Predicting human oral bioavailability of a compound: Development of a novel quantitative structure-bioavailability relationship

Pharmaceutical Research

Volumn 17, Issue 6, 2000, Pages 639-644

  Andrews, C W ^a   Bennett, L ^a,b   Yu, L X ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

Bioavailability; Lipinski's Rule of Five; Quantitative structure bioavailability relationship

Indexed keywords

4 AMINOPYRIDINE; ALCOHOL DERIVATIVE; ALKANOIC ACID; AMIDE; AZIDE; BENZOQUINONE; CARBOXYLIC ACID; FLUORINE; GENERIC DRUG; GUANIDINE DERIVATIVE; IODINE; KETONE DERIVATIVE; NITROGEN DERIVATIVE; PYRAN DERIVATIVE; PYRIDINIUM DERIVATIVE; SALICYLIC ACID; SULFIDE; TETRAZOLE DERIVATIVE; THIOL DERIVATIVE;

ACCURACY; ARTICLE; DATA BASE; DECISION THEORY; DRUG BIOAVAILABILITY; DRUG STRUCTURE; INTERMETHOD COMPARISON; PRIORITY JOURNAL; REGRESSION ANALYSIS; VALIDATION PROCESS;

ADMINISTRATION, ORAL; BIOLOGICAL AVAILABILITY; HUMANS; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033840471     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007556711109     Document Type: Article

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