Computational methods to predict drug safety

Current Computer-Aided Drug Design

Volumn 2, Issue 2, 2006, Pages 151-168

  Patlewicz, Grace ^a  

^a JOINT RESEARCH CENTRE   (Italy)

Author keywords

ADME; Carcinogenicity; Chemical categories; Expert systems; Mutagenicity; Quantitative structure activity relationships; Thresholds of toxicological concern (TTC)

Indexed keywords

SAFETY TESTING;

ADME; CARCINOGENICITY; CHEMICAL CATEGORY; DRUG DISCOVERY; DRUG SAFETY; MUTAGENICITY; PRACTICAL GUIDANCE; PROPERTY; QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP; THRESHOLD OF TOXICOLOGICAL CONCERN;

EXPERT SYSTEMS;

ALDEHYDE DERIVATIVE; ALKENE DERIVATIVE; CARBENE; EPOXIDE; ESTER DERIVATIVE; QUINOLINE DERIVATIVE;

ACIDITY; ALKALINITY; CLASSIFICATION; DRUG ABSORPTION; DRUG CARCINOGENICITY; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG METABOLISM; DRUG RESEARCH; DRUG SAFETY; DRUG SOLUBILITY; INDUSTRY; MATHEMATICAL MODEL; MUTAGENICITY; PARTITION COEFFICIENT; PRACTICE GUIDELINE; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; SHORT SURVEY; TOXICITY TESTING;

EID: 33746233482     PISSN: 15734099     EISSN: None     Source Type: Journal    
DOI: 10.2174/157340906777441735     Document Type: Short Survey

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