Production of tissue plasminogen activator (t-PA) in Aspergillus niger

Biotechnology and Bioengineering

Volumn 76, Issue 2, 2001, Pages 164-174

  Wiebe, Marilyn G ^a   Karandikar, Atul ^a   Robson, Geoff D ^a   Trinci, Anthony P J ^a   Candia, Juana L Flores ^b   Trappe, Susanne ^b   Wallis, Gregg ^b   Rinas, Ursula ^b   Derkx, Patrick M F ^c   Madrid, Susan M ^c   Sisniega, Heidi ^d   Faus, Ignacio ^d   Montijn, Roy ^e   van den Hondel, Cees A M J J ^e   Punt, Peter J ^e  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c DANISCO A S   (Denmark)

^d Department of Biotechnology   (Spain)

^e TNO   (Netherlands)

Author keywords

Aspergillus niger; Cyclophilin B; Protease deficient; Tissue plasminogen activator (t PA); Unfolded protein response (UPR)

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

BIOMASS; CELL CULTURE; GENES; GLUCOSE; MOLECULAR WEIGHT; TISSUE;

BIOTECHNOLOGY;

CYCLOPHILIN B; GLUCOSE; PEPTONE; PROTEINASE; SOYBEAN PROTEIN; TISSUE PLASMINOGEN ACTIVATOR;

ARTICLE; ASPERGILLUS NIGER; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOENGINEERING; BIOMASS; CHEMOSTAT; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION REGULATION; MAMMAL CELL; NONHUMAN; PRODUCTIVITY; PROTEIN DEGRADATION; PROTEIN FOLDING;

ASPERGILLUS NIGER; BIOMASS; BIOREACTORS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CYCLOPHILINS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENES, FUNGAL; GENETIC VECTORS; GLUCOSE; HUMANS; KINETICS; PEPTIDYLPROLYL ISOMERASE; PLASMIDS; PROMOTER REGIONS (GENETICS); PROTEIN FOLDING; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TRANSFORMATION, GENETIC;

ASPERGILLUS NIGER; INSECTA; MAMMALIA; TRIXIS;

EID: 0034850166     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.1156     Document Type: Article

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