Effect of agitation intensities on fungal morphology of submerged fermentation

Biotechnology and Bioengineering

Volumn 55, Issue 5, 1997, Pages 715-726

  Cui, Y Q ^a   Van Der Lans, R G J M ^a   Luyben, K C A M ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Agitation intensity; Fermentation; Fungal morphology; Hair of pellets; Hyphae; Pellets

Indexed keywords

BIOMASS; BIOREACTORS; CELL CULTURE; FUNGI; GROWTH KINETICS; HEAT LOSSES; MORPHOLOGY; SPECIFIC HEAT; TENSILE STRENGTH;

AGITATION INTENSITIES; ASPERGILLUS AWAMORI; FUNGAL MORPHOLOGY; HAIR OF PELLETS; HYPHAE; SUBMERGED FERMENTATION;

FERMENTATION;

AGITATION; ARTICLE; ASPERGILLUS AWAMORI; BIOMASS; ENERGY; FERMENTATION; FORCE; FUNGUS CULTURE; FUNGUS HYPHAE; MORPHOLOGY; MYCELIUM; NONHUMAN; SURFACE PROPERTY;

EID: 0031554874     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19970905)55:5<715::AID-BIT2>3.0.CO;2-E     Document Type: Article

References (31)

1. Ayazi Shamlou, P., Makagiansar, H. Y., Lilly, M. D., Thomas, C. R. 1994. Turbulent breakage of filamentous microorganisms in submerged culture in mechanically stirred bioreactors. Chem. Eng. Sci. 49: 2621-2631.
2. Bhavaraju, S. M., Blanch, H. W. 1976. A model for pellet breakup in fungal fermentations. J. Ferment. Technol. 54: 466-468.
3. Beverloo, W. A., Tramper, J. 1994. Intensity of microcarrier collisions in turbulent flow. Bioproc. Eng. 11: 177-184.
4. Braun, S., Vecht-Lifshitz, S. E. 1991. Mycelia morphology and metabolite production. Trends Biotechnol 9: 63-68.
5. Caulet, P. J. C., Van der Lans, R. G. J. M., Luyben, K. Ch. A. M. 1996. Hydrodynamical interactions between particles and liquid flows in biochemical applications. Chem. Eng. J. 62: 193-206.
6. Chain, E. B., Paladino S., Ugolini F., Callow D. S., van der Sluis J. 1954. A laboratory fermenter for vortex and sparger aeration. Istituto Superiore di Sanita (Eng.E.) 17: 59-85.
7. Cherry, R. S., Papoutsakis, E. T. 1988. Physical mechanisms of cell damage in microcarrier cell culture bioreactors. Biotechnol. Bioeng. 32: 1001-1014.
8. Clark D. S. 1962. Submerged citric acid fermentation of ferrocyanide-treated beet molasses: Morphology of pellets of Aspergillus niger. Can. J. Microbiol. 8: 133-136.
9. Cox, P. W., Thomas, C. R. 1992. Classification and measurement of fungal pellets by automated image analysis. Biotechnol. Bioeng. 39: 945-952.
10. Croughan, M. S., Hamel J-F. P, Wang, D. I. C. 1988. Effect of microcarrier concentration in animal cell culture. Biotechnol. Bioeng. 32: 975-982.
11. Cui, Y. Q., Van der Lans, R. G. J. M., Luyben, K. Ch. A. M. 1996. Local power uptake in gas-liquid systems with single and multiple Rushton turbines. Chem. Eng. Sci. 51: 2631-2636
12. Davies, J. T. 1972. Turbulence phenomena, p. 54. Academic Press, New York.
13. Dion, W. M., Calrilli, A., Sermonti, G., Chain, E. B. 1954. The effect of mechanical agitation on the morphology of Penicillium chrysogenum thom in stirred fermenters. Istituto Superiore di Sanita (Eng.E.) 17: 187-205.
14. Dion, W. M., Kaushal, R. 1959. The effect of mechanical agitation on the morphology of some common fungi grown in submerged culture. Istituto Superiore di Sanita (Eng.E.) 2: 357-369.
15. Edelstein, L. 1983. A model for pellet size distributions in submerged mycelial cultures. J. Theor. Biol 105: 427-452.
16. Lejeune, R. 1996. From spores to pellets: Modelling the growth and morphology of filamentous fungi. Ph. D. thesis, Vrije Universiteit Brussel, The Netherlands.
17. Kawase, Y., Moo-Yang, M. 1990. Mathematical models for design of bioreactors: Application of Kolmogoroff's theory of isotropic turbulence. Chem. Eng. J. 43: B19-B41.
18. Metz, B. 1976. From pulp to pellet. Ph.D. thesis, Delft University of Technology, The Netherlands.
19. Metz, B., De Bruijn, E. W., Van Suijdam, J. C. 1981. Method for quantitative representation of the morphology of molds. Biotechnol. Bioeng. 23: 149-162.
20. Metz, B., Kossen, N. W. F. 1977. The growth of molds in the form of pellets: Literature review. Biotechnol. Bioeng. 19: 781-799.
21. Nielsen, J., Carlsen, M. 1996. Fungal pellets, In: R. G. Willaert, G. V. Baron, and L. De Backer (eds.), Immobilised living cell systems: Modeling and experimental methods. Wiley, Chichester, UK 273-293.
22. Nielsen, J., Krabben, P. 1995. Hyphal growth and fragmentation of Penicillium chrysogenum in submerged cultures. Biotechnol. Bioeng. 46: 488-598.
23. Reichl, U., King, R., Gilles, E. D. 1992. Characterization of pellet morphology during submerged growth of Streptomyces tendae by image analysis. Biotechnol. Bioeng. 39: 164-170
24. Van Suijdam, J. C., Metz, B. 1981. Fungal pellet breakup as a function of shear in a fermenter. J. Ferment. Technol. 59: 329-333.
25. Trinci, A. P. J. 1970. Kinetics of the growth of mycelial pellets of Aspergillus nidulans. Archiv fur Mikrobiologie 73: 353-367
26. Taguchi, H., Yoshida, T., Tomita, Y., Teramoto, S. 1968. The effects of agitation on disruption of the mycelial pellets in stirred fermenters. J. Ferment. Technol. 46: 814-822.
27. Takahashi, K., Nakano, Y., Yokota, T., Nomura, T. 1993. Effect of scale on particle-impeller impact in an agitated vessel equipped with a Rushton turbine. J. Chem. Eng. Japan 26: 100-103.
28. Tsouris, C. Tavlarides, L. L. 1994. Breakage and coalescence models for drops in turbulent dispersions. AIChE J. 40: 395-406.
29. Tucker, K., Thomas, C. R. 1992. Mycelial morphology: The effect of spore inoculum level. Biotechnol. Lett. 14: 1071-1074.
30. Vecht-Lifshitz, S. E., Magdassi, S., Braun, S. 1990. Pellet formation and cellular aggregation in Streptomyces tendae. Biotechnol. Bioeng. 35: 890-896.
31. Vecht-Lifshitz, S. E., Ison, P. Andrew. 1992. Biotechnological applications of image analysis: Present and future prospects. J. Biotechnol. 23: 1-18.