Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice

Stroke

Volumn 32, Issue 8, 2001, Pages 1906-1911

  Namura, Shobu ^a   Nagata, Izumi ^a   Takami, Shinya ^a   Masayasu, Hiroyuki ^b   Kikuchi, Haruhiko ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b DAIICHI SANKYO CO   (Japan)

Author keywords

Apoptosis; Cerebral ischemia, focal; Mice; Neuroprotection; Oxidative stress

Indexed keywords

CYTOCHROME C; DNA FRAGMENT; EBSELEN; HALOTHANE; ORGANOSELENIUM DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN MITOCHONDRION; CELL NUCLEUS; CONTROLLED STUDY; ENZYME RELEASE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NISSL STAINING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; STROKE; TRANSIENT ISCHEMIC ATTACK; WESTERN BLOTTING;

EID: 0034884323     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.STR.32.8.1906     Document Type: Article

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