메뉴 건너뛰기




Volumn 149, Issue 1-3, 2004, Pages 223-234

Toxicology databases and the concept of thresholds of toxicological concern as used by the JECFA for the safety evaluation of flavouring agents

Author keywords

Flavouring agent; Intake; Metabolism; Safety; Toxicity

Indexed keywords

ALCOHOL DERIVATIVE; ALDEHYDE DERIVATIVE; ALIPHATIC COMPOUND; BENZYL DERIVATIVE; CARVONE; CINNAMYL ALCOHOL; ESTER DERIVATIVE; FLAVORING AGENT; HYDROXYL GROUP; IONONE DERIVATIVE; KETONE DERIVATIVE; LACTONE; PHENOL DERIVATIVE; PYRAZINE DERIVATIVE; TERPENOID DERIVATIVE;

EID: 1842716625     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2003.12.034     Document Type: Conference Paper
Times cited : (51)

References (33)
  • 1
    • 0034908759 scopus 로고    scopus 로고
    • Threshold of toxicological concern for chemical substances present in the diet
    • Barlow S.M., Kozianowski G., Wurtzen G., Schlatter J. Threshold of toxicological concern for chemical substances present in the diet. Food Chem. Toxicol. 39:2001;893-905.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 893-905
    • Barlow, S.M.1    Kozianowski, G.2    Wurtzen, G.3    Schlatter, J.4
  • 3
    • 0018079206 scopus 로고
    • Estimation of toxic hazard - A decision tree approach
    • Cramer G.M., Ford R.A., Hall R.L. Estimation of toxic hazard - a decision tree approach. Food Cosmet. Toxicol. 16:1978;255-276.
    • (1978) Food Cosmet. Toxicol. , vol.16 , pp. 255-276
    • Cramer, G.M.1    Ford, R.A.2    Hall, R.L.3
  • 4
    • 0004946641 scopus 로고
    • Toxicological principles for the safety assessment of direct food additives and color additives used in food
    • Draft U.S. Food and Drug Administration. Center for Food Safety and Applied Nutrition, Washington.
    • FDA, 1993. Toxicological principles for the safety assessment of direct food additives and color additives used in food. "Redbook II". Draft U.S. Food and Drug Administration. Center for Food Safety and Applied Nutrition, Washington.
    • (1993) Redbook II
  • 5
    • 0000665493 scopus 로고
    • Food additives; Threshold of regulation for substances used in food-contact articles
    • Federal Register, 1993. Food additives; Threshold of regulation for substances used in food-contact articles. Federal Register 58 (195), 52719-52727.
    • (1993) Federal Register , vol.58 , Issue.195 , pp. 52719-52727
  • 6
    • 0000493162 scopus 로고
    • Food additives; Threshold of regulation for substances used in food-contact articles. Final rule
    • Federal Register, 1995. Food additives; Threshold of regulation for substances used in food-contact articles. Final rule. Federal Register 60 (136), 36582-36594.
    • (1995) Federal Register , vol.60 , Issue.136 , pp. 36582-36594
  • 7
    • 0029153806 scopus 로고
    • The carcinogen bioassay in perspective: Application in identifying human cancer hazards
    • Fung V.A., Barrett J.C., Huff J. The carcinogen bioassay in perspective: application in identifying human cancer hazards. Environ. Health Persp. 103:1995;680-683.
    • (1995) Environ. Health Persp. , vol.103 , pp. 680-683
    • Fung, V.A.1    Barrett, J.C.2    Huff, J.3
  • 8
    • 0024603230 scopus 로고
    • Summary of carcinogenic potency and positivity for 492 rodent carcinogens in the carcinogenic potency database
    • Gold L.S., Slone T.H., Bernstein L. Summary of carcinogenic potency and positivity for 492 rodent carcinogens in the carcinogenic potency database. Environ. Health Persp. 79:1989;259-272.
    • (1989) Environ. Health Persp. , vol.79 , pp. 259-272
    • Gold, L.S.1    Slone, T.H.2    Bernstein, L.3
  • 9
    • 0032725282 scopus 로고    scopus 로고
    • Comparison of two methods to assess the intake of flavouring substances
    • Hall R.L., Ford R.A. Comparison of two methods to assess the intake of flavouring substances. Food Addit. Contam. 16:1999;481-495.
    • (1999) Food Addit. Contam. , vol.16 , pp. 481-495
    • Hall, R.L.1    Ford, R.A.2
  • 10
    • 0029439892 scopus 로고
    • Evaluation of certain food additives and contaminants
    • Forty-fourth Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 1995. Evaluation of certain food additives and contaminants. Forty-fourth Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 859. http://www.who.int/pcs/jecfa/ JECFA_publications.htm.
    • (1995) WHO Technical Report Series, No. 859
  • 11
    • 0031397771 scopus 로고    scopus 로고
    • Evaluation of certain food additives and contaminants
    • Forty-sixth Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 1997. Evaluation of certain food additives and contaminants. Forty-sixth Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 868. http://www.who.int/pcs/jecfa/ JECFA_publications.htm.
    • (1997) WHO Technical Report Series, No. 868
  • 12
    • 0032944673 scopus 로고    scopus 로고
    • Evaluation of certain food additives and contaminants
    • Forty-ninth Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 1999. Evaluation of certain food additives and contaminants. Forty-ninth Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 884. http://www.who.int/pcs/jecfa/ JECFA_publications.htm.
    • (1999) WHO Technical Report Series, No. 884
  • 13
    • 0012598758 scopus 로고    scopus 로고
    • Evaluation of certain food additives
    • Fifty-first Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 2000a. Evaluation of certain food additives. Fifty-first Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 891. http://www.who.int/pcs/jecfa/JECFA_publications.htm.
    • (2000) WHO Technical Report Series , vol.891
  • 14
    • 0034570162 scopus 로고    scopus 로고
    • Evaluation of certain food additives and contaminants
    • Fifty-third Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 2000b. Evaluation of certain food additives and contaminants. Fifty-third Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 896. http://www.who.int/pcs/jecfa/ JECFA_publications.htm.
    • (2000) WHO Technical Report Series, No. 896
  • 15
    • 0346453269 scopus 로고    scopus 로고
    • Evaluation of certain food additives and contaminants
    • Fifty-fifth Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 2001. Evaluation of certain food additives and contaminants. Fifty-fifth Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 901. http://www.who.int/pcs/jecfa/ JECFA_publications.htm.
    • (2001) WHO Technical Report Series, No. 901.
  • 16
    • 0036957105 scopus 로고    scopus 로고
    • Evaluation of certain food additives and contaminants
    • Fifty-seventh Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 2002a. Evaluation of certain food additives and contaminants. Fifty-seventh Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 909. http://www.who.int/pcs/jecfa/ JECFA_publications.htm.
    • (2002) WHO Technical Report Series, No. 909
  • 17
    • 0042236662 scopus 로고    scopus 로고
    • Evaluation of certain food additives
    • Fifty-ninth Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, 2002b. Evaluation of certain food additives. Fifty-ninth Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, No. 913. http://www.who.int/pcs/jecfa/JECFA_publications.htm.
    • (2002) WHO Technical Report Series, No. 913
  • 18
    • 0012598758 scopus 로고    scopus 로고
    • Evaluation of certain food additives
    • in press. Sixty-first Report of the Joint FAO/WHO Expert Committee on Food Additives.
    • JECFA, in press. Evaluation of certain food additives. Sixty-first Report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series.
    • WHO Technical Report Series
  • 19
    • 0034010667 scopus 로고    scopus 로고
    • Threshold of toxicological concern for chemical substances present in the diet: A practical tool for assessing the need for toxicity testing
    • Kroes R., Galli C.L., Munro I., Schilter B., Tran L.-A., Walker R., Würtzen G. Threshold of toxicological concern for chemical substances present in the diet: a practical tool for assessing the need for toxicity testing. Food Chem. Toxicol. 38:2000;255-312.
    • (2000) Food Chem. Toxicol. , vol.38 , pp. 255-312
    • Kroes, R.1    Galli, C.L.2    Munro, I.3    Schilter, B.4    Tran, L.-A.5    Walker, R.6    Würtzen, G.7
  • 22
    • 0036145053 scopus 로고    scopus 로고
    • Comparison of stochastic modelling of the intakes of intentionally added flavouring substances with theoretical added maximum daily intakes (TAMDI) and maximized survey-derived daily intakes (MSDI)
    • Lambe J., Cadby P., Gibney M. Comparison of stochastic modelling of the intakes of intentionally added flavouring substances with theoretical added maximum daily intakes (TAMDI) and maximized survey-derived daily intakes (MSDI). Food Addit. Contam. 19:2002;2-14.
    • (2002) Food Addit. Contam. , vol.19 , pp. 2-14
    • Lambe, J.1    Cadby, P.2    Gibney, M.3
  • 23
    • 0025185557 scopus 로고
    • Safety assessment procedures for indirect food additives: An overview. Report of a workshop
    • Munro I.C. Safety assessment procedures for indirect food additives: an overview. Report of a workshop. Regulat. Toxicol. Pharmacol. 12:1990;2-12.
    • (1990) Regulat. Toxicol. Pharmacol. , vol.12 , pp. 2-12
    • Munro, I.C.1
  • 24
    • 1842802552 scopus 로고    scopus 로고
    • A procedure for the safety evaluation of flavoring substances. Toxicological evaluation of certain food additives and contaminants
    • Prepared for the Joint FAO/WHO Expert Committee on Food Additives. Annex 5.
    • Munro, I.C., 1996. A procedure for the safety evaluation of flavoring substances. Toxicological evaluation of certain food additives and contaminants. Prepared for the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series, Number 35, Annex 5.
    • (1996) WHO Technical Report Series, Number 35
    • Munro, I.C.1
  • 25
    • 0035069048 scopus 로고    scopus 로고
    • Comparison of estimated daily per capita intakes of flavouring substances with no-observed-effect levels from animal studies
    • Munro I.C., Kennepohl E. Comparison of estimated daily per capita intakes of flavouring substances with no-observed-effect levels from animal studies. Food Chem. Toxicol. 39:2001;331-354.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 331-354
    • Munro, I.C.1    Kennepohl, E.2
  • 26
    • 0030250802 scopus 로고    scopus 로고
    • Correlation of structural class with no-observed effect levels: A proposal for establishing a threshold of concern
    • Munro I.C., Ford R.A., Kennepohl E., Sprenger J.G. Correlation of structural class with no-observed effect levels: a proposal for establishing a threshold of concern. Food Chem. Toxicol. 34:1996;829-867.
    • (1996) Food Chem. Toxicol. , vol.34 , pp. 829-867
    • Munro, I.C.1    Ford, R.A.2    Kennepohl, E.3    Sprenger, J.G.4
  • 27
    • 0032100545 scopus 로고    scopus 로고
    • Principles for the safety evaluation of flavouring substances
    • Munro I.C., Shubik P., Hall R. Principles for the safety evaluation of flavouring substances. Food Chem. Toxicol. 36:1998;529-540.
    • (1998) Food Chem. Toxicol. , vol.36 , pp. 529-540
    • Munro, I.C.1    Shubik, P.2    Hall, R.3
  • 28
    • 0032907217 scopus 로고    scopus 로고
    • A procedure for the safety evaluation of flavouring substances
    • Munro I.C., Kennepohl E., Kroes R. A procedure for the safety evaluation of flavouring substances. Food Chem. Toxicol. 37:1999;207-232.
    • (1999) Food Chem. Toxicol. , vol.37 , pp. 207-232
    • Munro, I.C.1    Kennepohl, E.2    Kroes, R.3
  • 30
    • 0001386160 scopus 로고    scopus 로고
    • Exposure estimation, toxicological requirements and risk assessment
    • van der Heijden, K., Younes, M., Fishbein, L., Miller, S. (Eds.), Marcel Dekker, New York
    • Renwick, A.G., 1999. Exposure estimation, toxicological requirements and risk assessment. In: van der Heijden, K., Younes, M., Fishbein, L., Miller, S. (Eds.), International Food Safety Handbook, Marcel Dekker, New York, pp. 59-94.
    • (1999) International Food Safety Handbook , pp. 59-94
    • Renwick, A.G.1
  • 32
    • 0011934822 scopus 로고
    • Principles for the assessment of risk to human health from exposure to chemicals
    • World Health Organization, Geneva.
    • WHO, 1987. Principles for the assessment of risk to human health from exposure to chemicals. Environmenal Health Criteria, 70. World Health Organization, Geneva. http://www.inchem.org/documents/ehc/ehc/ehc70.htm.
    • (1987) Environmenal Health Criteria , vol.70
  • 33
    • 0028641239 scopus 로고
    • Assessing human health risks of chemicals: Derivation of guidance values for health-based exposure limits
    • World Health Organization, Geneva.
    • WHO, 1994. Assessing human health risks of chemicals: derivation of guidance values for health-based exposure limits, Environmental Health Criteria, 170. World Health Organization, Geneva. http://www.inchem.org/documents/ehc/ ehc/ehc170.htm.
    • (1994) Environmental Health Criteria , vol.170


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.