VolSurf: A new tool for the pharmacokinetic optimization of lead compounds

European Journal of Pharmaceutical Sciences

Volumn 11, Issue SUPPL. 2, 2000, Pages

  Cruciani, Gabriele ^a   Pastor, Manuel ^a   Guba, Wolfgang ^b  

^a UNIVERSITY OF PERUGIA   (Italy)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Blood brain barrier; Caco 2 cell culture; MDCK cell culture; Membrane partitioning; Molecular interaction fields; Virtual screening; VolSurf

Indexed keywords

ACETYLSALICYLIC ACID; ACICLOVIR; ACRIVASTINE; ALPRENOLOL; AMOXICILLIN; ATENOLOL; BRETYLIUM; BRETYLIUM TOSYLATE; CEFALEXIN; CEFATRIZINE; CEFUROXIME; CHLOROTHIAZIDE; DEXAMETHASONE; FUROSEMIDE; GRISEOFULVIN; GUANABENZ; HYDROCHLOROTHIAZIDE; HYDROCORTISONE; KETOPROFEN; LABETALOL; LAMOTRIGINE; METOPROLOL; METOPROLOL TARTRATE; OLSALAZINE; PARACETAMOL; PHENAZONE; RANITIDINE; TERBUTALINE; UNINDEXED DRUG; ZIDOVUDINE;

CELL STRAIN; CELL STRAIN CACO 2; CHEMICAL STRUCTURE; COMPUTER PROGRAM; CONFERENCE PAPER; DRUG ABSORPTION; DRUG SCREENING; HUMAN; HUMAN TISSUE; MODEL; PHARMACOKINETICS; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL;

ANIMAL; BLOOD-BRAIN BARRIER; CACO-2 CELLS; COMPUTER-AIDED DESIGN; HUMAN; LEAD; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SOFTWARE;

EID: 0033800498     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(00)00162-7     Document Type: Conference Paper

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