Huntingtin phosphorylation sites mapped by mass spectrometry: Modulation of cleavage and toxicity

Journal of Biological Chemistry

Volumn 281, Issue 33, 2006, Pages 23686-23697

  Schilling, Birgit ^a   Gafni, Juliette ^a   Torcassi, Cameron ^a   Cong, Xin ^a   Row, Richard H ^a   LaFevre Bernt, Michelle A ^a   Cusack, Michael P ^a   Ratovitski, Tamara ^b   Hirschhorn, Ricky ^b,c   Ross, Christopher A ^b   Gibson, Bradford W ^a,d   Ellerby, Lisa M ^a,e  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOOD COLLEGE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; AMINO ACIDS; CELL CULTURE; MASS SPECTROMETRY; NEUROLOGY; TOXIC MATERIALS;

CELL CULTURE MODELS; CYTOTOXICITY; PATHOGENESIS; PHOSPHORYLATION;

PROTEINS;

ALKALINE PHOSPHATASE; ASPARTIC ACID; CALPAIN; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 5; HUNTINGTIN; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; PROTEINASE; SERINE;

ANIMAL CELL; ARTICLE; CELL STRAIN; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYTOTOXICITY; GENE MAPPING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; TANDEM MASS SPECTROMETRY; WESTERN BLOTTING;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HUNTINGTON DISEASE; HYDROLYSIS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PC12 CELLS; PEPTIDE HYDROLASES; PHOSPHOPEPTIDES; PHOSPHORYLATION; PROTEIN INTERACTION MAPPING; RATS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 33747633422     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M513507200     Document Type: Article

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