-
1
-
-
0037363599
-
Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides
-
Agostinho P., Oliveira C.R. Involvement of calcineurin in the neurotoxic effects induced by amyloid-beta and prion peptides. Eur. J. Neurosci. 17:2003;1189-1196
-
(2003)
Eur. J. Neurosci.
, vol.17
, pp. 1189-1196
-
-
Agostinho, P.1
Oliveira, C.R.2
-
2
-
-
0028793257
-
Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function
-
Ankarcrona M., Dypbukt J.M., Bonfoco E., Zhivotovsky B., Orrenius S., Lipton S.A., Nicotea P. Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron. 15:1995;961-973
-
(1995)
Neuron
, vol.15
, pp. 961-973
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Bonfoco, E.3
Zhivotovsky, B.4
Orrenius, S.5
Lipton, S.A.6
Nicotea, P.7
-
3
-
-
0030574021
-
Calcineurin and mitochondrial function in glutamate-induced neuronal cell death
-
Ankarcrona M., Dypbukt J.M., Orrenius S., Nicotea P. Calcineurin and mitochondrial function in glutamate-induced neuronal cell death. FEBS Lett. 394:1996;321-324
-
(1996)
FEBS Lett.
, vol.394
, pp. 321-324
-
-
Ankarcrona, M.1
Dypbukt, J.M.2
Orrenius, S.3
Nicotea, P.4
-
4
-
-
0033019790
-
Caicineurin inhibitor FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury
-
Bochelen D., Rudin M., Sauter A. Caicineurin inhibitor FK506 and SDZ ASM 981 alleviate the outcome of focal cerebral ischemic/reperfusion injury. J. Pharmacol. Exp. Ther. 288:1999;653-659
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.288
, pp. 653-659
-
-
Bochelen, D.1
Rudin, M.2
Sauter, A.3
-
5
-
-
0030850505
-
Neuroprotective action of FK506 in experimental stroke: In vivo evidence against an antiexcitotoxic mechanism
-
Butcher S.P., Henshall D.C., Tamura Y., Iwasaki K., Sharkey J. Neuroprotective action of FK506 in experimental stroke: in vivo evidence against an antiexcitotoxic mechanism. J. Neurosci. 17:1997;6939-6946
-
(1997)
J. Neurosci.
, vol.17
, pp. 6939-6946
-
-
Butcher, S.P.1
Henshall, D.C.2
Tamura, Y.3
Iwasaki, K.4
Sharkey, J.5
-
6
-
-
0030053303
-
Apoptosis and necrosis after reversible focal ischemia: An in situ DNA fragmentation analysis
-
Charriaut-Marlangue C., Margaill I., Represa A., Popovici T., Plotkine M., Ben-Ari Y. Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis. J. Cereb. Blood Flow Metab. 16:1996;186-194
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 186-194
-
-
Charriaut-Marlangue, C.1
Margaill, I.2
Represa, A.3
Popovici, T.4
Plotkine, M.5
Ben-Ari, Y.6
-
7
-
-
0030047274
-
Very delayed infarction after mild focal cerebral ischemia: A role for apoptosis?
-
Du C., Hu R., Casernansky C.A., Hsu C.Y., Choi D.W. Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis? J. Cereb. Blood Flow Metab. 16:1996;195-201
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 195-201
-
-
Du, C.1
Hu, R.2
Casernansky, C.A.3
Hsu, C.Y.4
Choi, D.W.5
-
8
-
-
0034996767
-
Early and delayed neuroprotective effects of FK506 on experimental focal ischemia quantitatively assessed by diffusion-weighted MRI
-
Ebisu T., Katsuta K., Fujikawa A., Aoki I., Umeda M., Naruse S., Tanaka C. Early and delayed neuroprotective effects of FK506 on experimental focal ischemia quantitatively assessed by diffusion-weighted MRI. Magn. Reson. Imaging. 19:2001;153-160
-
(2001)
Magn. Reson. Imaging
, vol.19
, pp. 153-160
-
-
Ebisu, T.1
Katsuta, K.2
Fujikawa, A.3
Aoki, I.4
Umeda, M.5
Naruse, S.6
Tanaka, C.7
-
10
-
-
0031737635
-
Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats
-
Fujimura M., Morita-Fujimura Y., Murakami K., Kawase M., Chan P.H. Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 18:1998;1239-1247
-
(1998)
J. Cereb. Blood Flow Metab.
, vol.18
, pp. 1239-1247
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Murakami, K.3
Kawase, M.4
Chan, P.H.5
-
11
-
-
0033135367
-
Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice
-
Fujimura M., Morita-Fujimura Y., Kawase M., Copin J.-C., Calagui B., Epstein C.J., Chan P.H. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J. Neurosci. 19:1999;3414-3422
-
(1999)
J. Neurosci.
, vol.19
, pp. 3414-3422
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Kawase, M.3
Copin, J.-C.4
Calagui, B.5
Epstein, C.J.6
Chan, P.H.7
-
12
-
-
0037424434
-
Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: Dose dependency, therapeutic time window and long-term efficacy
-
Furuichi Y., Katsuta K., Maeda M., Ueyama N., Moriguchi A., Matsuoka N., Goto T., Yanagihara T. Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: dose dependency, therapeutic time window and long-term efficacy. Brain Res. 965:2003;137-145
-
(2003)
Brain Res.
, vol.965
, pp. 137-145
-
-
Furuichi, Y.1
Katsuta, K.2
Maeda, M.3
Ueyama, N.4
Moriguchi, A.5
Matsuoka, N.6
Goto, T.7
Yanagihara, T.8
-
13
-
-
0026648674
-
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
-
Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501
-
(1992)
J. Cell Biol.
, vol.119
, pp. 493-501
-
-
Gavrieli, Y.1
Sherman, Y.2
Ben-Sasson, S.A.3
-
14
-
-
0032723945
-
Glutathione depletion cause cytochrome c release even in the absence of cell commitment to apoptosis
-
Ghibelli L., Coppola S., Fanelli C., Rotilio G., Civitareale P., Scovassi A.I., Ciriolo M.R. Glutathione depletion cause cytochrome c release even in the absence of cell commitment to apoptosis. FASEB J. 13:1999;2031-2036
-
(1999)
FASEB J.
, vol.13
, pp. 2031-2036
-
-
Ghibelli, L.1
Coppola, S.2
Fanelli, C.3
Rotilio, G.4
Civitareale, P.5
Scovassi, A.I.6
Ciriolo, M.R.7
-
15
-
-
0032575752
-
Mitochondria and apoptosis
-
Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312
-
(1998)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
16
-
-
0033951842
-
Early and sequential recruitment of apoptotic effectors after focal permanent ischemia in mice
-
Guégan C., Sola B. Early and sequential recruitment of apoptotic effectors after focal permanent ischemia in mice. Brain Res. 856:2000;93-100
-
(2000)
Brain Res.
, vol.856
, pp. 93-100
-
-
Guégan, C.1
Sola, B.2
-
17
-
-
85047697158
-
Release of intact, monomeric cytochrome c from apoptotic and necrotic cells
-
Jemmerson R., LaPlante B., Treeful A. Release of intact, monomeric cytochrome c from apoptotic and necrotic cells. Cell Death Differ. 9:2002;538-548
-
(2002)
Cell Death Differ.
, vol.9
, pp. 538-548
-
-
Jemmerson, R.1
Laplante, B.2
Treeful, A.3
-
18
-
-
0032574761
-
Bax directly induces release of cytochrome c from isolated mitochondria
-
Jurgensmeier J.M., Deveraux Q., Ellerby L., Bredeson D., Reed J.C. Bax directly induces release of cytochrome c from isolated mitochondria. Proc. Natl. Acad. Sci. U. S. A. 95:1998;4997-5002
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 4997-5002
-
-
Jurgensmeier, J.M.1
Deveraux, Q.2
Ellerby, L.3
Bredeson, D.4
Reed, J.C.5
-
19
-
-
0035946989
-
FK506, but not cyclospolin A, prevents mitochondrial dysfunction during hypoxia in rat hepatocytes
-
Kaibori M., Inoue T., Tu W., Oda M., Kwon A.-H., Kamiyama Y., Okumura T. FK506, but not cyclospolin A, prevents mitochondrial dysfunction during hypoxia in rat hepatocytes. Life Sci. 69:2001;17-26
-
(2001)
Life Sci.
, vol.69
, pp. 17-26
-
-
Kaibori, M.1
Inoue, T.2
Tu, W.3
Oda, M.4
Kwon, A.-H.5
Kamiyama, Y.6
Okumura, T.7
-
20
-
-
0028836150
-
The neuroprotective effect of the novel noncompetitive NMDA antagonist, FR11527 in focal cerebral ischemia in rats
-
Katsuta K., Nakanishi H., Shirakawa K., Yoshida K., Takagi K., Tamura A. The neuroprotective effect of the novel noncompetitive NMDA antagonist, FR11527 in focal cerebral ischemia in rats. J. Cereb. Blood Flow Metab. 15:1995;345-348
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 345-348
-
-
Katsuta, K.1
Nakanishi, H.2
Shirakawa, K.3
Yoshida, K.4
Takagi, K.5
Tamura, A.6
-
21
-
-
0037352890
-
The immunophilin-ligands FK506 and V-10,367 mediate neuroprotection by the heat shock response
-
Klettner A., Herdegen T. The immunophilin-ligands FK506 and V-10,367 mediate neuroprotection by the heat shock response. Br. J. Pharmacol. 138:2003;1004-1012
-
(2003)
Br. J. Pharmacol.
, vol.138
, pp. 1004-1012
-
-
Klettner, A.1
Herdegen, T.2
-
22
-
-
0028905230
-
Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat
-
Li Y., Chopp M., Jiang N., Yao F., Zaloga C. Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J. Cereb. Blood Flow Metab. 15:1995;389-397
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 389-397
-
-
Li, Y.1
Chopp, M.2
Jiang, N.3
Yao, F.4
Zaloga, C.5
-
23
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhardia D., Budihardia I., Srinvasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhardia, D.2
Budihardia, I.3
Srinvasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
24
-
-
0027501851
-
Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
-
Linnik M.D., Zobrist R.H., Hatfield M.D. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke. 24:1993;2002-2008
-
(1993)
Stroke
, vol.24
, pp. 2002-2008
-
-
Linnik, M.D.1
Zobrist, R.H.2
Hatfield, M.D.3
-
25
-
-
0032845121
-
Ischemic cell death in brain neurons
-
Lipton P. Ischemic cell death In brain neurons. Physiol. Rev. 79:1999;1431-1539
-
(1999)
Physiol. Rev.
, vol.79
, pp. 1431-1539
-
-
Lipton, P.1
-
26
-
-
0025893168
-
Calcineurin is a common target of cyclophilin-cyclosporin a and FKBP-FK506 complexes
-
Liu J., Farmer J.D., Lane W.S., Friedman J., Weissman I., Schreiber S.L. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell. 166:1991;807-815
-
(1991)
Cell
, vol.166
, pp. 807-815
-
-
Liu, J.1
Farmer, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
27
-
-
0032555215
-
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis
-
Liu X., Li P., Widlak P., Zou H., Luo X., Garrard W.T., Wang X. The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis. Proc. Natl. Acad. Sci. U. S. A. 95:1998;8461-8466
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 8461-8466
-
-
Liu, X.1
Li, P.2
Widlak, P.3
Zou, H.4
Luo, X.5
Garrard, W.T.6
Wang, X.7
-
28
-
-
0034254932
-
Delayed mitochondrial dysfunction in excitotoxic neuron death: Cytochrome c release and a secondary increase in superoxide production
-
Luetjens C.M., Bui N.T., Sengpiel B., Munstermann G., Poppe M., Krohn A.J., Bauerbach E., Krieglstein J., Prehn J.H.M. Delayed mitochondrial dysfunction in excitotoxic neuron death: cytochrome c release and a secondary increase in superoxide production. J. Neurosci. 20:2000;5715-5723
-
(2000)
J. Neurosci.
, vol.20
, pp. 5715-5723
-
-
Luetjens, C.M.1
Bui, N.T.2
Sengpiel, B.3
Munstermann, G.4
Poppe, M.5
Krohn, A.J.6
Bauerbach, E.7
Krieglstein, J.8
Prehn, J.H.M.9
-
29
-
-
0036791876
-
A combined treatment with tacrolimus (FK506) and recombinant tissue plasminogen activator for thrombotic focal cerebral ischemia in rats: Increased neuroprotective efficacy and extended therapeutic time window
-
Maeda M., Furuichi Y., Ueyama N., Moriguchi A., Sato N., Matsuoka N., Goto T., Yanagihara T. A combined treatment with tacrolimus (FK506) and recombinant tissue plasminogen activator for thrombotic focal cerebral ischemia in rats: increased neuroprotective efficacy and extended therapeutic time window. J. Cereb. Blood Flow Metab. 22:2002;1205-1211
-
(2002)
J. Cereb. Blood Flow Metab.
, vol.22
, pp. 1205-1211
-
-
Maeda, M.1
Furuichi, Y.2
Ueyama, N.3
Moriguchi, A.4
Sato, N.5
Matsuoka, N.6
Goto, T.7
Yanagihara, T.8
-
30
-
-
0032941253
-
Potential role of calcineurin for brain ischemia and traumatic injury
-
Morioka M., Hamada J.H., Ushio Y., Miyamoto E. Potential role of calcineurin for brain ischemia and traumatic injury. Prog. Neurobiol. 58:1998;1-30
-
(1998)
Prog. Neurobiol.
, vol.58
, pp. 1-30
-
-
Morioka, M.1
Hamada, J.H.2
Ushio, Y.3
Miyamoto, E.4
-
31
-
-
0033830374
-
The chaperone function of hsp70 is required for protection against stress-induced apoptosis
-
Mosser D.D., Caron A.W., Bourget L., Meriin A.B., Sherman M.Y., Morimoto R.I., Massie B. The chaperone function of hsp70 is required for protection against stress-induced apoptosis. Mol. Cell. Biol. 20:2000;7146-7159
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 7146-7159
-
-
Mosser, D.D.1
Caron, A.W.2
Bourget, L.3
Meriin, A.B.4
Sherman, M.Y.5
Morimoto, R.I.6
Massie, B.7
-
32
-
-
17444373424
-
Cytochrome c is released from mitochondria into the cytosol after cerebral anoxia or ischemia
-
Pérez-Pinzón M.A., Xu G.P., Born J., Lorenzo J., Busto R., Rosenthal M., Sick T.J. Cytochrome c is released from mitochondria into the cytosol after cerebral anoxia or ischemia. J. Cereb. Blood Flow Metab. 19:1999;39-43
-
(1999)
J. Cereb. Blood Flow Metab.
, vol.19
, pp. 39-43
-
-
Pérez-Pinzón, M.A.1
Xu, G.P.2
Born, J.3
Lorenzo, J.4
Busto, R.5
Rosenthal, M.6
Sick, T.J.7
-
33
-
-
0034069630
-
Temporal profile of cytochrome c and caspase-3 immunoreactivities and TUNEL staining after permanent middle cerebral artery occlusion in rats
-
Sasaki C., Kitagawa H., Zhang W.R., Warita H., Sakai K., Abe K. Temporal profile of cytochrome c and caspase-3 immunoreactivities and TUNEL staining after permanent middle cerebral artery occlusion in rats. Neurol. Res. 22:2000;223-228
-
(2000)
Neurol. Res.
, vol.22
, pp. 223-228
-
-
Sasaki, C.1
Kitagawa, H.2
Zhang, W.R.3
Warita, H.4
Sakai, K.5
Abe, K.6
-
34
-
-
0027937489
-
Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia
-
Sharkey J., Butcher S.P. Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia. Nature. 371:1994;336-339
-
(1994)
Nature
, vol.371
, pp. 336-339
-
-
Sharkey, J.1
Butcher, S.P.2
-
35
-
-
0028971035
-
2+-activated cell death in mammalian cells
-
2+- activated cell death in mammalian cells. J. Cell Biol. 131:1995;735-743
-
(1995)
J. Cell Biol.
, vol.131
, pp. 735-743
-
-
Shibasaki, F.1
McKeon, F.2
-
36
-
-
0035662825
-
FK506 attenuates early ischemic neuronal death in a monkey model of stroke
-
Takamatsu H., Tsukada H., Noda A., Kakiuchi T., Nishiyama S., Nishimura S., Umemura K. FK506 attenuates early ischemic neuronal death in a monkey model of stroke. J. Nucl. Med. 42:2001;1833-1840
-
(2001)
J. Nucl. Med.
, vol.42
, pp. 1833-1840
-
-
Takamatsu, H.1
Tsukada, H.2
Noda, A.3
Kakiuchi, T.4
Nishiyama, S.5
Nishimura, S.6
Umemura, K.7
-
37
-
-
0019868418
-
Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion
-
Tamura A., Graham D.I., McCulloch J., Teasdale G.M. Focal cerebral ischaemia in the rat: 1. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 1:1981;53-60
-
(1981)
J. Cereb. Blood Flow Metab.
, vol.1
, pp. 53-60
-
-
Tamura, A.1
Graham, D.I.2
McCulloch, J.3
Teasdale, G.M.4
-
38
-
-
0035910371
-
2-induced cell damage by increasing glutathione levels in NG108-15 cells
-
2-induced cell damage by increasing glutathione levels in NG108-15 cells. Brain Res. 889:2001;225-228
-
(2001)
Brain Res.
, vol.889
, pp. 225-228
-
-
Tanaka, K.1
Fujita, N.2
Yoshioka, M.3
Ogawa, N.4
-
39
-
-
0037087049
-
GPI1046 prevents dopaminergic dysfunction by activating glutathione system in the mouse striatum
-
Tanaka K., Yoshioka M., Miyazaki I., Fujita N., Ogawa N. GPI1046 prevents dopaminergic dysfunction by activating glutathione system in the mouse striatum. Neurosci. Lett. 321:2002;45-48
-
(2002)
Neurosci. Lett.
, vol.321
, pp. 45-48
-
-
Tanaka, K.1
Yoshioka, M.2
Miyazaki, I.3
Fujita, N.4
Ogawa, N.5
-
40
-
-
0034605121
-
Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release
-
von Ahsen O., Renken C., Perkins G., Kluck R.M., Bossy-Wetzel E., Newmeyer D.D. Preservation of mitochondrial structure and function after Bid- or Bax-mediated cytochrome c release. J. Cell Biol. 150:2000;1027-1036
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1027-1036
-
-
Von Ahsen, O.1
Renken, C.2
Perkins, G.3
Kluck, R.M.4
Bossy-Wetzel, E.5
Newmeyer, D.D.6
-
41
-
-
0033537768
-
2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science. 284:1999;339-343
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.-G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
42
-
-
0030569031
-
Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils
-
Yagita Y., Kitagawa K., Matsushita K., Taguchi A., Mabuchi T., Ohtsuki T., Yanagihara T., Matsumoto M. Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils. Life Sci. 59:1996;1643-1650
-
(1996)
Life Sci.
, vol.59
, pp. 1643-1650
-
-
Yagita, Y.1
Kitagawa, K.2
Matsushita, K.3
Taguchi, A.4
Mabuchi, T.5
Ohtsuki, T.6
Yanagihara, T.7
Matsumoto, M.8
-
43
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
-
Yang E., Zha J., Jockel J., Boise L.H., Thompson C.B., Korsmeyer S.J. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell. 80:1995;285-291
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
|