TH2-type cytokines in asthma

Annals of the New York Academy of Sciences

Volumn 796, Issue , 1996, Pages 1-8

  Kay, A B ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN E; INTERLEUKIN 3; INTERLEUKIN 5;

ALLERGIC ASTHMA; ANTIGEN RECOGNITION; ASTHMA; CELL DIFFERENTIATION; CELL FUNCTION; CELL SECRETION; CELL SURVIVAL; CONFERENCE PAPER; EFFECTOR CELL; EOSINOPHIL; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOGLOBULIN PRODUCTION; MACROPHAGE; MAST CELL; T LYMPHOCYTE;

EID: 0029805657     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb32561.x     Document Type: Conference Paper

References (45)

1. CLUTTERBUCK, E. J., E. M. A. HIRST & C. J. SANDERSON. 1989. Human interleukin-5 (IL-5) regulates the production of eosinophils in human bone marrow cultures: Comparison and interaction with IL-1, IL-3, IL-6 and GM-CSF. Blood 73: 1504-1513.
2. DENT, L. A., M. STRATH, A. L. MELLOR & C. J. SANDERSON. 1990. Eosinophilia in transgenic mice expressing interleukin-5. J. Exp. Med. 172: 1425-1431.
3. SEHMI, R., A. J. WARDLAW, O. CROMWELL, K. KURIHARA, P. WALTMANN & A. B. KAY. 1992. Interleukin-5 (IL-5) selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. Blood 79: 2952-2959.
4. BAGGIOLINI, M. & C. A. DAHINDEN. 1994. CC chemokines in allergic inflammation. Immunol. Today 15: 127-133.
5. YING, S., L. TABORDA-BARATA, Q. MENG, M. HUMBERT & A. B. KAY. 1995. The kinetics of allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 (MCP-3) and RANTES in the skin of human atopic subjects: Relationship to eosinophil, T-cell and macrophage recruitment. J. Exp. Med. 181: 2153-2159.
6. WALSH, G. M., A. HARTNELL, A. J. WARDLAW, K. KURIHARA, C. J. SANDERSON & A. B. KAY. 1990. IL-5 enhances the in vitro adhesion of human esoinophils, but not neutrophils, in a leucocyte integrin (CD11/CD18)-dependent manner. Immunology 71: 258-265.
7. WALSH, G. M., A. HARTNELL, J.-J. MERMOD, A. B. KAY & A. J. WARDLAW. 1991. Human eosinophil, but not neutrophil adherence to IL-1 stimulated HUVEC is α4β1 (VLA-4) dependent. J. Immunol. 146: 3419-3423.
8. SHAW, R. J., G. M. WALSH, O. CROMWELL, R. MOQBEL, C. J. F. SPRY & A. B. KAY. 1985. Activated human eosinophils generate SRS-A leukotrienes following physiological (IgG-dependent) stimulation. Nature 316: 150-152.
9. CROMWELL, O., A. J. WARDLAW, A. CHAMPION, R. MOQBEL, D. OSEI & A. B. KAY. 1990. IgG-dependent generation of platelet-activating factor by normal and low density human eosinophils. J. Immunol. 145: 3862-3868.
10. 4 receptor antagonist improves pulmonary function in patients with mild, chronic asthma. Am. Rev. Respir. Dis. 140: 1336-1339.
11. AYARS, G. H., L. C. ALTMAN, G. J. GLEICH, D. A. LOEGERING & E. B. BAKER. 1985. Eosinophil and eosinophil granule mediated pneumocyte injury. J. Allergy Clin. Immunol. 76: 595-604.
12. GUNDEL, R. H., L. G. LETTS & G. J. GLEICH. 1991. Human eosinophil major basic protein induces airway constriction and airway hyperresponsiveness in primates. J. Clin. Invest. 87: 1470-1473.
13. GLEICH, G. J. 1990. The eosinophil and bronchial asthma: Current understanding. J. Allergy Clin. Immunol. 85: 422-436.
14. ABU-GHAZALEH, R. I., T. FUJISAWA, J. MESTECKY, R. A. KYLE & G. J. GLEICH. 1989. IgA-induced eosinophil degranulation. J. Immunol. 142: 2393-2400.
15. KHALIFFE, J., M. CAPRON, J. Y. CESBRON, P.-C. TAI, H. TAELMAN, L. PRIN & A. CAPRON. 1986. Role of specific IgE antibodies in peroxidase (EPO) release from human eosinophils. J. Immunol. 137: 1659-1664.
16. KROEGEL, C., T. YUKAWA, G. DENT, P. VENGE, K. F. CHUNG & P. J. BARNES. 1989. Stimulation of degranulation from human eosinophils by platelet-activating factor. J. Immunol. 142: 3518-3526.
17. ANWAR, A. R. E., G. M. WALSH, O. CROMWELL, A. B. KAY & A. J. WARDLAW. 1994. Adhesion to fibronectin primes eosinophils via VLA-4. Immunology 82: 222-228.
18. WONG, D. T., P. F. WELLER, S. J. GALLI, A. ELOVIC, T. H. RAND, G. T. GALLAGHER, T. CHIANG, M. Y. CHOU, K. MATOSSIAN, J. MCBRIDE & R. TODD. 1990. Human eosinophils express transforming growth factor alpha. J. Exp. Med. 172: 673-681.
19. MOQBEL, R., Q. HAMID, S. YING, J. BARKANS, A. HARTNELL, A. TSICOPOULOS, A. J. WARDLAW & A. B. KAY. 1991. Expression of mRNA and immunoreactivity for the granulocyte/macrophage colony stimulating factor (GM-CSF) in activated human eosinophils. J. Exp. Med. 174: 749-752.
20. KITA, H., T. OHNISHI, Y. OKUBO, D. WELLER, J. S. ABRAMS & G. J. GLEICH. 1991. GM-CSF and interleukin-3 release from human peripheral blood eosinophils and neutrophils. J. Exp. Med. 174: 743-748.
21. DEL POZO, V., B. DE ANDRES, E. MARTIN, N. MARURI, J. M. ZUBELDIA, P. PALOMINO & C. LAHOZ. 1990. Murine eosinophils and IL-1: alpha IL-1 mRNA detection by in situ hybridization. Production and release of IL-1 from peritoneal eosinophils. J. Immunol. 199: 3117-3122.
22. BRAUN, R. K., M. FRANCHINI, F. ERARD, S. RIHS, I. J. M. DE VRIES, K. BLASER, T. T. HANSEL & C. WALKER. 1993. Human peripheral blood eosinophils produce and release interleukin-8 on stimulation with calcium ionophore. Eur. J. Immunol. 23: 956-960.
23. DESREUMAUX, P., A. JANIN, J. F. COLOMBEL, L. PRIN, J. PLUMAS, G. TORPIER, A. CAPRON & M. CAPRON. 1992. Interleukin-5 mRNA expression by eosinophils in the intestinal mucosa of patients with coeliac disease. J. Exp. Med. 175: 293-296.
24. AZZAWI, M., P. W. JOHNSTON, S. MAJUMDAR, A. B. KAY & P. K. JEFFERY. 1992. T lymphocytes and activated eosinophils in airway mucosa in fatal asthma and cystic fibrosis. Am. Rev. Respir. Dis. 145: 1477-1482.
25. FILLEY, W. V., K. E. HOLLEY, G. M. KEPHART & G. J. GLEICH. 1982. Identification by immunofluorescence of eosinophil granule major basic protein in lung tissues of patients with bronchial asthma. Lancet ii: 11-16.
26. DURHAM, S. R. & A. B. KAY. 1985. Eosinophils, bronchial hyperreactivity and latephase asthmatic reactions. Clin. Allergy 15: 411-418.
27. BOUSQUET, J., P. CHANEZ, J. Y. LACOSTE, G. BARNEON, N. GAVANIAN, I. ENANDER, P. VENGE, S. AHLSTEDT, J. SIMONY-LAFONTAINE, PH. GODARD & F.-B. MICHEL. 1990. Eosinophilic inflammation in asthma. New Eng. J. Med. 323: 1033-1039.
28. WARDLAW, A. J., S. DUNNETTE, G. J. GLEICH, J. V. COLLINS & A. B. KAY. 1988. Eosinophils and mast cells in bronchoalveolar lavage in mild asthma: Relationship to bronchial hyperreactivity. Am. Rev. Respir. Dis. 137: 62-69.
29. DIAZ, P., M. C. GONZALEZ, F. R. GALLEGUILLOS, P. ANCIC, O. CROMWELL, D. SHEPHERD, S. R. DURHAM, G. J. GLEICH & A. B. KAY. 1989. Leukocytes and lipid mediators in bronchoalveolar lavage during allergen-induced late-phase asthmatic reactions. Am. Rev. Respir. Dis. 139: 1383-1389.
30. METZGER, W. J., D. ZAVALA, H. B. RICHERSON, P. MOSELEY, P. IWAMOTA, M. MONICK, K. SJOERDSMA & G. W. HUNNINGHAKE. 1987. Local allergen challenge and bronchoalveolar lavage of allergic asthmatic lungs: Description of the model and local airway inflammation. Am. Rev. Respir. Dis. 135: 433-440.
31. LAM, S., J. LE RICHE, D. PHILLIPS & M. CHAN-YEUNG. 1987. Cellular and protein changes in bronchial lavage fluid after late asthmatic reaction in patients with red cedar asthma. J. Allergy Clin. Immunol. 80: 44-50.
32. DIAZ, P., F. R. GALLEGUILLOS, M. C. GONZALEZ, C. PANTIN & A. B. KAY. 1984. Bronchoalveolar lavage in asthma: The effect of DSCG on leucocyte counts, immunoglobulins and complement. J. Allergy Clin. Immunol. 74: 41-48.
33. ROTHENBERG, M. E., J. PETERSEN, R. L. STEVENS, D. S. SILBERSTEIN, D. T. MCKENZIE, K. F. AUSTEN & W. F. OWEN. 1989. IL-5 dependent conversion of normodense human eosinophils to the hypodense phenotype uses 3T3 fibroblasts for enhanced viability, accelerated hypodensity and sustained antibody-dependent cytotoxicity. J. Immunol. 143: 2311-2316.
34. ROTHENBERG, M. E., W. F. OWEN, D. S. SILBERSTEIN, J. WOODS, R. J. SOBERMAN, K. F. AUSTEN & R. L. STEVENS. 1988. Human eosinophils have prolonged survival, enhanced functional properties and become hypodense when exposed to human interleukin-3. J. Clin. Invest. 81: 1986-1992.
35. LOPEZ, A. F., D. J. WILLIAMSON, J. R. GAMBLE, C. G. BEGLEY, J. M. HARIAN, S. J. KLEBANOFF, A. WALTERSDORPH, G. WONG, S. C. CLARK & M. A. VADAS. 1986. Recombinant human granulocyte-macrophage colony stimulating factor stimulates in vitro mature human eosinophil and neutrophil function, surface receptor expression and survival. J. Clin. Invest. 78: 1220-1228.
36. BURD, P. R., H. W. ROGERS, J. R. GORDON, C. A. MARTIN, S. JAYAYAMAN, S. D. WILSON, A. M. DVORAK, S. J. GALLI & M. E. DORF. 1989. Interleukin-3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines. J. Exp. Med. 170: 245-257.
37. HOWELL, C. J., J.-L. PUJOL, A. E. G. CREA, R. DAVIDSON, A. J. H. GEARING, PH. GODARD & T. H. LEE. 1989. Identification of an alveolar macrophage-derived activity in bronchial asthma which enhanced leukotriene C4 generation by human eosinophils stimulated by ionophore (A23187) as granulocyte-macrophage colony-stimulating factor (GM-CSF). Am. Rev. Respir. Dis. 140: 1340-1347.
38. CROMWELL, O., Q. HAMID, C. J. CORRIGAN, J. BARKANS, Q. MENG, P. D. COLLINS & A. B. KAY. 1992. Expression and generation of IL-6, IL-8 and granulocyte-macrophage-colony stimulating factor by human bronchial epithelial cells and enhancement by IL-1-beta and TNF-alpha. Immunology 77: 330-337.
39. BROIDE, D. H., M. M., PAINE & G. S. FIRESTEIN. 1992. Eosinophils express interleukin-5 and granulocyte/macrophage colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J. Clin. Invest. 90: 1414-1424.
40. HAMID, Q., M. AZZAWI, S. YING, R. MOQBEL, A. J. WARDLAW, C. J. CORRIGAN, B. BRADLEY, S. R. DURHAM, J. V. COLLINS, P. K. JEFFERY, D. J. QUINT & A. B. KAY. 1991. Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. J. Clin. Invest. 87: 1541-1546.
41. YING, S., S. R. DURHAM, C. J. CORRIGAN, Q. HAMID & A. B. KAY. 1995. Phenotype of cells expressing mRNA for TH2-type (interleukin-4 and interleukin-5) and TH1-type (interleukin-2 and interferon-gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatics and normal control subjects. Am. J. Respir. Cell Mol. Biol. 12: 477-487.
42. ROBINSON, D. S., Q. HAMID, S. YING, A. TSICOPOULOS, J. BARKANS, A. M. BENTLEY, C. J. CORRIGAN, S. R. DURHAM & A. B. KAY. 1992. Evidence for a predominant "Th2-type" bronchoalveolar lavage T-lymphocyte population in atopic asthma. New Eng. J. Med. 326: 298-304.
43. YING, S., D. S. ROBINSON, V. VARNEY, Q. MENG, A. TSICOPOULOS, R. MOQBEL, S. R. DURHAM, A. B. KAY & Q. HAMID. 1991. TNF-alpha mRNA expression in allergic inflammation. Clin. Exp. Allergy 21: 745-750.
44. WALKER, C., J.-C. VIRCHOW, P. L. B. BRUIJNZEEL & K. BLASER. 1991. T-cell subsets and their soluble products regulate eosinophilia in allergic and non-allergic asthma. J. Immunol. 146: 1829-1835.
45. MOQBEL, R., S. YING, J. BARKANS, T. M. NEWMAN, P. KIMMITT, M. WAKELIN, L. TABORDA-BARATA, Q. MENG, C. J. CORRIGAN, S. R. DURHAM & A. B. KAY. 1995. Identification of mRNA for interleukin-4 in human eosinophils with granule localization and release of the translated product. J. Immunol. 155: 4939-4947.