고
    • Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
    • LOFTUS EV Jr: Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology (2004) 126(6):1504-1517.
    • (2004) Gastroenterology , vol.126 , Issue.6 , pp. 1504-1517
    • Loftus Jr., E.V.1
  • 3
    • 0038534797 scopus 로고    scopus 로고
    • The CARD15 (also known as NOD2) gene in Crohn's disease: Are there implications for current clinical practice?
    • COLOMBEL JF: The CARD15 (also known as NOD2) gene in Crohn's disease: are there implications for current clinical practice? Clin. Gastroenterol. Hepatol. (2003) 1(1):5-9.
    • (2003) Clin. Gastroenterol. Hepatol. , vol.1 , Issue.1 , pp. 5-9
    • Colombel, J.F.1
  • 4
    • 0028267896 scopus 로고
    • Frequency of glucocorticoid resistance and dependency in Crohn's disease
    • MUNKHOLM P, LANGHOLZ E, DAVIDSEN M, BINDER V: Frequency of glucocorticoid resistance and dependency in Crohn's disease. Gut (1994) 35(3):360-362.
    • (1994) Gut , vol.35 , Issue.3 , pp. 360-362
    • Munkholm, P.1    Langholz, E.2    Davidsen, M.3    Binder, V.4
  • 5
    • 0034903792 scopus 로고    scopus 로고
    • The natural history of corticosteroid therapy for inflammatory bowel disease: A population-based study
    • FAUBION WA Jr, LOFTUS EV Jr, HARMSEN WS, ZINSMEISTER AR, SANDBORN WJ: The natural history of corticosteroid therapy for inflammatory bowel disease: a population-based study. Gastroenterology (2001) 121(2):255-260.
    • (2001) Gastroenterology , vol.121 , Issue.2 , pp. 255-260
    • Faubion Jr., W.A.1    Loftus Jr., E.V.2    Harmsen, W.S.3    Zinsmeister, A.R.4    Sandborn, W.J.5
  • 6
    • 4444224484 scopus 로고    scopus 로고
    • Azathioprine, 6-mercaptopurine in inflammatory bowel disease: Pharmacology, efficacy, and safety
    • DUBINSKY MC: Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol. Hepatol. (2004) 2(9):731-743.
    • (2004) Clin Gastroenterol. Hepatol. , vol.2 , Issue.9 , pp. 731-743
    • Dubinsky, M.C.1
  • 7
    • 2942594260 scopus 로고    scopus 로고
    • Treatment of inflammatory bowel disease with azathioprine and 6-mercaptopurine
    • viii
    • SU C, LICHTENSTEIN GR: Treatment of inflammatory bowel disease with azathioprine and 6-mercaptopurine. Gastroenterol. Clin. North Am. (2004) 33(2):209-234, viii.
    • (2004) Gastroenterol. Clin. North Am. , vol.33 , Issue.2 , pp. 209-234
    • Su, C.1    Lichtenstein, G.R.2
  • 8
    • 0030986251 scopus 로고    scopus 로고
    • Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): Mechanisms for the genetic polymorphism of TPMT activity
    • TAI HL, KRYNETSKI EY, SCHUETZ EG, YANISHEVSKI Y, EVANS WE: Enhanced proteolysis of thiopurine S-methyltransferase (TPMT) encoded by mutant alleles in humans (TPMT*3A, TPMT*2): mechanisms for the genetic polymorphism of TPMT activity. Proc. Natl Acad. Sci. USA (1997) 94(12):6444-6449.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , Issue.12 , pp. 6444-6449
    • Tai, H.L.1    Krynetski, E.Y.2    Schuetz, E.G.3    Yanishevski, Y.4    Evans, W.E.5
  • 9
    • 1142273254 scopus 로고    scopus 로고
    • A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations
    • ROBERTS RL, BARCLAY ML, GEARRY RB, KENNEDY MA: A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine S-methyltransferase (TPMT) mutations. Clin. Chim. Acta (2004) 341(1-2):49-53.
    • (2004) Clin. Chim. Acta , vol.341 , Issue.1-2 , pp. 49-53
    • Roberts, R.L.1    Barclay, M.L.2    Gearry, R.B.3    Kennedy, M.A.4
  • 10
    • 0018822866 scopus 로고
    • Mercaptopurine pharmacogenetics: Monogenic inheritance of erythrocyte thiopurine methyltransferase activity
    • WEINSHILBOUM RM, SLADEK SL: Mercaptopurine pharmacogenetics: monogenic inheritance of erythrocyte thiopurine methyltransferase activity. Am. J. Hum. Genet. (1980) 32(5):651-662.
    • (1980) Am. J. Hum. Genet. , vol.32 , Issue.5 , pp. 651-662
    • Weinshilboum, R.M.1    Sladek, S.L.2
  • 11
    • 4644241129 scopus 로고    scopus 로고
    • Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease
    • WINTER J, WALKER A, SHAPIRO D et al.: Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease. Aliment. Pharmacol. Ther. (2004) 20(6):593-599.
    • (2004) Aliment. Pharmacol. Ther. , vol.20 , Issue.6 , pp. 593-599
    • Winter, J.1    Walker, A.2    Shapiro, D.3
  • 12
    • 0034093057 scopus 로고    scopus 로고
    • Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy
    • COLOMBEL JF, FERRARI N, DEBUYSERE H et al.: Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy. Gastroenterology (2000) 118(6):1025-1030.
    • (2000) Gastroenterology , vol.118 , Issue.6 , pp. 1025-1030
    • Colombel, J.F.1    Ferrari, N.2    Debuysere, H.3
  • 13
    • 33644855102 scopus 로고    scopus 로고
    • American Gastroenterological Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease
    • LICHTENSTEIN GR, ABREU MT, COHEN R, TREMAINE W: American Gastroenterological Association Institute medical position statement on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease. Gastroenterology (2006) 130(3):935-939.
    • (2006) Gastroenterology , vol.130 , Issue.3 , pp. 935-939
    • Lichtenstein, G.R.1    Abreu, M.T.2    Cohen, R.3    Tremaine, W.4
  • 14
    • 33749366573 scopus 로고    scopus 로고
    • Azathioprine
    • In: Thomson MICROMEDEX® Healthcare Series
    • Azathioprine. In: Physicians Desk Reference. Thomson MICROMEDEX® Healthcare Series, Vol 129(2006).
    • (2006) Physicians Desk Reference , vol.129
  • 15
    • 0035412398 scopus 로고    scopus 로고
    • Pharmacogenetics of methotrexate: Toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism
    • ULRICH CM, YASUI Y, STORB R et al.: Pharmacogenetics of methotrexate: toxicity among marrow transplantation patients varies with the methylenetetrahydrofolate reductase C677T polymorphism. Blood (2001) 98(1):231-234.
    • (2001) Blood , vol.98 , Issue.1 , pp. 231-234
    • Ulrich, C.M.1    Yasui, Y.2    Storb, R.3
  • 16
    • 0036263469 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses
    • URANO W, TANIGUCHI A, YAMANAKA H et al.: Polymorphisms in the methylenetetrahydrofolate reductase gene were associated with both the efficacy and the toxicity of methotrexate used for the treatment of rheumatoid arthritis, as evidenced by single locus and haplotype analyses. Pharmacogenetics (2002) 12(3):183-190.
    • (2002) Pharmacogenetics , vol.12 , Issue.3 , pp. 183-190
    • Urano, W.1    Taniguchi, A.2    Yamanaka, H.3
  • 17
    • 0036820724 scopus 로고    scopus 로고
    • Genetic basis, of inosine triphosphate pyrophosphohydrolase deficiency
    • SUMI S, MARINAKI AM, ARENAS M et al.: Genetic basis, of inosine triphosphate pyrophosphohydrolase deficiency. Hum. Genet. (2002) 111(4-5):360-367.
    • (2002) Hum. Genet. , vol.111 , Issue.4-5 , pp. 360-367
    • Sumi, S.1    Marinaki, A.M.2    Arenas, M.3
  • 18
    • 12144285961 scopus 로고    scopus 로고
    • Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase)
    • MARINAKI AM, ANSARI A, DULEY JA et al.: Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase). Pharmacogenetics (2004) 14(3):181-187.
    • (2004) Pharmacogenetics , vol.14 , Issue.3 , pp. 181-187
    • Marinaki, A.M.1    Ansari, A.2    Duley, J.A.3
  • 19
    • 9244237558 scopus 로고    scopus 로고
    • Lack of association between the ITPA 94C > A polymorphism and adverse effects from azathioprine
    • GEARRY RB, ROBERTS RL, BARCLAY ML, KENNEDY MA: Lack of association between the ITPA 94C > A polymorphism and adverse effects from azathioprine. Pharmacogenetics (2004) 14(11):779-781.
    • (2004) Pharmacogenetics , vol.14 , Issue.11 , pp. 779-781
    • Gearry, R.B.1    Roberts, R.L.2    Barclay, M.L.3    Kennedy, M.A.4
  • 20
    • 15444367938 scopus 로고    scopus 로고
    • ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression
    • ALLORGE D, HAMDAN R, BROLY F, LIBERSA C, COLOMBEL JF: ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression. Gut (2005) 54(4):565-568.
    • (2005) Gut , vol.54 , Issue.4 , pp. 565-568
    • Allorge, D.1    Hamdan, R.2    Broly, F.3    Libersa, C.4    Colombel, J.F.5
  • 21
    • 27444437058 scopus 로고    scopus 로고
    • ITPA genotyping is not predictive for the development of side effects in AZA treated inflammatory bowel disease patients
    • VAN DIEREN JM, VAN VUUREN AJ, KUSTERS JG et al.: ITPA genotyping is not predictive for the development of side effects in AZA treated inflammatory bowel disease patients. Gut (2005) 54(11):1664.
    • (2005) Gut , vol.54 , Issue.11 , pp. 1664
    • van Dieren, J.M.1    van Vuuren, A.J.2    Kusters, J.G.3
  • 22
    • 0036310989 scopus 로고    scopus 로고
    • N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis
    • RICART E, TAYLOR WR, LOFTUS EV et al.: N-acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis. Am. J. Gastroenterol. (2002) 97(7):1763-1768.
    • (2002) Am. J. Gastroenterol. , vol.97 , Issue.7 , pp. 1763-1768
    • Ricart, E.1    Taylor, W.R.2    Loftus, E.V.3
  • 23
    • 1842835884 scopus 로고    scopus 로고
    • Pharmacogenomics of response to anti-tumor necrosis factor therapy in patients with Crohn's disease
    • SHETTY A, FORBES A: Pharmacogenomics of response to anti-tumor necrosis factor therapy in patients with Crohn's disease. Am. J. Pharmacogenomics (2002) 2(4):215-221.
    • (2002) Am. J. Pharmacogenomics , vol.2 , Issue.4 , pp. 215-221
    • Shetty, A.1    Forbes, A.2
  • 24
    • 0035988896 scopus 로고    scopus 로고
    • A positive response to infliximab in Crohn disease: Association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism
    • LOUIS E, VERMEIRE S, RUTGEERTS P et al.: A positive response to infliximab in Crohn disease: association with a higher systemic inflammation before treatment but not with -308 TNF gene polymorphism. Scand J. Gastroenterol. (2002) 37(7):818-824.
    • (2002) Scand J. Gastroenterol. , vol.37 , Issue.7 , pp. 818-824
    • Louis, E.1    Vermeire, S.2    Rutgeerts, P.3
  • 25
    • 0036367145 scopus 로고    scopus 로고
    • Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab
    • MASCHERETTI S, HAMPE J, KUHBACHER T et al.: Pharmacogenetic investigation of the TNF/TNF-receptor system in patients with chronic active Crohn's disease treated with infliximab. Pharmacogenomics J. (2002) 2(2):127-136.
    • (2002) Pharmacogenomics J. , vol.2 , Issue.2 , pp. 127-136
    • Mascheretti, S.1    Hampe, J.2    Kuhbacher, T.3
  • 26
    • 18644366895 scopus 로고    scopus 로고
    • Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: An analysis in 534 patients from two multicenter, prospective GCP-level trials NOD2/CARD15 does not influence response to infliximab in Crohn's disease
    • MASCHERETTI S, HAMPE J, CROUCHER PJ et al.: Response to infliximab treatment in Crohn's disease is not associated with mutations in the CARD15 (NOD2) gene: an analysis in 534 patients from two multicenter, prospective GCP-level trials NOD2/CARD15 does not influence response to infliximab in Crohn's disease. Pharmacogenetics (2002) 12(7):509-515.
    • (2002) Pharmacogenetics , vol.12 , Issue.7 , pp. 509-515
    • Mascheretti, S.1    Hampe, J.2    Croucher, P.J.3
  • 27
    • 0036305537 scopus 로고    scopus 로고
    • NOD2/CARD15 does not influence response to infliximab in Crohn's disease
    • VERMEIRE S, LOUIS E, RUTGEERTS P et al.: NOD2/CARD15 does not influence response to infliximab in Crohn's disease. Gastroenterology (2002) 123(1):106-111.
    • (2002) Gastroenterology , vol.123 , Issue.1 , pp. 106-111
    • Vermeire, S.1    Louis, E.2    Rutgeerts, P.3
  • 28
    • 0030931230 scopus 로고    scopus 로고
    • Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota
    • LOCKE GR III, TALLEY NJ, FETT SL, ZINSMEISTER AR, MELTON LJ III: Prevalence and clinical spectrum of gastroesophageal reflux: a population-based study in Olmsted County, Minnesota. Gastroenterology (1997) 112(5):1448-1456.
    • (1997) Gastroenterology , vol.112 , Issue.5 , pp. 1448-1456
    • Locke III, G.R.1    Talley, N.J.2    Fett, S.L.3    Zinsmeister, A.R.4    Melton III, L.J.5
  • 29
    • 0031031977 scopus 로고    scopus 로고
    • Meta-analysis of risk factors for peptic ulcer. Nonsteroidal antiinflammatory drugs, Helicobacter pylori, and smoking
    • KURATA JH, NOGAWA AN: Meta-analysis of risk factors for peptic ulcer. Nonsteroidal antiinflammatory drugs, Helicobacter pylori, and smoking. J. Clin. Gastroenterol. (1997) 24(1):2-17.
    • (1997) J. Clin. Gastroenterol. , vol.24 , Issue.1 , pp. 2-17
    • Kurata, J.H.1    Nogawa, A.N.2
  • 30
    • 0029076049 scopus 로고
    • The prevalence of Helicobacter pylori infection in different countries
    • POUNDER RE, NG D: The prevalence of Helicobacter pylori infection in different countries. Aliment. Pharmacol. Ther. (1995) 9(Suppl. 2):33-39.
    • (1995) Aliment. Pharmacol. Ther. , vol.9 , Issue.SUPPL. 2 , pp. 33-39
    • Pounder, R.E.1    Ng, D.2
  • 31
    • 0024208785 scopus 로고
    • Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori
    • MARSHALL BJ, GOODWIN CS, WARREN JR et al.: Prospective double-blind trial of duodenal ulcer relapse after eradication of Campylobacter pylori. Lancet (1988) 2(8626-8627):1437-1442.
    • (1988) Lancet , vol.2 , Issue.8626-8627 , pp. 1437-1442
    • Marshall, B.J.1    Goodwin, C.S.2    Warren, J.R.3
  • 32
    • 0025331686 scopus 로고
    • Cure of duodenal ulcer associated with eradication of Helicobacter pylori
    • RAUWS EA, TYTGAT GN: Cure of duodenal ulcer associated with eradication of Helicobacter pylori. Lancet (1990) 335(8700):1233-1235.
    • (1990) Lancet , vol.335 , Issue.8700 , pp. 1233-1235
    • Rauws, E.A.1    Tytgat, G.N.2
  • 33
    • 0034972797 scopus 로고    scopus 로고
    • Management of heartburn in a large, randomized, community-based study: Comparison of four therapeutic strategies
    • HOWDEN CW, HENNING JM, HUANG B, LUKASIK N, FRESTON JW: Management of heartburn in a large, randomized, community-based study: comparison of four therapeutic strategies. Am. J. Gastroenterol. (2001) 96(6):1704-1710.
    • (2001) Am. J. Gastroenterol. , vol.96 , Issue.6 , pp. 1704-1710
    • Howden, C.W.1    Henning, J.M.2    Huang, B.3    Lukasik, N.4    Freston, J.W.5
  • 34
    • 4444260652 scopus 로고    scopus 로고
    • Efficacy and safety of pantoprazole versus ranitidine in the treatment of patients with symptomatic gastroesophageal reflux disease
    • VAN ZYL J, VAN RENSBURG C, VIEWEG W, FISCHER R: Efficacy and safety of pantoprazole versus ranitidine in the treatment of patients with symptomatic gastroesophageal reflux disease. Digestion (2004) 70(1):61-69.
    • (2004) Digestion , vol.70 , Issue.1 , pp. 61-69
    • van Zyl, J.1    van Rensburg, C.2    Vieweg, W.3    Fischer, R.4
  • 35
    • 0033885191 scopus 로고    scopus 로고
    • Rabeprazole versus ranitidine for the treatment of erosive gastroesophageal reflux disease: A double-blind, randomized clinical trial
    • Raberprazole Study Group
    • FARLEY A, WRUBLE LD, HUMPHRIES TJ: Rabeprazole versus ranitidine for the treatment of erosive gastroesophageal reflux disease: a double-blind, randomized clinical trial. Raberprazole Study Group. Am. J. Gastroenterol. (2000) 95(8):1894-1899.
    • (2000) Am. J. Gastroenterol. , vol.95 , Issue.8 , pp. 1894-1899
    • Farley, A.1    Wruble, L.D.2    Humphries, T.J.3
  • 36
    • 0034717520 scopus 로고    scopus 로고
    • Lansoprazole compared with ranitidine for the treatment of nonerosive gastroesophageal reflux disease
    • RICHTER JE, CAMPBELL DR, KAHRILAS PJ, HUANG B, FLUDAS C: Lansoprazole compared with ranitidine for the treatment of nonerosive gastroesophageal reflux disease. Arch. Intern. Med. (2000) 160(12):1803-1809.
    • (2000) Arch. Intern. Med. , vol.160 , Issue.12 , pp. 1803-1809
    • Richter, J.E.1    Campbell, D.R.2    Kahrilas, P.J.3    Huang, B.4    Fludas, C.5
  • 38
    • 0642379417 scopus 로고    scopus 로고
    • Different contribution of CYP2C19 in the in vitro metabolism of three proton pump inhibitors
    • KITA T, SAKAEDA T, BABA T et al.: Different contribution of CYP2C19 in the in vitro metabolism of three proton pump inhibitors. Biol. Pharm. Bull. (2003) 26(3):386-390.
    • (2003) Biol. Pharm. Bull. , vol.26 , Issue.3 , pp. 386-390
    • Kita, T.1    Sakaeda, T.2    Baba, T.3
  • 39
    • 0032807774 scopus 로고    scopus 로고
    • Review article: Cytochrome P450 and the metabolism of proton pump inhibitors-emphasis on rabeprazole
    • ISHIZAKI T, HORAI Y: Review article: cytochrome P450 and the metabolism of proton pump inhibitors-emphasis on rabeprazole. Aliment. Pharmacol. Ther. (1999) 13(Suppl. 3):27-36.
    • (1999) Aliment. Pharmacol. Ther. , vol.13 , Issue.SUPPL. 3 , pp. 27-36
    • Ishizaki, T.1    Horai, Y.2
  • 40
    • 0028260641 scopus 로고
    • The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans
    • DE MORAIS SM, WILKINSON GR, BLAISDELL J et al.: The major genetic defect responsible for the polymorphism of S-mephenytoin metabolism in humans. J. Biol. Chem. (1994) 269(22):15419-15422.
    • (1994) J. Biol. Chem. , vol.269 , Issue.22 , pp. 15419-15422
    • De Morais, S.M.1    Wilkinson, G.R.2    Blaisdell, J.3
  • 41
    • 0028044085 scopus 로고
    • Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese
    • DE MORAIS SM, WILKINSON GR, BLAISDELL J et al.: Identification of a new genetic defect responsible for the polymorphism of (S)-mephenytoin metabolism in Japanese. Mol. Pharmacol. (1994) 46(4):594-598.
    • (1994) Mol. Pharmacol. , vol.46 , Issue.4 , pp. 594-598
    • De Morais, S.M.1    Wilkinson, G.R.2    Blaisdell, J.3
  • 42
    • 15444340367 scopus 로고    scopus 로고
    • A new genetic defect in human CYP2C19: Mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin
    • FERGUSON RJ, DE MORAIS SM, BENHAMOU S et al.: A new genetic defect in human CYP2C19: mutation of the initiation codon is responsible for poor metabolism of S-mephenytoin. J. Pharmacol. Exp. Ther. (1998) 284(1):356-361.
    • (1998) J. Pharmacol. Exp. Ther. , vol.284 , Issue.1 , pp. 356-361
    • Ferguson, R.J.1    De Morais, S.M.2    Benhamou, S.3
  • 43
    • 15644372745 scopus 로고    scopus 로고
    • An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians
    • IBEANU GC, BLAISDELL J, GHANAYEM BI et al.: An additional defective allele, CYP2C19*5, contributes to the S-mephenytoin poor metabolizer phenotype in Caucasians. Pharmacogenetics (1998) 8(2):129-135.
    • (1998) Pharmacogenetics , vol.8 , Issue.2 , pp. 129-135
    • Ibeanu, G.C.1    Blaisdell, J.2    Ghanayem, B.I.3
  • 44
    • 12244261584 scopus 로고    scopus 로고
    • Identification and functional characterization of new potentially defective alleles of human CYP2C19
    • BLAISDELL J, MOHRENWEISER H, JACKSON J et al.: Identification and functional characterization of new potentially defective alleles of human CYP2C19. Pharmacogenetics (2002) 12(9):703-711.
    • (2002) Pharmacogenetics , vol.12 , Issue.9 , pp. 703-711
    • Blaisdell, J.1    Mohrenweiser, H.2    Jackson, J.3
  • 45
    • 0036795262 scopus 로고    scopus 로고
    • Effect of cytochrome P4502C19 genotypic differences on cure rates for gastroesophageal reflux disease by lansoprazole
    • FURUTA T, SHIRAI N, WATANABE F et al.: Effect of cytochrome P4502C19 genotypic differences on cure rates for gastroesophageal reflux disease by lansoprazole. Clin. Pharmacol. Ther. (2002) 72(4):453-460.
    • (2002) Clin. Pharmacol. Ther. , vol.72 , Issue.4 , pp. 453-460
    • Furuta, T.1    Shirai, N.2    Watanabe, F.3
  • 46
    • 0037392311 scopus 로고    scopus 로고
    • The effects of lansoprazole on erosive reflux oesophagitis are influenced by CYP2C19 polymorphism
    • KAWAMURA M, OHARA S, KOIKE T et al.: The effects of lansoprazole on erosive reflux oesophagitis are influenced by CYP2C19 polymorphism. Aliment. Pharmacol. Ther. (2003) 17(7):965-973.
    • (2003) Aliment. Pharmacol. Ther. , vol.17 , Issue.7 , pp. 965-973
    • Kawamura, M.1    Ohara, S.2    Koike, T.3
  • 47
    • 0037380492 scopus 로고    scopus 로고
    • Pharmacogenetics of the proton pump inhibitors: A systematic review
    • CHONG E, ENSOM MH: Pharmacogenetics of the proton pump inhibitors: a systematic review. Pharmacotherapy (2003) 23(4):460-471.
    • (2003) Pharmacotherapy , vol.23 , Issue.4 , pp. 460-471
    • Chong, E.1    Ensom, M.H.2
  • 48
    • 3342997410 scopus 로고    scopus 로고
    • CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazole-based quadruple therapy for eradication of Helicobacter pylori
    • SCHWAB M, SCHAEFFELER E, KLOTZ U, TREIBER G: CYP2C19 polymorphism is a major predictor of treatment failure in white patients by use of lansoprazole-based quadruple therapy for eradication of Helicobacter pylori. Clin. Pharmacol. Ther. (2004) 76(3):201-209.
    • (2004) Clin. Pharmacol. Ther. , vol.76 , Issue.3 , pp. 201-209
    • Schwab, M.1    Schaeffeler, E.2    Klotz, U.3    Treiber, G.4
  • 49
    • 33745611767 scopus 로고    scopus 로고
    • The AmpliChip CYP450 test: Principles, challenges, and future clinical utility in digestive disease
    • JURAN B, EGAN L, LAZARIDIS K: The AmpliChip CYP450 test: principles, challenges, and future clinical utility in digestive disease. Clin Gastroenterol. Hepatol. (2006) 4(7):822-830.
    • (2006) Clin Gastroenterol. Hepatol. , vol.4 , Issue.7 , pp. 822-830
    • Juran, B.1    Egan, L.2    Lazaridis, K.3
  • 50
    • 0036678922 scopus 로고    scopus 로고
    • The epidemiology of irritable bowel syndrome in North America: A systematic review
    • SAITO YA, SCHOENFELD P, LOCKE GR III: The epidemiology of irritable bowel syndrome in North America: a systematic review. Am. J. Gastroenterol. (2002) 97(8):1910-1915.
    • (2002) Am. J. Gastroenterol. , vol.97 , Issue.8 , pp. 1910-1915
    • Saito, Y.A.1    Schoenfeld, P.2    Locke III, G.R.3
  • 51
    • 0036718364 scopus 로고    scopus 로고
    • A comparison of office-based physician visits for irritable bowel syndrome and for migraine and asthma
    • KOZMA CM, BARGHOUT V, SLATON T, FRECH F, REEDER CE: A comparison of office-based physician visits for irritable bowel syndrome and for migraine and asthma. Manag. Care Interface (2002) 15(9):40-43, 49.
    • (2002) Manag. Care Interface , vol.15 , Issue.9 , pp. 49
    • Kozma, C.M.1    Barghout, V.2    Slaton, T.3    Frech, F.4    Reeder, C.E.5
  • 53
    • 10644290207 scopus 로고    scopus 로고
    • Review article: Serotonin receptors and transporters - Roles in normal and abnormal gastrointestinal motility
    • GERSHON MD: Review article: serotonin receptors and transporters - roles in normal and abnormal gastrointestinal motility. Aliment. Pharmacol. Ther. (2004) 20(Suppl. 7):3-14.
    • (2004) Aliment. Pharmacol. Ther. , vol.20 , Issue.SUPPL. 7 , pp. 3-14
    • Gershon, M.D.1
  • 54
    • 0034821162 scopus 로고    scopus 로고
    • Gender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndrome
    • VIRAMONTES BE, CAMILLERI M, MCKINZIE S et al.: Gender-related differences in slowing colonic transit by a 5-HT3 antagonist in subjects with diarrhea-predominant irritable bowel syndrome. Am. J. Gastroenterol. (2001) 96(9):2671-2676.
    • (2001) Am. J. Gastroenterol. , vol.96 , Issue.9 , pp. 2671-2676
    • Viramontes, B.E.1    Camilleri, M.2    McKinzie, S.3
  • 55
    • 0035882382 scopus 로고    scopus 로고
    • Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: Abnormal intestinal motility and the expression of cation transporters
    • CHEN JJ, LI Z, PAN H et al.: Maintenance of serotonin in the intestinal mucosa and ganglia of mice that lack the high-affinity serotonin transporter: abnormal intestinal motility and the expression of cation transporters. J. Neurosci. (2001) 21(16):6348-6361.
    • (2001) J. Neurosci. , vol.21 , Issue.16 , pp. 6348-6361
    • Chen, J.J.1    Li, Z.2    Pan, H.3
  • 56
    • 0028174014 scopus 로고
    • Organization of the human serotonin transporter gene
    • LESCH KP, BALLING U, GROSS J et al.: Organization of the human serotonin transporter gene. J. Neural Transm. Gen. Sect. (1994) 95(2):157-162.
    • (1994) J. Neural Transm. Gen. Sect. , vol.95 , Issue.2 , pp. 157-162
    • Lesch, K.P.1    Balling, U.2    Gross, J.3
  • 57
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • LESCH KP, BENGEL D, HEILS A et al.: Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science (1996) 274(5292):1527-1531.
    • (1996) Science , vol.274 , Issue.5292 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 58
    • 2442677620 scopus 로고    scopus 로고
    • Association of distinct alpha(2) adrenoceptor and serotonin transporter polymorphisms with constipation and somatic symptoms in functional gastrointestinal disorders
    • KIM HJ, CAMILLERI M, CARLSON PJ et al.: Association of distinct alpha(2) adrenoceptor and serotonin transporter polymorphisms with constipation and somatic symptoms in functional gastrointestinal disorders. Gut (2004) 53(6):829-837.
    • (2004) Gut , vol.53 , Issue.6 , pp. 829-837
    • Kim, H.J.1    Camilleri, M.2    Carlson, P.J.3
  • 59
    • 4644293513 scopus 로고    scopus 로고
    • Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women
    • YEO A, BOYD P, LUMSDEN S et al.: Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women. Gut (2004) 53(10):1452-1458.
    • (2004) Gut , vol.53 , Issue.10 , pp. 1452-1458
    • Yeo, A.1    Boyd, P.2    Lumsden, S.3
  • 60
    • 0036310957 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism in irritable bowel syndrome
    • PATA C, ERDAL ME, DERICI E et al.: Serotonin transporter gene polymorphism in irritable bowel syndrome. Am. J. Gastroenterol. (2002) 97(7):1780-1784.
    • (2002) Am. J. Gastroenterol. , vol.97 , Issue.7 , pp. 1780-1784
    • Pata, C.1    Erdal, M.E.2    Derici, E.3
  • 61
    • 4644226729 scopus 로고    scopus 로고
    • Serotonin transporter gene polymorphism in healthy adults and patients with irritable bowel syndrome
    • LEE DY, PARK H, KIM WH et al.: [Serotonin transporter gene polymorphism in healthy adults and patients with irritable bowel syndrome]. Korean J. Gastroenterol. (2004) 43(1):18-22.
    • (2004) Korean J. Gastroenterol. , vol.43 , Issue.1 , pp. 18-22
    • Lee, D.Y.1    Park, H.2    Kim, W.H.3
  • 62
    • 0036325415 scopus 로고    scopus 로고
    • Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome
    • CAMILLERI M, ATANASOVA E, CARLSON PJ et al.: Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome. Gastroenterology (2002) 123(2):425-432.
    • (2002) Gastroenterology , vol.123 , Issue.2 , pp. 425-432
    • Camilleri, M.1    Atanasova, E.2    Carlson, P.J.3
  • 63
    • 5144221172 scopus 로고    scopus 로고
    • Pathophysiology and treatment of functional dyspepsia
    • TACK J, BISSCHOPS R, SARNELLI G: Pathophysiology and treatment of functional dyspepsia. Gastroenterology (2004) 127(4):1239-1255.
    • (2004) Gastroenterology , vol.127 , Issue.4 , pp. 1239-1255
    • Tack, J.1    Bisschops, R.2    Sarnelli, G.3
  • 64
    • 10744222550 scopus 로고    scopus 로고
    • Association between a G-protein beta3 subunit gene polymorphism and the symptomatology and treatment responses of major depressive disorders
    • LEE HJ, CHA JH, HAM BJ et al.: Association between a G-protein beta3 subunit gene polymorphism and the symptomatology and treatment responses of major depressive disorders. Pharmacogenomics J. (2004) 4(1):29-33.
    • (2004) Pharmacogenomics J. , vol.4 , Issue.1 , pp. 29-33
    • Lee, H.J.1    Cha, J.H.2    Ham, B.J.3
  • 65
    • 0037675120 scopus 로고    scopus 로고
    • G-protein beta3 subunit 825T allele and hypertension
    • SIFFERT W: G-protein beta3 subunit 825T allele and hypertension. Curr. Hypertens. Rep. (2003) 5(1):47-53.
    • (2003) Curr. Hypertens. Rep. , vol.5 , Issue.1 , pp. 47-53
    • Siffert, W.1
  • 66
    • 0032794634 scopus 로고    scopus 로고
    • Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals
    • SIFFERT W, FORSTER P, JOCKEL KH et al.: Worldwide ethnic distribution of the G protein beta3 subunit 825T allele and its association with obesity in Caucasian, Chinese, and Black African individuals. J. Am. Soc. Nephrol. (1999) 10(9):1921-1930.
    • (1999) J. Am. Soc. Nephrol. , vol.10 , Issue.9 , pp. 1921-1930
    • Siffert, W.1    Forster, P.2    Jockel, K.H.3
  • 67
    • 0035917315 scopus 로고    scopus 로고
    • The G protein beta3 subunit 825T allele is a genetic marker for enhanced T cell response
    • LINDEMANN M, VIRCHOW S, RAMANN F et al.: The G protein beta3 subunit 825T allele is a genetic marker for enhanced T cell response. FEBS Lett. (2001) 495(1-2):82-86.
    • (2001) FEBS Lett. , vol.495 , Issue.1-2 , pp. 82-86
    • Lindemann, M.1    Virchow, S.2    Ramann, F.3
  • 68
    • 0032475894 scopus 로고    scopus 로고
    • Enhanced fMLP-stimulated chemotaxis in human neutrophils from individuals carrying the G protein beta3 subunit 825 T-allele
    • VIRCHOW S, ANSORGE N, RUBBEN H, SIFFERT G, SIFFERT W: Enhanced fMLP-stimulated chemotaxis in human neutrophils from individuals carrying the G protein beta3 subunit 825 T-allele. FEBS Lett. (1998) 436(2):155-158.
    • (1998) FEBS Lett. , vol.436 , Issue.2 , pp. 155-158
    • Virchow, S.1    Ansorge, N.2    Rubben, H.3    Siffert, G.4    Siffert, W.5
  • 69
    • 1842583755 scopus 로고    scopus 로고
    • G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia
    • HOLTMANN G, SIFFERT W, HAAG S et al.: G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia. Gastroenterology (2004) 126(4):971-979.
    • (2004) Gastroenterology , vol.126 , Issue.4 , pp. 971-979
    • Holtmann, G.1    Siffert, W.2    Haag, S.3
  • 70
    • 33644774923 scopus 로고    scopus 로고
    • A study of candidate genotypes associated with dyspepsia in a US community
    • In Press
    • CAMILLERI CE, CARLSON PJ, CAMILLERI M et al.: A study of candidate genotypes associated with dyspepsia in a US community. Am. J. Gastroenterol. (2006) In Press.
    • (2006) Am. J. Gastroenterol.
    • Camilleri, C.E.1    Carlson, P.J.2    Camilleri, M.3
  • 71
    • 2342639208 scopus 로고    scopus 로고
    • G-protein mediated receptor-cell-coupling as a predictor for the long term response to treatment in patients with functional dyspepsia
    • HOLTMANN G, SIFFERT W, GROTE E et al.: G-protein mediated receptor-cell-coupling as a predictor for the long term response to treatment in patients with functional dyspepsia. Gastroenterology (2003) 124:A80.
    • (2003) Gastroenterology , vol.124
    • Holtmann, G.1    Siffert, W.2    Grote, E.3
  • 72
    • 0034964914 scopus 로고    scopus 로고
    • Beneficial effects of converting liver transplant recipients from cyclosporine to tacrolimus on blood pressure, serum lipids, and weight
    • NEAL DA, GIMSON AE, GIBBS P, ALEXANDER GJ: Beneficial effects of converting liver transplant recipients from cyclosporine to tacrolimus on blood pressure, serum lipids, and weight. Liver Transpl. (2001) 7(6):533-539.
    • (2001) Liver Transpl. , vol.7 , Issue.6 , pp. 533-539
    • Neal, D.A.1    Gimson, A.E.2    Gibbs, P.3    Alexander, G.J.4
  • 73
    • 0032547341 scopus 로고    scopus 로고
    • Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4
    • REBBECK TR, JAFFE JM, WALKER AH, WEIN AJ, MALKOWICZ SB: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. J. Natl Cancer Inst. (1998) 90(16):1225-1229.
    • (1998) J. Natl Cancer Inst. , vol.90 , Issue.16 , pp. 1225-1229
    • Rebbeck, T.R.1    Jaffe, J.M.2    Walker, A.H.3    Wein, A.J.4    Malkowicz, S.B.5
  • 74
    • 0347359079 scopus 로고    scopus 로고
    • Increased transcriptional activity of the CYP3A4*1B promoter variant
    • AMIRIMANI B, NING B, DEITZ AC et al.: Increased transcriptional activity of the CYP3A4*1B promoter variant. Environ. Mol. Mutagen. (2003) 42(4):299-305.
    • (2003) Environ. Mol. Mutagen. , vol.42 , Issue.4 , pp. 299-305
    • Amirimani, B.1    Ning, B.2    Deitz, A.C.3
  • 75
    • 0041831261 scopus 로고    scopus 로고
    • Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacogenetics of the calcineurin inhibitors cyclosporine and tacrolimus
    • HESSELINK DA, VAN SCHAIK RH, VAN DER HEIDEN IP et al.: Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacogenetics of the calcineurin inhibitors cyclosporine and tacrolimus. Clin. Pharmacol. Ther. (2003) 74(3):245-254.
    • (2003) Clin. Pharmacol. Ther. , vol.74 , Issue.3 , pp. 245-254
    • Hesselink, D.A.1    van Schaik, R.H.2    van der Heiden, I.P.3
  • 76
    • 10044294681 scopus 로고    scopus 로고
    • Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes
    • HESSELINK DA, VAN GELDER T, VAN SCHAIK RH et al.: Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes. Clin. Pharmacol. Ther. (2004) 76(6):545-556.
    • (2004) Clin. Pharmacol. Ther. , vol.76 , Issue.6 , pp. 545-556
    • Hesselink, D.A.1    van Gelder, T.2    van Schaik, R.H.3
  • 77
    • 0035071598 scopus 로고    scopus 로고
    • Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
    • KUEHL P, ZHANG J, LIN Y et al.: Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. Nat. Genet. (2001) 27(4):383-391.
    • (2001) Nat. Genet. , vol.27 , Issue.4 , pp. 383-391
    • Kuehl, P.1    Zhang, J.2    Lin, Y.3
  • 78
    • 16244419058 scopus 로고    scopus 로고
    • Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus
    • ZHAO Y, SONG M, GUAM D et al.: Genetic polymorphisms of CYP3A5 genes and concentration of the cyclosporine and tacrolimus. Transplant. Proc. (2005) 37(1):178-181.
    • (2005) Transplant. Proc. , vol.37 , Issue.1 , pp. 178-181
    • Zhao, Y.1    Song, M.2    Guan, D.3
  • 79
    • 0023447098 scopus 로고
    • Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
    • THIEBAUT F, TSURUO T, HAMADA H et al.: Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. USA (1987) 84(21):7735-7738.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , Issue.21 , pp. 7735-7738
    • Thiebaut, F.1    Tsuruo, T.2    Hamada, H.3
  • 80
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
    • HOFFMEYER S, BURK O, VON RICHTER O et al.: Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo. Proc. Natl. Acad. Sci. USA (2000) 97(7):3473-3478.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.7 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3
  • 81
    • 3142734959 scopus 로고    scopus 로고
    • MDR-1 C3435T polymorphism influences cyclosporine a dose requirement in liver-transplant recipients
    • BONHOMME-FAIVRE L, DEVOCELLE A, SALIBA F et al.: MDR-1 C3435T polymorphism influences cyclosporine a dose requirement in liver-transplant recipients. Transplantation (2004) 78(1):21-25.
    • (2004) Transplantation , vol.78 , Issue.1 , pp. 21-25
    • Bonhomme-Faivre, L.1    Devocelle, A.2    Saliba, F.3
  • 82
    • 20344379217 scopus 로고    scopus 로고
    • Initial dosage adjustment for oral administration of tacrolimus using the intestinal MDR1 level in living-donor liver transplant recipients
    • MASUDA S, GOTO M, OKUDA M et al.: Initial dosage adjustment for oral administration of tacrolimus using the intestinal MDR1 level in living-donor liver transplant recipients. Transplant. Proc. (2005) 37(4):1728-1729.
    • (2005) Transplant. Proc. , vol.37 , Issue.4 , pp. 1728-1729
    • Masuda, S.1    Goto, M.2    Okuda, M.3
  • 83
    • 29244457552 scopus 로고    scopus 로고
    • Impact of multidrug resistance 1 gene polymorphism on tacrolimus dose and concentration-to-dose ratio in Chinese liver transplantation recipients
    • JIN J, WU LH, WANG WL et al.: Impact of multidrug resistance 1 gene polymorphism on tacrolimus dose and concentration-to-dose ratio in Chinese liver transplantation recipients. Zhonghua Yi Xue Yi Chuan Xue Za Zhi (2005) 22(6):616-620.
    • (2005) Zhonghua Yi Xue Yi Chuan Xue Za Zhi , vol.22 , Issue.6 , pp. 616-620
    • Jin, J.1    Wu, L.H.2    Wang, W.L.3
  • 84
    • 0037115210 scopus 로고    scopus 로고
    • Tacrolimus pharmacogenetics: Polymorphisms associated with expression of cytochrome P4503A5 and P-glycoprotein correlate with dose requirement
    • MACPHEE IA, FREDERICKS S, TAI T et al.: Tacrolimus pharmacogenetics: polymorphisms associated with expression of cytochrome P4503A5 and P-glycoprotein correlate with dose requirement. Transplantation (2002) 74(11):1486-1489.
    • (2002) Transplantation , vol.74 , Issue.11 , pp. 1486-1489
    • Macphee, I.A.1    Fredericks, S.2    Tai, T.3
  • 85
    • 0037693831 scopus 로고    scopus 로고
    • Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms
    • ZHENG H, WEBBER S, ZEEVI A et al.: Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms. Am. J. Transplant. (2003) 3(4):477-483.
    • (2003) Am. J. Transplant. , vol.3 , Issue.4 , pp. 477-483
    • Zheng, H.1    Webber, S.2    Zeevi, A.3
  • 86
    • 0038304548 scopus 로고    scopus 로고
    • Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients
    • ANGLICHEAU D, VERSTUYFT C, LAURENT-PUIG P et al.: Association of the multidrug resistance-1 gene single-nucleotide polymorphisms with the tacrolimus dose requirements in renal transplant recipients. J. Am. Soc. Nephrol. (2003) 14(7):1889-1896.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , Issue.7 , pp. 1889-1896
    • Anglicheau, D.1    Verstuyft, C.2    Laurent-Puig, P.3
  • 88
    • 0036817470 scopus 로고    scopus 로고
    • Epidemiology and prevention of colorectal cancer
    • HAWK ET, LIMBURG PJ, VINER JL: Epidemiology and prevention of colorectal cancer. Surg. Clin. North Am. (2002) 82(5):905-941.
    • (2002) Surg. Clin. North Am. , vol.82 , Issue.5 , pp. 905-941
    • Hawk, E.T.1    Limburg, P.J.2    Viner, J.L.3
  • 89
    • 0034734896 scopus 로고    scopus 로고
    • ABC of colorectal cancer: Epidemiology
    • BOYLE P, LANGMAN JS: ABC of colorectal cancer: epidemiology. Br. Med. J. (2000) 321(7264):805-808.
    • (2000) Br. Med. J. , vol.321 , Issue.7264 , pp. 805-808
    • Boyle, P.1    Langman, J.S.2
  • 90
    • 0032847412 scopus 로고    scopus 로고
    • Adjuvant therapy of colon cancer
    • MOORE HC, HALLER DG: Adjuvant therapy of colon cancer. Semin. Oncol. (1999) 26(5):545-555.
    • (1999) Semin. Oncol. , vol.26 , Issue.5 , pp. 545-555
    • Moore, H.C.1    Haller, D.G.2
  • 91
    • 0031878308 scopus 로고    scopus 로고
    • Update on adjuvant treatment of colorectal cancer
    • STEWART JM, ZALCBERG JR: Update on adjuvant treatment of colorectal cancer. Curr. Opin. Oncol. (1998) 10(4):367-374.
    • (1998) Curr. Opin. Oncol. , vol.10 , Issue.4 , pp. 367-374
    • Stewart, J.M.1    Zalcberg, J.R.2
  • 92
    • 0034596549 scopus 로고    scopus 로고
    • Palliative chemotherapy for advanced colorectal cancer: Systematic review and meta-analysis
    • Colorectal Cancer Collaborative Group
    • SIMMONDS PC: Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis. Colorectal Cancer Collaborative Group. Br. Med. J. (2000) 321(7260):531-535.
    • (2000) Br. Med. J. , vol.321 , Issue.7260 , pp. 531-535
    • Simmonds, P.C.1
  • 93
    • 0034048729 scopus 로고    scopus 로고
    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    • SALONGA D, DANENBERG KD, JOHNSON M et al.: Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin. Cancer Res. (2000) 6(4):1322-1327.
    • (2000) Clin. Cancer Res. , vol.6 , Issue.4 , pp. 1322-1327
    • Salonga, D.1    Danenberg, K.D.2    Johnson, M.3
  • 94
    • 0000163968 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity
    • MILANO G, ETIENNE MC, PIERREFITE V et al.: Dihydropyrimidine dehydrogenase deficiency and fluorouracil-related toxicity. Br. J. Cancer (1999) 79(3-4):627-630.
    • (1999) Br. J. Cancer , vol.79 , Issue.3-4 , pp. 627-630
    • Milano, G.1    Etienne, M.C.2    Pierrefite, V.3
  • 95
    • 0029973215 scopus 로고    scopus 로고
    • Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity
    • WEI X, MCLEOD HL, MCMURROUGH J, GONZALEZ FJ, FERNANDEZ-SALGUERO P: Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity. J. Clin. Invest. (1996) 98(3):610-615.
    • (1996) J. Clin. Invest. , vol.98 , Issue.3 , pp. 610-615
    • Wei, X.1    McLeod, H.L.2    McMurrough, J.3    Gonzalez, F.J.4    Fernandez-Salguero, P.5
  • 96
    • 7344249042 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects
    • RIDGE SA, SLUDDEN J, BROWN O et al.: Dihydropyrimidine dehydrogenase pharmacogenetics in Caucasian subjects. Br. J. Clin. Pharmacol. (1998) 46(2):151-156.
    • (1998) Br. J. Clin. Pharmacol. , vol.46 , Issue.2 , pp. 151-156
    • Ridge, S.A.1    Sludden, J.2    Brown, O.3
  • 97
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • HORIE N, AIBA H, OGURO K, HOJO H, TAKEISHI K: Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct. Funct. (1995) 20(3):191-197.
    • (1995) Cell Struct. Funct. , vol.20 , Issue.3 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3    Hojo, H.4    Takeishi, K.5
  • 98
    • 0033427561 scopus 로고    scopus 로고
    • Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
    • KAWAKAMI K, OMURA K, KANEHIRA E, WATANABE Y: Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anti-Cancer Res. (1999) 19(4B):3249-3252.
    • (1999) Anti-Cancer Res. , vol.19 B , Issue.4 , pp. 3249-3252
    • Kawakami, K.1    Omura, K.2    Kanehira, E.3    Watanabe, Y.4
  • 99
    • 1442290323 scopus 로고    scopus 로고
    • Thymidylate synthase expression and prognosis in colorectal cancer: A systematic review and meta-analysis
    • POPAT S, MATAKIDOU A, HOULSTON RS: Thymidylate synthase expression and prognosis in colorectal cancer: a systematic review and meta-analysis: J. Clin. Oncol. (2004) 22(3):529-536.
    • (2004) J. Clin. Oncol. , vol.22 , Issue.3 , pp. 529-536
    • Popat, S.1    Matakidou, A.2    Houlston, R.S.3
  • 100
    • 0034671387 scopus 로고    scopus 로고
    • Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
    • ANDO Y, SAKA H, ANDO M et al.: Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res. (2000) 60(24):6921-6926.
    • (2000) Cancer Res. , vol.60 , Issue.24 , pp. 6921-6926
    • Ando, Y.1    Saka, H.2    Ando, M.3
  • 101
    • 0036025450 scopus 로고    scopus 로고
    • UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity
    • IYER L, DAS S, JANISCH L et al.: UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. Pharmacogenomics J. (2002) 2(1):43-47.
    • (2002) Pharmacogenomics J. , vol.2 , Issue.1 , pp. 43-47
    • Iyer, L.1    Das, S.2    Janisch, L.3
  • 102
    • 33744804311 scopus 로고    scopus 로고
    • Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin
    • HAN JY, LIM HS, SHIN ES et al.: Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin. J. Clin. Oncol. (2006) 24(15):2237-2244.
    • (2006) J. Clin. Oncol. , vol.24 , Issue.15 , pp. 2237-2244
    • Han, J.Y.1    Lim, H.S.2    Shin, E.S.3
  • 104
    • 0035174375 scopus 로고    scopus 로고
    • A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer
    • STOEHLMACHER J, GHADERI V, IOBAL S et al.: A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. Anti-Cancer Res. (2001) 21(4B):3075-3079.
    • (2001) Anti-Cancer Res. , vol.21 B , Issue.4 , pp. 3075-3079
    • Stoehlmacher, J.1    Ghaderi, V.2    Iobal, S.3
  • 105
    • 0035893755 scopus 로고    scopus 로고
    • A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer
    • PARK DJ, STOEHLMACHER J, ZHANG W et al.: A Xeroderma pigmentosum group D gene polymorphism predicts clinical outcome to platinum-based chemotherapy in patients with advanced colorectal cancer. Cancer Res. (2001) 61(24):8654-8658.
    • (2001) Cancer Res. , vol.61 , Issue.24 , pp. 8654-8658
    • Park, D.J.1    Stoehlmacher, J.2    Zhang, W.3
  • 106
    • 0037134707 scopus 로고    scopus 로고
    • Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
    • STOEHLMACHER J, PARK DJ, ZHANG W et al.: Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer. J. Natl Cancer Inst. (2002) 94(12):936-942.
    • (2002) J. Natl Cancer Inst. , vol.94 , Issue.12 , pp. 936-942
    • Stoehlmacher, J.1    Park, D.J.2    Zhang, W.3


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