APC mutations are sufficient for the growth of early colorectal adenomas

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 5, 2000, Pages 2225-2228

  Lamlum, Hanan ^a   Papadopoulou, Angeliki ^a   Ilyas, Mohammad ^b   Rowan, Andrew ^a   Gillet, Cheryl ^c   Hanby, Andrew ^c   Talbot, Ian ^d   Bodmer, Walter ^b   Tomlinson, Ian ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^c GUY S HOSPITAL   (United Kingdom)

^d Acad Department of Histopathology   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; BETA CATENIN;

ADENOMA; ALLELE; ARTICLE; CARCINOGENESIS; CHROMOSOME 5Q; CHROMOSOME LOSS; COLORECTAL TUMOR; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; MICROSATELLITE INSTABILITY; ONCOGENE K RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; ADENOMATOUS POLYPOSIS COLI PROTEIN; CYTOSKELETAL PROTEINS; GERM-LINE MUTATION; HUMANS;

EID: 0034102422     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.040564697     Document Type: Article

References (21)

1. Miyaki, M., Tanaka, K., Kikuchi Yanoshita, R., Muraoka, M. & Konishi, M. (1995) Crit. Rev. Oncol. Hematol. 19, 1-31.
2. Lamlum, H., Ilyas, M., Rowan, A., Clark, S., Johnson, V., Bell, J., Frayling, I., Efstathiou, J., Pack, K., Payne, S., et al (1999) Nat. Med. 5, 1071-1075.
3. Kinzler, K. & Vogelstein, B. (1997) Cell 87, 159-170.
4. Morin, P. J., Sparks, A. B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B. & Kinzler, K. W. (1997) Science 275, 1787-1790.
5. Ilyas, M., Tomlinson, I. P. M., Rowan, A., Pignatelli, M. & Bodmer, W. F. (1997) Proc. Natl. Acad. Sci. USA 94, 10330-10334.
6. Bardi, G., Johansson, B., Pandis, N., Bakjensen, E., Orndal, C., Heim, S., Mandahl, N., Andren-Sandberg, A. & Mitelman, F. (1993) Cancer 71, 306-314.
7. Tanaka, K., Yanoshita, R., Konishi, M., Oshimura, M., Maeda, Y., Mori, T. & Miyaki, M. (1993) Oncogene 8, 2253-2258.
8. Lothe, R. A., Andersen, S. N., Hofstad, B., Meling, G. I., Peltomaki, P., Heim, S., Brogger, A., Vatn, M., Rognum, T. O. & Borresen, A. L. (1995) Genes Chromosomes Cancer 14, 182-188.
9. Praml, C., Finke, L. H., Herfarth, C., Schlag, P., Schwab, M. & Amler, L. (1995) Oncogene 11, 1357-1362.
10. Span, M., Moerkerk, P., De Goeij, A. & Arends, J. (1996) Int. J. Cancer 69, 241-245.
11. Beck, N. E., Tomlinson, I. P. M., Homfray, T. F. R., Frayling, I. M., Hodgson, S. V. & Bodmer, W. F. (1997) Gut 41, 335-338.
12. Hao, X., Palazzo, J. P., Ilyas, M., Tomlinson, I. & Talbot, I. C. (1997) Anticancer Res. 17, 2241-2247.
13. Miyaki, M., Konishsi, M., Kikuchi-Yanoshita, R., Enomoto, M., Igari, T., Tanaka, K., Muraoka, M., Takahashi, H., Amada, Y., Fukayama, M., et al. (1994) Cancer Res. 54, 3011-3020.
14. Spirio, L., Samowitz, W., Robertson, J., Robertson, M., Burt, R., Leppert, M. & White, R. (1998) Nat. Genet. 20, 385-388.
15. Minamoto, T., Yamashita, N., Ochiai, A., Mai, M., Sugimura, T., Ronai, Z. & Esumi, H. (1995) Cancer 75, Suppl. 6, 1520-1526.
16. Smith, A. J., Stern, H. S., Penner, M., Hay, K., Mitri, A., Bapat, B. V. & Gallinger, S. (1994) Cancer Res. 54, 5527-5530.
17. Samowitz, W., Powers, M., Spirio, L., Nollet, F., van Roy, F. & Slattery, M. (1999) Cancer Res. 59, 1442-1444.
18. Tomlinson, I., Novelli, M. & Bodmer, W. (1996) Proc. Natl. Acad. Sci. USA 93, 14800-14803.
19. Homfray, T. F. R., Cottrell, S. E., Ilyas, M., Rowan, A., Talbot, I. C., Bodmer, W. F. & Tomlinson, I. P. M. (1998) Hum. Mutat. 11, 114-120.
20. Ogunbiyi, O., Goodfellow, P., Gagliardi, G., Swanson, P., Birnbaum, E., Fleshman, J., Kodner, I. J. & Moley, J. F. (1997) Gastroenterohgy 113, 761-766.
21. Bodmer, W. (1999) Cytogenet. Cell Genet. 86, 99-104.