Promyelocytic leukemia activates Chk2 by mediating Chk2 autophosphorylation

Journal of Biological Chemistry

Volumn 281, Issue 36, 2006, Pages 26645-26654

  Yang, Shutong ^a   Jeong, Jae Hoon ^a   Brown, Alexandra L ^a   Lee, Chang Hun ^a,c   Pandolfi, Pier Paolo ^b   Chung, Jay H ^a   Kim, Myung K ^a  

^a NIH/NHLBI/LBG   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c National Cancer Center   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE PROMYELOCYTIC LEUKEMIA (APL); ATAXIA TELANGIECTASIA MUTATED (ATM); PROMYELOCYTIC LEUKEMIA (PML); RETINOIC ACID RECEPTOR (RARΑ);

CELLS; CHROMOSOMES; DISEASE CONTROL; DNA; MUTAGENESIS; PHOSPHORESCENCE; TUMORS;

PROTEINS;

CHECKPOINT KINASE 2; PROTEIN P53; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA;

ALLELE; ANIMAL CELL; ARTICLE; ATAXIA TELANGIECTASIA; AUTOPHOSPHORYLATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; GENE MUTATION; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; REGULATORY MECHANISM;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HELA CELLS; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, RETINOIC ACID; RECOMBINANT FUSION PROTEINS; TRANSCRIPTION FACTORS; TRETINOIN; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 33748747143     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604391200     Document Type: Article

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