Light activation of Channelrhodopsin-2 in excitable cells of caenorhabditis elegans triggers rapid behavioral responses

Current Biology

Volumn 15, Issue 24, 2005, Pages 2279-2284

  Nagel, Georg ^a,c   Brauner, Martin ^b   Liewald, Jana F ^b   Adeishvili, Nona ^a   Bamberg, Ernst ^a,b   Gottschalk, Alexander ^b  

^a MAX PLANCK INSTITUTE OF BIOPHYSICS   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; CAENORHABDITIS ELEGANS; CHLAMYDOMONAS REINHARDTII; CHLOROPHYTA;

EID: 29044433616     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2005.11.032     Document Type: Article

References (27)

1. J.E. Richmond, W.S. Davis, and E.M. Jorgensen UNC-13 is required for synaptic vesicle fusion in C. elegans Nat. Neurosci. 2 1999 959 964
2. J.E. Richmond, and E.M. Jorgensen One GABA and two acetylcholine receptors function at the C. elegans neuromuscular junction Nat. Neurosci. 2 1999 791 797
3. G. Nagel, T. Szellas, W. Huhn, S. Kateriya, N. Adeishvili, P. Berthold, D. Ollig, P. Hegemann, and E. Bamberg Channelrhodopsin-2, a directly light-gated cation-selective membrane channel Proc. Natl. Acad. Sci. USA 100 2003 13940 13945
4. G. Nagel, D. Ollig, M. Fuhrmann, S. Kateriya, A.M. Musti, E. Bamberg, and P. Hegemann Channelrhodopsin-1: A light-gated proton channel in green algae Science 296 2002 2395 2398
5. D. Oesterhelt, and W. Stoeckenius Rhodopsin-like protein from the purple membrane of Halobacterium halobium Nat. New Biol. 233 1971 149 152
6. M. Huang, and M. Chalfie Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans Nature 367 1994 467 470
7. H.J. Butt, K. Fendler, E. Bamberg, J. Tittor, and D. Oesterhelt Aspartic acids 96 and 85 play a central role in the function of bacteriorhodopsin as a proton pump EMBO J. 8 1989 1657 1663
8. E.S. Boyden, F. Zhang, E. Bamberg, G. Nagel, and K. Deisseroth Millisecond-timescale, genetically targeted optical control of neural activity Nat. Neurosci. 8 2005 1263 1268
9. C.I. Bargmann Neurobiology of the Caenorhabditis elegans genome Science 282 1998 2028 2033
10. A. Yuan, C.M. Santi, A. Wei, Z.W. Wang, K. Pollak, M. Nonet, L. Kaczmarek, C.M. Crowder, and L. Salkoff The sodium-activated potassium channel is encoded by a member of the Slo gene family Neuron 37 2003 765 773
11. A. Yuan, M. Dourado, A. Butler, N. Walton, A. Wei, and L. Salkoff SLO-2, a K+ channel with an unusual Cl- dependence Nat. Neurosci. 3 2000 771 779
12. R.Y. Lee, L. Lobel, M. Hengartner, H.R. Horvitz, and L. Avery Mutations in the alpha1 subunit of an L-type voltage-activated Ca2+ channel cause myotonia in Caenorhabditis elegans EMBO J. 16 1997 6066 6076
13. E.A. Mathews, E. Garcia, C.M. Santi, G.P. Mullen, C. Thacker, D.G. Moerman, and T.P. Snutch Critical residues of the Caenorhabditis elegans unc-2 voltage-gated calcium channel that affect behavioral and physiological properties J. Neurosci. 23 2003 6537 6545
14. W.R. Schafer, and C.J. Kenyon A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans Nature 375 1995 73 78
15. E.B. Maryon, R. Coronado, and P. Anderson unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction J. Cell Biol. 134 1996 885 893
16. G.G. Ernstrom, and M. Chalfie Genetics of sensory mechanotransduction Annu. Rev. Genet. 36 2002 411 453
17. N. Wittenburg, and R. Baumeister Thermal avoidance in Caenorhabditis elegans: An approach to the study of nociception Proc. Natl. Acad. Sci. USA 96 1999 10477 10482
18. A.H. Burr The photomovement of Caenorhabditis elegans, a nematode which lacks ocelli. Proof that the response is to light not radiant heating Photochem. Photobiol. 41 1985 577 582
19. C.H. Rankin, C.D. Beck, and C.M. Chiba Caenorhabditis elegans: A new model system for the study of learning and memory Behav. Brain Res. 37 1990 89 92
20. R. O'Hagan, M. Chalfie, and M.B. Goodman The MEC-4 DEG/ENaC channel of Caenorhabditis elegans touch receptor neurons transduces mechanical signals Nat. Neurosci. 8 2005 43 50
21. H. Suzuki, R. Kerr, L. Bianchi, C. Frokjaer-Jensen, D. Slone, J. Xue, B. Gerstbrein, M. Driscoll, and W.R. Schafer In vivo imaging of C. elegans mechanosensory neurons demonstrates a specific role for the MEC-4 channel in the process of gentle touch sensation Neuron 39 2003 1005 1017
22. L. Bianchi, B. Gerstbrein, C. Frokjaer-Jensen, D.C. Royal, G. Mukherjee, M.A. Royal, J. Xue, W.R. Schafer, and M. Driscoll The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: Implications for necrosis initiation Nat. Neurosci. 7 2004 1337 1344
23. M. Chalfie, and J. Sulston Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans Dev. Biol. 82 1981 358 370
24. K. Shimono, T. Hayashi, Y. Ikeura, Y. Sudo, M. Iwamoto, and N. Kamo Importance of the broad regional interaction for spectral tuning in Natronobacterium pharaonis phoborhodopsin (sensory rhodopsin II) J. Biol. Chem. 278 2003 23882 23889
25. C.I. Bargmann, and L. Avery Laser killing of cells in Caenorhabditis elegans Methods Cell Biol. 48 1995 225 250
26. D. Tobin, D. Madsen, A. Kahn-Kirby, E. Peckol, G. Moulder, R. Barstead, A. Maricq, and C. Bargmann Combinatorial expression of TRPV channel proteins defines their sensory functions and subcellular localization in C. elegans neurons Neuron 35 2002 307 318
27. S.Q. Lima, and G. Miesenböck Remote control of behavior through genetically targeted photostimulation of neurons Cell 121 2005 141 152