Cleavage of atrophin-1 at caspase site aspartic acid 109 modulates cytotoxicity

Journal of Biological Chemistry

Volumn 274, Issue 13, 1999, Pages 8730-8736

  Ellerby, Lisa M ^a   Andrusiak, Rebecca L ^a   Wellington, Cheryl L ^b   Hackam, Abigail S ^b   Propp, Stephanie S ^a   Wood, Jonathan D ^c   Sharp, Alan H ^c   Margolis, Russell L ^c   Ross, Christopher A ^c   Salvesen, Guy S ^a   Hayden, Michael R ^b   Bredesen, Dale E ^a,d  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CASPASE;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DENTATORUBROPALLIDOLUYSIAN ATROPHY; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME SUBSTRATE; GENE CONSTRUCT; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; APOPTOSIS; ATROPHY; CASPASE 3; CASPASES; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; NERVE TISSUE PROTEINS; PEPTIDES; PROTEIN CONFORMATION; TAMOXIFEN; TRANSFECTION; TRINUCLEOTIDE REPEATS;

EID: 0033605746     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.13.8730     Document Type: Article

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