Inhibition of the human liver microsomal and human cytochrome P450 1A2 and 3A4 metabolism of estradiol by deployment-related and other chemicals

Drug Metabolism and Disposition

Volumn 34, Issue 9, 2006, Pages 1606-1614

  Usmani, Khawja A ^a   Cho, Taehyeon M ^b   Rose, Randy L ^b   Hodgson, Ernest ^b  

^a ARENA PHARMACEUTICALS   (United States)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A2; CYTOCHROME P450 3A4; ESTRADIOL;

ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; HUMAN; HUMAN CELL; INCUBATION TIME; KINETICS; LIVER MICROSOME; PHENOTYPE; PRIORITY JOURNAL;

CARBARYL; CHLORPYRIFOS; CHOLINESTERASE INHIBITORS; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; FEMALE; FONOFOS; HUMANS; KINETICS; LIVER; MALE; MICROSOMES, LIVER; MILITARY MEDICINE; RECOMBINANT PROTEINS;

EID: 33747816449     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.106.010439     Document Type: Article

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