Structure of UDP-N-acetylglucosamine acyltransferase with a bound antibacterial pentadecapeptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 29, 2006, Pages 10877-10882

  Williams, Allison H ^a   Immormino, Robert M ^a   Gewirth, Daniel T ^a,b   Raetz, Christian R H ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b HAUPTMAN WOODWARD MEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

Antibiotic; Crystal structure; Escherichia coli; Inhibitor; Outer membrane

Indexed keywords

ACYL CARRIER PROTEIN; ACYLTRANSFERASE; ENZYME INHIBITOR; GLUCOSAMINE; HYDROXYL GROUP; LIPID A; PENTADECAPEPTIDE; PEPTIDE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE ACYLTRANSFERASE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BETA SHEET; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; LIPOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION;

ACYLTRANSFERASES; ANTI-BACTERIAL AGENTS; BINDING SITES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ESCHERICHIA COLI; MODELS, MOLECULAR; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN SUBUNITS; STRUCTURAL HOMOLOGY, PROTEIN;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 33746623281     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0604465103     Document Type: Article

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