-
1
-
-
0026714331
-
The anthracyclines: will we ever find a better doxorubicin?
-
Weiss R.B. The anthracyclines: will we ever find a better doxorubicin?. Semin. Oncol. 19 (1992) 670-686
-
(1992)
Semin. Oncol.
, vol.19
, pp. 670-686
-
-
Weiss, R.B.1
-
2
-
-
0021878134
-
Early and delayed clinical cardiotoxicity of doxorubicin
-
Buzdar A.U., Marcus C., Smith T.L., and Blumenschein G.R. Early and delayed clinical cardiotoxicity of doxorubicin. Cancer 55 (1985) 2761-2765
-
(1985)
Cancer
, vol.55
, pp. 2761-2765
-
-
Buzdar, A.U.1
Marcus, C.2
Smith, T.L.3
Blumenschein, G.R.4
-
3
-
-
0034721770
-
Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species
-
Kotamraju S., Konorev E.A., Joseph J., and Kalyanaraman B. Doxorubicin-induced apoptosis in endothelial cells and cardiomyocytes is ameliorated by nitrone spin traps and ebselen. Role of reactive oxygen and nitrogen species. J. Biol. Chem. 275 (2000) 33585-33592
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33585-33592
-
-
Kotamraju, S.1
Konorev, E.A.2
Joseph, J.3
Kalyanaraman, B.4
-
5
-
-
19544371393
-
Coenzyme Q10 for prevention of anthracycline-induced cardiotoxicity
-
Conklin K.A. Coenzyme Q10 for prevention of anthracycline-induced cardiotoxicity. Integr. Cancer Ther. 4 (2005) 110-130
-
(2005)
Integr. Cancer Ther.
, vol.4
, pp. 110-130
-
-
Conklin, K.A.1
-
6
-
-
0036897097
-
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
-
Bocci G., Nicolaou K.C., and Kerbel R.S. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res. 62 (2002) 6938-6943
-
(2002)
Cancer Res.
, vol.62
, pp. 6938-6943
-
-
Bocci, G.1
Nicolaou, K.C.2
Kerbel, R.S.3
-
7
-
-
0141990623
-
Anti-tumor efficacy of tumor vasculature targeted liposomal doxorubicin
-
Schiffelers R.M., Koning G.A., ten Hagen T.L., Fens M.H., Schraa A.J., Janssen A.P., Kok R.J., Molema G., and Storm G. Anti-tumor efficacy of tumor vasculature targeted liposomal doxorubicin. J. Control. Release 91 (2003) 115-122
-
(2003)
J. Control. Release
, vol.91
, pp. 115-122
-
-
Schiffelers, R.M.1
Koning, G.A.2
ten Hagen, T.L.3
Fens, M.H.4
Schraa, A.J.5
Janssen, A.P.6
Kok, R.J.7
Molema, G.8
Storm, G.9
-
8
-
-
10744233861
-
Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy
-
Pastorino F., Brignole C., Marimpietri D., Cilli M., Gambini C., Ribatti D., Longhi R., Allen T.M., Corti A., and Ponzoni M. Vascular damage and anti-angiogenic effects of tumor vessel-targeted liposomal chemotherapy. Cancer Res. 63 (2003) 7400-7409
-
(2003)
Cancer Res.
, vol.63
, pp. 7400-7409
-
-
Pastorino, F.1
Brignole, C.2
Marimpietri, D.3
Cilli, M.4
Gambini, C.5
Ribatti, D.6
Longhi, R.7
Allen, T.M.8
Corti, A.9
Ponzoni, M.10
-
9
-
-
4243907381
-
Doxorubicin-induced apoptosis: implications in cardiotoxicity
-
Kalyanaraman B., Joseph J., Kalivendi S., Wang S., Konorev E., and Kotamraju S. Doxorubicin-induced apoptosis: implications in cardiotoxicity. Mol. Cell. Biochem. 234-235 (2002) 119-124
-
(2002)
Mol. Cell. Biochem.
, vol.234-235
, pp. 119-124
-
-
Kalyanaraman, B.1
Joseph, J.2
Kalivendi, S.3
Wang, S.4
Konorev, E.5
Kotamraju, S.6
-
10
-
-
0036901361
-
Adriamycin-induced cardiomyocyte and endothelial cell apoptosis: in vitro and in vivo studies
-
Wu S., Ko Y.S., Teng M.S., Ko Y.L., A Hsu L., Hsueh C., Chou Y.Y., Liew C.C., and Lee Y.S. Adriamycin-induced cardiomyocyte and endothelial cell apoptosis: in vitro and in vivo studies. J. Mol. Cell. Cardiol. 34 (2002) 1595-1607
-
(2002)
J. Mol. Cell. Cardiol.
, vol.34
, pp. 1595-1607
-
-
Wu, S.1
Ko, Y.S.2
Teng, M.S.3
Ko, Y.L.4
A Hsu, L.5
Hsueh, C.6
Chou, Y.Y.7
Liew, C.C.8
Lee, Y.S.9
-
12
-
-
29044443481
-
p38 MAPK mediates inhibition of Bad via PP2A-dependent suppression of the MEK1/2-ERK1/2 survival pathway in TNF-α-induced endothelial apoptosis
-
Grethe S., and Pörn-Ares M.I. p38 MAPK mediates inhibition of Bad via PP2A-dependent suppression of the MEK1/2-ERK1/2 survival pathway in TNF-α-induced endothelial apoptosis. Cell. Signal. 18 (2006) 531-540
-
(2006)
Cell. Signal.
, vol.18
, pp. 531-540
-
-
Grethe, S.1
Pörn-Ares, M.I.2
-
13
-
-
0347997608
-
MAPK signal pathways in the regulation of cell proliferation in mammalian cells
-
Zhang W., and Liu H.T. MAPK signal pathways in the regulation of cell proliferation in mammalian cells. Cell Res. 12 (2002) 9-18
-
(2002)
Cell Res.
, vol.12
, pp. 9-18
-
-
Zhang, W.1
Liu, H.T.2
-
14
-
-
0035253794
-
Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells
-
Guise S., Braguer D., Carles G., Delacourte A., and Briand C. Hyperphosphorylation of tau is mediated by ERK activation during anticancer drug-induced apoptosis in neuroblastoma cells. J. Neurosci. Res. 63 (2001) 257-267
-
(2001)
J. Neurosci. Res.
, vol.63
, pp. 257-267
-
-
Guise, S.1
Braguer, D.2
Carles, G.3
Delacourte, A.4
Briand, C.5
-
15
-
-
0037066686
-
ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
-
Tang D., Wu D., Hirao A., Lahti J.M., Liu L., Mazza B., Kidd V.J., Mak T.W., and Ingram A.J. ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J. Biol. Chem. 277 (2002) 12710-12717
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12710-12717
-
-
Tang, D.1
Wu, D.2
Hirao, A.3
Lahti, J.M.4
Liu, L.5
Mazza, B.6
Kidd, V.J.7
Mak, T.W.8
Ingram, A.J.9
-
16
-
-
2442639165
-
Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death
-
Yeh P.Y., Chuang S.E., Yeh K.H., Song Y.C., Chang L.L., and Cheng A.L. Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death. Oncogene 23 (2004) 3580-3588
-
(2004)
Oncogene
, vol.23
, pp. 3580-3588
-
-
Yeh, P.Y.1
Chuang, S.E.2
Yeh, K.H.3
Song, Y.C.4
Chang, L.L.5
Cheng, A.L.6
-
17
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
-
Stephens L., Anderson K., Stokoe D., Erdjument-Bromage H., Painter G.F., Holmes A.B., Gaffney P.R., Reese C.B., McCormick F., Tempst P., Coadwell J., and Hawkins P.T. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science 279 (1998) 710-714
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjument-Bromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
Coadwell, J.11
Hawkins, P.T.12
-
18
-
-
0034708482
-
Akt/Protein Kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
-
Toker A., and Newton A.C. Akt/Protein Kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J. Biol. Chem. 275 (2000) 8271-8274
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8271-8274
-
-
Toker, A.1
Newton, A.C.2
-
19
-
-
0035920145
-
Regulation of Protein Kinase B/Akt-Serine 473 phosphorylation by integrin-linked kinase
-
Persad S., Attwell S., Gray V., Mawji N., Deng J.T., Leung D., Yan J., Sanghera J., Walsh M.P., and Dedhar S. Regulation of Protein Kinase B/Akt-Serine 473 phosphorylation by integrin-linked kinase. J. Biol. Chem. 276 (2001) 27462-27469
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 27462-27469
-
-
Persad, S.1
Attwell, S.2
Gray, V.3
Mawji, N.4
Deng, J.T.5
Leung, D.6
Yan, J.7
Sanghera, J.8
Walsh, M.P.9
Dedhar, S.10
-
20
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone M.H., Roy N., Stennicke H.R., Salvesen G.S., Franke T.F., Stanbridge E., Frisch S., and Reed J.C. Regulation of cell death protease caspase-9 by phosphorylation. Science 282 (1998) 1318-1321
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
Roy, N.2
Stennicke, H.R.3
Salvesen, G.S.4
Franke, T.F.5
Stanbridge, E.6
Frisch, S.7
Reed, J.C.8
-
21
-
-
0030702123
-
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
-
Datta S.R., Dudek H., Tao X., Masters S., Fu H., Gotoh Y., and Greenberg M.E. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91 (1997) 231-241
-
(1997)
Cell
, vol.91
, pp. 231-241
-
-
Datta, S.R.1
Dudek, H.2
Tao, X.3
Masters, S.4
Fu, H.5
Gotoh, Y.6
Greenberg, M.E.7
-
22
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor
-
Brunet A., Bonni A., Zigmond M.J., Lin M.Z., Juo P., Hu L.S., Anderson M.J., Arden K.C., Blenis J., and Greenberg M.E. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96 (1999) 857-868
-
(1999)
Cell
, vol.96
, pp. 857-868
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
Anderson, M.J.7
Arden, K.C.8
Blenis, J.9
Greenberg, M.E.10
-
23
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
-
Pap M., and Cooper G.M. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J. Biol. Chem. 273 (1998) 19929-19932
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
25
-
-
0038414629
-
TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways
-
Secchiero P., Gorelli A., Carnevale E., Milani D., Pandolfi A., Zella D., and Zauli G. TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 107 (2003) 2250-2256
-
(2003)
Circulation
, vol.107
, pp. 2250-2256
-
-
Secchiero, P.1
Gorelli, A.2
Carnevale, E.3
Milani, D.4
Pandolfi, A.5
Zella, D.6
Zauli, G.7
-
26
-
-
0347093421
-
Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3′-OH kinase-Akt pathway
-
Takeuchi K., and Ito F. Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3′-OH kinase-Akt pathway. J. Biol. Chem. 279 (2004) 892-900
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 892-900
-
-
Takeuchi, K.1
Ito, F.2
-
27
-
-
0033143385
-
How BAD phosphorylation is good for survival
-
Downward J. How BAD phosphorylation is good for survival. Nat. Cell Biol. 1 (1999) E33-E35
-
(1999)
Nat. Cell Biol.
, vol.1
-
-
Downward, J.1
-
28
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
-
Yang E., Zha J., Jockel J., Boise L.H., Thompson C.B., and Korsmeyer S.J. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80 (1995) 285-291
-
(1995)
Cell
, vol.80
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
30
-
-
0033120591
-
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A
-
Harada H., Becknell B., Wilm M., Mann M., Huang L.J., Taylor S.S., Scott J.D., and Korsmeyer S.J. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. Mol. Cell 3 (1999) 413-422
-
(1999)
Mol. Cell
, vol.3
, pp. 413-422
-
-
Harada, H.1
Becknell, B.2
Wilm, M.3
Mann, M.4
Huang, L.J.5
Taylor, S.S.6
Scott, J.D.7
Korsmeyer, S.J.8
-
32
-
-
0040056864
-
p21-activated kinase 1 phosphorylates the death agonist Bad and protects cells from apoptosis
-
Schürmann A., Mooney A.F., Sanders L.C., Sells M.A., Wang H.G., Reed J.C., and Bokoch G.M. p21-activated kinase 1 phosphorylates the death agonist Bad and protects cells from apoptosis. Mol. Cell Biol. 20 (2000) 453-461
-
(2000)
Mol. Cell Biol.
, vol.20
, pp. 453-461
-
-
Schürmann, A.1
Mooney, A.F.2
Sanders, L.C.3
Sells, M.A.4
Wang, H.G.5
Reed, J.C.6
Bokoch, G.M.7
-
33
-
-
0035859956
-
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD
-
Harada H., Andersen J.S., Mann M., Terada N., and Korsmeyer S.J. p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD. Proc. Natl. Acad. Sci. USA 98 (2001) 9666-9670
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9666-9670
-
-
Harada, H.1
Andersen, J.S.2
Mann, M.3
Terada, N.4
Korsmeyer, S.J.5
-
34
-
-
0001637870
-
Permanent cell line expressing human factor VIII-related antigen established by hybridization
-
Edgell C.J., McDonald C.C., and Graham J.B. Permanent cell line expressing human factor VIII-related antigen established by hybridization. Proc. Natl. Acad. Sci. USA 80 (1983) 3734-3737
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 3734-3737
-
-
Edgell, C.J.1
McDonald, C.C.2
Graham, J.B.3
-
35
-
-
0037192824
-
Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism
-
Lorenzo E., Ruiz-Ruiz C., Quesada A.J., Hernandez G., Rodriguez A., Lopez-Rivas A., and Redondo J.M. Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism. J. Biol. Chem. 277 (2002) 10883-10892
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10883-10892
-
-
Lorenzo, E.1
Ruiz-Ruiz, C.2
Quesada, A.J.3
Hernandez, G.4
Rodriguez, A.5
Lopez-Rivas, A.6
Redondo, J.M.7
-
36
-
-
0034040751
-
Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences
-
Follenzi A., Ailles L.E., Bakovic S., Geuna M., and Naldini L. Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences. Nat. Genet. 25 (2000) 217-222
-
(2000)
Nat. Genet.
, vol.25
, pp. 217-222
-
-
Follenzi, A.1
Ailles, L.E.2
Bakovic, S.3
Geuna, M.4
Naldini, L.5
-
37
-
-
0027936755
-
A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells
-
Han J., Lee J.D., Bibbs L., and Ulevitch R.J. A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells. Science 265 (1994) 808-811
-
(1994)
Science
, vol.265
, pp. 808-811
-
-
Han, J.1
Lee, J.D.2
Bibbs, L.3
Ulevitch, R.J.4
-
38
-
-
3442901352
-
Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression
-
Bardella C., Costa B., Maggiora P., Patane S., Olivero M., Ranzani G.N., De Bortoli M., Comoglio P.M., and Di Renzo M.F. Truncated RON tyrosine kinase drives tumor cell progression and abrogates cell-cell adhesion through E-cadherin transcriptional repression. Cancer Res. 64 (2004) 5154-5161
-
(2004)
Cancer Res.
, vol.64
, pp. 5154-5161
-
-
Bardella, C.1
Costa, B.2
Maggiora, P.3
Patane, S.4
Olivero, M.5
Ranzani, G.N.6
De Bortoli, M.7
Comoglio, P.M.8
Di Renzo, M.F.9
-
39
-
-
0022263591
-
Characterization of the cycle of iron-mediated electron transfer from Adriamycin to molecular oxygen
-
Gianni L., Zweier J.L., Levy A., and Myers C.E. Characterization of the cycle of iron-mediated electron transfer from Adriamycin to molecular oxygen. J. Biol. Chem. 260 (1985) 6820-6826
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 6820-6826
-
-
Gianni, L.1
Zweier, J.L.2
Levy, A.3
Myers, C.E.4
-
40
-
-
19244383998
-
Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin
-
Vasquez-Vivar J., Martasek P., Hogg N., Masters B.S., Pritchard Jr. K.A., and Kalyanaraman B. Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin. Biochemistry 36 (1997) 11293-11297
-
(1997)
Biochemistry
, vol.36
, pp. 11293-11297
-
-
Vasquez-Vivar, J.1
Martasek, P.2
Hogg, N.3
Masters, B.S.4
Pritchard Jr., K.A.5
Kalyanaraman, B.6
-
41
-
-
0035145860
-
N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells
-
Hashimoto S., Gon Y., Matsumoto K., Takeshita I., and Horie T. N-acetylcysteine attenuates TNF-alpha-induced p38 MAP kinase activation and p38 MAP kinase-mediated IL-8 production by human pulmonary vascular endothelial cells. Br. J. Pharmacol. 132 (2001) 270-276
-
(2001)
Br. J. Pharmacol.
, vol.132
, pp. 270-276
-
-
Hashimoto, S.1
Gon, Y.2
Matsumoto, K.3
Takeshita, I.4
Horie, T.5
-
42
-
-
10744227768
-
Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB203580, by alteration of one or more amino acids within the ATP binding pocket
-
Gum R.J., McLaughlin M.M., Kumar S., Wang Z., Bower M.J., Lee J.C., Adams J.L., Livi G.P., Goldsmith E.J., and Young P.R. Acquisition of sensitivity of stress-activated protein kinases to the p38 inhibitor, SB203580, by alteration of one or more amino acids within the ATP binding pocket. J. Biol. Chem. 273 (1998) 15605-15610
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15605-15610
-
-
Gum, R.J.1
McLaughlin, M.M.2
Kumar, S.3
Wang, Z.4
Bower, M.J.5
Lee, J.C.6
Adams, J.L.7
Livi, G.P.8
Goldsmith, E.J.9
Young, P.R.10
-
43
-
-
23044473622
-
2-terminal kinase to induce apoptosis
-
2-terminal kinase to induce apoptosis. Mol. Biol. Cell 16 (2005) 3821-3831
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 3821-3831
-
-
Panaretakis, T.1
Laane, E.2
Pokrovskaja, K.3
Björklund, A.C.4
Moustakas, A.5
Zhivotovsky, B.6
Heyman, M.7
Shoshan, M.C.8
Grander, D.9
-
44
-
-
0033974063
-
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway
-
Breitschopf K., Haendeler J., Malchow P., Zeiher A.M., and Dimmeler S. Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway. Mol. Cell. Biol. 20 (2000) 1886-1896
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1886-1896
-
-
Breitschopf, K.1
Haendeler, J.2
Malchow, P.3
Zeiher, A.M.4
Dimmeler, S.5
-
45
-
-
0034193343
-
A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents
-
Sanchez-Prieto R., Rojas J.M., Taya Y., and Gutkind J.S. A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents. Cancer Res. 60 (2000) 2464-2472
-
(2000)
Cancer Res.
, vol.60
, pp. 2464-2472
-
-
Sanchez-Prieto, R.1
Rojas, J.M.2
Taya, Y.3
Gutkind, J.S.4
-
46
-
-
0034608083
-
Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases
-
Kang Y.J., Zhou Z.X., Wang G.W., Buridi A., and Klein J.B. Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinases. J. Biol. Chem. 275 (2000) 13690-13698
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 13690-13698
-
-
Kang, Y.J.1
Zhou, Z.X.2
Wang, G.W.3
Buridi, A.4
Klein, J.B.5
-
47
-
-
15044342095
-
Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells
-
Poizat C., Puri P.L., Bai Y., and Kedes L. Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells. Mol. Cell. Biol. 25 (2005) 2673-2687
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2673-2687
-
-
Poizat, C.1
Puri, P.L.2
Bai, Y.3
Kedes, L.4
-
48
-
-
0038823730
-
Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines
-
Liem A.A., Appleyard M.V., O'Neill M.A., Hupp T.R., Chamberlain M.P., and Thompson A.M. Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines. Br. J. Cancer 88 (2003) 1281-1284
-
(2003)
Br. J. Cancer
, vol.88
, pp. 1281-1284
-
-
Liem, A.A.1
Appleyard, M.V.2
O'Neill, M.A.3
Hupp, T.R.4
Chamberlain, M.P.5
Thompson, A.M.6
-
49
-
-
3843074548
-
Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells
-
Zhao Y., You H., Yang Y., Wei L., Zhang X., Yao L., Fan D., and Yu Q. Distinctive regulation and function of PI 3K/Akt and MAPKs in doxorubicin-induced apoptosis of human lung adenocarcinoma cells. J. Cell. Biochem. 91 (2004) 621-632
-
(2004)
J. Cell. Biochem.
, vol.91
, pp. 621-632
-
-
Zhao, Y.1
You, H.2
Yang, Y.3
Wei, L.4
Zhang, X.5
Yao, L.6
Fan, D.7
Yu, Q.8
-
50
-
-
0035970041
-
Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction
-
Negoro S., Oh H., Tone E., Kunisada K., Fujio Y., Walsh K., Kishimoto T., and Yamauchi-Takihara K. Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction. Circulation 103 (2001) 555-561
-
(2001)
Circulation
, vol.103
, pp. 555-561
-
-
Negoro, S.1
Oh, H.2
Tone, E.3
Kunisada, K.4
Fujio, Y.5
Walsh, K.6
Kishimoto, T.7
Yamauchi-Takihara, K.8
-
51
-
-
0036193839
-
Bcl-xL reduces doxorubicin-induced myocardial damage but fails to control cardiac gene downregulation
-
Kunisada K., Tone E., Negoro S., Nakaoka Y., Oshima Y., Osugi T., Funamoto M., Izumi M., Fujio Y., Hirota H., and Yamauchi-Takihara K. Bcl-xL reduces doxorubicin-induced myocardial damage but fails to control cardiac gene downregulation. Cardiovasc. Res. 53 (2002) 936-943
-
(2002)
Cardiovasc. Res.
, vol.53
, pp. 936-943
-
-
Kunisada, K.1
Tone, E.2
Negoro, S.3
Nakaoka, Y.4
Oshima, Y.5
Osugi, T.6
Funamoto, M.7
Izumi, M.8
Fujio, Y.9
Hirota, H.10
Yamauchi-Takihara, K.11
-
52
-
-
0036830417
-
Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide
-
Simoes-Wüst A.P., Schürpf T., Hall J., Stahel R.A., and Zangemeister-Wittke U. Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide. Breast Cancer Res. Treat. 76 (2002) 157-166
-
(2002)
Breast Cancer Res. Treat.
, vol.76
, pp. 157-166
-
-
Simoes-Wüst, A.P.1
Schürpf, T.2
Hall, J.3
Stahel, R.A.4
Zangemeister-Wittke, U.5
-
53
-
-
0035839556
-
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells
-
Gratton J.P., Morales-Ruiz M., Kureishi Y., Fulton D., Walsh K., and Sessa W.C. Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells. J. Biol. Chem. 276 (2001) 30359-30365
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30359-30365
-
-
Gratton, J.P.1
Morales-Ruiz, M.2
Kureishi, Y.3
Fulton, D.4
Walsh, K.5
Sessa, W.C.6
-
54
-
-
0038342509
-
AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance
-
Yuan Z., Feldman R.I., Sussman G.E., Coppola D., Nicosia S.V., and Cheng J.Q. AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance. J. Biol. Chem. 278 (2003) 23432-23440
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23432-23440
-
-
Yuan, Z.1
Feldman, R.I.2
Sussman, G.E.3
Coppola, D.4
Nicosia, S.V.5
Cheng, J.Q.6
-
55
-
-
0043193866
-
Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis
-
Chiang C.W., Kanies C., Kim K.W., Fang W.B., Parkhurst C., Xie M., Henry T., and Yang E. Protein phosphatase 2A dephosphorylation of phosphoserine 112 plays the gatekeeper role for BAD-mediated apoptosis. Mol. Cell. Biol. 23 (2003) 6350-6362
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6350-6362
-
-
Chiang, C.W.1
Kanies, C.2
Kim, K.W.3
Fang, W.B.4
Parkhurst, C.5
Xie, M.6
Henry, T.7
Yang, E.8
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