Locomotor and sensorimotor performance deficit in rats following exposure to pyridostigmine bromide, DEET, and permethrin, alone and in combination

Toxicological Sciences

Volumn 60, Issue 2, 2001, Pages 305-314

  Abou Donia, Mohammed B ^a   Goldstein, Larry B ^a,b   Jones, Katherine H ^a,b   Abdel Rahman, Ali A ^a   Damodaran, Tirupapuliyur V ^a   Dechkovskaia, Anjelika M ^a   Bullman, Sarah L ^a,b   Amir, Belal E ^a   Khan, Wasiuddin A ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DURHAM VA MEDICAL CENTER   (United States)

Author keywords

CNS; Combined exposure; DEET; Permethrin; Persian Gulf War; Pyridostigmine bromide; Sensorimotor

Indexed keywords

ACETYLCHOLINESTERASE; BRAIN ENZYME; CHOLINE ACETYLTRANSFERASE; CHOLINESTERASE; DIETHYLTOLUAMIDE; MUSCARINIC RECEPTOR; PERMETHRIN; PYRIDOSTIGMINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTHRALGIA; ARTICLE; ATAXIA; BRAIN CORTEX; BRAIN STEM; CEREBELLUM; CHOLINERGIC SYSTEM; CHRONIC FATIGUE SYNDROME; COGNITION; CONCENTRATION LOSS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INHIBITION; EXPOSURE; LIGAND BINDING; LOCOMOTION; MALE; MESENCEPHALON; MYALGIA; NONHUMAN; PERSIAN GULF SYNDROME; RAT; RAT STRAIN; SCORING SYSTEM; SENSORIMOTOR FUNCTION; SOLDIER; SYMPTOM; TIME; WALKING;

ACETYLCHOLINESTERASE; ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ANIMALS; BEHAVIOR, ANIMAL; BRAIN; BUTYRYLCHOLINESTERASE; CHOLINE O-ACETYLTRANSFERASE; DEET; DRUG INTERACTIONS; MALE; PERMETHRIN; PSYCHOMOTOR PERFORMANCE; PYRETHRINS; PYRIDOSTIGMINE BROMIDE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MUSCARINIC M2; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC;

ANIMALIA; ATAXIA;

EID: 0035074782     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/60.2.305     Document Type: Article

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