Phosphorylation of p53 on Thr55 by ERK2 is necessary for doxorubicin-induced p53 activation and cell death

Oncogene

Volumn 23, Issue 20, 2004, Pages 3580-3588

  Yeh, Pei Yen ^a,b   Chuang, Shuang En ^c   Yeh, Kun Huei ^a,b,d   Song, Ying Chyi ^b   Chang, Lucia Ling Yuan ^b   Cheng, Ann Lii ^a,b,c  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^d FAR EASTERN MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Bcl 2; Doxorubicin; ERK2; p53; p53Thr55

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER CELL DESTRUCTION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANTIBIOTICS, ANTINEOPLASTIC; BCL-2-ASSOCIATED X PROTEIN; CELL DEATH; DOWN-REGULATION; DOXORUBICIN; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; THREONINE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 2442639165     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207426     Document Type: Article

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