Human ABCA1 BAC Transgenic Mice Show Increased High Density Lipoprotein Cholesterol and ApoAI-dependent Efflux Stimulated by an Internal Promoter Containing Liver X Receptor Response Elements in Intron

Journal of Biological Chemistry

Volumn 276, Issue 36, 2001, Pages 33969-33979

  Singaraja, Roshni R ^a   Bocher, Virginie ^b   James, Erick R ^c   Clee, Susanne M ^a   Zhang, Lin Hua ^c   Leavitt, Blair R ^a   Tan, Bing ^d   Brooks Wilson, Angela ^c   Kwok, Ahita ^a   Bissada, Nagat ^a   Yang, Yu Zhou ^a   Liu, Guoqing ^a   Tafuri, Sherrie R ^d   Fievet, Catherine ^b   Wellington, Cheryl L ^a   Staels, Bart ^b   Hayden, Michael R ^a,e  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b INSTITUT PASTEUR DE LILLE   (France)

^c Xenon Genetics Inc   (Canada)

^d PFIZER INC   (United States)

^e Centre for Molecular Medicine and Therapeutics   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; CHOLESTEROL; PROTEINS;

TRANSGENIC MICE;

BIOCHEMISTRY;

APOLIPOPROTEIN A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; RETINOID X RECEPTOR; ABC TRANSPORTER; ABC TRANSPORTER A1; CELL RECEPTOR; CHOLESTEROL; DNA BINDING PROTEIN; LIPID; LIVER X RECEPTOR; MESSENGER RNA; RETINOIC ACID RECEPTOR; THYROID HORMONE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; GENE EXPRESSION REGULATION; IMMUNOCYTOCHEMISTRY; INTRON; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR DENSITY; RECEPTOR UPREGULATION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; ANIMAL; BIOLOGICAL MODEL; BLOOD; CELL CULTURE; CELL LINE; CELL STRAIN COS1; DNA RESPONSIVE ELEMENT; GENETIC TRANSFECTION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; LIVER; MACROPHAGE; METABOLISM; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSACTIVATION;

ANIMALIA; MUS MUSCULUS;

ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; CELL LINE; CELLS, CULTURED; CHOLESTEROL; CHOLESTEROL, HDL; CLONING, MOLECULAR; COS CELLS; DNA-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; INTRONS; LIPIDS; LIVER; MACROPHAGES; MICE; MICE, TRANSGENIC; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; RESPONSE ELEMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0035823531     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M102503200     Document Type: Article

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