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Volumn 3, Issue 2, 2006, Pages 167-174

Nervous system cancer models: Medulloblastoma

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; BUTYRIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLOPAMINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; HISTONE DEACETYLASE INHIBITOR; ISOTRETINOIN; MONOCLONAL ANTIBODY; MYC PROTEIN; N [N (3,5 DIFLUOROPHENACETYL)ALANYL]PHENYLGLYCINE TERT BUTYL ESTER; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NOTCH RECEPTOR; ONCOPROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN INHIBITOR; PROTEIN KINASE B; PROTEIN P53; PROTEIN PATCHED 1; RETINOBLASTOMA PROTEIN; RETINOIC ACID; RETINOID; SOMATOMEDIN B; SOMATOMEDIN C RECEPTOR; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR OTX2; TRICHOSTATIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG; VORINOSTAT;

EID: 33747439435     PISSN: 17406757     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddmod.2006.05.007     Document Type: Review
Times cited : (2)

References (32)
  • 1
    • 0037224320 scopus 로고    scopus 로고
    • ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma
    • Hernan R., et al. ERBB2 up-regulates S100A4 and several other prometastatic genes in medulloblastoma. Cancer Res. 63 (2003) 140-148
    • (2003) Cancer Res. , vol.63 , pp. 140-148
    • Hernan, R.1
  • 2
    • 33645226815 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells
    • Sonnemann J., et al. Histone deacetylase inhibitors induce cell death and enhance the susceptibility to ionizing radiation, etoposide, and TRAIL in medulloblastoma cells. Int. J. Oncol. 28 (2006) 755-766
    • (2006) Int. J. Oncol. , vol.28 , pp. 755-766
    • Sonnemann, J.1
  • 3
    • 0037200078 scopus 로고    scopus 로고
    • Medulloblastoma growth inhibition by hedgehog pathway blockade
    • Berman D.M., et al. Medulloblastoma growth inhibition by hedgehog pathway blockade. Science 297 (2002) 1559-1561
    • (2002) Science , vol.297 , pp. 1559-1561
    • Berman, D.M.1
  • 4
    • 20444468917 scopus 로고    scopus 로고
    • Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics
    • Romer J., and Curran T. Targeting medulloblastoma: small-molecule inhibitors of the Sonic Hedgehog pathway as potential cancer therapeutics. Cancer Res. 65 (2005) 4975-4978
    • (2005) Cancer Res. , vol.65 , pp. 4975-4978
    • Romer, J.1    Curran, T.2
  • 5
    • 0037447269 scopus 로고    scopus 로고
    • Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions
    • Williams J.A., et al. Identification of a small molecule inhibitor of the hedgehog signaling pathway: effects on basal cell carcinoma-like lesions. Proc. Natl. Acad. Sci. U S A 100 (2003) 4616-4621
    • (2003) Proc. Natl. Acad. Sci. U S A , vol.100 , pp. 4616-4621
    • Williams, J.A.1
  • 6
    • 0037195074 scopus 로고    scopus 로고
    • Small molecule modulation of Smoothened activity
    • Chen J.K., et al. Small molecule modulation of Smoothened activity. Proc. Natl. Acad. Sci. U S A 99 (2002) 14071-14076
    • (2002) Proc. Natl. Acad. Sci. U S A , vol.99 , pp. 14071-14076
    • Chen, J.K.1
  • 7
    • 0042967678 scopus 로고    scopus 로고
    • BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect
    • Hallahan A.R., et al. BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect. Nat. Med. 9 (2003) 1033-1038
    • (2003) Nat. Med. , vol.9 , pp. 1033-1038
    • Hallahan, A.R.1
  • 8
    • 0141567515 scopus 로고    scopus 로고
    • All-trans-retinoic acid-induced apoptosis in human medulloblastoma: activation of caspase-3/poly(ADP-ribose) polymerase 1 pathway
    • Gumireddy K., et al. All-trans-retinoic acid-induced apoptosis in human medulloblastoma: activation of caspase-3/poly(ADP-ribose) polymerase 1 pathway. Clin. Cancer Res. 9 (2003) 4052-4059
    • (2003) Clin. Cancer Res. , vol.9 , pp. 4052-4059
    • Gumireddy, K.1
  • 9
    • 13444279877 scopus 로고    scopus 로고
    • Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid
    • Di C., et al. Identification of OTX2 as a medulloblastoma oncogene whose product can be targeted by all-trans retinoic acid. Cancer Res. 65 (2005) 919-924
    • (2005) Cancer Res. , vol.65 , pp. 919-924
    • Di, C.1
  • 10
    • 33644518372 scopus 로고    scopus 로고
    • Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation
    • Su X., et al. Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Mol. Cell Biol. 26 (2006) 1666-1678
    • (2006) Mol. Cell Biol. , vol.26 , pp. 1666-1678
    • Su, X.1
  • 11
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Singh S.K., et al. Identification of a cancer stem cell in human brain tumors. Cancer Res. 63 (2003) 5821-5828
    • (2003) Cancer Res. , vol.63 , pp. 5821-5828
    • Singh, S.K.1
  • 12
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh S.K., et al. Identification of human brain tumour initiating cells. Nature 432 (2004) 396-401
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1
  • 13
    • 22844437215 scopus 로고    scopus 로고
    • Isolation of neural stem cells from the postnatal cerebellum
    • Lee A., et al. Isolation of neural stem cells from the postnatal cerebellum. Nat. Neurosci. 8 (2005) 723-729
    • (2005) Nat. Neurosci. , vol.8 , pp. 723-729
    • Lee, A.1
  • 14
    • 26644435531 scopus 로고    scopus 로고
    • Radial glia cells are candidate stem cells of ependymoma
    • Taylor M.D., et al. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8 (2005) 323-335
    • (2005) Cancer Cell , vol.8 , pp. 323-335
    • Taylor, M.D.1
  • 15
    • 0030866154 scopus 로고    scopus 로고
    • Altered neural cell fates and medulloblastoma in mouse patched mutants
    • Goodrich L.V., et al. Altered neural cell fates and medulloblastoma in mouse patched mutants. Science 277 (1997) 1109-1113
    • (1997) Science , vol.277 , pp. 1109-1113
    • Goodrich, L.V.1
  • 16
    • 12344301234 scopus 로고    scopus 로고
    • In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice
    • Sanchez P., and Ruiz i Altaba A. In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice. Mech. Dev. 122 (2005) 223-230
    • (2005) Mech. Dev. , vol.122 , pp. 223-230
    • Sanchez, P.1    Ruiz i Altaba, A.2
  • 17
    • 4544285754 scopus 로고    scopus 로고
    • Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice
    • Romer J.T., et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. Cancer Cell 6 (2004) 229-240
    • (2004) Cancer Cell , vol.6 , pp. 229-240
    • Romer, J.T.1
  • 18
    • 0037112420 scopus 로고    scopus 로고
    • Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1
    • Weiner H.L., et al. Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1. Cancer Res. 62 (2002) 6385-6389
    • (2002) Cancer Res. , vol.62 , pp. 6385-6389
    • Weiner, H.L.1
  • 19
    • 0037902082 scopus 로고    scopus 로고
    • c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice
    • Rao G., et al. c-Myc enhances sonic hedgehog-induced medulloblastoma formation from nestin-expressing neural progenitors in mice. Neoplasia 5 (2003) 198-204
    • (2003) Neoplasia , vol.5 , pp. 198-204
    • Rao, G.1
  • 20
    • 7444228699 scopus 로고    scopus 로고
    • The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas
    • Hallahan A.R., et al. The SmoA1 mouse model reveals that notch signaling is critical for the growth and survival of sonic hedgehog-induced medulloblastomas. Cancer Res. 64 (2004) 7794-7800
    • (2004) Cancer Res. , vol.64 , pp. 7794-7800
    • Hallahan, A.R.1
  • 21
    • 21044435675 scopus 로고    scopus 로고
    • Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma
    • Oliver T.G., et al. Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma. Development 132 (2005) 2425-2439
    • (2005) Development , vol.132 , pp. 2425-2439
    • Oliver, T.G.1
  • 22
    • 0035863498 scopus 로고    scopus 로고
    • Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched
    • Wetmore C., et al. Loss of p53 but not ARF accelerates medulloblastoma in mice heterozygous for patched. Cancer Res. 61 (2001) 513-516
    • (2001) Cancer Res. , vol.61 , pp. 513-516
    • Wetmore, C.1
  • 23
    • 0037112505 scopus 로고    scopus 로고
    • DNA ligase IV suppresses medulloblastoma formation
    • Lee Y., and McKinnon P.J. DNA ligase IV suppresses medulloblastoma formation. Cancer Res. 62 (2002) 6395-6399
    • (2002) Cancer Res. , vol.62 , pp. 6395-6399
    • Lee, Y.1    McKinnon, P.J.2
  • 24
    • 0037219382 scopus 로고    scopus 로고
    • Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice
    • Tong W.M., et al. Null mutation of DNA strand break-binding molecule poly(ADP-ribose) polymerase causes medulloblastomas in p53(-/-) mice. Am. J. Pathol. 162 (2003) 343-352
    • (2003) Am. J. Pathol. , vol.162 , pp. 343-352
    • Tong, W.M.1
  • 25
    • 0034656212 scopus 로고    scopus 로고
    • Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum
    • Marino S., et al. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. Genes Dev. 14 (2000) 994-1004
    • (2000) Genes Dev. , vol.14 , pp. 994-1004
    • Marino, S.1
  • 26
    • 0141482110 scopus 로고    scopus 로고
    • Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice
    • Zindy F., et al. Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice. Cancer Res. 63 (2003) 5420-5427
    • (2003) Cancer Res. , vol.63 , pp. 5420-5427
    • Zindy, F.1
  • 27
    • 27744450224 scopus 로고    scopus 로고
    • The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation
    • Uziel T., et al. The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation. Genes Dev. 19 (2005) 2656-2667
    • (2005) Genes Dev. , vol.19 , pp. 2656-2667
    • Uziel, T.1
  • 28
    • 0037165140 scopus 로고    scopus 로고
    • Prediction of central nervous system embryonal tumour outcome based on gene expression
    • Pomeroy S.L., et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature 415 (2002) 436-442
    • (2002) Nature , vol.415 , pp. 436-442
    • Pomeroy, S.L.1
  • 29
    • 20244370527 scopus 로고    scopus 로고
    • Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells
    • Hartmann W., et al. Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells. Am. J. Pathol. 166 (2005) 1153-1162
    • (2005) Am. J. Pathol. , vol.166 , pp. 1153-1162
    • Hartmann, W.1
  • 30
    • 0034665975 scopus 로고    scopus 로고
    • Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma
    • Hahn H., et al. Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma. J. Biol. Chem. 275 (2000) 28341-28344
    • (2000) J. Biol. Chem. , vol.275 , pp. 28341-28344
    • Hahn, H.1
  • 31
    • 4444273153 scopus 로고    scopus 로고
    • Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice
    • Rao G., et al. Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice. Oncogene 23 (2004) 6156-6162
    • (2004) Oncogene , vol.23 , pp. 6156-6162
    • Rao, G.1
  • 32
    • 33645094926 scopus 로고    scopus 로고
    • N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma
    • Browd S.R., et al. N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma. Cancer Res. 66 (2006) 2666-2672
    • (2006) Cancer Res. , vol.66 , pp. 2666-2672
    • Browd, S.R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.