-
1
-
-
15944398014
-
A molecular and genetic arsenal for systems neuroscience
-
Callaway E.M. A molecular and genetic arsenal for systems neuroscience. Trends Neurosci 28 (2005) 196-201
-
(2005)
Trends Neurosci
, vol.28
, pp. 196-201
-
-
Callaway, E.M.1
-
2
-
-
0030610646
-
Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin
-
Miyawaki A., Llopis J., Heim R., McCaffery J.M., Adams J.A., Ikura M., and Tsien R.Y. Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature 388 (1997) 882-887
-
(1997)
Nature
, vol.388
, pp. 882-887
-
-
Miyawaki, A.1
Llopis, J.2
Heim, R.3
McCaffery, J.M.4
Adams, J.A.5
Ikura, M.6
Tsien, R.Y.7
-
4
-
-
33646145526
-
A FRET-based calcium biosensor with fast signal kinetics and high fluorescence change
-
Mank M., Reiff D.F., Heim N., Friedrich M.W., Borst A., and Griesbeck O. A FRET-based calcium biosensor with fast signal kinetics and high fluorescence change. Biophys J 90 (2006) 1790-1796
-
(2006)
Biophys J
, vol.90
, pp. 1790-1796
-
-
Mank, M.1
Reiff, D.F.2
Heim, N.3
Friedrich, M.W.4
Borst, A.5
Griesbeck, O.6
-
5
-
-
20844449080
-
Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors
-
Okumoto S., Looger L.L., Micheva K.D., Reimer R.J., Smith S.J., and Frommer W.B. Detection of glutamate release from neurons by genetically encoded surface-displayed FRET nanosensors. Proc Natl Acad Sci USA 102 (2005) 8740-8745
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8740-8745
-
-
Okumoto, S.1
Looger, L.L.2
Micheva, K.D.3
Reimer, R.J.4
Smith, S.J.5
Frommer, W.B.6
-
6
-
-
24344451972
-
Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering
-
Deuschle K., Okumoto S., Fehr M., Looger L.L., Kozhukh L., and Frommer W.B. Construction and optimization of a family of genetically encoded metabolite sensors by semirational protein engineering. Protein Sci 14 (2005) 2304-2314
-
(2005)
Protein Sci
, vol.14
, pp. 2304-2314
-
-
Deuschle, K.1
Okumoto, S.2
Fehr, M.3
Looger, L.L.4
Kozhukh, L.5
Frommer, W.B.6
-
7
-
-
0032500053
-
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
-
Miesenbock G., De Angelis D.A., and Rothman J.E. Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins. Nature 394 (1998) 192-195
-
(1998)
Nature
, vol.394
, pp. 192-195
-
-
Miesenbock, G.1
De Angelis, D.A.2
Rothman, J.E.3
-
8
-
-
0036221893
-
A genetically targetable fluorescent probe of channel gating with rapid kinetics
-
Ataka K., and Pieribone V.A. A genetically targetable fluorescent probe of channel gating with rapid kinetics. Biophys J 82 (2002) 509-516
-
(2002)
Biophys J
, vol.82
, pp. 509-516
-
-
Ataka, K.1
Pieribone, V.A.2
-
9
-
-
27644592613
-
A hybrid approach to measuring electrical activity in genetically specified neurons
-
To improve in vivo voltage detection, a hybrid approach is used by the authors to impart the speed of a dye with the specificity of a genetically encoded protein. More than most, this paper shows what can be achieved with well-known reagents used in an innovative way to solve a common problem.
-
Chanda B., Blunck R., Faria L.C., Schweizer F.E., Mody I., and Bezanilla F. A hybrid approach to measuring electrical activity in genetically specified neurons. Nat Neurosci 8 (2005) 1619-1626. To improve in vivo voltage detection, a hybrid approach is used by the authors to impart the speed of a dye with the specificity of a genetically encoded protein. More than most, this paper shows what can be achieved with well-known reagents used in an innovative way to solve a common problem.
-
(2005)
Nat Neurosci
, vol.8
, pp. 1619-1626
-
-
Chanda, B.1
Blunck, R.2
Faria, L.C.3
Schweizer, F.E.4
Mody, I.5
Bezanilla, F.6
-
10
-
-
0034912282
-
Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein
-
Sakai R., Repunte-Canonigo V., Raj C.D., and Knopfel T. Design and characterization of a DNA-encoded, voltage-sensitive fluorescent protein. Eur J Neurosci 13 (2001) 2314-2318
-
(2001)
Eur J Neurosci
, vol.13
, pp. 2314-2318
-
-
Sakai, R.1
Repunte-Canonigo, V.2
Raj, C.D.3
Knopfel, T.4
-
11
-
-
0030834492
-
A genetically encoded optical probe of membrane voltage
-
Siegel M.S., and Isacoff E.Y. A genetically encoded optical probe of membrane voltage. Neuron 19 (1997) 735-741
-
(1997)
Neuron
, vol.19
, pp. 735-741
-
-
Siegel, M.S.1
Isacoff, E.Y.2
-
12
-
-
17044387716
-
Local protein synthesis by BDNF is potentiated in hippocampal neurons exposed to ephrins
-
Miyata S., Mori Y., Fujiwara T., Ikenaka K., Matsuzaki S., Oono K., Katayama T., and Tohyama M. Local protein synthesis by BDNF is potentiated in hippocampal neurons exposed to ephrins. Brain Res Mol Brain Res 134 (2005) 333-337
-
(2005)
Brain Res Mol Brain Res
, vol.134
, pp. 333-337
-
-
Miyata, S.1
Mori, Y.2
Fujiwara, T.3
Ikenaka, K.4
Matsuzaki, S.5
Oono, K.6
Katayama, T.7
Tohyama, M.8
-
13
-
-
14644442259
-
Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons
-
The authors used both a GFP translation reporter and a localized application of a fluorescent puromycin analog to visualize localized protein synthesis in response to a dopamine agonist. This synthesis is dependent on protein kinase A signaling and can affect the levels of an AMPA receptor subunit, and is one of the first comprehensive observations of local protein synthesis in neuronal processes.
-
Smith W.B., Starck S.R., Roberts R.W., and Schuman E.M. Dopaminergic stimulation of local protein synthesis enhances surface expression of GluR1 and synaptic transmission in hippocampal neurons. Neuron 45 (2005) 765-779. The authors used both a GFP translation reporter and a localized application of a fluorescent puromycin analog to visualize localized protein synthesis in response to a dopamine agonist. This synthesis is dependent on protein kinase A signaling and can affect the levels of an AMPA receptor subunit, and is one of the first comprehensive observations of local protein synthesis in neuronal processes.
-
(2005)
Neuron
, vol.45
, pp. 765-779
-
-
Smith, W.B.1
Starck, S.R.2
Roberts, R.W.3
Schuman, E.M.4
-
14
-
-
3342935872
-
A general approach to detect protein expression in vivo using fluorescent puromycin conjugates
-
Starck S.R., Green H.M., Alberola-Ila J., and Roberts R.W. A general approach to detect protein expression in vivo using fluorescent puromycin conjugates. Chem Biol 11 (2004) 999-1008
-
(2004)
Chem Biol
, vol.11
, pp. 999-1008
-
-
Starck, S.R.1
Green, H.M.2
Alberola-Ila, J.3
Roberts, R.W.4
-
15
-
-
0034990497
-
Dynamic visualization of local protein synthesis in hippocampal neurons
-
Aakalu G., Smith W.B., Nguyen N., Jiang C., and Schuman E.M. Dynamic visualization of local protein synthesis in hippocampal neurons. Neuron 30 (2001) 489-502
-
(2001)
Neuron
, vol.30
, pp. 489-502
-
-
Aakalu, G.1
Smith, W.B.2
Nguyen, N.3
Jiang, C.4
Schuman, E.M.5
-
16
-
-
18644370150
-
In vivo performance of genetically encoded indicators of neural activity in flies
-
Reiff D.F., Ihring A., Guerrero G., Isacoff E.Y., Joesch M., Nakai J., and Borst A. In vivo performance of genetically encoded indicators of neural activity in flies. J Neurosci 25 (2005) 4766-4778
-
(2005)
J Neurosci
, vol.25
, pp. 4766-4778
-
-
Reiff, D.F.1
Ihring, A.2
Guerrero, G.3
Isacoff, E.Y.4
Joesch, M.5
Nakai, J.6
Borst, A.7
-
17
-
-
0037012096
-
Selective photostimulation of genetically chARGed neurons
-
Zemelman B.V., Lee G.A., Ng M., and Miesenbock G. Selective photostimulation of genetically chARGed neurons. Neuron 33 (2002) 15-22
-
(2002)
Neuron
, vol.33
, pp. 15-22
-
-
Zemelman, B.V.1
Lee, G.A.2
Ng, M.3
Miesenbock, G.4
-
18
-
-
12344309164
-
Light-activated ion channels for remote control of neuronal firing
-
Banghart M., Borges K., Isacoff E., Trauner D., and Kramer R.H. Light-activated ion channels for remote control of neuronal firing. Nat Neurosci 7 (2004) 1381-1386
-
(2004)
Nat Neurosci
, vol.7
, pp. 1381-1386
-
-
Banghart, M.1
Borges, K.2
Isacoff, E.3
Trauner, D.4
Kramer, R.H.5
-
19
-
-
26444501014
-
Long-term potentiation of exogenous glutamate responses at single dendritic spines
-
Bagal A.A., Kao J.P., Tang C.M., and Thompson S.M. Long-term potentiation of exogenous glutamate responses at single dendritic spines. Proc Natl Acad Sci USA 102 (2005) 14434-14439
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 14434-14439
-
-
Bagal, A.A.1
Kao, J.P.2
Tang, C.M.3
Thompson, S.M.4
-
20
-
-
21844479254
-
Detection of increased local excitatory circuits in the hippocampus during epileptogenesis using focal flash photolysis of caged glutamate
-
Shao L.R., and Dudek F.E. Detection of increased local excitatory circuits in the hippocampus during epileptogenesis using focal flash photolysis of caged glutamate. Epilepsia 46 Suppl 5 (2005) 100-106
-
(2005)
Epilepsia
, vol.46
, Issue.SUPPL. 5
, pp. 100-106
-
-
Shao, L.R.1
Dudek, F.E.2
-
21
-
-
14544308338
-
Excitatory cortical neurons form fine-scale functional networks
-
Yoshimura Y., Dantzker J.L., and Callaway E.M. Excitatory cortical neurons form fine-scale functional networks. Nature 433 (2005) 868-873
-
(2005)
Nature
, vol.433
, pp. 868-873
-
-
Yoshimura, Y.1
Dantzker, J.L.2
Callaway, E.M.3
-
22
-
-
17044431846
-
Remote control of behavior through genetically targeted photostimulation of neurons
-
The authors combined caged ATP and neuron-specific promoters to enable one of the first whole animal in vivo examinations of behavioral circuits by depolarizing groups of neurons. Merely depolarizing specific neurons, even in an animal without a central nervous system, recapitulates known behaviors and indicates that for some behavioral circuits specific neurons, rather than the brain, can control the behavioral response.
-
Lima S.Q., and Miesenbock G. Remote control of behavior through genetically targeted photostimulation of neurons. Cell 121 (2005) 141-152. The authors combined caged ATP and neuron-specific promoters to enable one of the first whole animal in vivo examinations of behavioral circuits by depolarizing groups of neurons. Merely depolarizing specific neurons, even in an animal without a central nervous system, recapitulates known behaviors and indicates that for some behavioral circuits specific neurons, rather than the brain, can control the behavioral response.
-
(2005)
Cell
, vol.121
, pp. 141-152
-
-
Lima, S.Q.1
Miesenbock, G.2
-
23
-
-
26444621497
-
Millisecond-timescale, genetically targeted optical control of neural activity
-
Boyden E.S., Zhang F., Bamberg E., Nagel G., and Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nat Neurosci 8 (2005) 1263-1268
-
(2005)
Nat Neurosci
, vol.8
, pp. 1263-1268
-
-
Boyden, E.S.1
Zhang, F.2
Bamberg, E.3
Nagel, G.4
Deisseroth, K.5
-
24
-
-
29044433616
-
Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses
-
Nagel G., Brauner M., Liewald J.F., Adeishvili N., Bamberg E., and Gottschalk A. Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr Biol 15 (2005) 2279-2284
-
(2005)
Curr Biol
, vol.15
, pp. 2279-2284
-
-
Nagel, G.1
Brauner, M.2
Liewald, J.F.3
Adeishvili, N.4
Bamberg, E.5
Gottschalk, A.6
-
25
-
-
33645974269
-
Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration
-
The authors report that in a genetic mouse model of retinitis pigmentosa induced blindness, expression of ChR2 by viral injection enables the degenerated retinas to respond to a light stimulus and is stable for up to 6 months. The degenerated retinas, rendered sensitive to light again by ChR2, are able to send signals to the visual cortex.
-
Bi A., Cui J., Ma Y.P., Olshevskaya E., Pu M., Dizhoor A.M., and Pan Z.H. Ectopic expression of a microbial-type rhodopsin restores visual responses in mice with photoreceptor degeneration. Neuron 50 (2006) 23-33. The authors report that in a genetic mouse model of retinitis pigmentosa induced blindness, expression of ChR2 by viral injection enables the degenerated retinas to respond to a light stimulus and is stable for up to 6 months. The degenerated retinas, rendered sensitive to light again by ChR2, are able to send signals to the visual cortex.
-
(2006)
Neuron
, vol.50
, pp. 23-33
-
-
Bi, A.1
Cui, J.2
Ma, Y.P.3
Olshevskaya, E.4
Pu, M.5
Dizhoor, A.M.6
Pan, Z.H.7
-
26
-
-
29144480494
-
Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin
-
The authors find that expression of two different light activated proteins, ChR2 and RO4, depolarize and hyperpolarize neurons, respectively, in response to specific wavelengths. In both cultured hippocampal neurons and embryonic chick spinal cords, these proteins can be used to control action potentials and their frequencies, setting the stage for functional examinations of polarization in learning and memory.
-
Li X., Gutierrez D.V., Hanson M.G., Han J., Mark M.D., Chiel H., Hegemann P., Landmesser L.T., and Herlitze S. Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. Proc Natl Acad Sci USA 102 (2005) 17816-17821. The authors find that expression of two different light activated proteins, ChR2 and RO4, depolarize and hyperpolarize neurons, respectively, in response to specific wavelengths. In both cultured hippocampal neurons and embryonic chick spinal cords, these proteins can be used to control action potentials and their frequencies, setting the stage for functional examinations of polarization in learning and memory.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 17816-17821
-
-
Li, X.1
Gutierrez, D.V.2
Hanson, M.G.3
Han, J.4
Mark, M.D.5
Chiel, H.6
Hegemann, P.7
Landmesser, L.T.8
Herlitze, S.9
-
27
-
-
31844446419
-
The mechanisms and functions of activity-dependent long-term potentiation of intrinsic excitability
-
Xu J., and Kang J. The mechanisms and functions of activity-dependent long-term potentiation of intrinsic excitability. Rev Neurosci 16 (2005) 311-323
-
(2005)
Rev Neurosci
, vol.16
, pp. 311-323
-
-
Xu, J.1
Kang, J.2
-
28
-
-
0024968835
-
A general method for site-specific incorporation of unnatural amino acids into proteins
-
Noren C.J., Anthony-Cahill S.J., Griffith M.C., and Schultz P.G. A general method for site-specific incorporation of unnatural amino acids into proteins. Science 244 (1989) 182-188
-
(1989)
Science
, vol.244
, pp. 182-188
-
-
Noren, C.J.1
Anthony-Cahill, S.J.2
Griffith, M.C.3
Schultz, P.G.4
-
29
-
-
0029005830
-
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells
-
Nowak M.W., Kearney P.C., Sampson J.R., Saks M.E., Labarca C.G., Silverman S.K., Zhong W.G., Thorson J., Abelson J.N., Davidson N., et al. Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells. Science 268 (1995) 439-442
-
(1995)
Science
, vol.268
, pp. 439-442
-
-
Nowak, M.W.1
Kearney, P.C.2
Sampson, J.R.3
Saks, M.E.4
Labarca, C.G.5
Silverman, S.K.6
Zhong, W.G.7
Thorson, J.8
Abelson, J.N.9
Davidson, N.10
-
30
-
-
27744608733
-
Cis-trans isomerization at a proline opens the pore of a neurotransmitter-gated ion channel
-
3A, the authors reveal that this proline is implicated as the connection between ligand binding and ungating of the channel. This elegant work shows how fine manipulation of amino acid structure can elucidate functional mechanisms of integral membrane receptors.
-
3A, the authors reveal that this proline is implicated as the connection between ligand binding and ungating of the channel. This elegant work shows how fine manipulation of amino acid structure can elucidate functional mechanisms of integral membrane receptors.
-
(2005)
Nature
, vol.438
, pp. 248-252
-
-
Lummis, S.C.1
Beene, D.L.2
Lee, L.W.3
Lester, H.A.4
Broadhurst, R.W.5
Dougherty, D.A.6
-
31
-
-
25144465496
-
A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor
-
Lummis S.C., D L.B., Harrison N.J., LesterF H.A., and Dougherty D.A. A cation-pi binding interaction with a tyrosine in the binding site of the GABAC receptor. Chem Biol 12 (2005) 993-997
-
(2005)
Chem Biol
, vol.12
, pp. 993-997
-
-
Lummis, S.C.1
Harrison, N.J.2
Lester, F.H.A.3
Dougherty, D.A.4
-
32
-
-
5644237713
-
Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis
-
Beene D.L., Price K.L., Lester H.A., Dougherty D.A., and Lummis S.C. Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis. J Neurosci 24 (2004) 9097-9104
-
(2004)
J Neurosci
, vol.24
, pp. 9097-9104
-
-
Beene, D.L.1
Price, K.L.2
Lester, H.A.3
Dougherty, D.A.4
Lummis, S.C.5
-
33
-
-
0038506126
-
Site-specific incorporation of unnatural amino acids into receptors expressed in Mammalian cells
-
Monahan S.L., Lester H.A., and Dougherty D.A. Site-specific incorporation of unnatural amino acids into receptors expressed in Mammalian cells. Chem Biol 10 (2003) 573-580
-
(2003)
Chem Biol
, vol.10
, pp. 573-580
-
-
Monahan, S.L.1
Lester, H.A.2
Dougherty, D.A.3
-
34
-
-
0035917812
-
Expanding the genetic code of Escherichia coli
-
Wang L., Brock A., Herberich B., and Schultz P.G. Expanding the genetic code of Escherichia coli. Science 292 (2001) 498-500
-
(2001)
Science
, vol.292
, pp. 498-500
-
-
Wang, L.1
Brock, A.2
Herberich, B.3
Schultz, P.G.4
-
36
-
-
0036849244
-
Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells
-
Sakamoto K., Hayashi A., Sakamoto A., Kiga D., Nakayama H., Soma A., Kobayashi T., Kitabatake M., Takio K., Saito K., et al. Site-specific incorporation of an unnatural amino acid into proteins in mammalian cells. Nucleic Acids Res 30 (2002) 4692-4699
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4692-4699
-
-
Sakamoto, K.1
Hayashi, A.2
Sakamoto, A.3
Kiga, D.4
Nakayama, H.5
Soma, A.6
Kobayashi, T.7
Kitabatake, M.8
Takio, K.9
Saito, K.10
-
37
-
-
7744222751
-
A genetically encoded photocaged amino acid
-
Wu N., Deiters A., Cropp T.A., King D., and Schultz P.G. A genetically encoded photocaged amino acid. J Am Chem Soc 126 (2004) 14306-14307
-
(2004)
J Am Chem Soc
, vol.126
, pp. 14306-14307
-
-
Wu, N.1
Deiters, A.2
Cropp, T.A.3
King, D.4
Schultz, P.G.5
-
39
-
-
0037422608
-
Addition of the keto functional group to the genetic code of Escherichia coli
-
Wang L., Zhang Z., Brock A., and Schultz P.G. Addition of the keto functional group to the genetic code of Escherichia coli. Proc Natl Acad Sci USA 100 (2003) 56-61
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 56-61
-
-
Wang, L.1
Zhang, Z.2
Brock, A.3
Schultz, P.G.4
-
40
-
-
31544456661
-
The incorporation of a photoisomerizable amino acid into proteins in E. coli
-
Bose M., Groff D., Xie J., Brustad E., and Schultz P.G. The incorporation of a photoisomerizable amino acid into proteins in E. coli. J Am Chem Soc 128 (2006) 388-389
-
(2006)
J Am Chem Soc
, vol.128
, pp. 388-389
-
-
Bose, M.1
Groff, D.2
Xie, J.3
Brustad, E.4
Schultz, P.G.5
-
41
-
-
18744396951
-
Protein photo-cross-linking in mammalian cells by site-specific incorporation of a photoreactive amino acid
-
Hino N., Okazaki Y., Kobayashi T., Hayashi A., Sakamoto K., and Yokoyama S. Protein photo-cross-linking in mammalian cells by site-specific incorporation of a photoreactive amino acid. Nat Methods 2 (2005) 201-206
-
(2005)
Nat Methods
, vol.2
, pp. 201-206
-
-
Hino, N.1
Okazaki, Y.2
Kobayashi, T.3
Hayashi, A.4
Sakamoto, K.5
Yokoyama, S.6
-
42
-
-
33646038596
-
The genetic incorporation of a distance probe into proteins in Escherichia coli
-
Tsao M.L., Summerer D., Ryu Y., and Schultz P.G. The genetic incorporation of a distance probe into proteins in Escherichia coli. J Am Chem Soc 128 (2006) 4572-4573
-
(2006)
J Am Chem Soc
, vol.128
, pp. 4572-4573
-
-
Tsao, M.L.1
Summerer, D.2
Ryu, Y.3
Schultz, P.G.4
-
43
-
-
2442659130
-
An expanded genetic code with a functional quadruplet codon
-
Anderson J.C., Wu N., Santoro S.W., Lakshman V., King D.S., and Schultz P.G. An expanded genetic code with a functional quadruplet codon. Proc Natl Acad Sci USA 101 (2004) 7566-7571
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 7566-7571
-
-
Anderson, J.C.1
Wu, N.2
Santoro, S.W.3
Lakshman, V.4
King, D.S.5
Schultz, P.G.6
-
44
-
-
23044501802
-
Evolving strategies for enzyme engineering
-
Bloom J.D., Meyer M.M., Meinhold P., Otey C.R., MacMillan D., and Arnold F.H. Evolving strategies for enzyme engineering. Curr Opin Struct Biol 15 (2005) 447-452
-
(2005)
Curr Opin Struct Biol
, vol.15
, pp. 447-452
-
-
Bloom, J.D.1
Meyer, M.M.2
Meinhold, P.3
Otey, C.R.4
MacMillan, D.5
Arnold, F.H.6
-
45
-
-
0033152865
-
Protein evolution by molecular breeding
-
Minshull J., and Stemmer W.P. Protein evolution by molecular breeding. Curr Opin Chem Biol 3 (1999) 284-290
-
(1999)
Curr Opin Chem Biol
, vol.3
, pp. 284-290
-
-
Minshull, J.1
Stemmer, W.P.2
-
46
-
-
10044227172
-
Evolution of new nonantibody proteins via iterative somatic hypermutation
-
Wang L., Jackson W.C., Steinbach P.A., and Tsien R.Y. Evolution of new nonantibody proteins via iterative somatic hypermutation. Proc Natl Acad Sci USA 101 (2004) 16745-16749
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 16745-16749
-
-
Wang, L.1
Jackson, W.C.2
Steinbach, P.A.3
Tsien, R.Y.4
-
47
-
-
0036674618
-
AID and mismatch repair in antibody diversification
-
Martin A., and Scharff M.D. AID and mismatch repair in antibody diversification. Nat Rev Immunol 2 (2002) 605-614
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 605-614
-
-
Martin, A.1
Scharff, M.D.2
-
48
-
-
13444259474
-
Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation
-
Neuberger M.S., Di Noia J.M., Beale R.C., Williams G.T., Yang Z., and Rada C. Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation. Nat Rev Immunol 5 (2005) 171-178
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 171-178
-
-
Neuberger, M.S.1
Di Noia, J.M.2
Beale, R.C.3
Williams, G.T.4
Yang, Z.5
Rada, C.6
-
49
-
-
33644636246
-
AID in somatic hypermutation and class switch recombination
-
Longerich S., Basu U., Alt F., and Storb U. AID in somatic hypermutation and class switch recombination. Curr Opin Immunol 18 (2006) 164-174
-
(2006)
Curr Opin Immunol
, vol.18
, pp. 164-174
-
-
Longerich, S.1
Basu, U.2
Alt, F.3
Storb, U.4
-
50
-
-
33644621127
-
Discovery and properties of GFP-like proteins from nonbioluminescent anthozoa
-
Lukyanov K.A., Chudakov D.M., Fradkov A.F., Labas Y.A., Matz M.V., and Lukyanov S. Discovery and properties of GFP-like proteins from nonbioluminescent anthozoa. Methods Biochem Anal 47 (2006) 121-138
-
(2006)
Methods Biochem Anal
, vol.47
, pp. 121-138
-
-
Lukyanov, K.A.1
Chudakov, D.M.2
Fradkov, A.F.3
Labas, Y.A.4
Matz, M.V.5
Lukyanov, S.6
-
51
-
-
11144267737
-
Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein
-
Shaner N.C., Campbell R.E., Steinbach P.A., Giepmans B.N., Palmer A.E., and Tsien R.Y. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol 22 (2004) 1567-1572
-
(2004)
Nat Biotechnol
, vol.22
, pp. 1567-1572
-
-
Shaner, N.C.1
Campbell, R.E.2
Steinbach, P.A.3
Giepmans, B.N.4
Palmer, A.E.5
Tsien, R.Y.6
-
52
-
-
3242706582
-
Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins
-
Nagai T., Yamada S., Tominaga T., Ichikawa M., and Miyawaki A. Expanded dynamic range of fluorescent indicators for Ca(2+) by circularly permuted yellow fluorescent proteins. Proc Natl Acad Sci USA 101 (2004) 10554-10559
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10554-10559
-
-
Nagai, T.1
Yamada, S.2
Tominaga, T.3
Ichikawa, M.4
Miyawaki, A.5
-
54
-
-
16644367431
-
Functional fluorescent Ca2+ indicator proteins in transgenic mice under TET control
-
Hasan M.T., Friedrich R.W., Euler T., Larkum M.E., Giese G., Both M., Duebel J., Waters J., Bujard H., Griesbeck O., et al. Functional fluorescent Ca2+ indicator proteins in transgenic mice under TET control. PLoS Biol 2 (2004) e163
-
(2004)
PLoS Biol
, vol.2
-
-
Hasan, M.T.1
Friedrich, R.W.2
Euler, T.3
Larkum, M.E.4
Giese, G.5
Both, M.6
Duebel, J.7
Waters, J.8
Bujard, H.9
Griesbeck, O.10
-
55
-
-
10644234677
-
Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor
-
Palmer A.E., Jin C., Reed J.C., and Tsien R.Y. Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor. Proc Natl Acad Sci USA 101 (2004) 17404-17409
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 17404-17409
-
-
Palmer, A.E.1
Jin, C.2
Reed, J.C.3
Tsien, R.Y.4
-
56
-
-
33646570865
-
Ca(2+) indicators based on computationally redesigned calmodulin-Peptide pairs
-
Palmer A.E., Giacomello M., Kortemme T., Hires S.A., Lev-Ram V., Baker D., and Tsien R.Y. Ca(2+) indicators based on computationally redesigned calmodulin-Peptide pairs. Chem Biol 13 (2006) 521-530
-
(2006)
Chem Biol
, vol.13
, pp. 521-530
-
-
Palmer, A.E.1
Giacomello, M.2
Kortemme, T.3
Hires, S.A.4
Lev-Ram, V.5
Baker, D.6
Tsien, R.Y.7
-
57
-
-
33645283923
-
Genetically encoded fluorescent indicator for intracellular hydrogen peroxide
-
Belousov V.V., Fradkov A.F., Lukyanov K.A., Staroverov D.B., Shakhbazov K.S., Terskikh A.V., and Lukyanov S. Genetically encoded fluorescent indicator for intracellular hydrogen peroxide. Nat Methods 3 (2006) 281-286
-
(2006)
Nat Methods
, vol.3
, pp. 281-286
-
-
Belousov, V.V.1
Fradkov, A.F.2
Lukyanov, K.A.3
Staroverov, D.B.4
Shakhbazov, K.S.5
Terskikh, A.V.6
Lukyanov, S.7
-
58
-
-
33749076327
-
-
Chambers JJ, Banghart MR, Trauner D, Kramer RH: Light-induced depolarization of neurons using a modified Shaker K+ channel and a molecular photoswitch. J Neurophysiol 2006; DOI:10.1152/jn.00318.2006. By altering the cation specificity of the Shaker pore of the existing synthetic channel H-SPARK (hyperpolarizing SPARK), the authors create D-SPARK (depolarizing SPARK). D-SPARK allows all cations to flow, leading to depolarization rather than hyperpolarization upon light application. This pair of synthetic channels can be used simultaneously in different neurons, and can also be closed by application of specific wavelength light, unlike other light-controlled systems.
-
-
-
|