메뉴 건너뛰기




Volumn 27, Issue 8, 2006, Pages 742-747

Characterization of CHEK2 mutations in prostate cancer

Author keywords

CHEK2; CHK2; Kinase; Prostate cancer

Indexed keywords

CHECKPOINT KINASE 2;

EID: 33746943715     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.20321     Document Type: Article
Times cited : (31)

References (38)
  • 1
    • 0037073737 scopus 로고    scopus 로고
    • Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation
    • Ahn J, Prives C. 2002. Checkpoint kinase 2 (Chk2) monomers or dimers phosphorylate Cdc25C after DNA damage regardless of threonine 68 phosphorylation. J Biol Chem 277:48418-48426.
    • (2002) J Biol Chem , vol.277 , pp. 48418-48426
    • Ahn, J.1    Prives, C.2
  • 2
    • 0034326802 scopus 로고    scopus 로고
    • Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation
    • Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE. 2000. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res 60:5934-5936.
    • (2000) Cancer Res , vol.60 , pp. 5934-5936
    • Ahn, J.Y.1    Schwarz, J.K.2    Piwnica-Worms, H.3    Canman, C.E.4
  • 3
    • 0037205422 scopus 로고    scopus 로고
    • Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain
    • Ahn JY, Li X, Davis HL, Canman CE. 2002. Phosphorylation of threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated domain. J Biol Chem 277:19389-19395.
    • (2002) J Biol Chem , vol.277 , pp. 19389-19395
    • Ahn, J.Y.1    Li, X.2    Davis, H.L.3    Canman, C.E.4
  • 4
    • 11144265895 scopus 로고    scopus 로고
    • Loss of RPA1 induces Chk2 phosphorylation through a caffeine-sensitive pathway
    • Araya R, Hirai I, Meyerkord CL, Wang HG. 2005. Loss of RPA1 induces Chk2 phosphorylation through a caffeine-sensitive pathway. FEBS Lett 579:157-161.
    • (2005) FEBS Lett , vol.579 , pp. 157-161
    • Araya, R.1    Hirai, I.2    Meyerkord, C.L.3    Wang, H.G.4
  • 5
    • 0038418869 scopus 로고    scopus 로고
    • Chk1 and Chk2 kinases in checkpoint control and cancer
    • Bartek J, Lukas J. 2003. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 3:421-429.
    • (2003) Cancer Cell , vol.3 , pp. 421-429
    • Bartek, J.1    Lukas, J.2
  • 9
    • 0034142325 scopus 로고    scopus 로고
    • Chk2/ hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53
    • Chehab NH, Malikzay A, Appel M, Halazonetis TD. 2000. Chk2/ hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53. Genes Dev 14:278-288.
    • (2000) Genes Dev , vol.14 , pp. 278-288
    • Chehab, N.H.1    Malikzay, A.2    Appel, M.3    Halazonetis, T.D.4
  • 11
    • 0037224465 scopus 로고    scopus 로고
    • Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array
    • Dong, Y, Zhang H, Hawthorn L, Ganther HE, Ip C. 2003. Delineation of the molecular basis for selenium-induced growth arrest in human prostate cancer cells by oligonucleotide array. Cancer Res 63:52-59.
    • (2003) Cancer Res , vol.63 , pp. 52-59
    • Dong, Y.1    Zhang, H.2    Hawthorn, L.3    Ganther, H.E.4    Ip, C.5
  • 12
    • 0033638454 scopus 로고    scopus 로고
    • The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms
    • Durocher D, Taylor IA, Sarbassova D, Haire LF, Westcott SL, Jackson SP, Smerdon SJ, Yaffe MB. 2000. The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms. Mol Cell 6:1169-1182.
    • (2000) Mol Cell , vol.6 , pp. 1169-1182
    • Durocher, D.1    Taylor, I.A.2    Sarbassova, D.3    Haire, L.F.4    Westcott, S.L.5    Jackson, S.P.6    Smerdon, S.J.7    Yaffe, M.B.8
  • 13
    • 0035817764 scopus 로고    scopus 로고
    • Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway
    • Falck J, Lukas C, Protopopova M, Lukas J, Selivanova G, Bartek J. 2001a. Functional impact of concomitant versus alternative defects in the Chk2-p53 tumour suppressor pathway. Oncogene 20:5503-5510.
    • (2001) Oncogene , vol.20 , pp. 5503-5510
    • Falck, J.1    Lukas, C.2    Protopopova, M.3    Lukas, J.4    Selivanova, G.5    Bartek, J.6
  • 14
    • 0035848819 scopus 로고    scopus 로고
    • The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
    • Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J. 2001b. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410:842-847.
    • (2001) Nature , vol.410 , pp. 842-847
    • Falck, J.1    Mailand, N.2    Syljuasen, R.G.3    Bartek, J.4    Lukas, J.5
  • 17
    • 0034624718 scopus 로고    scopus 로고
    • Cds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
    • Lee JS, Collins KM, Brown AL, Lee CH, Chung JH. 2000. hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature 404:201-204.
    • (2000) Nature , vol.404 , pp. 201-204
    • Lee, J.S.1    Collins, K.M.2    Brown, A.L.3    Ch, L.4    Chung, J.H.5
  • 20
    • 15744386741 scopus 로고    scopus 로고
    • Regulation of Chk2 by DNA-dependent protein kinase
    • Li J, Stern DF. 2005. Regulation of Chk2 by DNA-dependent protein kinase. J Biol Chem 280:12041-12050.
    • (2005) J Biol Chem , vol.280 , pp. 12041-12050
    • Li, J.1    Stern, D.F.2
  • 22
    • 0035878816 scopus 로고    scopus 로고
    • Reduced expression and impaired kinase activity of a Chk2 mutant identified in human lung cancer
    • Matsuoka S, Nakagawa T, Masuda A, Haruki N, Elledge SJ, Takahashi T. 2001. Reduced expression and impaired kinase activity of a Chk2 mutant identified in human lung cancer. Cancer Res 61:5362-5365.
    • (2001) Cancer Res , vol.61 , pp. 5362-5365
    • Matsuoka, S.1    Nakagawa, T.2    Masuda, A.3    Haruki, N.4    Elledge, S.J.5    Takahashi, T.6
  • 23
    • 16344381702 scopus 로고    scopus 로고
    • p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation
    • Ou YH, Chung PH, Sun TP, Shieh SY. 2005. p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation. Mol Biol Cell 16:1684-1695.
    • (2005) Mol Biol Cell , vol.16 , pp. 1684-1695
    • Ou, Y.H.1    Chung, P.H.2    Sun, T.P.3    Shieh, S.Y.4
  • 24
    • 0037795780 scopus 로고    scopus 로고
    • Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation
    • Schwarz JK, Lovly CM, Piwnica-Worms H. 2003. Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation. Mol Cancer Res 1:598-609.
    • (2003) Mol Cancer Res , vol.1 , pp. 598-609
    • Schwarz, J.K.1    Lovly, C.M.2    Piwnica-Worms, H.3
  • 25
    • 0038752083 scopus 로고    scopus 로고
    • Chk2 activates E2F-1 in response to DNA damage
    • Stevens C, Smith L, La Thangue NB. 2003. Chk2 activates E2F-1 in response to DNA damage. Nat Cell Biol 5:401-409.
    • (2003) Nat Cell Biol , vol.5 , pp. 401-409
    • Stevens, C.1    Smith, L.2    La Thangue, N.B.3
  • 26
    • 0032504069 scopus 로고    scopus 로고
    • Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint
    • Sun Z, Hsiao J, Fay DS, Stern DF. 1998. Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint. Science 281:272-274.
    • (1998) Science , vol.281 , pp. 272-274
    • Sun, Z.1    Hsiao, J.2    Fay, D.S.3    Stern, D.F.4
  • 29
    • 10644270921 scopus 로고    scopus 로고
    • p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2
    • Urist M, Tanaka T, Poyurovsky MV, Prives C. 2004. p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2. Genes Dev 18:3041-3054.
    • (2004) Genes Dev , vol.18 , pp. 3041-3054
    • Urist, M.1    Tanaka, T.2    Poyurovsky, M.V.3    Prives, C.4
  • 30
    • 0035930536 scopus 로고    scopus 로고
    • Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks
    • Ward IM, Wu X, Chen J. 2001. Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks. J Biol Chem 276:47755-57758.
    • (2001) J Biol Chem , vol.276 , pp. 47755-57758
    • Ward, I.M.1    Wu, X.2    Chen, J.3
  • 31
    • 14844333117 scopus 로고    scopus 로고
    • TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on Thr68
    • Wei JH, Chou YF, Ou YH, Ye YS, Tyan SW, Sun TP, Shen CY, Shieh SY. 2004. TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on Thr68. J Biol Chem 280:7748-7757.
    • (2004) J Biol Chem , vol.280 , pp. 7748-7757
    • Wei, J.H.1    Chou, Y.F.2    Ou, Y.H.3    Ye, Y.S.4    Tyan, S.W.5    Sun, T.P.6    Shen, C.Y.7    Shieh, S.Y.8
  • 32
    • 0347262257 scopus 로고
    • Identical short peptide sequences in unrelated proteins can have different conformations: A testing ground for theories of immune recognition
    • Wilson IA, Haft DH, Getzoff ED, Tainer JA, Lerner RA, Brenner S. 1985. Identical short peptide sequences in unrelated proteins can have different conformations: a testing ground for theories of immune recognition. Proc Natl Acad Sci USA 82:5255-5259.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 5255-5259
    • Wilson, I.A.1    Haft, D.H.2    Getzoff, E.D.3    Tainer, J.A.4    Lerner, R.A.5    Brenner, S.6
  • 33
    • 0035951809 scopus 로고    scopus 로고
    • Characterization of tumor-associated Chk2 mutations
    • Wu X, Webster SR, Chen J. 2001. Characterization of tumor-associated Chk2 mutations. J Biol Chem 276:2971-2974.
    • (2001) J Biol Chem , vol.276 , pp. 2971-2974
    • Wu, X.1    Webster, S.R.2    Chen, J.3
  • 34
    • 0141704306 scopus 로고    scopus 로고
    • Autophosphorylation of checkpoint kinase 2 at serine 516 is required for radiation-induced apoptosis
    • Wu X, Chen J. 2003. Autophosphorylation of checkpoint kinase 2 at serine 516 is required for radiation-induced apoptosis. J Biol Chem 278:36163-36168.
    • (2003) J Biol Chem , vol.278 , pp. 36163-36168
    • Wu, X.1    Chen, J.2
  • 35
    • 0036258583 scopus 로고    scopus 로고
    • Chk2 activation and phosphorylation-dependent oligomerization
    • Xu X, Tsvetkov LM, Stern DF. 2002. Chk2 activation and phosphorylation-dependent oligomerization. Mol Cell Biol 22:4419-4432.
    • (2002) Mol Cell Biol , vol.22 , pp. 4419-4432
    • Xu, X.1    Tsvetkov, L.M.2    Stern, D.F.3
  • 36
    • 0036847998 scopus 로고    scopus 로고
    • PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2
    • Yang S, Kuo C, Bisi JE, Kim MK. 2002. PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2. Nat Cell Biol 4:865-870.
    • (2002) Nat Cell Biol , vol.4 , pp. 865-870
    • Yang, S.1    Kuo, C.2    Bisi, J.E.3    Kim, M.K.4
  • 38
    • 0034707047 scopus 로고    scopus 로고
    • The DNA damage response: Putting checkpoints in perspective
    • Zhou BB, Elledge SJ. 2000. The DNA damage response: putting checkpoints in perspective. Nature 408:433-439.
    • (2000) Nature , vol.408 , pp. 433-439
    • Zhou, B.B.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.