메뉴 건너뛰기




Volumn 15, Issue 8, 2006, Pages 1443-1450

Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics

Author keywords

[No Author keywords available]

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; ONCOPROTEIN; PROTEIN KI RAS; PROTEIN P53; UNCLASSIFIED DRUG;

EID: 33748032054     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: 10.1158/1055-9965.EPI-06-0144     Document Type: Article
Times cited : (34)

References (75)
  • 2
    • 0016074363 scopus 로고
    • President's address. The polyp-cancer sequence in the large bowel
    • Morson B. President's address. The polyp-cancer sequence in the large bowel. Proc R Soc Med 1974;67:451-7.
    • (1974) Proc R Soc Med , vol.67 , pp. 451-457
    • Morson, B.1
  • 4
    • 0026781103 scopus 로고
    • Progressing toward a molecular description of colorectal cancer development
    • Fearon ER, Jones PA. Progressing toward a molecular description of colorectal cancer development. FASEB J 1992;6:2783-90.
    • (1992) FASEB J , vol.6 , pp. 2783-2790
    • Fearon, E.R.1    Jones, P.A.2
  • 5
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-67.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 6
    • 0027145633 scopus 로고
    • Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer
    • Leach FS, Nicolaides NC, Papadopoulos N, et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer. Cell 1993;75:1215-25.
    • (1993) Cell , vol.75 , pp. 1215-1225
    • Leach, F.S.1    Nicolaides, N.C.2    Papadopoulos, N.3
  • 7
    • 0034830884 scopus 로고    scopus 로고
    • Analysis of K-ras, APC, and β-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis
    • Takayama T, Ohi M, Hayashi T, et al. Analysis of K-ras, APC, and β-catenin in aberrant crypt foci in sporadic adenoma, cancer, and familial adenomatous polyposis. Gastroenterology 2001;121:599-611.
    • (2001) Gastroenterology , vol.121 , pp. 599-611
    • Takayama, T.1    Ohi, M.2    Hayashi, T.3
  • 8
    • 0034102422 scopus 로고    scopus 로고
    • APC mutations are sufficient for the growth of early colorectal adenomas
    • Lamlum H, Papadopoulou A, Ilyas M, et al. APC mutations are sufficient for the growth of early colorectal adenomas. Proc Natl Acad Sci U S A 2000;97:2225-8.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2225-2228
    • Lamlum, H.1    Papadopoulou, A.2    Ilyas, M.3
  • 9
    • 0038731306 scopus 로고    scopus 로고
    • K-ras oncogene mutations in sporadic colorectal cancer in the Netherlands Cohort Study
    • Brink M, de Goeij AF, Weijenberg MP, et al. K-ras oncogene mutations in sporadic colorectal cancer in the Netherlands Cohort Study. Carcinogenesis 2003;24:703-10.
    • (2003) Carcinogenesis , vol.24 , pp. 703-710
    • Brink, M.1    De Goeij, A.F.2    Weijenberg, M.P.3
  • 10
    • 0034910649 scopus 로고    scopus 로고
    • Ki-ras proto-oncogene mutations in sporadic colorectal adenomas: Relationship to histologic and clinical characteristics
    • Maltzman T, Knoll K, Martinez ME, et al. Ki-ras proto-oncogene mutations in sporadic colorectal adenomas: relationship to histologic and clinical characteristics. Gastroenterology 2001;121:302-9.
    • (2001) Gastroenterology , vol.121 , pp. 302-309
    • Maltzman, T.1    Knoll, K.2    Martinez, M.E.3
  • 11
    • 0030043831 scopus 로고    scopus 로고
    • Prognostic value of TP53 and K-ras-2 mutational analysis in stage III carcinoma of the colon
    • Pricolo VE, Finkelstein SD, Wu TT, et al. Prognostic value of TP53 and K-ras-2 mutational analysis in stage III carcinoma of the colon. Am J Surg 1996;171:41-6.
    • (1996) Am J Surg , vol.171 , pp. 41-46
    • Pricolo, V.E.1    Finkelstein, S.D.2    Wu, T.T.3
  • 12
    • 0032521205 scopus 로고    scopus 로고
    • Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: A Southwest Oncology Group study
    • Ahnen DJ, Feigl P, Quan G, et al. Ki-ras mutation and p53 overexpression predict the clinical behavior of colorectal cancer: a Southwest Oncology Group study. Cancer Res 1998;58:1149-58.
    • (1998) Cancer Res , vol.58 , pp. 1149-1158
    • Ahnen, D.J.1    Feigl, P.2    Quan, G.3
  • 13
    • 0030499353 scopus 로고    scopus 로고
    • K-ras gene mutation is a useful predictor of the survival of early stage colorectal cancers
    • Lee JC, Wang ST, Lai MD, Lin YJ, Yang HB. K-ras gene mutation is a useful predictor of the survival of early stage colorectal cancers. Anticancer Res 1996;16:3839-44.
    • (1996) Anticancer Res , vol.16 , pp. 3839-3844
    • Lee, J.C.1    Wang, S.T.2    Lai, M.D.3    Lin, Y.J.4    Yang, H.B.5
  • 14
    • 0032033144 scopus 로고    scopus 로고
    • Ki-ras mutations and prognosis in colorectal cancer
    • Kressner U, Bjorheim J, Westring S, et al. Ki-ras mutations and prognosis in colorectal cancer. Eur J Cancer 1998;34:518-21.
    • (1998) Eur J Cancer , vol.34 , pp. 518-521
    • Kressner, U.1    Bjorheim, J.2    Westring, S.3
  • 15
    • 0033021390 scopus 로고    scopus 로고
    • Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas
    • Rashid A, Zahurak M, Goodman SN, Hamilton SR. Genetic epidemiology of mutated K-ras proto-oncogene, altered suppressor genes, and microsatellite instability in colorectal adenomas. Gut 1999;44:826-33.
    • (1999) Gut , vol.44 , pp. 826-833
    • Rashid, A.1    Zahurak, M.2    Goodman, S.N.3    Hamilton, S.R.4
  • 18
    • 0023748414 scopus 로고
    • Genetic alterations during colorectal-tumor development
    • Vogelstein B, Fearon ER, Hamilton SR, et al. Genetic alterations during colorectal-tumor development. N Engl J Med 1988;319:525-32.
    • (1988) N Engl J Med , vol.319 , pp. 525-532
    • Vogelstein, B.1    Fearon, E.R.2    Hamilton, S.R.3
  • 19
    • 0036142361 scopus 로고    scopus 로고
    • Detection of genetic alterations in the p53 suppressor gene and the K-ras oncogene among different grades of dysplasia in patients with colorectal adenomas
    • Hosaka S, Aoki Y, Akamatsu T, Nakamura N, Hosaka N, Kiyosawa K. Detection of genetic alterations in the p53 suppressor gene and the K-ras oncogene among different grades of dysplasia in patients with colorectal adenomas. Cancer 2002;94:219-27.
    • (2002) Cancer , vol.94 , pp. 219-227
    • Hosaka, S.1    Aoki, Y.2    Akamatsu, T.3    Nakamura, N.4    Hosaka, N.5    Kiyosawa, K.6
  • 21
    • 0037047057 scopus 로고    scopus 로고
    • Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer
    • Smith G, Carey FA, Beattie J, et al. Mutations in APC, Kirsten-ras, and p53-alternative genetic pathways to colorectal cancer. Proc Natl Acad Sci U S A 2002;99:9433-8.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 9433-9438
    • Smith, G.1    Carey, F.A.2    Beattie, J.3
  • 22
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • Bos JL, Fearon ER, Hamilton SR, et al. Prevalence of ras gene mutations in human colorectal cancers. Nature 1987;327:293-7.
    • (1987) Nature , vol.327 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2    Hamilton, S.R.3
  • 23
    • 0023898932 scopus 로고
    • The ras gene family and human carcinogenesis
    • Bos JL. The ras gene family and human carcinogenesis. Mutat Res 1988;195:255-71.
    • (1988) Mutat Res , vol.195 , pp. 255-271
    • Bos, J.L.1
  • 24
    • 0028053024 scopus 로고
    • K-ras mutation in colorectal cancer: Relations to patient age, sex and tumour location
    • Breivik J, Meling GI, Spurkland A, Rognum TO, Gaudernack G. K-ras mutation in colorectal cancer: relations to patient age, sex and tumour location. Br J Cancer 1994;69:367-71.
    • (1994) Br J Cancer , vol.69 , pp. 367-371
    • Breivik, J.1    Meling, G.I.2    Spurkland, A.3    Rognum, T.O.4    Gaudernack, G.5
  • 26
    • 0027509209 scopus 로고
    • Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer
    • Bell SM, Scott N, Cross D, et al. Prognostic value of p53 overexpression and c-Ki-ras gene mutations in colorectal cancer. Gastroenterology 1993;104:57-64.
    • (1993) Gastroenterology , vol.104 , pp. 57-64
    • Bell, S.M.1    Scott, N.2    Cross, D.3
  • 28
    • 0030920821 scopus 로고    scopus 로고
    • K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients
    • Zhu D, Keohavong P, Finkelstein SD, et al. K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients. Cancer Res 1997;57:2485-92.
    • (1997) Cancer Res , vol.57 , pp. 2485-2492
    • Zhu, D.1    Keohavong, P.2    Finkelstein, S.D.3
  • 29
    • 0026528846 scopus 로고
    • Getting a handle on Ras activity
    • Hoffman M. Getting a handle on Ras activity. Science 1992;255:159.
    • (1992) Science , vol.255 , pp. 159
    • Hoffman, M.1
  • 30
    • 0026695813 scopus 로고
    • Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients
    • Kikuchi-Yanoshita R, Konishi M, Ito S, et al. Genetic changes of both p53 alleles associated with the conversion from colorectal adenoma to early carcinoma in familial adenomatous polyposis and non-familial adenomatous polyposis patients. Cancer Res 1992;52:3965-71.
    • (1992) Cancer Res , vol.52 , pp. 3965-3971
    • Kikuchi-Yanoshita, R.1    Konishi, M.2    Ito, S.3
  • 31
    • 0027212026 scopus 로고
    • Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia
    • Urosevic N, Krtolica K, Skaro-Milic A, Knezevic-Usaj S, Dujic A. Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia. Int J Cancer 1993;54:249-54.
    • (1993) Int J Cancer , vol.54 , pp. 249-254
    • Urosevic, N.1    Krtolica, K.2    Skaro-Milic, A.3    Knezevic-Usaj, S.4    Dujic, A.5
  • 32
    • 0035444798 scopus 로고    scopus 로고
    • Kirsten ras mutations in patients with colorectal cancer: The 'RASCAL II' study
    • Andreyev HJ, Norman AR, Cunningham D, et al. Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer 2001;85:692-6.
    • (2001) Br J Cancer , vol.85 , pp. 692-696
    • Andreyev, H.J.1    Norman, A.R.2    Cunningham, D.3
  • 33
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-31.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 34
    • 0027201180 scopus 로고
    • Genetic events in sporadic colorectal adenomas: K-ras and p53 heterozygous mutations are not sufficient for malignant progression
    • De Benedetti L, Varesco L, Pellegata NS, et al. Genetic events in sporadic colorectal adenomas: K-ras and p53 heterozygous mutations are not sufficient for malignant progression. Anticancer Res 1993;13:667-70.
    • (1993) Anticancer Res , vol.13 , pp. 667-670
    • De Benedetti, L.1    Varesco, L.2    Pellegata, N.S.3
  • 35
    • 0028345139 scopus 로고
    • Overexpression of p53 protein and proliferative activity in colorectal adenoma
    • Yamaguchi A, Makimoto K, Goi T, et al. Overexpression of p53 protein and proliferative activity in colorectal adenoma. Oncology 1994;51:224-7.
    • (1994) Oncology , vol.51 , pp. 224-227
    • Yamaguchi, A.1    Makimoto, K.2    Goi, T.3
  • 39
    • 0026040390 scopus 로고
    • Loss of heterozygosity of p53 gene and p53 protein expression in human colorectal carcinomas
    • Campo E, de la Calle-Martin O, Miquel R, et al. Loss of heterozygosity of p53 gene and p53 protein expression in human colorectal carcinomas. Cancer Res 1991;51:4436-42.
    • (1991) Cancer Res , vol.51 , pp. 4436-4442
    • Campo, E.1    De La Calle-Martin, O.2    Miquel, R.3
  • 40
    • 0028151812 scopus 로고
    • Immunohistochemical analysis of p53 overexpression in human colonic tumors
    • Darmon E, Cleary KR, Wargovich MJ. Immunohistochemical analysis of p53 overexpression in human colonic tumors. Cancer Detect Prev 1994;18:187-95.
    • (1994) Cancer Detect Prev , vol.18 , pp. 187-195
    • Darmon, E.1    Cleary, K.R.2    Wargovich, M.J.3
  • 41
    • 0342657814 scopus 로고    scopus 로고
    • Lack of effect of a high-fiber cereal supplement on the recurrence of colorectal adenomas
    • Phoenix Colon Cancer Prevention Physicians' Network
    • Alberts DS, Martinez ME, Roe DJ, et al. Lack of effect of a high-fiber cereal supplement on the recurrence of colorectal adenomas. Phoenix Colon Cancer Prevention Physicians' Network. N Engl J Med 2000;342:1156-62.
    • (2000) N Engl J Med , vol.342 , pp. 1156-1162
    • Alberts, D.S.1    Martinez, M.E.2    Roe, D.J.3
  • 42
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
    • Baas IO, Mulder JW, Offerhaus GJ, Vogelstein B, Hamilton SR. An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms. J Pathol 1994;172:5-12.
    • (1994) J Pathol , vol.172 , pp. 5-12
    • Baas, I.O.1    Mulder, J.W.2    Offerhaus, G.J.3    Vogelstein, B.4    Hamilton, S.R.5
  • 43
    • 0344423822 scopus 로고    scopus 로고
    • Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas
    • Martinez ME, Maltzman T, Marshall JR, et al. Risk factors for Ki-ras protooncogene mutation in sporadic colorectal adenomas. Cancer Res 1999;59:5181-5.
    • (1999) Cancer Res , vol.59 , pp. 5181-5185
    • Martinez, M.E.1    Maltzman, T.2    Marshall, J.R.3
  • 45
    • 0030980880 scopus 로고    scopus 로고
    • Genetic heterogeneity in sporadic colorectal adenomas
    • Saraga E, Bautista D, Dorta G, et al. Genetic heterogeneity in sporadic colorectal adenomas. J Pathol 1997;181:281-6.
    • (1997) J Pathol , vol.181 , pp. 281-286
    • Saraga, E.1    Bautista, D.2    Dorta, G.3
  • 46
    • 8944243540 scopus 로고    scopus 로고
    • K-ras mutations and HLA-DR expression in large bowel adenomas
    • Norheim Andersen S, Breivik J, Lovig T, et al. K-ras mutations and HLA-DR expression in large bowel adenomas. Br J Cancer 1996;74:99-108.
    • (1996) Br J Cancer , vol.74 , pp. 99-108
    • Norheim Andersen, S.1    Breivik, J.2    Lovig, T.3
  • 47
    • 0029859569 scopus 로고    scopus 로고
    • Effect of K-ras mutation on morphogenesis of colorectal adenomas and early cancers: Relationship to distribution of proliferating cells
    • Kobayashi M, Watanabe H, Ajioka Y, Honma T, Asakura H. Effect of K-ras mutation on morphogenesis of colorectal adenomas and early cancers: relationship to distribution of proliferating cells. Hum Pathol 1996;27:1042-9.
    • (1996) Hum Pathol , vol.27 , pp. 1042-1049
    • Kobayashi, M.1    Watanabe, H.2    Ajioka, Y.3    Honma, T.4    Asakura, H.5
  • 48
    • 0030470733 scopus 로고    scopus 로고
    • Ki-ras mutations in adenomas: A characteristic of cancer-bearing colorectal mucosa
    • Morris RG, Curb's LJ, Romanowski P, et al. Ki-ras mutations in adenomas: a characteristic of cancer-bearing colorectal mucosa. J Pathol 1996;180:357-63.
    • (1996) J Pathol , vol.180 , pp. 357-363
    • Morris, R.G.1    Curb'S, L.J.2    Romanowski, P.3
  • 49
    • 0029040928 scopus 로고
    • K-ras gene mutation related to histological atypias in human colorectal adenomas
    • Ajiki T, Fujimori T, Ikehara H, Saitoh Y, Maeda S. K-ras gene mutation related to histological atypias in human colorectal adenomas. Biotech Histochem 1995;70:90-4.
    • (1995) Biotech Histochem , vol.70 , pp. 90-94
    • Ajiki, T.1    Fujimori, T.2    Ikehara, H.3    Saitoh, Y.4    Maeda, S.5
  • 50
    • 0034076511 scopus 로고    scopus 로고
    • Activation of c-K-ras mutations in human gastrointestinal tumors
    • Arber N, Shapira I, Ratan J, et al. Activation of c-K-ras mutations in human gastrointestinal tumors. Gastroenterology 2000;118:1045-50.
    • (2000) Gastroenterology , vol.118 , pp. 1045-1050
    • Arber, N.1    Shapira, I.2    Ratan, J.3
  • 51
    • 8044238349 scopus 로고    scopus 로고
    • A detailed analysis of the role of K-ras gene mutation in the progression of colorectal adenoma
    • Ohnishi T, Tomita N, Monden T, et al. A detailed analysis of the role of K-ras gene mutation in the progression of colorectal adenoma. Br J Cancer 1997;75:341-7.
    • (1997) Br J Cancer , vol.75 , pp. 341-347
    • Ohnishi, T.1    Tomita, N.2    Monden, T.3
  • 52
    • 0029129117 scopus 로고
    • Adenoma-carcinoma sequence of colorectum. Prevalence of K-ras gene mutation in adenomas with increasing degree of dysplasia and aneuploidy
    • Ranaldi R, Gioacchini AM, Manzin A, Clementi M, Paolucci S, Bearzi I. Adenoma-carcinoma sequence of colorectum. Prevalence of K-ras gene mutation in adenomas with increasing degree of dysplasia and aneuploidy. Diagn Mol Pathol 1995;4:198-202.
    • (1995) Diagn Mol Pathol , vol.4 , pp. 198-202
    • Ranaldi, R.1    Gioacchini, A.M.2    Manzin, A.3    Clementi, M.4    Paolucci, S.5    Bearzi, I.6
  • 53
    • 0028066833 scopus 로고
    • A frequent alteration of p53 gene in carcinoma in adenoma of colon
    • Ohue M, Tomita N, Monden T, et al. A frequent alteration of p53 gene in carcinoma in adenoma of colon. Cancer Res 1994;54:4798-804.
    • (1994) Cancer Res , vol.54 , pp. 4798-4804
    • Ohue, M.1    Tomita, N.2    Monden, T.3
  • 54
    • 0028265866 scopus 로고
    • Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas
    • Yamagata S, Muto T, Uchida Y, et al. Lower incidence of K-ras codon 12 mutation in flat colorectal adenomas than in polypoid adenomas. Jpn J Cancer Res 1994;85:147-51.
    • (1994) Jpn J Cancer Res , vol.85 , pp. 147-151
    • Yamagata, S.1    Muto, T.2    Uchida, Y.3
  • 57
    • 0030846208 scopus 로고    scopus 로고
    • Clinical investigation of colorectal cancer detected by follow-up colonoscopy after endoscopic polypectomy
    • Nozaki R, Takagi K, Takano M, Miyata M. Clinical investigation of colorectal cancer detected by follow-up colonoscopy after endoscopic polypectomy. Dis Colon Rectum 1997;40:S16-22.
    • (1997) Dis Colon Rectum , vol.40
    • Nozaki, R.1    Takagi, K.2    Takano, M.3    Miyata, M.4
  • 58
    • 0026089391 scopus 로고
    • Higher frequency of point mutations in the c-K-ras 2 gene in human colorectal adenomas with severe atypia than in carcinomas
    • Ando M, Maruyama M, Oto M, Takemura K, Endo M, Yuasa Y. Higher frequency of point mutations in the c-K-ras 2 gene in human colorectal adenomas with severe atypia than in carcinomas. Jpn J Cancer Res 1991;82:245-9.
    • (1991) Jpn J Cancer Res , vol.82 , pp. 245-249
    • Ando, M.1    Maruyama, M.2    Oto, M.3    Takemura, K.4    Endo, M.5    Yuasa, Y.6
  • 59
    • 0035500820 scopus 로고    scopus 로고
    • Lifestyle factors and Ki-ras mutations in colon cancer tumors
    • Slattery ML, Anderson K, Curtin K, et al. Lifestyle factors and Ki-ras mutations in colon cancer tumors. Mutat Res 2001;483:73-81.
    • (2001) Mutat Res , vol.483 , pp. 73-81
    • Slattery, M.L.1    Anderson, K.2    Curtin, K.3
  • 60
    • 0034026701 scopus 로고    scopus 로고
    • p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer
    • Bouzourene H, Gervaz P, Cerottini JP, et al. p53 and Ki-ras as prognostic factors for Dukes' stage B colorectal cancer. Eur J Cancer 2000;36:1008-15.
    • (2000) Eur J Cancer , vol.36 , pp. 1008-1015
    • Bouzourene, H.1    Gervaz, P.2    Cerottini, J.P.3
  • 61
    • 0028854853 scopus 로고
    • Polypoid growth and K-ras codon 12 mutation in colorectal cancer
    • Yamagata S, Muto T, Uchida Y, et al. Polypoid growth and K-ras codon 12 mutation in colorectal cancer. Cancer 1995;75:953-7.
    • (1995) Cancer , vol.75 , pp. 953-957
    • Yamagata, S.1    Muto, T.2    Uchida, Y.3
  • 63
    • 25144518262 scopus 로고    scopus 로고
    • MGMT promoter methylation and field defect in sporadic colorectal cancer
    • Shen L, Kondo Y, Rosner GL, et al. MGMT promoter methylation and field defect in sporadic colorectal cancer. J Natl Cancer Inst 2005;97:1330-8.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1330-1338
    • Shen, L.1    Kondo, Y.2    Rosner, G.L.3
  • 64
    • 0032883992 scopus 로고    scopus 로고
    • A relationship between K-ras gene mutations and some clinical and histologic variables in patients with primary colorectal carcinoma
    • Beranek M, Bures J, Palicka V, Jandik P, Langr F, Nejedla E. A relationship between K-ras gene mutations and some clinical and histologic variables in patients with primary colorectal carcinoma. Clin Chem Lab Med 1999;37:723-7.
    • (1999) Clin Chem Lab Med , vol.37 , pp. 723-727
    • Beranek, M.1    Bures, J.2    Palicka, V.3    Jandik, P.4    Langr, F.5    Nejedla, E.6
  • 65
    • 0033916701 scopus 로고    scopus 로고
    • K-ras mutations, rectal crypt cells proliferation, and meat consumption in patients with left-sided colorectal carcinoma
    • O'Brien H, Matthew JA, Gee JM, et al. K-ras mutations, rectal crypt cells proliferation, and meat consumption in patients with left-sided colorectal carcinoma. Eur J Cancer Prev 2000;9:41-7.
    • (2000) Eur J Cancer Prev , vol.9 , pp. 41-47
    • O'Brien, H.1    Matthew, J.A.2    Gee, J.M.3
  • 66
    • 0034959553 scopus 로고    scopus 로고
    • Short-chain fatty acids and human colonic function: Roles of resistant starch and nonstarch polysaccharides
    • Topping DL, Clifton PM. Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev 2001;81:1031-64.
    • (2001) Physiol Rev , vol.81 , pp. 1031-1064
    • Topping, D.L.1    Clifton, P.M.2
  • 67
    • 0034056019 scopus 로고    scopus 로고
    • Nutrition and dietary carcinogens
    • Sugimura T. Nutrition and dietary carcinogens. Carcinogenesis 2000;21:387-95.
    • (2000) Carcinogenesis , vol.21 , pp. 387-395
    • Sugimura, T.1
  • 68
    • 0032105420 scopus 로고    scopus 로고
    • P53 protein immunohistochemical expression in colonic adenomas with and without associated carcinoma
    • Saleh HA, Aburashed A, Bober P, Tabaczka P. P53 protein immunohistochemical expression in colonic adenomas with and without associated carcinoma. Am J Gastroenterol 1998;93:980-4.
    • (1998) Am J Gastroenterol , vol.93 , pp. 980-984
    • Saleh, H.A.1    Aburashed, A.2    Bober, P.3    Tabaczka, P.4
  • 69
    • 0026664077 scopus 로고
    • Expression of p53 and 17p allelic loss in colorectal carcinoma
    • Cunningham J, Lust JA, Schaid DJ, et al. Expression of p53 and 17p allelic loss in colorectal carcinoma. Cancer Res 1992;52:1974-80.
    • (1992) Cancer Res , vol.52 , pp. 1974-1980
    • Cunningham, J.1    Lust, J.A.2    Schaid, D.J.3
  • 70
    • 0031825506 scopus 로고    scopus 로고
    • DNA flow cytometry, p53 levels and proliferative cell nuclear antigen in human colon dysplastic, precancerous and cancerous tissues
    • Barletta A, Marzullo F, Pellecchia A, et al. DNA flow cytometry, p53 levels and proliferative cell nuclear antigen in human colon dysplastic, precancerous and cancerous tissues. Anticancer Res 1998;18:1677-82.
    • (1998) Anticancer Res , vol.18 , pp. 1677-1682
    • Barletta, A.1    Marzullo, F.2    Pellecchia, A.3
  • 71
    • 0026555153 scopus 로고
    • Immunohistochemical study of p53 expression in microwave-fixed, paraffin-embedded sections of colorectal carcinoma and adenoma
    • Kawasaki Y, Monden T, Morimoto H, et al. Immunohistochemical study of p53 expression in microwave-fixed, paraffin-embedded sections of colorectal carcinoma and adenoma. Am J Clin Pathol 1992;97:244-9.
    • (1992) Am J Clin Pathol , vol.97 , pp. 244-249
    • Kawasaki, Y.1    Monden, T.2    Morimoto, H.3
  • 72
    • 0028901054 scopus 로고
    • p53 gene mutations in early colorectal carcinoma. De novo vs. adenoma-carcinoma sequence
    • Hasegawa H, Ueda M, Furukawa K, et al. p53 gene mutations in early colorectal carcinoma. De novo vs. adenoma-carcinoma sequence. Int J Cancer 1995;64:47-51.
    • (1995) Int J Cancer , vol.64 , pp. 47-51
    • Hasegawa, H.1    Ueda, M.2    Furukawa, K.3
  • 73
    • 0037138441 scopus 로고    scopus 로고
    • Associations between family history of colorectal cancer and genetic alterations in tumors
    • Slattery ML, Curtin K, Schaffer D, Anderson K, Samowitz W. Associations between family history of colorectal cancer and genetic alterations in tumors. Int J Cancer 2002;97:823-7.
    • (2002) Int J Cancer , vol.97 , pp. 823-827
    • Slattery, M.L.1    Curtin, K.2    Schaffer, D.3    Anderson, K.4    Samowitz, W.5
  • 74
    • 33846298396 scopus 로고    scopus 로고
    • Familial and nutritional risk factors for p53 overexpression in colorectal cancer
    • Freedman AN, Michalek AM, Marshall JR, et al. Familial and nutritional risk factors for p53 overexpression in colorectal cancer. Cancer Epidemiol Biomarkers Prev 1996;5:285-91.
    • (1996) Cancer Epidemiol Biomarkers Prev , vol.5 , pp. 285-291
    • Freedman, A.N.1    Michalek, A.M.2    Marshall, J.R.3
  • 75
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993;260:816-9.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.