P21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating protein

Proceedings of the National Academy of Sciences of the United States of America

Volumn 89, Issue 5, 1992, Pages 1587-1591

  Duronio, Vincent ^a   Welham, Melanie J ^a   Abraham, Samuel ^a   Dryden, Peter ^a,b   Schrader, John W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b JACK BELL RESEARCH CENTRE   (Canada)

Author keywords

Cytokines; Growth factor; Mast cell; Signal transduction

Indexed keywords

CELL SURFACE RECEPTOR; CYTOKINE; DRUG DERIVATIVE; GTP BINDING PROTEINS; GTPASE ACTIVATING PROTEINS; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; INTERLEUKIN 3; ONCOPROTEIN; PHOSPHOTYROSINE; PROTEIN; PROTEIN KINASE C; PROTEIN P21; PROTEIN TYROSINE KINASE; PROTO ONCOGENE PROTEIN C KIT; PROTO ONCOGENE PROTEIN P21(RAS); PROTO ONCOGENE PROTEINS; RAS GTPASE ACTIVATING PROTEINS; STEM CELL FACTOR RECEPTOR; TYROSINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN RECEPTOR;

ANIMAL; ARTICLE; CELL CULTURE; IN VITRO STUDY; MAST CELL; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION; ANIMAL CELL; CONTROLLED STUDY; GENE ACTIVATION; MEGAKARYOCYTE; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING;

ANIMAL; CELLS, CULTURED; CYTOKINES; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; GUANOSINE TRIPHOSPHATE; IN VITRO; INTERLEUKIN-3; MAST CELLS; MICE; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN KINASE C; PROTEIN-TYROSINE KINASE; PROTEINS; PROTO-ONCOGENE PROTEIN C-KIT; PROTO-ONCOGENE PROTEIN P21(RAS); PROTO-ONCOGENE PROTEINS; RAS GTPASE-ACTIVATING PROTEINS; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TYROSINE;

EID: 0026611951     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.89.5.1587     Document Type: Article

References (40)

1. Schrader, J. W., Ziltener, H. J. & Leslie, K. B. (1986) Proc. Natl. Acad. Sci. USA 83, 2458-2462.
2. Cosman, D., Lyman, S. D., Idzerda, R. L., Beckmann, M. P., Park, L. S., Goodwin, R. G. & March, C. J. (1990) Trends Biochem. Sci. 15, 265-270.
3. Hatakeyama, M., Kono, T., Kobayashi, N., Kawahara, A., Levin, S. D., Perlmutter, R. M. & Taniguchi, T. (1991) Science 252, 1523-1528.
4. Barbacid, M. (1987) Annu. Rev. Biochem. 56, 779-827.
5. Mulcahy, L. S., Smith, M. R. & Stacey, D. W. (1985) Nature (London) 313, 241-243.
6. Smith, M. R., DeGudicibus, S. J. & Stacey, D. W. (1986) Nature (London) 320, 540-543.
7. Gibbs, J. B., Marshall, M. S., Scolnick, E. M., Dixon, R. A. F. & Vogel, U. S. (1991) J. Biol. Chem. 265, 20437-20442.
8. Satoh, T., Endo, M., Nakafuku, M., Nakamura, S. & Kaziro, Y. (1990) Proc Natl. Acad. Sci. USA 87, 5993-5997.
9. Satoh, T., Endo, M., Nakafuku, M., Akiyama, T., Yamamoto, T. & Kaziro, Y. (1990) Proc. Natl. Acad. Sci. USA 87, 7926-7929.
10. Downward, J., Graves, J. D., Warne, P. H., Rayter, S. & Cantrell, D. A. (1990) Nature (London) 346, 719-723.
11. Farnsworth, C. L., Marshall, M. S., Gibbs, J. B., Stacey, D. W. & Feig, L. A. (1991) Cell 64, 625-633.
12. Trahey, M. & McCormick, F. (1987) Science 238, 542-545.
13. Clark-Lewis, I., Aebersold, R., Ziltener, H. J., Schrader, J. W., Hood, L. E. & Kent, S. B. H. (1986) Science 231, 134-137.
14. Karasuyama, H. & Melchers, F. (1988) Eur. J. Immunol. 18, 97-104.
15. Furth, M. E., Davis, L. J., Fleurdelys, B. & Scolnick, E. (1982) J. Virol. 43, 294-304.
16. Clark-Lewis, I., Kent, S. B. H. & Schrader, J. W. (1984) J. Biol. Chem. 259, 7488-7494.
17. Dexter, T. M., Garland, J., Scott, D., Scolnick, E. & Metcalf, D. (1980) J. Exp. Med. 152, 1036-1047.
18. LeGros, G. S., Gillis, S. & Watson, J. D. (1985) J. Immunol. 135, 4009-4014.
19. Cashel, M., Lazzarini, R. A. & Kalbacher, B. (1969) J. Chromatogr. 40, 103-109.
20. Reedijk, M., Liu, X. & Pawson, T. (1990) Mol. Cell. Biol. 10, 5601-5608.
21. Welham, M. J. & Wyke, J. A. (1988) J. Virol. 62, 1898-1906.
22. Tamaoki, T., Nomoto, H., Takahashi, I., Kato, Y., Morimoto, M. & Tomita, F. (1986) Biochem. Biophys. Res. Commun. 135, 397-402.
23. Davis, P. D., Hill, C. H., Keech, E., Lawton, G., Nixon, J. S., Sedwick, A. D., Wadsworth, J., Westmacott, D. & Wilkinson, S. E. (1989) FEES Lett. 259, 61-63.
24. Shiraishi, T., Owada, M. K., Tatsuka, M., Yamashita, T., Watanabe, K. & Kakunaga, T. (1989) Cancer Res. 49, 2374-2378.
25. Gazit, A., Yaish, P., Gilon, C. & Levitzki, A. (1989) J. Med. Chem. 32, 2344-2352.
26. Ellis, C., Moran, M., McCormick, F. & Pawson, T. (1990) Nature (London) 343, 377-381.
27. Kaplan, D. R., Morrison, D. K., Wong, G., McCormick, F. & Williams, L. T. (1990) Cell 61, 125-133.
28. Satoh, T., Nakafuku, M., Miyajima, A. & Kaziro, Y. (1991) Proc. Natl. Acad. Sci. USA 88, 3314-3318.
29. Anderson, D. M., Lyman, S. D., Baird, A., Wignall, J. M., Eisenman, J., Rauch, C., March, C. J., Boswell, H. S., Gimpel, S. D., Cosman, D. & Williams, D. E. (1990) Cell 63, 235-243.
30. Yarden, Y., Kuang, W.-J., Yang-Feng, T., Coussens, L., Munemitsu, S., Dull, T. J., Chen, E., Schlessinger, J., Francke, U. & Ullrich, A. (1987) EMBO J. 6, 3341-3351.
31. Molloy, C., Bottaro, D. P., Fleming, T. P., Marshall, M. S., Gibbs, J. B. & Aaronson, S. A. (1989) Nature (London) 342, 711-714.
32. Moran, M. F., Polakis, P., McCormick, F., Pawson, T. & Ellis, C. (1991) Mol. Cell. Biol. 11, 1804-1812.
33. Rottapel, R., Reedijk, M., Williams, D. E., Lyman, S. D., Anderson, D. M., Pawson, T. & Bernstein, A. (1991) Mol. Cell. Biol. 11, 3043-3051.
34. Downward, J., Riehl, R., Wu, L. & Weinberg, R. A. (1990) Proc. Natl. Acad. Sci. USA 87, 5998-6002.
35. Wolfman, A. & Macara, I. G. (1990) Science 248, 247-249.
36. Xu, G., Lin, B., Tanaka, K., Dunn, D., Wood, D., Gesteland, R., White, R., Weiss, R. & Tamanoi, F. (1990) Cell 63, 835-841.
37. Martin, G. A., Viskochil, D., Bollag, G., McCabe, P. C., Crosier, W. J., Haubruck, H., Conroy, L., Clark, R., O'Connell, P., Cawthon, R. M., Innis, M. A. & McCormick, F. (1990) Cell 63, 843-849.
38. Farrar, W. L., Garcia, G. G., Evans, G., Michiel, D. & Linnekin, D. (1990) Cytokines 2, 77-91.
39. Morla, A. O., Schreurs, J., Miyajima, A. & Wang, J. Y. J. (1988) Mol. Cell. Biol. 8, 2214-2218.
40. Burgering, B. M. T., Medema, R. H., Maassen, J. A., van de Wetering, M. L., van der Eb, A. J., McCormick, F. & Bos, J. L. (1991) EMBO J. 10, 1103-1109.