메뉴 건너뛰기




Volumn 41, Issue 10, 2006, Pages 2103-2112

Agitation effects on morphology and protein productive fractions of filamentous and pelleted growth forms of recombinant Aspergillus niger

Author keywords

Agitation; Glucose oxidase; Morphology; Protein excretion; Recombinant Aspergillus niger

Indexed keywords

BIOMASS; CARBOXYLIC ACIDS; GENETIC ENGINEERING; GLUCOSE; MORPHOLOGY; SHEAR STRESS;

EID: 33748520515     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2006.05.024     Document Type: Article
Times cited : (55)

References (46)
  • 1
    • 0023463798 scopus 로고
    • Improvement of enzyme production in Aspergillus
    • Finkelstein D.B. Improvement of enzyme production in Aspergillus. Antonie van Leeuwenhoek 53 (1987) 349-352
    • (1987) Antonie van Leeuwenhoek , vol.53 , pp. 349-352
    • Finkelstein, D.B.1
  • 2
    • 0031307441 scopus 로고    scopus 로고
    • The molecular biology of secreted enzyme production by fungi
    • Archer D.B., and Peberdy J.F. The molecular biology of secreted enzyme production by fungi. Crit Rev Biotechnol 17 (1997) 273-306
    • (1997) Crit Rev Biotechnol , vol.17 , pp. 273-306
    • Archer, D.B.1    Peberdy, J.F.2
  • 4
    • 11944256451 scopus 로고
    • Improved production of chymosin in Aspergillus by expression as a glucoamylase-chymosin fusion
    • Ward M., Wilson L.J., Kodama K.H., Rey M.W., and Berka R.M. Improved production of chymosin in Aspergillus by expression as a glucoamylase-chymosin fusion. Bio/Technology 8 (1990) 435-440
    • (1990) Bio/Technology , vol.8 , pp. 435-440
    • Ward, M.1    Wilson, L.J.2    Kodama, K.H.3    Rey, M.W.4    Berka, R.M.5
  • 7
    • 0142232284 scopus 로고    scopus 로고
    • The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi
    • Joosten V., Lokman C., van den Hondel C.A.M.J.J., and Punt P.J. The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi. Microb Cell Fact 2 (2003) 1
    • (2003) Microb Cell Fact , vol.2 , pp. 1
    • Joosten, V.1    Lokman, C.2    van den Hondel, C.A.M.J.J.3    Punt, P.J.4
  • 8
    • 0141855304 scopus 로고    scopus 로고
    • Evaluation of Aspergillus niger as host for virus-like particle production, using the hepatitis B surface antigen as a model
    • Plüddemann A., and van Zyl W.H. Evaluation of Aspergillus niger as host for virus-like particle production, using the hepatitis B surface antigen as a model. Curr Genet 43 (2003) 439-446
    • (2003) Curr Genet , vol.43 , pp. 439-446
    • Plüddemann, A.1    van Zyl, W.H.2
  • 9
    • 0026683946 scopus 로고
    • Proteolytic degradation of heterologous proteins expressed in Aspergillus niger
    • Archer D.B., MacKenzie D.A., Jeenes D.J., and Roberts I.N. Proteolytic degradation of heterologous proteins expressed in Aspergillus niger. Biotechnol Lett 14 (1992) 357-362
    • (1992) Biotechnol Lett , vol.14 , pp. 357-362
    • Archer, D.B.1    MacKenzie, D.A.2    Jeenes, D.J.3    Roberts, I.N.4
  • 10
    • 0034092485 scopus 로고    scopus 로고
    • Increased heterologous protein production in Aspergillus niger fermentation through extracellular proteases inhibition by pelleted growth
    • Xu J., Wang L., Ridgway D., Gu T., and Moo-Young M. Increased heterologous protein production in Aspergillus niger fermentation through extracellular proteases inhibition by pelleted growth. Biotechnol Prog 16 (2000) 222-227
    • (2000) Biotechnol Prog , vol.16 , pp. 222-227
    • Xu, J.1    Wang, L.2    Ridgway, D.3    Gu, T.4    Moo-Young, M.5
  • 11
    • 0034764850 scopus 로고    scopus 로고
    • Enhanced heterologous protein production in Aspergillus niger through pH control of extracellular protease activity
    • O'Donnell D., Wang L., Xu J., Ridgway D., Gu T., and Moo-Young M. Enhanced heterologous protein production in Aspergillus niger through pH control of extracellular protease activity. Biochem Eng J 8 (2001) 187-193
    • (2001) Biochem Eng J , vol.8 , pp. 187-193
    • O'Donnell, D.1    Wang, L.2    Xu, J.3    Ridgway, D.4    Gu, T.5    Moo-Young, M.6
  • 12
    • 0030750269 scopus 로고    scopus 로고
    • Disruption of three acid proteases in Aspergillus niger: effects on protease spectrum, intracellular proteolysis, and degradation of target proteins
    • van den Hombergh J.P.T.W., Sollewijn Gelpke M.D., van de Vondervoort P.J.I., Buxton F.P., and Visser J. Disruption of three acid proteases in Aspergillus niger: effects on protease spectrum, intracellular proteolysis, and degradation of target proteins. Eur J Biochem 247 (1997) 605-613
    • (1997) Eur J Biochem , vol.247 , pp. 605-613
    • van den Hombergh, J.P.T.W.1    Sollewijn Gelpke, M.D.2    van de Vondervoort, P.J.I.3    Buxton, F.P.4    Visser, J.5
  • 14
    • 20644462160 scopus 로고    scopus 로고
    • Bioprocessing strategies to improve heterologous protein production in filamentous fungal fermentations
    • Wang L., Ridgway D., Gu T., and Moo-Young M. Bioprocessing strategies to improve heterologous protein production in filamentous fungal fermentations. Biotechnol Adv 23 (2005) 115-129
    • (2005) Biotechnol Adv , vol.23 , pp. 115-129
    • Wang, L.1    Ridgway, D.2    Gu, T.3    Moo-Young, M.4
  • 17
    • 0022752488 scopus 로고
    • Investigations of oxygen transfer into Penicillium chrysogenum pellets by microprobe measurements
    • Wittler R., Baumgartl H., Lübbers D.W., and Schügerl K. Investigations of oxygen transfer into Penicillium chrysogenum pellets by microprobe measurements. Biotechnol Bioeng 28 (1986) 1024-1036
    • (1986) Biotechnol Bioeng , vol.28 , pp. 1024-1036
    • Wittler, R.1    Baumgartl, H.2    Lübbers, D.W.3    Schügerl, K.4
  • 19
    • 15344344498 scopus 로고    scopus 로고
    • Model-based prediction of substrate conversion and protein synthesis and excretion in recombinant Aspergillus niger biopellets
    • Rinas U., El-Enshasy H., Emmler M., Hille A., Hempel D.C., and Horn H. Model-based prediction of substrate conversion and protein synthesis and excretion in recombinant Aspergillus niger biopellets. Chem Eng Sci 60 (2005) 2729-2739
    • (2005) Chem Eng Sci , vol.60 , pp. 2729-2739
    • Rinas, U.1    El-Enshasy, H.2    Emmler, M.3    Hille, A.4    Hempel, D.C.5    Horn, H.6
  • 20
    • 29544440824 scopus 로고    scopus 로고
    • Oxygen profiles and biomass distribution in biopellets of Aspergillus niger
    • Hille A., Neu T.R., Hempel D.C., and Horn H. Oxygen profiles and biomass distribution in biopellets of Aspergillus niger. Biotechnol Bioeng 92 (2005) 614-623
    • (2005) Biotechnol Bioeng , vol.92 , pp. 614-623
    • Hille, A.1    Neu, T.R.2    Hempel, D.C.3    Horn, H.4
  • 21
    • 0032873845 scopus 로고    scopus 로고
    • Fungal morphology in submerged cultures and its relation to glucose oxidase excretion by recombinant Aspergillus niger
    • El-Enshasy H., Hellmuth K., and Rinas U. Fungal morphology in submerged cultures and its relation to glucose oxidase excretion by recombinant Aspergillus niger. Appl Biochem Biotechnol 81 (1999) 1-11
    • (1999) Appl Biochem Biotechnol , vol.81 , pp. 1-11
    • El-Enshasy, H.1    Hellmuth, K.2    Rinas, U.3
  • 23
    • 0031608229 scopus 로고    scopus 로고
    • Influence of the process parameters on the morphology and enzyme production of Aspergilli
    • Schügerl K., Gerlach S.R., and Siedenberg D. Influence of the process parameters on the morphology and enzyme production of Aspergilli. Adv Biochem Eng Biotechnol 60 (1998) 195-266
    • (1998) Adv Biochem Eng Biotechnol , vol.60 , pp. 195-266
    • Schügerl, K.1    Gerlach, S.R.2    Siedenberg, D.3
  • 24
    • 0036090485 scopus 로고    scopus 로고
    • Protease secretion in glucoamylase producer Aspergillus niger cultures: fungal morphology and inoculum effects
    • Papagianni M., and Moo-Young M. Protease secretion in glucoamylase producer Aspergillus niger cultures: fungal morphology and inoculum effects. Process Biochem 37 (2002) 1271-1278
    • (2002) Process Biochem , vol.37 , pp. 1271-1278
    • Papagianni, M.1    Moo-Young, M.2
  • 25
    • 0032031899 scopus 로고    scopus 로고
    • Influence of morphology on product formation in Aspergillus awamori during submerged fermentations
    • Johansen C.L., Coolen L., and Hunik J.H. Influence of morphology on product formation in Aspergillus awamori during submerged fermentations. Biotechnol Prog 14 (1998) 233-240
    • (1998) Biotechnol Prog , vol.14 , pp. 233-240
    • Johansen, C.L.1    Coolen, L.2    Hunik, J.H.3
  • 26
    • 0343036306 scopus 로고    scopus 로고
    • Production of xylanase by Aspergillus awamori on synthetic medium in stirred tank and airlift tower loop reactors: the influence of stirrer speed and phosphate concentration
    • Siedenberg D., Gerlach S.R., Weigel B., Schügerl K., Giuseppin M.L.F., and Hunik J. Production of xylanase by Aspergillus awamori on synthetic medium in stirred tank and airlift tower loop reactors: the influence of stirrer speed and phosphate concentration. J Biotechnol 56 (1997) 103-114
    • (1997) J Biotechnol , vol.56 , pp. 103-114
    • Siedenberg, D.1    Gerlach, S.R.2    Weigel, B.3    Schügerl, K.4    Giuseppin, M.L.F.5    Hunik, J.6
  • 27
    • 0032143673 scopus 로고    scopus 로고
    • Influence of reactor systems on the morphology of Aspergillus awamori. Application of neural network and cluster analysis for characterization of fungal morphology
    • Gerlach S.R., Siedenberg D., Gerlach D., Schügerl K., Giuseppin M.L.F., and Hunik J. Influence of reactor systems on the morphology of Aspergillus awamori. Application of neural network and cluster analysis for characterization of fungal morphology. Process Biochem 33 (1998) 601-615
    • (1998) Process Biochem , vol.33 , pp. 601-615
    • Gerlach, S.R.1    Siedenberg, D.2    Gerlach, D.3    Schügerl, K.4    Giuseppin, M.L.F.5    Hunik, J.6
  • 28
    • 0344530293 scopus 로고    scopus 로고
    • Effects of process parameters on heterologous protein production in Aspergillus niger fermentation
    • Wang L., Ridgway D., Gu T., and Moo-Young M. Effects of process parameters on heterologous protein production in Aspergillus niger fermentation. J Chem Technol Biotechnol 78 (2003) 1259-1266
    • (2003) J Chem Technol Biotechnol , vol.78 , pp. 1259-1266
    • Wang, L.1    Ridgway, D.2    Gu, T.3    Moo-Young, M.4
  • 29
    • 0032549163 scopus 로고    scopus 로고
    • Effects of dissolved oxygen tension and mechanical forces on fungal morphology in submerged fermentation
    • Cui Y.Q., van der Lans R.G.J.M., and Luyben K.C.A.M. Effects of dissolved oxygen tension and mechanical forces on fungal morphology in submerged fermentation. Biotechnol Bioeng 57 (1998) 409-419
    • (1998) Biotechnol Bioeng , vol.57 , pp. 409-419
    • Cui, Y.Q.1    van der Lans, R.G.J.M.2    Luyben, K.C.A.M.3
  • 30
    • 0033589831 scopus 로고    scopus 로고
    • Effect of oxygen enrichment on morphology, growth, and heterologous protein production in chemostat cultures of Aspergillus niger B1-D
    • Wongwicharn A., McNeil B., and Harvey L.M. Effect of oxygen enrichment on morphology, growth, and heterologous protein production in chemostat cultures of Aspergillus niger B1-D. Biotechnol Bioeng 65 (1999) 416-424
    • (1999) Biotechnol Bioeng , vol.65 , pp. 416-424
    • Wongwicharn, A.1    McNeil, B.2    Harvey, L.M.3
  • 31
    • 0345096555 scopus 로고    scopus 로고
    • Effects of oxidative stress on production of heterologous and native protein, and culture morphology in batch and chemostat cultures of Aspergillus niger (B1-D)
    • Bai Z., Harvey L.M., White S., and McNeil B. Effects of oxidative stress on production of heterologous and native protein, and culture morphology in batch and chemostat cultures of Aspergillus niger (B1-D). Enzyme Microb Technol 34 (2004) 10-21
    • (2004) Enzyme Microb Technol , vol.34 , pp. 10-21
    • Bai, Z.1    Harvey, L.M.2    White, S.3    McNeil, B.4
  • 32
    • 0029669455 scopus 로고    scopus 로고
    • Morphology and physiology of an α-amylase producing strain of Aspergillus oryzae during batch cultivations
    • Carlsen M., Spohr A.B., Nielsen J., and Villadsen J. Morphology and physiology of an α-amylase producing strain of Aspergillus oryzae during batch cultivations. Biotechnol Bioeng 49 (1996) 266-276
    • (1996) Biotechnol Bioeng , vol.49 , pp. 266-276
    • Carlsen, M.1    Spohr, A.B.2    Nielsen, J.3    Villadsen, J.4
  • 33
    • 0032126787 scopus 로고    scopus 로고
    • Influence of fermentation conditions and scale on the submerged fermentation of Aspergillus awamori
    • Cui Y.Q., van der Lans R.G.J.M., Giuseppin M.L.F., and Luyben K.C.A.M. Influence of fermentation conditions and scale on the submerged fermentation of Aspergillus awamori. Enzyme Microb Technol 23 (1998) 157-167
    • (1998) Enzyme Microb Technol , vol.23 , pp. 157-167
    • Cui, Y.Q.1    van der Lans, R.G.J.M.2    Giuseppin, M.L.F.3    Luyben, K.C.A.M.4
  • 34
    • 0024279130 scopus 로고
    • Morphology and growth of Aspergillus niger ATCC 26036 cultivated at several shear rates
    • Mitard A., and Riba J.P. Morphology and growth of Aspergillus niger ATCC 26036 cultivated at several shear rates. Biotechnol Bioeng 32 (1988) 835-840
    • (1988) Biotechnol Bioeng , vol.32 , pp. 835-840
    • Mitard, A.1    Riba, J.P.2
  • 35
    • 0027987158 scopus 로고
    • Analysis of pellet formation of Aspergillus niger based on shear stress
    • Fujita M., Iwahori K., Tatsuta S., and Yamakawa K. Analysis of pellet formation of Aspergillus niger based on shear stress. J Ferment Bioeng 78 (1994) 368-373
    • (1994) J Ferment Bioeng , vol.78 , pp. 368-373
    • Fujita, M.1    Iwahori, K.2    Tatsuta, S.3    Yamakawa, K.4
  • 36
    • 0031554874 scopus 로고    scopus 로고
    • Effect of agitation intensities on fungal morphology of submerged fermentation
    • Cui Y.Q., van der Lans R.G.J.M., and Luyben K.C.A.M. Effect of agitation intensities on fungal morphology of submerged fermentation. Biotechnol Bioeng 55 (1997) 715-726
    • (1997) Biotechnol Bioeng , vol.55 , pp. 715-726
    • Cui, Y.Q.1    van der Lans, R.G.J.M.2    Luyben, K.C.A.M.3
  • 37
    • 0032839318 scopus 로고    scopus 로고
    • Secretion of heterologous and native proteins, growth and morphology in batch cultures of Aspergillus niger B1-D at varying agitation rates
    • Wongwicharn A., Harvey L.M., and McNeil B. Secretion of heterologous and native proteins, growth and morphology in batch cultures of Aspergillus niger B1-D at varying agitation rates. J Chem Technol Biotechnol 74 (1999) 821-828
    • (1999) J Chem Technol Biotechnol , vol.74 , pp. 821-828
    • Wongwicharn, A.1    Harvey, L.M.2    McNeil, B.3
  • 38
    • 0033585875 scopus 로고    scopus 로고
    • Effects of agitation intensity on mycelial morphology and protein production in chemostat cultures of recombinant Aspergillus oryzae
    • Amanullah A., Blair R., Nienow A.W., and Thomas C.R. Effects of agitation intensity on mycelial morphology and protein production in chemostat cultures of recombinant Aspergillus oryzae. Biotechnol Bioeng 62 (1999) 434-446
    • (1999) Biotechnol Bioeng , vol.62 , pp. 434-446
    • Amanullah, A.1    Blair, R.2    Nienow, A.W.3    Thomas, C.R.4
  • 39
    • 0037197173 scopus 로고    scopus 로고
    • Dependence of morphology on agitation intensity in fed-batch cultures of Aspergillus oryzae and its implications for recombinant protein production
    • Amanullah A., Christensen L.H., Hansen K., Nienow A.W., and Thomas C.R. Dependence of morphology on agitation intensity in fed-batch cultures of Aspergillus oryzae and its implications for recombinant protein production. Biotechnol Bioeng 77 (2002) 815-826
    • (2002) Biotechnol Bioeng , vol.77 , pp. 815-826
    • Amanullah, A.1    Christensen, L.H.2    Hansen, K.3    Nienow, A.W.4    Thomas, C.R.5
  • 40
    • 0028820720 scopus 로고
    • Optimization of glucose oxidase production by Aspergillus niger using genetic- and process-engineering techniques
    • Hellmuth K., Pluschkell S., Jung J.-K., Ruttkowski E., and Rinas U. Optimization of glucose oxidase production by Aspergillus niger using genetic- and process-engineering techniques. Appl Microbiol Biotechnol 43 (1995) 978-984
    • (1995) Appl Microbiol Biotechnol , vol.43 , pp. 978-984
    • Hellmuth, K.1    Pluschkell, S.2    Jung, J.-K.3    Ruttkowski, E.4    Rinas, U.5
  • 41
    • 0035102590 scopus 로고    scopus 로고
    • GpdA-promoter controlled production of glucose oxidase by recombinant Aspergillus niger using nonglucose carbon sources
    • El-Enshasy H., Hellmuth K., and Rinas U. GpdA-promoter controlled production of glucose oxidase by recombinant Aspergillus niger using nonglucose carbon sources. Appl Biochem Biotechnol 90 (2001) 57-66
    • (2001) Appl Biochem Biotechnol , vol.90 , pp. 57-66
    • El-Enshasy, H.1    Hellmuth, K.2    Rinas, U.3
  • 42
    • 15844418083 scopus 로고    scopus 로고
    • Kinetics of glucose oxidase excretion by recombinant Aspergillus niger
    • Pluschkell S., Hellmuth K., and Rinas U. Kinetics of glucose oxidase excretion by recombinant Aspergillus niger. Biotechnol Bioeng 51 (1996) 215-220
    • (1996) Biotechnol Bioeng , vol.51 , pp. 215-220
    • Pluschkell, S.1    Hellmuth, K.2    Rinas, U.3
  • 43
    • 0030153138 scopus 로고    scopus 로고
    • Local power uptake in gas-liquid systems with single and multiple rushton turbines
    • Cui Y.Q., van der Lans R.G.J.M., and Luyben K.C.A.M. Local power uptake in gas-liquid systems with single and multiple rushton turbines. Chem Eng Sci 51 (1996) 2631-2636
    • (1996) Chem Eng Sci , vol.51 , pp. 2631-2636
    • Cui, Y.Q.1    van der Lans, R.G.J.M.2    Luyben, K.C.A.M.3
  • 45
    • 0023229174 scopus 로고
    • Application of carbon balance to submerged citric acid production by Aspergillus niger
    • Nowakowska-Waszczuk A., and Sokolowski A. Application of carbon balance to submerged citric acid production by Aspergillus niger. Appl Microbiol Biotechnol 26 (1987) 363-364
    • (1987) Appl Microbiol Biotechnol , vol.26 , pp. 363-364
    • Nowakowska-Waszczuk, A.1    Sokolowski, A.2
  • 46
    • 0029891385 scopus 로고    scopus 로고
    • Fluorescence microscopic investigation of Aspergillus awamori growing on synthetic and complex media and producing xylanase
    • Freudenberg S., Fasold K.-I., Müller S.R., Siedenberg D., Kretzmer G., Schügerl K., et al. Fluorescence microscopic investigation of Aspergillus awamori growing on synthetic and complex media and producing xylanase. J Biotechnol 46 (1996) 265-273
    • (1996) J Biotechnol , vol.46 , pp. 265-273
    • Freudenberg, S.1    Fasold, K.-I.2    Müller, S.R.3    Siedenberg, D.4    Kretzmer, G.5    Schügerl, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.