Tacrolimus (FK506) attenuates biphasic cytochrome c release and Bad phosphorylation following transient cerebral ischemia in mice

Neuroscience

Volumn 142, Issue 3, 2006, Pages 789-797

  Li, J Y ^a   Furuichi, Y ^a   Matsuoka, N ^a   Mutoh, S ^a   Yanagihara, T ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b Osaka Neurological Research Institute   (Japan)

Author keywords

apoptosis; cytochrome c; middle cerebral artery occlusion; neuroprotection; reperfusion; tacrolimus (FK506)

Indexed keywords

CASPASE 3; CYTOCHROME C; DNA FRAGMENT; PROTEIN BAD; SERINE; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; CYTOSOL; DEATH; ENZYME ACTIVATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MITOCHONDRION; MOUSE; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REPERFUSION; SURVIVAL; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; BCL-ASSOCIATED DEATH PROTEIN; BLOTTING, WESTERN; BRAIN INFARCTION; CYTOCHROMES C; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; IN SITU NICK-END LABELING; ISCHEMIC ATTACK, TRANSIENT; MALE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; TACROLIMUS; TIME FACTORS;

EID: 33749254605     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.06.064     Document Type: Article

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